Abstract:
INTRODUCTION:The aim of this study was to evaluate some virulence factors in Candida albicans isolates from patients with onychomycosis and determine the correlation between these factors and the antifungal resistance profile. METHODS:Seventy species of C. albicans were confirmed using polymerase chain reaction amplification of the HWP1 gene. According to the Clinical & Laboratory Standards Institute guidelines, the susceptibility profile of four antifungal agents was investigated, and the production of aspartyl protease, phospholipase, haemolysin, and biofilm was determined. The correlation between these profiles was also investigated. RESULTS:The isolates indicated different levels of resistance and production of virulence factors. Significant correlations were observed between the minimum inhibitory concentration (MIC) of fluconazole/itraconazole and biofilm production, between phospholipase production and fluconazole/itraconazole MIC, and between fluconazole MIC and hemolytic activity in C. albicans isolates. The results also showed significant correlations between phospholipase activity and biofilm production. CONCLUSIONS:Our findings will contribute to a better understanding of the pathogenesis of C. albicans and characterize the relationship between virulence factors and antifungal resistance, which may suggest new therapeutic strategies considering the possible involvement of the virulence mechanism in the effectiveness of treatment.
journal_name
Rev Soc Bras Med Tropjournal_title
Revista da Sociedade Brasileira de Medicina Tropicalauthors
Mohammadi F,Ghasemi Z,Familsatarian B,Salehi E,Sharifynia S,Barikani A,Mirzadeh M,Hosseini MAdoi
10.1590/0037-8682-0214-2019subject
Has Abstractpub_date
2020-02-07 00:00:00pages
e20190214eissn
0037-8682issn
1678-9849pii
S0037-86822020000100302journal_volume
53pub_type
杂志文章abstract:INTRODUCTION:Besides mosquito species adapted to urban environments (Culex quinquefasciatus, Aedes aegypti and Aedes albopictus), only 15 species of Anopheles had been recorded in the State of Pernambuco. METHODS:Human-landing mosquitoes were collected in Dois Irmãos Park, in Recife. RESULTS:The first report for the ...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86822010000400024
更新日期:2010-07-01 00:00:00
abstract:INTRODUCTION:Rabies is an acute zoonotic disease, caused by a rhabdovirus that can affect all mammals, and is commonly transmitted by the bite of a rabid animal. The definitive diagnosis is laboratorial, by the Fluorescent Antibody Test (FAT) as a quick test and Mouse Inoculation Test (MIT) as a confirmatory test (gold...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/0037-8682-0303-2017
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION:The Global Programme to Eliminate Lymphatic Filariasis was launched with the goal of eliminating this disease via the annual mass drug administration (MDA) of a single dose of antifilarial drugs. Adverse drug reactions following MDA are a major factor of poor treatment adherence in several countries. This ...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86822012000600017
更新日期:2012-12-01 00:00:00
abstract:INTRODUCTION:Strongyloides venezuelensis has been used as a model for studying human strongyloidosis. METHODS:This study aimed to compare the ability of predatory nematophagous fungi Duddingtonia flagrans (AC001), Arthrobotrys robusta (I-31) and Monacrosporium sinense (SF53) and on infective larvae (L3) of Strongyloid...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86822011000300026
更新日期:2011-05-01 00:00:00
abstract:INTRODUCTION:Hantavirus cardiopulmonary syndrome (HCPS) is rare in Northeastern Brazil. METHODS:Prospective surveillance was conducted over a two-year period in Alagoas State, Northeastern Brazil. The prevalence of anti-hantavirus N-antigen IgM and IgG in human serum samples was determined by enzyme-linked immunosorbe...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/0037-8682-0117-2017
更新日期:2017-11-01 00:00:00
abstract::[This corrects the article doi: 10.1590/0037-8682-0243-2015] [This corrects the article doi: 10.1590/0037-8682-0454-2015]. ...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 已发布勘误
doi:10.1590/0037-8682-0366-2016
更新日期:2016-09-01 00:00:00
abstract::Cryptococcus neoformans is an encapsulated yeast agent of human and animal cryptococcosis. The variety neoformans is an important cause of mortality in AIDS-patients throughout the world. It has already been isolated worldwide from different environmental sources, including avian habitats. However, in spite of the occ...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86822002000600008
更新日期:2002-11-01 00:00:00
