Abstract：
OBJECTIVES:To address the competing risk of death in longitudinal studies of older persons, we demonstrate sensitivity analyses that evaluate robustness of associations between exposures and three outcome types: dichotomous, count, and time to event. DESIGN:A secondary analysis of data from a prospective cohort study. SETTING:Community-based data from the Precipitating Events Project in New Haven, CT. PARTICIPANTS:Persons 70 years and older who were initially community dwelling and without disability in the four basic activities of daily living (N = 754). MEASUREMENTS:Missing outcome values from decedents were multiply imputed under different scenarios. Three outcomes were examined: dichotomous fall-related hospitalization (FRH); a count (0-13) of total disability in each of the 6 months after discharge; and days to functional recovery among those whose disability worsened in the hospital. Each outcome had a different exposure: for dichotomous, indicators of being overweight or obese; for count, frailty from the Fried phenotype (0-5, where not frail = 0, prefrail = 1-2, and frail = 3-5); for days to recovery, vision impairment. RESULTS:For FRH, being overweight or obese lost significance when decedents were kept in the risk pool without outcome events for over 10 years. For disability count and time to recovery, with follow-up of 6 months, exposures only lost significance under highly implausible clinical scenarios. CONCLUSION:This method facilitates evaluation of potential bias from the competing risk of death in longitudinal studies for nondeath outcomes that are not necessarily time to event. Results suggest that death introduces substantive bias when long-term follow-up results in cumulatively high levels of mortality. J Am Geriatr Soc 67:357-362, 2019.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Murphy TE,Gill TM,Leo-Summers LS,Gahbauer EA,Pisani MA,Ferrante LEdoi
10.1111/jgs.15697subject
Has Abstractpub_date
2019-02-01 00:00:00pages
357-362issue
2eissn
0002-8614issn
1532-5415journal_volume
67pub_type
杂志文章abstract：OBJECTIVES:To understand the natural history of frailty after an aggressive surgical intervention, kidney transplantation (KT). DESIGN:Prospective cohort study (December 2008-March 2014). SETTING:Baltimore, Maryland. PARTICIPANTS:Kidney transplantation recipients (N = 349). MEASUREMENTS:The Fried frailty score was ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.13657
更新日期：2015-10-01 00:00:00
abstract：OBJECTIVE:To investigate the prevalence of hypoalbuminemia and hypoprealbuminemia in hospitalized, elderly, skilled nursing facility residents and to correlate these findings with clinical outcomes. DESIGN:Prospective cohort study. SETTING:A 300-bed community hospital. PARTICIPANTS:Eighty-one hospitalized, skilled n...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1993.tb01893.x
更新日期：1993-05-01 00:00:00
abstract：BACKGROUND:Coffee and tea are two of the most widely consumed beverages worldwide and have been associated with reduced risk of mortality in some studies. However, it is unknown whether consumption of these beverages is associated with survival to an advanced age. OBJECTIVE:To examine associations of coffee and tea co...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.16467
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVES:To explore associations between serum 25-hydroxyvitamin D (25(OH)D) levels and a wide range of health conditions, physical performance measures, disability, and mortality in a large epidemiological study to identify an optimum range for 25(OH)D concentrations. DESIGN:Cross-sectional study, with additional p...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.12693
更新日期：2014-03-01 00:00:00
abstract：OBJECTIVES:Knowledge of male sexual function is somewhat limited because of a lack of current population-based data. This study provides information on sexual function and satisfaction in a population-based sample of men. METHODS:Men aged 40 to 79 years (n = 2115) were selected randomly from the Olmsted County populat...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1995.tb07009.x
更新日期：1995-10-01 00:00:00
abstract：OBJECTIVE:To evaluate the usefulness of standardized neuropsychological tests in the psychometric differentiation of patients with very mild or mild Alzheimer's Disease (AD) and/or major depression presenting in a tertiary clinic with memory/attention complaints. DESIGN:Controlled prospective clinicoexperimental desig...
journal_title：Journal of the American Geriatrics Society
pub_type： 临床试验,杂志文章
doi：10.1111/j.1532-5415.1995.tb07402.x
更新日期：1995-11-01 00:00:00
abstract：PURPOSE:The objective of this meta-analysis of randomized controlled trials (RCTs) of terazosin versus placebo in men with benign prostatic hyperplasia (BPH) was to evaluate the effect of terazosin on lower urinary tract symptoms. BACKGROUND:BPH is common in older men; more than 90% of men aged 70 and older suffer fro...
