Adverse systemic reaction to benznidazole.

Abstract:

:Benznidazole, drug of choice for Chagas disease (CD), has been associated with a high incidence of adverse reactions that can become serious, necessitating discontinuation of the drug. We describe the case of a Bolivian patient living in Spain for 9 years, who, following treatment with benznidazole for CD in indeterminate chronic phase, presented with fever, skin lesions, digestive symptoms, general malaise, and laboratory abnormalities. After the discontinuation of benznidazole and, the intake of antihistamines and systemic corticosteroids, the patient presented a complete resolution of the symptoms. Optimization of dose strategies and development of more effective, and better-tolerated drugs is advisable.

journal_name

Rev Soc Bras Med Trop

authors

Coronel MV,Frutos LO,Muñoz EC,Valle DK,Rojas DH

doi

10.1590/0037-8682-0071-2016

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

145-147

issue

1

eissn

0037-8682

issn

1678-9849

pii

S0037-86822017000100145

journal_volume

50

pub_type

  • [Soil contamination by eggs of soil-transmitted helminths with zoonotic potential in the town of Fernandópolis, State of São Paulo, Brazil, between 2007 and 2008].

    abstract:INTRODUCTION:The concentration of dogs and cats in urban areas, associated with an ever-increasing wandering population of these animals, has an important epidemiological role in the soil contamination of public spaces and the spread of infections of several types of parasites. This study aimed to determine the frequen...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822011005000026

    authors: Cassenote AJ,Pinto Neto JM,Lima-Catelani AR,Ferreira AW

    更新日期:2011-05-01 00:00:00

  • [Epidemiological and clinical aspects of snake bites in the municipalities of the state of Amazonas, Brazil].

    abstract::In the State of Amazonas, accidents with snakes are a public health problem. For this reasons, the objective of this work was to carry out a descriptive study of the snake accidents attended in the health units of 34 municipalities, one district and two border platoons in the State of Amazonas. The characteristics mos...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:

    authors: Campos Borges C,Sadahiro M,dos Santos MC

    更新日期:1999-11-01 00:00:00

  • American cutaneous leishmaniasis in a northeast Brazilian city: clinical and epidemiological features.

    abstract:INTRODUCTION:This study characterized the clinico-epidemiological profile of American cutaneous leishmaniasis (ACL) cases in Barbalha, Ceará State, Brazil. METHODS:Medical records of 363 patients visiting Federal University of Cariri between 2009 and 2014 were analyzed. RESULTS:ACL was more prevalent in men with low ...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0504-2017

    authors: Grangeiro Júnior CRP,Pimentel JVC,Teixeira Júnior AG,Jesus AF,Galvão TCF,Souza LAA,Gadelha MDSV,Damasceno KS,Rolim Neto ML,Lima MAP,Nascimento VBD,Silva CGLD

    更新日期:2018-11-01 00:00:00

  • Clinical, demographic and epidemiological characteristics of patients with hepatitis B followed at a university hospital in southeastern Brazil: predominance of HBeAg negative cases.

    abstract:INTRODUCTION:Hepatitis B is common in Brazil, although there are regional differences regarding the degree of endemicity, the most frequent forms of transmission and the presence of different evolutive stages of chronic disease. The present study aimed to determine the clinical, demographic and epidemiological characte...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822011000100004

    authors: Chachá SG,Ferreira Sda C,Costa TV,Almeida Filho LC,Villanova MG,Souza FF,Teixeira AC,Figueiredo JF,Zucoloto S,Ramalho LN,Passos AD,Martinelli Ade L

    更新日期:2011-01-01 00:00:00

  • Bacterial meningitis and living conditions.

    abstract:INTRODUCTION:Bacterial meningitis has great social relevance due to its ability to produce sequelae and cause death. It is most frequently found in developing countries, especially among children. Meningococcal meningitis occurs at a high frequency in populations with poor living conditions. This study describes the te...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822012000300009

    authors: Souza SF,Costa Mda C,Paim JS,Natividade MS,Pereira SM,Andrade AM,Teixeira MG

    更新日期:2012-06-01 00:00:00

  • [The prevalence of intestinal parasitoses among the users of the Health Center of Sousas District, Campinas, São Paulo (1986-1990)].

    abstract::The prevalence of intestinal parasites was carried on users of the Health Center of Sousas District, Campinas, SP (1986-1990). From 770 observed medical records we verify 114 positive cases (14.8%) for protozoa, helminths and commensals. Ascaris lumbricoides (48.2%), Giardia lamblia (30.7%), Trichuris trichiura (18.4%...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86821992000300005

    authors: Gioia I

    更新日期:1992-07-01 00:00:00

  • Ectopic schistosomiasis: description of five cases involving skin, one ovarian case and one adrenal case.

