Abstract：
INTRODUCTION:Few studies have addressed the primary characteristics of patients infected with hepatitis B virus (HBV) in the general population, especially those living in small- and medium-sized cities in Brazil. We aimed to determine the clinical, demographic, and epidemiologic characteristics of patients diagnosed with HBV who were followed up at an infectious diseases clinic of a public hospital in State of São Paulo, Brazil. METHODS:Medical records of patients aged >18 years and diagnosed with HBV infection between January 2000 and December 2013 were reviewed. RESULTS:Seventy-five patients were enrolled with male-female main infection-associated risk factors; 9 (12%) were co-infected with human immunodeficiency virus (HIV), 5 (6.7%) with hepatitis C virus (HCV), and 3 (4%) were co-infected with both HIV and HCV. Antiviral HBV therapy was applied in 21 (28%) patients and tenofovir monotherapy was the most prescribed medication. After approximately 2 years of antiviral treatment, the HBV-DNA viral load was undetectable in 12 (92.3%) patients and lower levels of alanine aminotransferase were found in these patients. CONCLUSIONS:Over a 13-year interval, very few individuals infected with HBV were identified, highlighting the barriers for caring for patients with HBV in developing countries. New measures need to be implemented to complement curative practices.
journal_name
Rev Soc Bras Med Tropjournal_title
Revista da Sociedade Brasileira de Medicina Tropicalauthors
Prestes-Carneiro LE,Vieira JT,Isaac LB,Portelinha Filho AMdoi
10.1590/0037-8682-0315-2015subject
Has Abstractpub_date
2016-02-01 00:00:00pages
24-8issue
1eissn
0037-8682issn
1678-9849pii
S0037-86822016000100024journal_volume
49pub_type
杂志文章abstract：:Chagas Disease is caused by Trypanosoma cruzi. This infection is endemic in the Americas region. Neurological Chagas reactivation is diagnosed through the visualization of the parasite in the cerebrospinal fluid, blood, or tissue samples. Herein, we report the visualization of trypomastigotes by direct microscopic obs...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type：
doi：10.1590/0037-8682-0326-2020
更新日期：2020-12-21 00:00:00
abstract：:Mucocutaneous leishmaniasis (MCL) is a chronic infection that can affect the skin and mucous membranes. We report a case of oral, nasopharyngeal, and penile lesions in a 35-year-old cocaine user. The patient presented with ulcerated lesions in 2014. Histopathologic analysis revealed amastigotes, and serological test r...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type：
doi：10.1590/0037-8682-0040-2020
更新日期：2020-06-22 00:00:00
abstract：:The first three months of 2002 witnessed a dengue epidemic in the State of Rio de Janeiro. At that time, health authorities encouraged community participation in the elimination of vector breeding sites. For this campaign, a great quantity of information about the disease was extensively publicized in order to guide t...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/s0037-86822004000400011
更新日期：2004-07-01 00:00:00
abstract：:Human accidental infection with Angiostrongylus costaricensis may result in abdominal disease of varied severity. Slugs from the Veronicellidae family are the main intermediate hosts for this parasitic nematode of rodents. Phyllocaulis variegatus, Phyllocaulis soleiformis and Phyllocaulis boraceiensis were experimenta...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/s0037-86821998000300006
更新日期：1998-05-01 00:00:00
abstract：INTRODUCTION:The concentration of dogs and cats in urban areas, associated with an ever-increasing wandering population of these animals, has an important epidemiological role in the soil contamination of public spaces and the spread of infections of several types of parasites. This study aimed to determine the frequen...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/s0037-86822011005000026
更新日期：2011-05-01 00:00:00
abstract：INTRODUCTION:In vitro bioassays were performed to access the larvicidal activity of crude extracts from the endophytic fungus Pestalotiopsis virgulata (Melanconiales, Amphisphaeriaceae) and the saprophytic fungus Pycnoporus sanguineus (Basidiomycetes, Polyporaceae) against the mosquitoes Aedes aegypti and Anopheles nun...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/0037-8682-0063-2013
更新日期：2013-07-01 00:00:00
abstract：:[This corrects the article doi: 10.1590/0037-8682-0243-2015] [This corrects the article doi: 10.1590/0037-8682-0454-2015]. ...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 已发布勘误
doi：10.1590/0037-8682-0366-2016
更新日期：2016-09-01 00:00:00
abstract：:Diagnosing cases of coronavirus disease (COVID-19) with only non-respiratory symptoms has been challenging. We reported the diagnosis of a child who tested positive for COVID-19 with abdominal pain/diarrhea and tracked his family cluster. One member of the family tested positive for COVID-19 on real-time reverse-trans...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/0037-8682-0494-2020