journal_title：Journal of the American Geriatrics Society
pub_type： 评论,杂志文章
doi：10.1046/j.1532-5415.2003.51120.x
更新日期：2003-03-01 00:00:00
abstract：OBJECTIVES:To determine the prognostic value of apathy for mortality in patients of somatic (SC) and dementia special care (DSC) nursing home (NH) units. DESIGN:Longitudinal design, secondary analyses of a 2-year, cluster-randomized trial with six measurements, approximately 4 months in between. SETTING:SC and DSC-un...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1111/jgs.15007
更新日期：2017-10-01 00:00:00
abstract：OBJECTIVES:The purpose of this study was to determine if reported nighttime sleep problems and daytime sleepiness were associated with reported falling during the previous 12 months in a representatively sampled older adult population. DESIGN:Random-digit dial telephone survey. SETTING:Representatively sampled older ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2000.tb02596.x
更新日期：2000-10-01 00:00:00
abstract：:Japan implemented a mandatory social long-term care insurance (LTCI) system in 2000, making long-term care services a universal entitlement for every senior. Although this system has grown rapidly, reflecting its popularity among seniors and their families, it faces several challenges, including skyrocketing costs. Th...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,评审
doi：10.1111/j.1532-5415.2007.01281.x
更新日期：2007-09-01 00:00:00
abstract：:The population of minority older adults is going to explode over the next four decades. Older adults from racial and ethnic minorities face persistent and pervasive health disparities. Health disparities exert a huge fiscal burden on the nation. The national financial cost of health disparities for the years 2002 to 2...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.15939
更新日期：2019-05-01 00:00:00
abstract：OBJECTIVES:To study whether subjective memory deterioration is associated with future dementia in older people. DESIGN:A population-based prospective cohort study begun in 1994 with biennial follow-up interviews. SETTING:Community-based members of Group Health Cooperative, a large health maintenance organization in t...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2004.52568.x
更新日期：2004-12-01 00:00:00
abstract：:An operational definition of frailty is important for clinical care, research, and policy planning. The literature on the clinical definitions, screening tools, and severity measures of frailty were systematically reviewed as part of the Canadian Initiative on Frailty and Aging. Searches of MEDLINE from 1997 to 2009 w...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,评审
doi：10.1111/j.1532-5415.2011.03597.x
更新日期：2011-11-01 00:00:00
abstract：:The relation of serum albumin concentration to age was assessed in a series of hospitalized medical patients. Those with disease states (e.g., dysproteinemia, renal insufficiency, hepatic dysfunction, malnutrition) potentially associated with abnormal serum albumin levels were excluded, leaving a study population of 1...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1979.tb01715.x
更新日期：1979-01-01 00:00:00
abstract：OBJECTIVE:To examine the predictive value of psychosocial factors as risk factors for all-cause mortality. DESIGN:A community-based longitudinal cohort study: The Honolulu Heart Program. SETTING:Population-based study conducted in Oahu, Hawaii. PARTICIPANTS:Three thousand four hundred and ninety-seven men age 71 to ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1046/j.1532-5415.2001.49148.x
更新日期：2001-06-01 00:00:00
abstract：OBJECTIVES:To examine the associations between typology of family relationship and risk of elder mistreatment (EM). DESIGN:Population-based epidemiological cross-sectional study. SETTING:Community-dwelling older adults in the greater Chicago area. PARTICIPANTS:A total of 3157 US older Chinese immigrants. MEASUREMEN...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.15892
更新日期：2019-08-01 00:00:00
abstract：OBJECTIVES:To examine transitions that individuals with dementia experience longitudinally and to identify points of care when transitions are highest and the factors that contribute to those transitions. DESIGN:Population-based 10-year retrospective cohort study from 2000 to 2011. SETTING:General community. PARTICI...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.14033
更新日期：2016-03-01 00:00:00
abstract：BACKGROUND:Although frailty status is dynamic, whether improvements in frailty predict mortality is unknown. OBJECTIVE:Describe 1-year changes in a frailty index (FI) and association with 48-month mortality. DESIGN:Secondary analysis of the National Health in Aging Trends Study. SETTING:Community. PARTICIPANTS:Five...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.17002
更新日期：2020-12-29 00:00:00
abstract：:Thyroid disease in the aged, both hypothyroidism and hyperthyroidism, may be subtle or may be present with no clinical symptoms and signs, and is therefore difficult to diagnose on the basis of clinical evaluation. The help of the laboratory is essential in making the diagnosis of disease of the thyroid. Therapeutic s...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,评审