abstract::The growth capacity at 39 degrees C and 42 degrees C, production of hydrolytic enzymes and hemolytic activity of 21 clinical and reference strains of seven species of Candida spp were evaluated in vitro.Candida dubliniensis and Candida krusei demonstrated lower virulence potential and Candida albicans higher potential...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86822009000200029
更新日期:2009-03-01 00:00:00
abstract::Introduction This study was conducted in Brazil and Colombia,where dengue is endemic and vector control programs use chemical insecticides. Methods We identified knowledge, attitudes, and practices about dengue and determined the infestation levels of Aedes aegypti in one Brazilian and four Colombian communities. Resu...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/0037-8682-0048-2014
更新日期:2014-11-01 00:00:00
abstract::Aeromonas spp is recognized as pathogenic to humans after consumption of contaminated water and food. In the present investigation, 2,323 rectal swab samples from newborns hospitalized in Rio de Janeiro were evaluated with a view to isolating Aeromonas. The samples were collected and sent to the national reference lab...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86822008000200009
更新日期:2008-03-01 00:00:00
abstract::780 patients with recurrent conjunctival infections or persistent complaints of itching, burning pain, lacrimation and conjunctival hyperemia were subject to conjunctival smear examination for cytology and the presence of inclusion bodies. Two hundred and forty seven (31.7%) showed cytoplamic inclusions; 235 of them w...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86821990000100006
更新日期:1990-01-01 00:00:00
abstract::In this study, the larvicidal activity of dried leaf extracts from Pinus caribaea Morelet against Aedes aegypti was evaluated for the first time. Pinus caribaea extracts were obtained by macerating dried leaves in alkaline hydroethanol, ethanol and acetone solutions followed by evaporation under reduced pressure. The ...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86822009000400003
更新日期:2009-07-01 00:00:00
abstract::The distribution of the most frequent enteroparasites in the population of Assis, State of São Paulo, was studied from 1990 to 1992. A total of 18,366 medical examinations from six sanitary care centers in the neighbourhoods of Marialves, Progresso, city center, Xavier, Fiúza and Bonfim were analyzed. The general prev...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86821999000500013
更新日期:1999-09-01 00:00:00
abstract::Angiostrongylus costaricensisis is an intra-arterial nematode of rodents. Man may become accidentally infected through ingestion of contaminated food or water. Our objective was to describe the parasite structures recognized by human antibodies in serum samples from acute and convalescent phases of abdominal angiostro...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86822003000400003
更新日期:2003-07-01 00:00:00
abstract::Interaction between clinical infection, vector, and population serotype immunity defines dengue epidemic risk. An endemic-sporadic epidemiological situation is an acceptable control target in metropolitan regions deficient in urban upgrading, sanitation, and health agents' access to residences, besides low residual po...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86822004000500009
更新日期:2004-09-01 00:00:00
abstract::In order to study certain epidemiological features of multidrug-resistant tuberculosis (MDR-TB) carriers and their influence on the control and treatment, a group of patients was evaluated over a four-year period, selected by: Mycobacterium tuberculosis isolation from sputum; resistance to Rifampin, Isoniazid and one ...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:INTRODUCTION:Professionals who handle rodents in the field and in the laboratory are at risk of infection by the microorganis mharbored by these animals. METHODS:Serum samples from professionals involved in rodent and Yersinia pestis handling in field or laboratory work were analyzed to determine hantavirus and plague...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/0037-8682-1394-2013
更新日期:2013-07-01 00:00:00
abstract:INTRODUCTION:The aim of this study was to detect the prevalence of the extended-spectrum beta-lactamase (ESBL)-encoding CTX-M gene in Escherichia coliisolates. METHODS:Phenotypic screening of 376 E. coli isolates for ESBL was conducted using disk diffusion. ESBL-producing isolates were tested using PCR and specific pr...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/0037-8682-0315-2014
更新日期:2015-07-01 00:00:00
abstract::As a first measure of Chagas' disease control in Brazil with chemical elimination of the most important vector of the disease, Triatoma infestans was removed. Attention is now being paid to Triatoma sordida and Panstrongylus megistus. That species can eventually be found inside houses, as happened with the specimens w...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86821997000400010