更新日期：2020-01-01 00:00:00
abstract：:This review has three objectives: a) To stimulate further research of this prevalent human infection b) to examine the progress of current diagnostic techniques and c) to emphasise the significance of the flagellate parasite Trypanosoma (Herpetosoma) rangeli in Chagas' Disease endemic areas of South and Central Americ...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章,评审
doi：10.1590/s0037-86821998000200007
更新日期：1998-03-01 00:00:00
abstract：:This study aimed to evaluate the second-generation OptiMal test for malaria diagnosis under various storage conditions. It detected all the positive samples, except for two Plasmodium malariae samples. Further research evaluating diverse environmental conditions are important for ICT test applicability in Brazilian ma...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/s0037-86822005000200015
更新日期：2005-03-01 00:00:00
abstract：:780 patients with recurrent conjunctival infections or persistent complaints of itching, burning pain, lacrimation and conjunctival hyperemia were subject to conjunctival smear examination for cytology and the presence of inclusion bodies. Two hundred and forty seven (31.7%) showed cytoplamic inclusions; 235 of them w...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/s0037-86821990000100006
更新日期：1990-01-01 00:00:00
abstract：:Previous evaluation of the genetic variability of four biogeographical populations of Lutzomyia whitmani from known foci of cutaneous leishmaniasis in Brazil demonstrated two main spatial clusters: Corte de Pedra-BA, Ilhéus-BA and Serra de Baturité-CE in the first cluster, and Martinho Campos-MG in the second. Further...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/s0037-86822004000200007
更新日期：2004-03-01 00:00:00
abstract：:The responses of Plasmodium falciparum to antimalarial drugs were evaluated through the in vitro test using blood sample collected from patients of 7 municipalities of the south of Pará State. Sixty nine microtests for chloroquine and mefloquine, 62 for amodiaquine and 61 for quinine were performed. The results showed...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/s0037-86821993000100002
更新日期：1993-01-01 00:00:00
abstract：:Four specimens of Triatoma vitticeps and one of Panstrongylus geniculatus were caught inside a home in the municipality of São Fidélis, Rio de Janeiro. One of the specimens of Triatoma vitticeps proved positive for infection with Trypanosoma cruzi. Two people living in that home (one adult and one adolescent) presente...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/s0037-86822008000400020
更新日期：2008-07-01 00:00:00
abstract：:This study aimed to determine the prevalence of HTLV-1 infection among remnant black quilombo communities in Central Brazil. A total of 1,837 individuals were evaluated, among whom nine were HTLV-1/2 seropositive according to ELISA. All of them were positive for HTLV-1 by means of Western blot and/or PCR, thus resulti...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/s0037-86822009000600009
更新日期：2009-11-01 00:00:00
abstract：INTRODUCTION:Previous studies have shown high residual risk of transfusing a blood donation contaminated by human immunodeficiency virus (HIV) or hepatitis C virus (HCV) in Brazil and motivated the development of a Brazilian platform for simultaneous detection of both viruses by nucleic acid amplification test (NAT) de...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/0037-8682-0133-2014
更新日期：2014-07-01 00:00:00
abstract：INTRODUCTION:This study aimed to evaluate the response to hepatitis B (HB) revaccination of healthcare workers (HCW) who are negative for antibodies to HB surface antigen (anti-HBs) after a complete vaccination series. METHODS:HCW whose anti-HBs test was performed > 90 days after a HB vaccination course were given a 4...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/s0037-86822012000500018
更新日期：2012-10-01 00:00:00
abstract：:This study evaluated the performance of single and combined laboratory parameters, B-lymphocyte percentages (%LB), T/B cell ratio and %CD8+HLA-DR+/CD8+, to differentiate asymptomatic cases (AS) from HAM/TSP patients (HT) within a population of HTLV-1 seropositive cases. Percentage indices demonstrated that each parame...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/s0037-86822007000100006
更新日期：2007-01-01 00:00:00
abstract：:Benznidazole, drug of choice for Chagas disease (CD), has been associated with a high incidence of adverse reactions that can become serious, necessitating discontinuation of the drug. We describe the case of a Bolivian patient living in Spain for 9 years, who, following treatment with benznidazole for CD in indetermi...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type：
