Genetics: modes of reproduction and genetic analysis.

Abstract:

:Classical and reverse genetics remain invaluable tools for the scientific investigation of model organisms. Genetic analysis of endoparasites is generally difficult because the sexual adults required for crossing and other manipulations are usually hidden within their host. Strongyloides spp. and Parastrongyloides spp. are notable exceptions to this and their free-living adults offer unique opportunities to manipulate these parasites experimentally. Here I review the modes of inheritance in the two generations of Strongyloides/Parastrongyloides and I discuss the opportunities and the limitations of the currently available methodology for the genetic analysis of these two genera.

journal_name

Parasitology

journal_title

Parasitology

authors

Streit A

doi

10.1017/S0031182016000342

subject

Has Abstract

pub_date

2017-03-01 00:00:00

pages

316-326

issue

3

eissn

0031-1820

issn

1469-8161

pii

S0031182016000342

journal_volume

144

pub_type

杂志文章,评审
  • Serial passage of Eimeria tenella and E. necatrix in turkey embryos.

    abstract::The serial passage of 3 strains of Eimeria from the chicken in embryonating turkey embryos is reported here. All 3 strains increased their reproduction in turkey embryos; reproduction being equal to or better than the same lines maintained in chicken embryos. Pathogenicity and immunogenicity trials conducted in chicke...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s003118200005037x

    authors: Kogut MH,Gore TC,Long PL

    更新日期:1983-04-01 00:00:00

  • Detection of Neospora caninum in aborted bovine fetuses and dam blood samples by nested PCR and ELISA and seroprevalence in Beijing and Tianjin, China.

    abstract::Neospora caninum infection is a significant cause of abortion in cattle. We investigated the tissue distribution of N. caninum in aborted bovine fetuses and dam blood samples by a nested PCR assay, and compared the nested PCR with ELISA in the diagnosis of N. caninum infection. In total, 26 aborted fetuses and 813 blo...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182009990813

    authors: Yao L,Yang N,Liu Q,Wang M,Zhang W,Qian WF,Hu YF,Ding J

    更新日期:2009-09-01 00:00:00

  • Purification and characterization of a 47 kDa protease from Schistosoma mansoni cercarial secretion.

    abstract::Fractionation of Schistosoma mansoni cercariae gland secretion on a Sephadex G-150 column followed by a Superose-12 column in an FPLC system, isolated a 47 kDa protease which migrated as a single band on SDS-PAGE gels. A monoclonal antibody (MAb) was produced which recognizes only the 47 kDa protease, and an immuno-af...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000074138

    authors: Chavez-Olortegui C,Resende M,Tavares CA

    更新日期:1992-10-01 00:00:00

  • Impact of chemical structure of flavanol monomers and condensed tannins on in vitro anthelmintic activity against bovine nematodes.

    abstract::Plants containing condensed tannins (CT) may have potential to control gastrointestinal nematodes (GIN) of cattle. The aim was to investigate the anthelmintic activities of four flavan-3-ols, two galloyl derivatives and 14 purified CT fractions, and to define which structural features of CT determine the anti-parasiti...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182015001912

    authors: Desrues O,Fryganas C,Ropiak HM,Mueller-Harvey I,Enemark HL,Thamsborg SM

    更新日期:2016-04-01 00:00:00

  • Strongyloides ratti: studies of 75Se-labelled larvae of the homogonic strain in female hosts.

    abstract::A prediction of the hypothesis of Wilson (1977, 1980 a, b) to account for larval migration of homogonic Strongyloides ratti in the host is that the pattern of invasion of the mammary gland of a lactating rat will be quantitatively similar on both sides and independent of the point of entry into the body. Twenty-one su...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000052744

    authors: Wilson PA,Simpson NE

    更新日期:1982-06-01 00:00:00

  • Long-read sequencing improves assembly of Trichinella genomes 10-fold, revealing substantial synteny between lineages diverged over 7 million years.

    abstract::Genome assemblies can form the basis of comparative analyses fostering insight into the evolutionary genetics of a parasite's pathogenicity, host-pathogen interactions, environmental constraints and invasion biology; however, the length and complexity of many parasite genomes has hampered the development of well-resol...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182017000348

    authors: Thompson PC,Zarlenga DS,Liu MY,Rosenthal BM

    更新日期:2017-09-01 00:00:00

  • Towards a comprehensive simulation model of malaria epidemiology and control.