    abstract::Seven cases of patients with ectopic schistosomiasis from the State of Sergipe, Brazil, are presented (five involving skin, one ovarian and one adrenal). Data were collected from surveying the clinical records and anatomopathological reports in the files of the dermatology and pathology clinics of the University Hospi...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822008000600021

    authors: Poderoso WL,Santana WB,Costa EF,Cipolotti R,Fakhouri R

    更新日期:2008-11-01 00:00:00

  • Ecological aspects of the sandfly fauna (Diptera, Psychodidae) in an American cutaneous leishmaniasis endemic area under the influence of hydroelectric plants in Paranapanema river, State of Paraná, Brazil.

    abstract:INTRODUCTION:An epidemiological study was undertaken to identify determinant factors in the occurrence of American cutaneous leishmaniasis in areas under the influence of hydroelectric plants in Paranapanema river, State of Paraná, Brazil. The ecological aspects of the phlebotomine fauna were investigated. METHODS:San...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822012000400003

    authors: Cruz MF,Galati EA,Cruz CF

    更新日期:2012-07-01 00:00:00

  • [Use of new tools for controlling triatomines in different entomologic situations in the American continent].

    abstract::The field results of new tools for triatomine control developed under the sponsorship of WHO/TDR are reported: a) A slow-release "paint" containing malathion; b) fumigant cans containing cypermethrin and DDVP, and c) sensor boxes for the detection of triatomine infestations. Field assays were performed in Chile, Hondu...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86821997000100008

    authors: Oliveira Filho AM

    更新日期:1997-01-01 00:00:00

  • [Influence of specific treatment of intestinal parasites and schistosomiasis on prevalence in students in Barra de Santo Antônio, AL].

    abstract::From a total of 1,020 students examined, 983 (92%) showed positive results for at least one species of parasite. Six months after treatment, a sample of 383 students (37.5%) was reevaluated and 347 (90.6%) presented positive results. There was no significant change in prevalence before and after treatment, although th...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822003000500015

    authors: Fontes G,Oliveira KK,Oliveira AK,da Rocha EM

    更新日期:2003-09-01 00:00:00

  • Favorable responses to treatment with 5 mg Sbv/kg/day meglumine antimoniate in patients with American tegumentary leishmaniasis acquired in different Brazilian regions.

    abstract:INTRODUCTION:Favorable responses in American tegumentary leishmaniasis (ATL) patients to treatment with 5 mg Sbv/kg/day meglumine antimoniate (MA) has been reported in Rio de Janeiro, but little is known regarding the therapeutic response to low doses in patients from other locations. METHODS:A retrospective review of...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0464-2017

    authors: Cataldo JI,Conceição-Silva F,Antônio LF,Schubach AO,Marzochi MCA,Valete-Rosalino CM,Pimentel MIF,Lyra MR,Oliveira RVC,Barros JHDS,Pacheco RDS,Madeira MF

    更新日期:2018-11-01 00:00:00

  • Simultaneous occurrence of pulmonary tuberculosis and carcinomatous lymphangitis.

    abstract::Tuberculosis is an important cause of mortality due to its high prevalence, considering that one third of the worlds population is infected with the tuberculosis bacillus. We report the first case of carcinomatous lymphangitis associated with active pulmonary tuberculosis. Carcinomatous lymphangitis is a rare event th...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822007000100016

    authors: Tuon FF,Miyaji KT,de Vidal PM,da Silva LF,Kono A,Franca FO

    更新日期:2007-01-01 00:00:00

  • [Physico-chemical characteristics of meglumine antimoniate in different storage conditions].

    abstract::During the period October 1992 to July 1995 we measured the osmolarity and pH of ampoules of meglumine antimoniate (glucantime) from lot 9206L-004 (manufactured by Rhodia Farma Ltd, of São Paulo, SP, Brazil) maintained in three temperature conditions namely 4 degrees C, 37 degrees C and ambiental. Although we observed...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86821996000500009

    authors: Romero GA,de Oliveira MR,Correia D,Marsden PD

    更新日期:1996-09-01 00:00:00

  • [Comparison between the epidemiology of accidents and the clinical features of envenoming by snakes of the genus Bothrops, among elderly and non-elderly adults].

    abstract::This study had the aim of ascertaining epidemiological and clinical differences in envenoming caused by Bothrops spp between elderly adults (>60 years) and non-elderly adults (20 to 59 years). The data were obtained from 1,930 medical records of patients attended at the Butantan Institute between 1981 and 1992. The gr...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822008000100009

    authors: Ribeiro LA,Gadia R,Jorge MT

    更新日期:2008-01-01 00:00:00

  • A list of mosquito species of the Brazilian State of Pernambuco, including the first report of Haemagogus janthinomys (Diptera: Culicidae), yellow fever vector and 14 other species (Diptera: Culicidae).