doi：10.1111/j.1532-5415.1993.tb06488.x
更新日期：1993-12-01 00:00:00
abstract：:As part of an interview survey of a defined population of 3,097 rural persons 65 years and older (the Iowa 65 + Rural Health Study), the prevalence and functional correlates of specifically defined low back pain were studied. Low back pain was reported by 23.6 per cent of the women and 18.4 per cent of the men in the ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1985.tb02855.x
更新日期：1985-01-01 00:00:00
abstract：OBJECTIVE:To develop and validate the Physical Performance and Mobility Examination (PPME), an observer-administered, performance-based instrument assessing 6 domains of physical functioning and mobility for hospitalized elderly. DESIGN:Development of a pass-fail and 3-level scoring system and training manuals for the...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1994.tb06535.x
更新日期：1994-07-01 00:00:00
abstract：OBJECTIVES:To design a value-driven, interprofessional inpatient geriatric consultation program coordinated with systems-level changes and studied outcomes and costs. DESIGN:Propensity-matched case-control study of older adults hospitalized at an academic medical center (AMC) who did or did not receive geriatric consu...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.15473
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVES:To measure end-of-life (EOL) care preferences and advance care planning (ACP) in older Latinos and to examine the relationship between culture-based attitudes and extent of ACP. DESIGN:Cross-sectional interview. SETTING:Twenty-two senior centers in greater Los Angeles. PARTICIPANTS:One hundred forty-seven...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2010.02853.x
更新日期：2010-06-01 00:00:00
abstract：OBJECTIVES:The purpose of this study was to test whether an intervention combining increased daytime physical activity with improvement in the nighttime environment improves sleep and decreases agitation in nursing home residents. DESIGN:A randomized trial. SETTING:One community nursing home in the Los Angeles, Calif...
journal_title：Journal of the American Geriatrics Society
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1532-5415.1999.tb03833.x
更新日期：1999-07-01 00:00:00
abstract：:A trial by any means that can possibly prevent or retard the development of arteriosclerosis is to be recommended. Arteriosclerosis is the chief cause of strokes and heart attacks. The heavy evening meal now in vogue is characteristically rich in animal fats. Normal digestion is at its peak at about the seventh hour, ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1978.tb02404.x
更新日期：1978-06-01 00:00:00
abstract：OBJECTIVE:To review (1) Changes in cardiac impulse generation, conduction, and ventricular filling in normal aging and disease; (2) Pacemaker technology and nomenclature; (3) Expert guidelines about pacemaker use; (4) Studies of pacemaker effectiveness and utilization. DESIGN:Articles were identified through a Medline...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,评审
doi：10.1111/j.1532-5415.1994.tb01760.x
更新日期：1994-03-01 00:00:00
abstract：OBJECTIVES:To assess clinical outcomes and identify risk factors for mortality in older adults with Staphylococcus aureus bloodstream infection (SAB). DESIGN:Retrospective review. SETTING:University of Michigan Health System, Ann Arbor. PARTICIPANTS:All patients aged 80 and older with SAB between January 2004 and Ju...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2009.02666.x
更新日期：2010-02-01 00:00:00
abstract：:As part of a study of long-term institutional care of the elderly, this report presents salient data concerning 193 elderly applicants. Physicians play an important role in decisions to apply for such care. More than half of the applicants and about 80% of their family members approved of the proposed move. The number...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1976.tb04293.x
更新日期：1976-04-01 00:00:00
abstract：OBJECTIVES:To evaluate and summarize the evidence of muscle weakness as a risk factor for falls in older adults. DESIGN:Random-effects meta-analysis. SETTING:English-language studies indexed in MEDLINE and CINAHL (1985-2002) under the key words aged and accidental falls and risk factors; bibliographies of retrieved p...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,meta分析,评审
doi：10.1111/j.1532-5415.2004.52310.x
更新日期：2004-07-01 00:00:00
abstract：OBJECTIVES:To quantify the relationship between indwelling devices (urinary catheters, feeding tubes, and peripherally inserted central catheters) and carriage of antimicrobial-resistant pathogens in nursing home residents. DESIGN:Cross-sectional. SETTING:Community nursing home in Southeast Michigan. PARTICIPANTS:Re...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2007.01468.x
更新日期：2007-12-01 00:00:00
