Abstract:
OBJECTIVES:To determine whether metabolic syndrome is an independent predictor of decline in mobility in an elderly community sample. DESIGN:Biracial community-based prospective cohort study. SETTING:Urban and rural areas of central North Carolina. PARTICIPANTS:One thousand two hundred twenty-nine older African Americans and whites, mean age 77.0, who were participants in the Duke Established Populations for Epidemiologic Studies of the Elderly. MEASUREMENTS:Sociodemographic data and data on mobility (a subset of items from the Rosow-Breslau scale), depression (Center for Epidemiological Studies Depression Scale), self-report of medical conditions, body mass index, cognitive function (Short Portable Mental Status Questionnaire), blood pressure, height, and waist circumference. High-density lipoprotein cholesterol, triglycerides, and blood glucose were available from blood samples. Metabolic syndrome was calculated for subjects with complete data. RESULTS:Twenty-nine percent of the sample met criteria for metabolic syndrome. In bivariate analyses, age, sex, race, education, cognitive impairment, depression, impairment in mobility, history of stroke and heart disease, and metabolic syndrome at baseline were associated with a decline in mobility 4 years later. Regression analysis controlling for the above variables demonstrated that metabolic syndrome persisted as an independent and highly significant predictor of decline in mobility. CONCLUSION:These findings suggest that metabolic syndrome may be a distinct risk factor for mobility decline in community-dwelling older people.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Blazer DG,Hybels CF,Fillenbaum GGdoi
10.1111/j.1532-5415.2005.00607.xsubject
Has Abstractpub_date
2006-03-01 00:00:00pages
502-6issue
3eissn
0002-8614issn
1532-5415pii
JGS607journal_volume
54pub_type
杂志文章abstract::In 1976, 130 patients aged 70 or older were admitted to the Coronary Care Unit (CCU) at Toronto Western Hospital. Arrhythmias were noted in all but 24 percent. Digoxin was given to 53 patients, lidocaine to 24, propranolol to 28, and quinidine to 11. In 2 patients, cardioversion by direct current was required for supr...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1979.tb06032.x
更新日期:1979-05-01 00:00:00
abstract::Leaders of geriatric programs at academic health centers (AHCs) face several challenges in seeking support for clinical program development. These challenges relate to how revenues from Medicare activities flow within AHCs. Typically, clinical departments such as the Department of Medicine see a very small proportion ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.1532-5415.2002.50174.x
更新日期:2002-04-01 00:00:00
abstract:BACKGROUND:The need for mentorship in aging research among postdoctoral trainees and junior faculty across medical disciplines and subspecialties is increasing, yet senior personnel with expertise in aging are lacking to fulfill the traditional dyadic mentorship role. Facilitated peer mentorship is grounded in collabor...
journal_title:Journal of the American Geriatrics Society
pub_type: 评论,杂志文章
doi:10.1111/jgs.15792
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVES:To test whether Stepping On, a multifaceted community-based program using a small-group learning environment, is effective in reducing falls in at-risk people living at home. DESIGN:A randomized trial with subjects followed for 14 months. SETTING:The interventions were conducted in community venues, with a...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2004.52411.x
更新日期:2004-09-01 00:00:00
abstract:OBJECTIVES:To address the competing risk of death in longitudinal studies of older persons, we demonstrate sensitivity analyses that evaluate robustness of associations between exposures and three outcome types: dichotomous, count, and time to event. DESIGN:A secondary analysis of data from a prospective cohort study....