doi：10.1590/0037-8682-0071-2016
更新日期：2017-01-01 00:00:00
abstract：INTRODUCTION:Evidence suggests that giardiasis is a zoonotic disease. The present work aimed to evaluate the genetic identity of Giardia duodenalis isolated from human and dog fecal samples from Belo Horizonte. METHODS:Human and dog fecal samples were cultured for isolation of G. duodenalis. To determine the genotype ...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/s0037-86822011000400021
更新日期：2011-07-01 00:00:00
abstract：:Were analyzed 648 serum samples from laboratory staff in Goiânia, Goiás aiming detection of three serological markers of HBV: HBsAg, anti-HBsAg and anti-HBcAg. The HBsAg and anti-HBcAg positive samples were also analyzed for HBeAg, anti-HBeAg and anti-HBcAgIgM markers. HBV infection rate of 24.1% was observed and, fro...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/s0037-86822005000200005
更新日期：2005-03-01 00:00:00
abstract：:This study presents the clinical and epidemiological aspects of children affected with dengue, in Manaus, AM, in 2006 and 2007. There were 482 The aim of this study was to present the clinical and epidemiological characteristics of children affected by dengue, in Manaus, State of Amazonas, in 2006 and 2007. Analysis w...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/s0037-86822009000100005
更新日期：2009-01-01 00:00:00
abstract：INTRODUCTION:Abdominal palpation and ultrasound findings among patients from an endemic area for schistosomiasis in Brazil who had been followed up for 27 years were compared. METHODS:In 2004, 411 patients from Brejo do Espírito Santo, in the State of Bahia, were selected for the present investigation after giving the...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/s0037-86822010000200005
更新日期：2010-03-01 00:00:00
abstract：:Fecal samples from 140 adult stray dogs of Greater São Paulo (São Paulo State, Brazil) were examined for Cyclospora sp oocysts. No cases of infection by this coccidium were detected. ...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/s0037-86822001000600017
更新日期：2001-11-01 00:00:00
abstract：INTRODUCTION:The aim of this study was to evaluate some virulence factors in Candida albicans isolates from patients with onychomycosis and determine the correlation between these factors and the antifungal resistance profile. METHODS:Seventy species of C. albicans were confirmed using polymerase chain reaction amplif...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/0037-8682-0214-2019
更新日期：2020-02-07 00:00:00
abstract：INTRODUCTION:Professionals who handle rodents in the field and in the laboratory are at risk of infection by the microorganis mharbored by these animals. METHODS:Serum samples from professionals involved in rodent and Yersinia pestis handling in field or laboratory work were analyzed to determine hantavirus and plague...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/0037-8682-1394-2013
更新日期：2013-07-01 00:00:00
abstract：INTRODUCTION:Chagas disease is caused by Trypanosoma cruzi and treated with benznidazole (BNZ). This drug has the troublesome features of presenting partial effectiveness and high toxicity ranging from hypersensitivity reactions to medullary aplasia. The objective here was to describe and evaluate the occurrence of adv...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/s0037-86822010000200015
更新日期：2010-03-01 00:00:00
abstract：:Mansonic schistosomiasis remains a medical-social issue in Northeastern Brazil. In children, surgical treatment includes splenectomy and spleen autoimplantation. This procedure reduces post-splenectomy sepsis. The aim of this study was to analyze the phagocyte rate and the cellular viability of monocytes in patients w...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/s0037-86822006000500004
更新日期：2006-09-01 00:00:00
abstract：:Over the last years there has been considerable progress in the treatment of chronic hepatitis B. Five drugs are now approved for the treatment of this virosis: interferon alpha, lamivudine, adefovir, entecavir and telbivudine. Interferons (conventional or PEG) were the first medicine used in the treatment of hepatiti...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章,评审
doi：10.1590/s0037-86822007000400016
更新日期：2007-07-01 00:00:00
abstract：INTRODUCTION:The diagnostic accuracy of Xpert MTB/RIF (Xpert) in pulmonary tuberculosis (PTB) in children is lower than in adults. In Brazil, the diagnosis of PTB is based on a diagnostic score system (DSS). This study aims to study the role of Xpert in children and adolescents with PTB symptoms. METHODS:cross-section...
journal_title：Revista da Sociedade Brasileira de Medicina Tropical
pub_type： 杂志文章
doi：10.1590/0037-8682-0205-2020
更新日期：2020-09-25 00:00:00