更新日期:1997-07-01 00:00:00
abstract::Dengue infection has not been routinely investigated among pregnant women and parturients with acute febrile syndrome in endemic settings. Here, we report two cases of dengue fever detected at the time of delivery in parturients enrolled in a cohort prospective study conducted in a hospital in Recife, Brazil. The part...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type:
doi:10.1590/0037-8682-0306-2015
更新日期:2016-05-01 00:00:00
abstract::By morphological and morphometric analyses of serial sections the occurrence of T. cruzi nests in the central vein and in the parenchyma of adrenal glands, in the left ventricular wall and in the inferior vena cava wall in chronic Chagasic patients was studied. Of 36 cases 50% showed parasites in the adrenal central v...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86821991000200002
更新日期:1991-04-01 00:00:00
abstract::The production of phospholipase and proteinase exoenzymes was evaluated in seventy nine samples of Candida isolated from the oral cavity of patients with oral lesions characteristic of candidosis and from individuals presenting a clinically normal mouth, attended at the University of Dentistry of Ribeirão Preto USP. A...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86822000000500005
更新日期:2000-09-01 00:00:00
abstract::This study aimed to describe the epidemiology and spread of visceral leishmaniasis in the municipality of Várzea Grande, State of Mato Grosso, Brazil, between 1998 and 2007. Forty-eight human cases were reported, with an incidence rate of up to 11.7 per 100,000 inhabitants, particularly among children and adolescents ...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86822009000500005
更新日期:2009-09-01 00:00:00
abstract::This study sought for evidence of previous CMV infection in patients of a general hospital serving the low income population of Rio de Janeiro. An enzyme immunoassay was used to detect anti-CMV antibodies in 713 typical hospital patients classified into eight different groups. Positive tests were found in 87% of pregn...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86821995000200003
更新日期:1995-04-01 00:00:00
abstract:INTRODUCTION:Leptospirosis is caused by a bacterium of the genus Leptospira. This study aimed at investigating the seroprevalence of and risk factors for leptospirosis in humans in Manaus, State of Amazonas. METHODS:Interviews were performed, and 1,000 blood serum samples were examined using a microscopic agglutinatio...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/0037-8682-0115-2016
更新日期:2016-09-01 00:00:00
abstract:INTRODUCTION:This study confirmed the absence of natural infection with Xenotropic murine leukemia virus-related virus (XMRV) or XMRV-related disease in human populations of the Brazilian Amazon basin. We demonstrated that 803 individuals of both sexes, who were residents of Belem in the Brazilian State of Pará, were n...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/0037-8682-0075-2014
更新日期:2014-05-01 00:00:00
abstract::An epidemiological survey was carried out in 3,344 people of an urban town in Lagamar, Minas Gerais, Brazil--during 1992-1993, to evaluate the main risk factors related to taeniasis and cysticercosis. A total number of 875 (78.9%) houses were visited and 1080 (32.3%) subjects were clinically examined. Poor sanitary co...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86821998000100009
更新日期:1998-01-01 00:00:00
abstract:INTRODUCTION:Since women are frequently the minority among blood donors worldwide, studies evaluating this population usually reflect male features. We assessed the features of female blood donors with positive serology for HBV and compared them with those of men.METHODS The study comprised consecutive blood donors ref...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/0037-8682-0157-2015
更新日期:2015-09-01 00:00:00
abstract:INTRODUCTION:A decline in hepatitis D virus (HDV) occurrence was described in Europe and Asia. We estimated HDV prevalence in the Brazilian Amazon following hepatitis B vaccination. METHODS:This is a cross-sectional survey of HDV measured by total antibodies to HDV (anti-HD T). RESULTS:HDV prevalence was 41.9% whitin...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86822012000600007
更新日期:2012-12-01 00:00:00
abstract:INTRODUCTION:Visceral leishmaniasis has been notified in nearly all states of Brazil, and particularly in the north of Minas Gerais, where the disease is endemic. The aim of this study was to detect natural infection of Lutzomyia longipalpis and, through the PCR/RFLP technique, identify Leishmania species found in sand...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86822011000100014
更新日期:2011-01-01 00:00:00