Abstract:
OBJECTIVES:To explore associations between serum 25-hydroxyvitamin D (25(OH)D) levels and a wide range of health conditions, physical performance measures, disability, and mortality in a large epidemiological study to identify an optimum range for 25(OH)D concentrations. DESIGN:Cross-sectional study, with additional prospective data on falls and mortality. SETTING:Concord Health and Ageing in Men Project, Sydney, Australia. PARTICIPANTS:Community-dwelling men aged 70 and older (N = 1,659). MEASUREMENTS:Serum 25(OH)D levels, general health status, self-reported diseases, physical performance measures, disability (activities of daily living and instrumental activities of daily living) and falls. RESULTS:Fair, poor, and very poor health; self-reported diabetes mellitus; hyperglycemia; depression; muscle weakness; poor balance; and all-cause mortality were all associated with serum 25(OH)D levels less than 50 nmol/L, even after adjustment for confounding. The findings also suggest that, in older men, for a wide range of health conditions, physical performance measures, disability, falls, and mortality, the optimum range of 25(OH)D is between 50.0 and 74.9 nmol/L, with no additional benefit for 25(OH)D levels of 75.0 nmol/L or greater. CONCLUSION:Programs aimed at achieving an optimum range of serum 25(OH)D at levels between 50.0 and 74.9 nmol/L may have overall health benefits and such levels are adequate for older men.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Hirani V,Cumming RG,Naganathan V,Blyth F,Le Couteur DG,Handelsman DJ,Waite LM,Seibel MJdoi
10.1111/jgs.12693subject
Has Abstractpub_date
2014-03-01 00:00:00pages
417-25issue
3eissn
0002-8614issn
1532-5415journal_volume
62pub_type
杂志文章abstract:OBJECTIVES:To examine the extent to which elderly individuals use various skilled care facilities after coronary artery bypass grafting (CABG). DESIGN:Retrospective cohort study. SETTING:State of Michigan from 1997 to 1998. PARTICIPANTS:Residents aged 65 and older enrolled in Medicare who underwent CABG. MEASUREMEN...
journal_title:Journal of the American Geriatrics Society
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doi:10.1111/j.1532-5415.2005.53356.x
更新日期:2005-07-01 00:00:00
abstract:OBJECTIVES:Patients undergoing hip fracture surgery have a 10 times increased risk of stroke compared with the general population. We aimed to evaluate the association between the CHA2 DS2 -VASc (congestive heart failure, hypertension, age ≥75 years, diabetes, previous stroke/TIA [transient ischemic attack]/systemic em...
journal_title:Journal of the American Geriatrics Society
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journal_title:Journal of the American Geriatrics Society
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doi:10.1111/j.1532-5415.1993.tb06735.x
更新日期:1993-06-01 00:00:00
abstract:OBJECTIVES:To determine the effect of biofeedback (BFB) therapy on psychological burden of urge urinary incontinence (UI) and whether prior depression or current depressive symptoms affect older women's response to BFB. DESIGN:Secondary analysis of an ongoing trial. SETTING:Academic medical center. PARTICIPANTS:Fort...
journal_title:Journal of the American Geriatrics Society
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更新日期:2007-12-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
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更新日期:2009-04-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
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doi:10.1111/j.1532-5415.2000.tb02596.x
更新日期:2000-10-01 00:00:00
abstract:OBJECTIVES:To determine whether the association between impaired cognition and greater risk of incident stroke is also observed when cognitive impairment is defined using different criteria for mild cognitive impairment (MCI). DESIGN:Prospective cohort study with 10 years of follow-up. SETTING:Large multicentre study...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
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更新日期:2017-08-01 00:00:00
abstract:OBJECTIVES:To describe the prevalence of visual and auditory impairment in frail older persons and to evaluate the association between sensory impairment and overall functional status. DESIGN:Prospective patient evaluation and retrospective analysis of data. SETTING:The outpatient geriatric assessment clinic of a uni...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1999.tb07432.x
更新日期:1999-11-01 00:00:00
abstract:OBJECTIVES:To determine whether patient age is associated with differences in flexible bronchoscopy technique and tolerance. DESIGN:Prospective cohort study. SETTING:University hospital system. PARTICIPANTS:One thousand three hundred fifty-eight adults, including 219 (16.1%) aged 70 and older, undergoing bronchoscop...
journal_title:Journal of the American Geriatrics Society
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更新日期:2003-07-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
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doi:10.1111/j.1532-5415.1998.tb01073.x
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVE:To determine if older pilots forgot more about a learned flight task after a 10-month delay than did younger pilots and if the anticipated greater skill loss led older pilots' performance to be more disrupted by alcohol. DESIGN:Repeated measures comparative group design examining the effects of alcohol versu...
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doi:10.1111/j.1532-5415.1994.tb06852.x
更新日期:1994-06-01 00:00:00
abstract:BACKGROUND:Coffee and tea are two of the most widely consumed beverages worldwide and have been associated with reduced risk of mortality in some studies. However, it is unknown whether consumption of these beverages is associated with survival to an advanced age. OBJECTIVE:To examine associations of coffee and tea co...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16467
更新日期:2020-09-01 00:00:00
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doi:10.1111/j.1532-5415.2000.tb05003.x
更新日期:2000-05-01 00:00:00
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doi:10.1111/j.1532-5415.2004.52217.x
更新日期:2004-05-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1986.tb04318.x
更新日期:1986-05-01 00:00:00
abstract:OBJECTIVES:To determine the relationship between prealbumin, nutrient intake, and indicators of inflammation for recuperative and rehabilitative care patients. DESIGN:Prospective cohort. SETTING:Recuperative Care Unit within a Veterans Administration Nursing Home Care Unit. PARTICIPANTS:One hundred eleven men (100 w...
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doi:10.1111/j.1532-5415.2008.01789.x
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVES:To determine the distribution of influenza vaccine coverage in the United States in 2008. DESIGN:Cross-sectional analysis. SETTING:The 2008 Behavioral Risk Factor Surveillance Survey, which employs random-digit dialing to interview noninstitutionalized adults in the United States and territories. PARTICIP...
journal_title:Journal of the American Geriatrics Society
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更新日期:2010-07-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1992.tb01831.x
更新日期:1992-01-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
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更新日期:1975-03-01 00:00:00
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更新日期:2014-01-01 00:00:00
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更新日期:2010-12-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
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doi:10.1111/j.1532-5415.1996.tb02437.x
更新日期:1996-02-01 00:00:00
abstract:OBJECTIVES:To determine whether a distance coaching course on improving nursing home incontinence care could be replicated and brought to scale with a larger group of nursing homes without sacrificing outcomes. DESIGN:The study collected descriptive and comparative data. SETTING:Fourteen nursing homes in the original...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2012.03939.x
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVES:To evaluate the association between insulin resistance (IR) and executive dysfunction in a large, population-based study of older persons without diabetes mellitus (DM) or dementia. DESIGN:Cross-sectional study. SETTING:Outpatient clinic in Greve in Chianti and Bagno a Ripoli, Italy. PARTICIPANTS:A total ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2004.52466.x
更新日期:2004-10-01 00:00:00
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doi:10.1046/j.1532-5415.2001.49212.x
更新日期:2001-08-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2011.03499.x
更新日期:2011-08-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/jgs.16205
更新日期:2020-01-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
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更新日期:2008-10-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
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doi:10.1111/jgs.12613
更新日期:2014-01-01 00:00:00