    abstract::Planning of the control of Plasmodium falciparum malaria leads to a need for models of malaria epidemiology that provide realistic quantitative prediction of likely epidemiological outcomes of a wide range of control strategies. Predictions of the effects of control often ignore medium- and long-term dynamics. The com...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182008000371

    authors: Smith T,Maire N,Ross A,Penny M,Chitnis N,Schapira A,Studer A,Genton B,Lengeler C,Tediosi F,de Savigny D,Tanner M

    更新日期:2008-11-01 00:00:00

  • Field evidence for density-dependent facilitation amongst Ixodes ricinus ticks feeding on sheep.

    abstract::Engorged Ixodes ricinus nymphs collected from sheep resident in an upland UK field site were significantly lighter than nymphs that engorged on previously tick-naïve sheep, indicating that site-resident sheep continually exposed to ticks acquired anti-tick resistance. The weights of engorged nymphs that fed on natural...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182001001081

    authors: Ogden NH,Casey AN,French NP,Adams JD,Woldehiwet Z

    更新日期:2002-02-01 00:00:00

  • Properties and localization of chitin synthase in Ascaris suum eggs.

    abstract::Investigations were carried out into the properties and localization of chitin synthase (EC 2.4.1.16) in connection with the formation of Ascaris suum egg-shells. The chitin synthase of eggs exhibited properties very similar to those found in other chitin-synthesizing organisms. It was stimulated by the presence of AT...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000063575

    authors: Dubinský P,Rybos M,Turceková L

    更新日期:1986-02-01 00:00:00

  • A second peak of egg excretion in Strongyloides ratti-infected rats: its origin and biological meaning.

    abstract::In Strongyloides ratti-infected rats, 2 peaks of egg excretion were observed; a large one with maximum egg production on days 7-8 of infection and a small more inconspicuous one around day 25. The second peak, which had been ignored in most studies, was produced by adults in the caecum and the colon. The adults were l...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182099004631

    authors: Kimura E,Shintoku Y,Kadosaka T,Fujiwara M,Kondo S,Itoh M

    更新日期:1999-08-01 00:00:00

  • Vector survival and parasite infection: the effect of Wuchereria bancrofti on its vector Culex quinquefasciatus.

    abstract::This paper investigates a cohort of 2187 laboratory reared Culex quinquefasciatus fed on 69 human volunteers, including 59 persons with different levels of Wuchereria bancrofti microfilariae and 10 without microfilaria. Mosquitoes were followed until death. Mosquito survival was analysed in relation to the level of mi...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182004005153

    authors: Krishnamoorthy K,Subramanian S,Van Oortmarssen GJ,Habbema JD,Das PK

    更新日期:2004-07-01 00:00:00

  • Cytokine and immunoglobulin subclass responses of rats to infection with Eimeria nieschulzi.

    abstract::SIV rats infected with a high dose (50,000 oocysts) of Eimeria nieschulzi displayed clinical symptoms of coccidiosis such as diarrhoea (days 6 and 7 post-primary infection) and weight loss (days 6-8 post-primary infection) and were completely immune to challenge with a similar dose. The ability of rats to produce tumo...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000064593

    authors: Smith NC,Ovington KS,Deplazes P,Eckert J

    更新日期:1995-07-01 00:00:00

  • Morphological and molecular characterization of Plasmodium cathemerium (lineage PADOM02) from the sparrow Passer domesticus with complete sporogony in Culex pipiens complex.

    abstract::Avian malaria is a mosquito-borne disease caused by Plasmodium spp. protozoa. Although these parasites have been extensively studied in North America and Eurasia, knowledge on the diversity of Plasmodium, its vectors and avian hosts in Africa is scarce. In this study, we report on natural malarial infections in free-r...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182020000566

    authors: Aly MZY,Mohamed III,Sebak SI,Vanstreels RET,El Gendy AM

    更新日期:2020-08-01 00:00:00

  • Soil-transmitted helminth infections in school children from Cocle Province, Republic of Panama.

    abstract::A survey was carried out to determine values for the prevalence and intensity of infection of intestinal helminths in children living in Cocle Province, Republic of Panama. The data set consisted of the results of microscopic examinations (modified Kato Katz technique) of stool samples collected in November 1987 from ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000058741

    authors: Robertson LJ,Crompton DW,Walters DE,Nesheim MC,Sanjur D,Walsh EA

    更新日期:1989-10-01 00:00:00

  • Glucose-restriction increases Trichomonas vaginalis cellular damage towards HeLa cells and proteolytic activity of cysteine proteinases (CPs), such as TvCP2.

    abstract::Trichomonas vaginalis induces cellular damage to the host cells (cytotoxicity) through the proteolytic activity of multiple proteinases of the cysteine type (CPs). Some CPs are modulated by environmental factors such as iron, zinc, polyamines, etc. Thus, the goal of this study was to assess the effect of glucose on T....