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15697
更新日期:2019-02-01 00:00:00
abstract::Older women are often sexually active, but physicians caring for older women rarely address sexual concerns. Although women's desire for sex declines with age, a majority of older women rate sex as having importance in their lives. Women identify emotional intimacy as an important reason for engaging in sexual relatio...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15198
更新日期:2018-03-01 00:00:00
abstract::Contemporary, systematic approaches to injury prevention are presented as guides for considering needless death and disability of older people because of falls, burns, and vehicular crashes. Injury results from an unfavorable relationship between etiologic agent and host within a particular environment setting. Abnorm...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1982.tb07102.x
更新日期:1982-04-01 00:00:00
abstract:OBJECTIVES:To explore associations between serum 25-hydroxyvitamin D (25(OH)D) levels and a wide range of health conditions, physical performance measures, disability, and mortality in a large epidemiological study to identify an optimum range for 25(OH)D concentrations. DESIGN:Cross-sectional study, with additional p...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.12693
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVES:To apply diagnostic criteria for mild cognitive impairment (MCI) to a geographically representative sample, to estimate the prevalence of MCI, and to estimate 10-year trajectories of incident disability for cognitively intact participants and subgroups with MCI. DESIGN:Prospective cohort; 10 years of follow...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2005.53566.x
更新日期:2005-11-01 00:00:00
abstract::Osteoporosis and sarcopenia are degenerative diseases frequently associated with aging. The loss of bone and muscle results in significant morbidity, so preventing or attenuating osteoporosis and sarcopenia is an important public health goal. Dietary protein is crucial for development of bone and muscle, and recent ev...
journal_title:Journal of the American Geriatrics Society
pub_type: 历史文章,杂志文章
doi:10.1111/j.1532-5415.2009.02285.x
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVES:To estimate population norms for use in assessment of individuals in relation to their age-matched peers using true longitudinal patterns of decline. DESIGN:Longitudinal study of 10 years of follow-up data from the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS) on the most commonly ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1532-5415.2007.01216.x
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVES:To evaluate the longer term changes in executive functioning among participants with cardiovascular disease (CVD) risk factors and cognitive impairments with no dementia (CIND) randomized to a diet and exercise intervention. DESIGN:A 2 (Exercise) × 2 (Dietary Approaches to Stop Hypertension [DASH] eating pl...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/jgs.16252
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVES:To compare the longitudinal changes in maximal aerobic capacity (VO2max) in healthy middle aged and older athletes and sedentary men. DESIGN:A cohort study with mean follow-up of 8.7 years (range 4.0-12.8). SETTING:Outpatient research at a tertiary hospital. PARTICIPANTS:Forty-two healthy, middle aged, an...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.1532-5415.2001.t01-1-49276.x
更新日期:2001-12-01 00:00:00
abstract:OBJECTIVES:To develop and evaluate a modification of the Fried frailty assessment using population-independent cutpoints and to determine frailty prevalence of community-dwelling elderly people in a German population. DESIGN:Cross-sectional analysis of 8-year follow-up data of a large German cohort study. SETTING:Saa...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2012.04192.x
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVES:To determine whether the association between impaired cognition and greater risk of incident stroke is also observed when cognitive impairment is defined using different criteria for mild cognitive impairment (MCI). DESIGN:Prospective cohort study with 10 years of follow-up. SETTING:Large multicentre study...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/jgs.14878
更新日期:2017-08-01 00:00:00
abstract::A history of systolic (greater than or equal to 160 mm Hg) or diastolic (greater than or equal to 90 mm Hg) hypertension, diabetes mellitus (fasting venous plasma glucose greater than or equal to 140 mg/dl), a history of cigarette smoking, fasting serum total cholesterol greater than or equal to 200 mg/dl and greater ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1987.tb01311.x
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of dental problems in Paget's patients and in a control population without Paget's disease. The relationship of localization of bony involvement of Paget's disease with the prevalence of dental, auditory, visual, and smell changes is examined. DESIGN:Cross-sectional national surve...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1995.tb06618.x
更新日期:1995-12-01 00:00:00