    abstract:INTRODUCTION:Besides mosquito species adapted to urban environments (Culex quinquefasciatus, Aedes aegypti and Aedes albopictus), only 15 species of Anopheles had been recorded in the State of Pernambuco. METHODS:Human-landing mosquitoes were collected in Dois Irmãos Park, in Recife. RESULTS:The first report for the ...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822010000400024

    authors: Aragão NC,Müller GA,Balbino VQ,Costa Junior CR,Figueirêdo Júnior CS,Alencar J,Marcondes CB

    更新日期:2010-07-01 00:00:00

  • [Prevention concerning the different alternative routes for transmission of Trypanosoma cruzi in Brazil].

    abstract::Vectorial, transfusion and congenital are considered the main transmission mechanisms in human Chagas disease. Alternative mechanisms are accidental, oral and by organ transplantation. Other hypothetic mechanisms could be by other vectors, sexual, criminal and by means of marsupial anal secretions. The present accorde...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822011000800011

    authors: Dias JC,Amato Neto V

    更新日期:2011-01-01 00:00:00

  • [Natural infection with Leishmania infantum chagasi in Lutzomyia (Lutzomyia) longipalpis (Diptera: Psychodidae) sandflies captured in the municipality of Janaúba, State of Minas Gerais, Brazil].

    abstract:INTRODUCTION:Visceral leishmaniasis has been notified in nearly all states of Brazil, and particularly in the north of Minas Gerais, where the disease is endemic. The aim of this study was to detect natural infection of Lutzomyia longipalpis and, through the PCR/RFLP technique, identify Leishmania species found in sand...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822011000100014

    authors: Michalsky EM,Guedes Kde S,Lara e Silva Fde O,França-Silva JC,Dias CL,Barata RA,Dias ES

    更新日期:2011-01-01 00:00:00

  • Potential for entomopathogenic fungi to control Triatoma dimidiata (Hemiptera: Reduviidae), a vector of Chagas disease in Mexico.

    abstract:INTRODUCTION:The use of entomopathogenic fungi to control disease vectors has become relevant because traditional chemical control methods have caused damage to the environment and led to the development of resistance among vectors. Thus, this study assessed the pathogenicity of entomopathogenic fungi in Triatoma dimid...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0193-2014

    authors: Vázquez-Martínez MG,Cirerol-Cruz BE,Torres-Estrada JL,López MH

    更新日期:2014-11-01 00:00:00

  • Hepatitis B virus surface antigen (HBsAg) and antibody (anti-HBs) forming immune complexes in fulminant hepatitis.

    abstract::This paper reports an unusual pattern of serological HBV markers and the presence of HBsAg/anti-HBs immune complexes in serum samples from two patients with fulminant hepatitis from the Brazilian Western Amazon Basin. The diagnosis was made by both serologic tests and demonstration of antigen/antibody complexes by tra...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86821999000300012

    authors: Soares MC,Bensabath G,Cartágenes PR,Alves MM,Silveira FA,Linhares AC

    更新日期:1999-05-01 00:00:00

  • Incidence of tuberculous meningitis in the State of Santa Catarina, Brazil.

    abstract:INTRODUCTION:The aim of this study was to estimate the incidence of tuberculous meningitis in the State of Santa Catarina (SC), Brazil, during the period from 2001 to 2010. METHODS:Ecological, temporal, and descriptive methods were employed using data obtained from the Information System on Disease Notification (Siste...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0122-2014

    authors: Souza CH,Yamane A,Pandini JC,Ceretta LB,Ferraz F,da Luz GD,Simões PW

    更新日期:2014-07-01 00:00:00

  • Changes in the prevalence, incidence and residual risk for HIV and hepatitis C virus in Southern Brazilian blood donors since the implementation of NAT screening.

    abstract:INTRODUCTION:Previous studies have shown high residual risk of transfusing a blood donation contaminated by human immunodeficiency virus (HIV) or hepatitis C virus (HCV) in Brazil and motivated the development of a Brazilian platform for simultaneous detection of both viruses by nucleic acid amplification test (NAT) de...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0133-2014

    authors: Kupek E,Petry A

    更新日期:2014-07-01 00:00:00

  • Bone tuberculosis: a case report on child.

    abstract::The authors report a case of a 12-year-old child with a complaint of pain and deformity in the lower thoracic region that had lasted for two years. Clinical, epidemiological and laboratory characteristics associated with images of apparent damage in the T9-T10 and T11-T12 vertebrae taken by radiography of the thoracic...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0010-2012

    authors: Santos FC,Nascimento AL,Lira LA,Lima JF,Montenegro Rde A,Montenegro LM,Schindler HC

    更新日期:2013-03-01 00:00:00

  • Molecular identification of the agent of Q fever - Coxiella burnetii - in domestic animals in State of Rio de Janeiro, Brazil.

