Abstract:
OBJECTIVES:To explore associations between serum 25-hydroxyvitamin D (25(OH)D) levels and a wide range of health conditions, physical performance measures, disability, and mortality in a large epidemiological study to identify an optimum range for 25(OH)D concentrations. DESIGN:Cross-sectional study, with additional prospective data on falls and mortality. SETTING:Concord Health and Ageing in Men Project, Sydney, Australia. PARTICIPANTS:Community-dwelling men aged 70 and older (N = 1,659). MEASUREMENTS:Serum 25(OH)D levels, general health status, self-reported diseases, physical performance measures, disability (activities of daily living and instrumental activities of daily living) and falls. RESULTS:Fair, poor, and very poor health; self-reported diabetes mellitus; hyperglycemia; depression; muscle weakness; poor balance; and all-cause mortality were all associated with serum 25(OH)D levels less than 50 nmol/L, even after adjustment for confounding. The findings also suggest that, in older men, for a wide range of health conditions, physical performance measures, disability, falls, and mortality, the optimum range of 25(OH)D is between 50.0 and 74.9 nmol/L, with no additional benefit for 25(OH)D levels of 75.0 nmol/L or greater. CONCLUSION:Programs aimed at achieving an optimum range of serum 25(OH)D at levels between 50.0 and 74.9 nmol/L may have overall health benefits and such levels are adequate for older men.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Hirani V,Cumming RG,Naganathan V,Blyth F,Le Couteur DG,Handelsman DJ,Waite LM,Seibel MJdoi
10.1111/jgs.12693subject
Has Abstractpub_date
2014-03-01 00:00:00pages
417-25issue
3eissn
0002-8614issn
1532-5415journal_volume
62pub_type
杂志文章abstract::An operational definition of frailty is important for clinical care, research, and policy planning. The literature on the clinical definitions, screening tools, and severity measures of frailty were systematically reviewed as part of the Canadian Initiative on Frailty and Aging. Searches of MEDLINE from 1997 to 2009 w...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/j.1532-5415.2011.03597.x
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVES:To determine whether increasing kyphosis angle was independently associated with poorer mobility as measured according to the Timed Up and Go Test (TUG), after controlling for other established risk factors. DESIGN:Prospective cohort study. SETTING:Eleven clinical centers in the United States. PARTICIPANT...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1532-5415.2010.03214.x
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND/ OBJECTIVES:Prior research has shown that social engagement is beneficial to older adults' health and well-being. This study examined the association between environmental factors and social engagement of older Chinese immigrants in the United States. SAMPLE:A cross-sectional data set of Chinese immigrants ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15899
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVES:To validate the Harmful Behaviors Scale (HBS) as a measure of direct and indirect self-destructive behaviors in nursing home residents and to determine the prevalence of self-destructive behaviors and their relationship to other variables. DESIGN:A cross-sectional study. SETTING:Eleven nursing homes in the...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1046/j.1532-5415.2002.50070.x
更新日期:2002-02-01 00:00:00
abstract::Historically, the medical subspecialties have not focused on the needs of older adults. This has changed with the implementation of initiatives to integrate geriatrics and aging research into the medical and surgical subspecialties and with the establishment of a home for internal medicine specialists within the annua...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.14708
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Observation stays are increasingly common for older adults, yet little is known about the extent to which they are being used as the Centers for Medicare and Medicaid Services (CMS) originally intended for unscheduled or acute problems and whether different types of services are reflected in curre...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16441
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVES:To perform a systematic review to determine the effectiveness of interventions designed to reduce potentially inappropriate prescribing (PIP) in community-dwelling older adults. DESIGN:Systematic review and narrative synthesis. SETTING:Primary and community care. PARTICIPANTS:Community-dwelling older adul...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/jgs.14133
更新日期:2016-06-01 00:00:00