abstract::Self-administered questionnaires were sent to all faculty and staff members of the departments of internal medicine and psychiatry in a school of medicine. The questionnaires asked for information about personal characteristics, practice characteristics, and interest in teaching geriatrics. Included also were measures...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1982.tb03703.x
更新日期:1982-01-01 00:00:00
abstract:OBJECTIVES:To describe decade- long trends (1999-2009) in the rates of not undergoing cardiac catheterization and percutaneous coronary intervention (PCI) in individuals aged 65 and older presenting with an ST-segment elevation acute myocardial infarction (STEMI) and factors associated with not undergoing these procedu...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/jgs.13399
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVES:To clarify the association between cholesterol and noncardiovascular mortality and to evaluate how this association varies across age groups. DESIGN:Prospective population-based cohort study. SETTING:Rotterdam, the Netherlands. PARTICIPANTS:Adults aged 55 to 99 (N = 5,750). MEASUREMENTS:Participants were...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2011.03593.x
更新日期:2011-10-01 00:00:00
abstract::The benefits of prophylactic aspirin therapy to prevent cardiovascular and cerebrovascular disease in asymptomatic individuals remains unclear. The rationale for developing a multicentered, double-blind, placebo-controlled clinical trial to determine whether low-dose aspirin (100 mg daily) prevents cardiovascular and ...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1532-5415.1991.tb02494.x
更新日期:1991-05-01 00:00:00
abstract:BACKGROUND:Previous research has identified several barriers faced by clinicians in detecting and reporting elder abuse, such as lack of knowledge about the process to report suspected cases of abuse and lack of access to experts to consult with. A novel intervention was designed and tested that embedded two Adult Prot...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16433
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVES:Many elderly persons have drug benefits with coverage gaps, such as in Medicare Part D. Because beneficiaries who have such gaps must pay all drug costs, an accurate knowledge of gap thresholds and communication with providers about exceeding caps is important for elderly persons to manage out-of-pocket drug...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2009.02244.x
更新日期:2009-05-01 00:00:00
abstract::Two concurrent studies of geriatric outpatients who received diagnoses of depression were conducted. In the first, patients were treated with one of two tricyclic antidepressants or with a placebo. In the second, patients were assigned to groups receiving either psychodynamic group therapy or cognitive-behavioral grou...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1982.tb01987.x
更新日期:1982-11-01 00:00:00
abstract:OBJECTIVE:The literature suggests that Medicare health maintenance organization (HMO) patients may have poorer outcomes with formal home-health care than do fee-for-service (FFS) patients, but it is unclear whether this is related to case-mix or quality. Our objective was to compare the home-health care outcomes for HM...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1998.tb01083.x
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVE:We examined predictors of hospital and 6-month mortality in older Medical Intensive Care Unit (MICU) patients with particular attention to age and functional status. Age is generally thought to be strongly associated with intensive care outcomes, but this relationship may be confounded by age-related changes....
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1991.tb04452.x
更新日期:1991-09-01 00:00:00
abstract:OBJECTIVES:To compare endothelium-dependent vasomotor response in healthy younger and older subjects without classic cardiovascular risk factors, with high and normal fasting homocysteine (tHcy) levels. DESIGN:We compared endothelium-dependent vasodilatation, using ultrasound, in healthy younger (aged 18-40) and older...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.1532-5415.2002.50255.x
更新日期:2002-06-01 00:00:00
abstract::The Mini-Mental State Examination and the WAIS-R were administered to 105 patients in the early stages of Alzheimer's disease. MMSE scores correlated 0.83 with full scale IQ, which indicates that the MMSE may be a reasonable alternative measure of overall intellectual functioning in Alzheimer patients, for whom more e...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1988.tb04020.x
更新日期:1988-06-01 00:00:00
abstract:OBJECTIVES:To examine the relationship between cognitive function and self-reported oral health-related quality of life (HRQoL) in community-dwelling older adults. DESIGN:Cross-sectional. SETTING:Community in West Virginia. PARTICIPANTS:Two hundred twenty-six community-dwelling older adults. MEASUREMENTS:Oral HRQoL...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.12402
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Social media platforms are promising sources for large quantities of participant-driven research data and circumvent some common challenges when conducting dementia research. This study provides a summary of key considerations and recommendations about using these platforms as research tools for d...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16790
更新日期:2020-12-01 00:00:00