    abstract:INTRODUCTION:Over the last recent years, the number of Q fever cases have has increased throughout the world. An epidemiological investigation was performed in the area in which the first molecular documentation of Q fever in Brazil was previously reported. METHODS:Indirect immunofluorescence assay (IFA) and PCR of Co...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0076-2013

    authors: Mares-Guia MA,Rozental T,Guterres A,Gomes R,Almeida DN,Moreira NS,Barreira JD,Favacho AR,Santana AL,Lemos ER

    更新日期:2014-03-01 00:00:00

  • [Low adherence and high cost as factors in the failure of the use of insecticide-impregnated mosquito bed nets in the control of malaria in the Brazilian Amazon].

    abstract::In 1992 during a trial with deltamethrin-impregnated bed nets conducted in Porto Murtinho, municipality of Costa Marques, Rondônia, in the Brazilian Amazon, we investigated community compliance and the economic aspects capable of reducing the impact of this intervention on malaria morbidity. Impregnated bed nets were ...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:

    authors: Santos JB

    更新日期:1999-07-01 00:00:00

  • Experimental visceral leishmaniasis in high and low antibody-producer mice (selection IV-A).

    abstract::Leishmaniasis is a typical parasite infection whose protective immunity depends on macrophage activation. Susceptibility to Leishmania donovani infection was compared in H (high antibody responder) and L (low antibody responder) mice from selection IV-A. H mice infected intravenously with 10(7) amastigotes of L. donov...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86821999000300002

    authors: Fechio CJ,Soares AM,de Oliveira SL,Sartori A

    更新日期:1999-05-01 00:00:00

  • [Aspects of the ecology and behaviour of phlebotomines in endemic area for visceral leishmaniasis in State of Minas Gerais].

    abstract::Studies on the behavioral and feeding habits of some species of phlebotominae sand flies have contributed to the comprehension of the epidemiology of leishmaniasis. In the present work, systematic captures were performed monthly in the municipality of Porteirinha (MG) using 28 light traps (CDC) from January to Decembe...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822005000500012

    authors: Barata RA,França-Silva JC,Mayrink W,Silva JC,Prata A,Lorosa ES,Fiúza JA,Gonçalves CM,Paula KM,Dias ES

    更新日期:2005-09-01 00:00:00

  • Outbreak of neonatal infection by an endemic clone of Serratia marcescens.

    abstract:INTRODUCTION:The outbreak occurred between February and June 2006 and included identification of the cases, analysis of medical records, cultures from environmental sources, resistance analyses and genotyping profile of Serratia marcescens. METHODS:The cultures were composed of 13 blood isolates, 17 rectal and hand sw...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822011000100024

    authors: Lima KV,Carvalho RG,Carneiro IC,Lima JL,Sousa Cde O,Loureiro EC,Sá LL,Bastos FC

    更新日期:2011-01-01 00:00:00

  • Comparative performance of four malaria rapid diagnostic tests, Vikia Malaria Pf/Pan, Meriline-Meriscreen Pf/Pv/Pan, Right Sign Malaria Pf/Pan, and Right Sign Malaria Pf, among febrile patients in Gabon.

    abstract:INTRODUCTION:Rapid diagnostic tests (RDTs) are selected based on their performances. Here, we compared the diagnostic performance of different malaria RDTs. METHODS:Febrile patients were tested for malaria using Vikia Malaria Pf/Pan, Meriline-Meriscreen Pf/Pv/Pan, Right Sign Malaria Pf/Pan, and Right Sign Malaria Pf R...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0274-2019

    authors: Ditombi BCM,Minko JI,Tsamba RP,Ngomo JMN,Nymane T,Ognagosso FBB,M'bondoukwe NP,Mawili-Mboumba DP,Akotet MKB

    更新日期:2020-06-22 00:00:00

  • Post-splenectomy infections in chronic schistosomiasis as a consequence of bacterial translocation.

    abstract:INTRODUCTION:Bacterial translocation is the invasion of indigenous intestinal bacteria through the gut mucosa to normally sterile tissues and internal organs. Schistosomiasis may cause alterations in the immune system and damage to the intestines, portal system and mesenteric lymph nodes. This study investigated bacter...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0042-2015

    authors: Lima Kde M,Negro-Dellacqua M,Dos Santos VE,de Castro CM

    更新日期:2015-05-01 00:00:00

  • [American cutaneous leishmaniasis: phlebotomine transmission area in the Municipality of Uberlândia, MG].

    abstract::From May 2000 to January 2001 four, 15 hour-long collections of phlebotomine were done to the insect monitoring. The collection was done in an area of infection of American cutaneous leishmaniasis in the basin of the Araguari River in the municipality of Uberlandia (MG). The first collection was made in May (a cold, d...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822005000100005

    authors: Lemos JC,Lima Sdo C

    更新日期:2005-01-01 00:00:00