abstract::Coronavirus disease 2019 (COVID-19) continues to impact older adults disproportionately, from severe illness and hospitalization to increased mortality risk. Concurrently, concerns about potential shortages of healthcare professionals and health supplies to address these needs have focused attention on how resources a...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16537
更新日期:2020-06-01 00:00:00
abstract::Our objective was to determine the outcome of onsite CPR in elderly patients receiving institutional care who had access to 24-hour on-site full ACLS capability. We used a retrospective chart and CPR protocol review of all patients who received CPR during the study period; these were patients or residents in a multi-l...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1993.tb02052.x
更新日期:1993-02-01 00:00:00
abstract:OBJECTIVES:To assess use of urinary collection devices (external, intermittent, and indwelling catheters; pads or briefs) and examine predictors of indwelling catheters in skilled nursing facilities (SNFs). DESIGN:Retrospective cohort study. SETTING:SNFs in California, Florida, Michigan, New York, and Texas. PARTICI...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2008.01675.x
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVES:To review studies investigating cochlear implant (CI) outcomes in older adults, and to develop a conceptual framework demonstrating important interactions between characteristics of hearing disability, aging, and the CI intervention. DESIGN:Review of English literature with titles containing the words "coch...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/j.1532-5415.2012.04150.x
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVES:To determine whether serum calcium is associated with cognitive function in elderly individuals in the general population. DESIGN:Prospective follow-up study of two independent, population-based cohorts. SETTING:The Rotterdam Study (median follow-up 11 years) and the Leiden 85-plus Study (median follow-up ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2007.01418.x
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to report on the prevalence, incidence and prognosis of left ventricular hypertrophy (LVH) on the electrocardiogram (ECG) in a cohort of ambulatory older men and women. DESIGN:A prospective, longitudinal study of 10 years duration with ECGs obtained at baseline and on an annua...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1996.tb01437.x
更新日期:1996-05-01 00:00:00
abstract:OBJECTIVES:To examine the effects of caring for a spouse with dementia on the caregiver's risk for incident dementia. DESIGN:Population-based study of incident dementia in spouses of persons with dementia. SETTING:Rural county in northern Utah. PARTICIPANTS:Two thousand four hundred forty-two subjects (1,221 married...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2010.02806.x
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVES:To investigate whether midlife and older women who reported prior-year physical abuse, verbal abuse, or both abuse types had higher mortality risk than peers who did not report prior-year abuse. DESIGN:Retrospective analysis. SETTING:Community. PARTICIPANTS:One hundred sixty-thousand six hundred seventy-s...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2009.02429.x
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVES:To determine the effect of four vitamin D supplement doses on falls risk in elderly nursing home residents. DESIGN:Secondary data analysis of a previously conducted randomized clinical trial. SETTING:Seven hundred twenty-five-bed long-term care facility. PARTICIPANTS:One hundred twenty-four nursing home r...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2007.01048.x
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVES:The specific goals of the study were to compare three health status measures among older adults for their correlations with similar scales and to examine whether extreme (positive) health states might lead to measurement problems. We also report on practical administration and response problems among older a...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1995.tb05569.x
更新日期:1995-09-01 00:00:00
abstract:OBJECTIVES:To use a simple measure of activities of daily living, wounds, and indwelling devices (urinary catheter, feeding tube) to predict prevalent, new, and intermittent multidrug-resistant organism (MDRO) acquisition in nursing home (NH) residents. DESIGN:Secondary analysis, prospective cohort study. SETTING:Sou...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.13353
更新日期:2015-04-01 00:00:00
abstract::Absorption of folates, vitamin B6, pantothenate, and riboflavin from a natural food source (yeast) and from synthetic folylmonoglutamate was studied in 24 elderly subjects (age range, 73 to 101 years) and in 12 healthy younger subjects (age range, 24 to 42 years). All subjects absorbed riboflavin, vitamin B6, and pant...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1978.tb01962.x
