Abstract:
PURPOSE:Focal therapy in low-risk prostate cancer may provide the best balance between cancer control and quality of life preservation. As a minimally invasive approach performed under TRUS guidance, brachytherapy is an appealing framework for focal therapy. However, the contrast in TRUS images is generally insufficient to distinguish the target lesion from normal prostate tissue. MRI usually offers a much better contrast between the lesion and surrounding tissues. Registration between TRUS and MRI may therefore significantly improve lesion targeting capability in focal prostate brachytherapy. In this paper, we present a deformable registration framework for the accurate fusion of TRUS and MRI prostate volumes under large deformations arising from dissimilarities in diameter, shape and orientation between endorectal coils and TRUS probes. METHODS:Following pose correction by a RANSAC implementation of the ICP algorithm, TRUS and MRI Prostate contour points are represented by a 3D extension of the shape-context descriptor and matched by the Hungarian algorithm. Eventually, a smooth free-form warping is computed by fitting a 3D B-spline mesh to the set of matched points. RESULTS:Quantitative validation of the registration accuracy is provided on a retrospective set of ten real cases, using as landmarks either brachytherapy seeds (six cases) or external beam radiotherapy fiducials (four cases) implanted and visible in both modalities. The average registration error between the landmarks was 2.49 and 3.20 mm, for the brachytherapy and external beam sets, respectively, that is less than the MRI voxels' long axis length ([Formula: see text]). The overall average registration error (for brachytherapy and external beam datasets together) was 2.56 mm. CONCLUSIONS:The proposed method provides a promising framework for TRUS-MRI registration in focal prostate brachytherapy.
journal_name
Int J Comput Assist Radiol Surgauthors
Mayer A,Zholkover A,Portnoy O,Raviv G,Konen E,Symon Zdoi
10.1007/s11548-016-1380-9subject
Has Abstractpub_date
2016-06-01 00:00:00pages
1015-23issue
6eissn
1861-6410issn
1861-6429pii
10.1007/s11548-016-1380-9journal_volume
11pub_type
杂志文章abstract:PURPOSE:The interaction with interventional imaging systems within a sterile environment is a challenging task for physicians. Direct physician-machine interaction during an intervention is rather limited because of sterility and workspace restrictions. METHODS:We present a gesture-controlled projection display that e...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-015-1215-0
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:For planning surgical interventions at the spine affected by osteoporosis, accurate information about the local bone quality in terms of anchorage strength for implants is very important. Based on previous work on automated bone quality assessment on the proximal femur with a completely automated model-based ...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-009-0287-0
更新日期:2009-05-01 00:00:00
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journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-017-1672-8
更新日期:2018-02-01 00:00:00
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journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-019-01926-0
更新日期:2019-04-01 00:00:00
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journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
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更新日期:2019-03-01 00:00:00
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journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
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更新日期:2017-06-01 00:00:00
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journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-013-0897-4
更新日期:2013-11-01 00:00:00
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journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
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更新日期:2016-08-01 00:00:00
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journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
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更新日期:2018-07-01 00:00:00
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更新日期:2020-05-01 00:00:00
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更新日期:2016-01-01 00:00:00
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更新日期:2019-05-01 00:00:00
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更新日期:2016-12-01 00:00:00
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更新日期:2021-01-01 00:00:00
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journal_title:International journal of computer assisted radiology and surgery
pub_type: 已发布勘误
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更新日期:2020-03-01 00:00:00
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更新日期:2018-02-01 00:00:00
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更新日期:2019-06-01 00:00:00
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更新日期:2018-06-01 00:00:00
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更新日期:2018-11-01 00:00:00