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182019000209

    authors: Miranda-Ozuna JFT,Rivera-Rivas LA,Cárdenas-Guerra RE,Hernández-García MS,Rodríguez-Cruz S,González-Robles A,Chavez-Munguía B,Arroyo R

    更新日期:2019-08-01 00:00:00

  • Future trends in diagnosis using laboratory-on-a-chip technologies.

    abstract::There has been an enormous growth in the development of biotechnological applications, where advances in the techniques of microelectronic fabrication and the technologies of miniaturization and integration in semiconductor industries are being applied to the production of Laboratory-on-a-Chip devices. The aim of this...

    journal_title:Parasitology

    pub_type: 杂志文章,评审

    doi:10.1017/s0031182099004126

    authors: Talary MS,Burt JP,Pethig R

    更新日期:1998-01-01 00:00:00

  • Mitochondria of mammalian Plasmodium spp.

    abstract::Highly purified mitochondrial fractions have been isolated from the intraerythrocytic stages of two mammalian Plasmodium spp., Plasmodium yoelii of rodents and Plasmodium falciparum of man. Mitochondria of the former parasite are cristate whereas those of the latter are essentially acristate. Isolated mitochondria fro...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000060297

    authors: Fry M,Beesley JE

    更新日期:1991-02-01 00:00:00

  • Comparison of cysteine peptidase activities in Trichobilharzia regenti and Schistosoma mansoni cercariae.

    abstract::Cercariae of the bird schistosome Trichobilharzia regenti and of the human schistosome Schistosoma mansoni employ proteases to invade the skin of their definitive hosts. To investigate whether a similar proteolytic mechanism is used by both species, cercarial extracts of T. regenti and S. mansoni were biochemically ch...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182007002910

    authors: Kasný M,Mikes L,Dalton JP,Mountford AP,Horák P

    更新日期:2007-10-01 00:00:00

  • Protease inhibitors and haemagglutinins associated with resistance to the protozoan parasite, Perkinsus marinus, in the Pacific oyster, Crassostrea gigas.

    abstract::Perkinsus marinus is a protozoan responsible for dramatic mortality in the Eastern oyster, Crassostrea virginica, but not in the Pacific oyster, C. gigas. To understand the host-parasite relationship, we inoculated P. marinus trophozoites into the shell cavity of C. gigas and measured, over 2 months, (i) intensity of ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182002002135

    authors: Romestand B,Corbier F,Roch P

    更新日期:2002-10-01 00:00:00

  • A global sensitivity analysis for African sleeping sickness.

    abstract::African sleeping sickness is a parasitic disease transmitted through the bites of tsetse flies of the genus Glossina. We constructed mechanistic models for the basic reproduction number, R0, of Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense, respectively the causative agents of West and East African h...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182010001496

    authors: Davis S,Aksoy S,Galvani A

    更新日期:2011-04-01 00:00:00

  • Molecular characterization of Thelastomatoidea (Nematoda: Oxyurida) from cockroaches in Australia.

    abstract::A molecular approach was used to genetically characterize 5 species (Aoruroides queenslandensis, Blattophila sphaerolaima, Cordonicola gibsoni, Desmicola ornata and Leidynemella fusiformis) belonging to the superfamily Thelastomatoidea (Nematoda: Oxyurida), a group of pinworms that parasitizes terrestrial arthropods. ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182006009978

    authors: Jex AR,Hu M,Rose HA,Schneider M,Cribb TH,Gasser RB

    更新日期:2006-07-01 00:00:00

  • Immune responses to infections with coccidia in chickens: gut hypersensitivity.

    abstract::Sporulated oocysts or oocyst hulls of Eimeria acervulina given via the crop, and oocyst juice or sporozoites inoculated directly into the intestinal lumen, were tested for their effects on the hypersensitivity of the intestines of immunized and susceptible birds. Only viable sporozoites consistently caused an increase...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000047132

    authors: Rose ME,Long PL,Bradley JW

    更新日期:1975-12-01 00:00:00

  • The effect of Trichinella spiralis infection on the mechanical properties of the mammalian diaphragm.