更新日期:1978-05-01 00:00:00
abstract:BACKGROUND:Quality of human immunodeficiency virus (HIV) care in nursing homes (NHs) has never been measured. DESIGN:A cross-sectional study. SETTING:NHs. PARTICIPANTS:A total of 203 NHs and 1375 persons living with HIV. MEASUREMENTS:Medicare claims from 2011 to 2013 were linked to assessments of resident health, p...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16359
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVES:To assess whether the relationship between antidepressant adherence and coronary artery disease (CAD) hospitalizations varied between older and younger adults with depression. DESIGN:Retrospective cohort study. SETTING:Department of Veterans Affairs outpatient clinics nationwide. PARTICIPANTS:Chronically ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.12849
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVES:To evaluate medication use, out-of-pocket spending, and medication switching during the transition period for patients dually eligible for Medicaid and Medicare (dual eligibles). DESIGN:Time-trend analysis, using segmented linear regression. SETTING:Patient-level pharmacy dispensing data from January 2005 ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2008.02025.x
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVES:To compare the prevalence and predictors of caregiver esteem and burden during two different stages of care recipients' illnesses-advanced chronic illness and the last year of life. DESIGN:Longitudinal, observational cohort study. SETTING:Community sample recruited from outpatient clinics at Duke Universit...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.12841
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVES:To investigate the cause of worse survival in older patients after myocardial infarction (MI). DESIGN:Prospective 18-month and longer follow-up study of a cohort of 167 patients (mean age +/- standard deviation 58 +/- 12, including 71 aged >or=65) with acute MI for cardiac events, defined as cardiac death, ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.1532-5415.2002.t01-1-50302.x
更新日期:2002-07-01 00:00:00
abstract::Review of 8428 autopsies (1870 for known cancer) showed that 68 patients had had multiple primary malignant tumors (MPMT). Those 68 cases represented 0.8 per cent of all autopsies done, 3.6 per cent of all cancer autopsies. Diagnosis of MPMT was made only at autopsy in 24 cases (35.3 per cent). Thirty-six patients wer...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1982.tb03364.x
更新日期:1982-12-01 00:00:00
abstract:BACKGROUND:The need for mentorship in aging research among postdoctoral trainees and junior faculty across medical disciplines and subspecialties is increasing, yet senior personnel with expertise in aging are lacking to fulfill the traditional dyadic mentorship role. Facilitated peer mentorship is grounded in collabor...
journal_title:Journal of the American Geriatrics Society
pub_type: 评论,杂志文章
doi:10.1111/jgs.15792
更新日期:2019-04-01 00:00:00
abstract::This article provides a comprehensive review of aromatase inhibitors (AIs) for geriatricians, because it appears that more elderly women will be using these drugs in the near future. Computerized literature searches of Medline were conducted through May 2003. Key words/phrases included in the literature searches were ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/j.1532-5415.2004.52171.x
更新日期:2004-04-01 00:00:00
abstract:OBJECTIVES:To study how well the scoring on each item of the MMSE relates to the sum-score when the purpose is to identify persons with cognitive impairment, and to identify an equally effective subset of MMSE items for predicting cognitive impairment. DESIGN:Retrospective survey of MMSE data for 850 elderly. SETTING...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1992.tb01804.x
更新日期:1992-11-01 00:00:00
abstract:OBJECTIVES:To clarify the effect of tooth loss on development of all-cause dementia and its subtypes in an elderly Japanese population. DESIGN:Prospective cohort study. SETTING:The Hisayama Study, Japan. PARTICIPANTS:Community-dwelling Japanese adults without dementia aged 60 and older (N = 1,566) were followed for ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.14791
更新日期:2017-05-01 00:00:00
abstract::Hip fractures in older adults are a common event, leading to substantial morbidity and mortality. Hip fractures have been previously described as a "geriatric, rather than orthopedic disease." Patients with this condition have a high prevalence of comorbidity and a high risk of complications from surgery, and for this...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2008.01770.x
更新日期:2008-07-01 00:00:00