Abstract：
:The role of glutathione S-transferase Mu 1 (GSTM1) in the biomonitoring of polycyclic aromatic hydrocarbons (PAHs) is not clear. Our purpose has been to evaluate the influence of GSTM1 genotypes on 1-hydroxypyrene (1-OHP), deoxyribonucleic acid (DNA) adducts, and micronucleus frequency in both occupational and non-occupational populations of null and active GSTM1 carriers. We conducted a meta-analysis on 25 articles that met our strict inclusion criteria (11 studies on 1-OHP, 9 on DNA adducts, and 5 on the micronucleus frequency). In the case of occupationally exposed workers, micronucleus frequency was only significantly higher in the null GSTM1 carriers than in the active GSTM1 carriers. In the non-occupationally exposed general population, 1-OHP and micronucleus frequency were significantly higher in the null GSTM1 carriers. The results of Egger's test and funnel plot analysis indicated no significant publication bias. In conclusion, GSTM1 genotypes may affect the urinary 1-OHP in the non-occupationally exposed general population, and micronucleus frequency in both occupational workers and non-occupational population. Int J Occup Med Environ Health 2017;30(2):177-201.
journal_name
Int J Occup Med Environ Healthauthors
Li D,Wang B,Feng G,Xie M,Wang L,Gao Rdoi
10.13075/ijomeh.1896.01054subject
Has Abstractpub_date
2017-03-30 00:00:00pages
177-201issue
2eissn
1232-1087issn
1896-494Xpii
65310journal_volume
30pub_type
杂志文章,meta分析,评审abstract：OBJECTIVES:Sleep disorders can affect health and occupational performance of physicians as well as outcomes in patients. The purpose of this study was to assess the prevalence of excessive daytime sleepiness (EDS) measured by the Epworth Sleepiness Scale (ESS) among academic physicians at a tertiary academic medical ce...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.13075/ijomeh.1896.00367
更新日期：2015-01-01 00:00:00
abstract：:Morphine is an opiate alkaloid characterized by various clinical effects, among which the most prominent are its analgesic and psychoactive effects. It also has a prominent depressive effect on the respiratory and cardiovascular system. Because of its psychoactive effect, morphine is very addictive and often used as a...
journal_title：International journal of occupational medicine and environmental health
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doi：10.13075/ijomeh.1896.01629
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abstract：:The working environment is the special case of the non-natural environment created by man in which the increased production activity brings about the concentration of stimulators particularly aggressive to the human organism, such as chemical hazards, noise, vibration, extreme temperatures, and finally, intensified ps...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章,评审
doi：10.13075/ijomeh.1896.00243
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVES:Only a few studies have analyzed the health of self-employed workers. This cross-sectional study is the first to compare health status among craftsmen joiners and paid joiners. MATERIAL AND METHODS:Clinical and paraclinical data for self-employed craftsmen and employees were collected by occupational health...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.2478/s13382-014-0261-0
更新日期：2014-06-01 00:00:00
abstract：OBJECTIVES:The objectives of this study have been to: 1) describe and compare urban and rural injured worker populations in Alberta, Canada; 2) identify return-to-work outcomes in urban and rural populations; 3) examine the relationship between geographic location of residence and recovery from work-related musculoskel...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.13075/ijomeh.1896.00926
更新日期：2017-07-14 00:00:00
abstract：:In 'Hard' science, scientists correctly operate as the 'guardians of certainty', using hypothesis testing formulations and value judgements about error rates and time discounting that make classical inferential methods appropriate. But these methods can neither generate most of the inputs needed by decision makers in ...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章,评审
doi：
更新日期：2004-01-01 00:00:00
abstract：:Information protocols on the causes of acute poisoning exposures with chemicals in children up to 14 years old collected during 1990-95 at the National Poison Information Centre have been analyzed. Approximately 96% of intoxication were accidental, 44% of patients were poisoned with drugs, 22% with household products ...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:The 'Sendzimir' Steel Mill, Cracow, Poland, gives employment to approximately 17,000 workers. During the years 1994-98, 1396 compensation claims for diseases related to occupational hazards were registered. After a scrupulous investigation, 851 cases were certified as occupation-related diseases. Of this number, 481 c...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
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journal_title：International journal of occupational medicine and environmental health
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doi：10.13075/ijomeh.1896.01361
更新日期：2019-06-14 00:00:00
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journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.2478/s13382-011-0010-6
更新日期：2011-03-01 00:00:00
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journal_title：International journal of occupational medicine and environmental health
pub_type：
doi：10.13075/ijomeh.1896.01019
更新日期：2017-10-06 00:00:00
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journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
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journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
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journal_title：International journal of occupational medicine and environmental health
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doi：10.13075/ijomeh.1896.01264
更新日期：2018-10-23 00:00:00
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journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
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journal_title：International journal of occupational medicine and environmental health
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更新日期：2002-01-01 00:00:00
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journal_title：International journal of occupational medicine and environmental health
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doi：10.13075/ijomeh.1896.01073
更新日期：2017-10-06 00:00:00
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更新日期：2016-11-18 00:00:00
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journal_title：International journal of occupational medicine and environmental health
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更新日期：1995-01-01 00:00:00
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journal_title：International journal of occupational medicine and environmental health
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journal_title：International journal of occupational medicine and environmental health
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journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章,多中心研究
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更新日期：1995-01-01 00:00:00
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更新日期：2004-01-01 00:00:00
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更新日期：2019-11-15 00:00:00
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journal_title：International journal of occupational medicine and environmental health
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doi：
更新日期：2001-01-01 00:00:00