    abstract::Trichinella spiralis larvae infect and develop within skeletal muscle cells causing major changes to their mechanical properties. The aim of this investigation was to determine the effects of T. spiralis on the power output and fatigue resistance of the mammalian diaphragm under conditions simulating in vivo operation...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000067585

    authors: Harwood CL,Young IS,Lee DL,Altringham JD

    更新日期:1996-12-01 00:00:00

  • Cytochemical studies on nuclear DNA of four eucoccidian parasites, Isospora (Toxoplasma) gondii, Eimeria tenella, Sarcocystis cruzi and Plasmodium berghei.

    abstract::Feulgen-pararosaniline (SO2) staining was performed on stages in the life-cycle of Isospora (Toxoplasma) gondii, Eimeria tenella, Sarcocystis cruzi and Plasmodium berghei. The fluorescence emission of the stained DNA in nuclei of these stages was examined and compared with absorption microscopy measurements at 560 nm ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000054305

    authors: Cornelissen AW,Overdulve JP,Van der Ploeg M

    更新日期:1984-02-01 00:00:00

  • Changes in the somatic musculature of the 4th-stage larvae of Ascaris suum Goeze, 1782 (Nematoda: Ascaridoidea) developing in swine.

    abstract::Fourth-stage larvae of Ascaris suum, recovered from piglets at 11-22 days post-infection (p.i.), were examined by light microscopy for changes in the somatic musculature. During this time the estimated total number of muscle cells in the body increases from approximately 600 to 21 000 cells. This non-eutelic developme...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s003118200005441x

    authors: O'Grady RT

    更新日期:1984-02-01 00:00:00

  • Evidence that primary infection of Charollais sheep with Toxoplasma gondii may not prevent foetal infection and abortion in subsequent lambings.

    abstract::A study carried out on a sheep farm examined whether Toxoplasma gondii foetal infection and associated abortion occur in successive lambings. We identified 29 ewes that gave birth to lambs on at least 2 successive years over our study period, 2000-2003. Tissue samples from the progeny of these ewes were analysed by PC...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182007003721

    authors: Morley EK,Williams RH,Hughes JM,Thomasson D,Terry RS,Duncanson P,Smith JE,Hide G

    更新日期:2008-02-01 00:00:00

  • High diversity of fish ectoparasitic monogeneans (Dactylogyrus) in the Iberian Peninsula: a case of adaptive radiation?

    abstract::The epicontinental fauna of the Iberian Peninsula is strongly influenced by its geographical history. As the possibilities for dispersion of organisms into and from this region were (and still are) limited, the local fauna consists almost exclusively of endemic species. Almost all Iberian freshwater fishes of the fami...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182020000050

    authors: Benovics M,Desdevises Y,Šanda R,Vukić J,Scheifler M,Doadrio I,Sousa-Santos C,Šimková A

    更新日期:2020-04-01 00:00:00

  • Allosteric control of pyrimidine transport in Hymenolepis diminuta: an unusual kinetic isotope effect.

    abstract::A thymine-uracil transport system is present in the plasma membrane brush-border of the tapeworm, Hymenolepis diminuta. The relation between initial uptake and substrate concentration of either thymine or uracil was sigmoidal when 2-14C-labelled substrates were used. In contrast, absorption kinetics of methyl-14C- and...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000052641

    authors: Uglem GL,Dupre RK,Harley JP

    更新日期:1983-10-01 00:00:00

  • Impaired health status and increased incidence of diseases in Toxoplasma-seropositive subjects - an explorative cross-sectional study.

    abstract::The global seroprevalence of latent toxoplasmosis is estimated to be higher than 30%. The presence of slowly dividing parasites in tissue cysts located mainly in immunoprivileged organs was long considered asymptomatic. Recently, many studies have shown that latent Toxoplasma infections could have serious impacts on h...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182016001785

    authors: Flegr J,Escudero DQ

    更新日期:2016-12-01 00:00:00

  • Expression of LPG and GP63 by different developmental stages of Leishmania major in the sandfly Phlebotomus papatasi.

    abstract::Development and forward migration of Leishmania parasites in the sandfly gut is accompanied by morphological transformation to highly motile, non-dividing 'metacyclic' forms. Previous studies in vitro have demonstrated that this metacyclogenesis is associated with developmentally regulated changes in expression of two...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000060522

    authors: Davies CR,Cooper AM,Peacock C,Lane RP,Blackwell JM

    更新日期:1990-12-01 00:00:00