Experience of splenectomy and cholecystectomy in children with chronic haemolytic anaemia.

Abstract:

:Since 1973, 419 children (233 boys, 186 girls) with chronic haemolytic anaemia (mean age, 10.2 +/- 3.5 years) have been splenectomised. Fifty-three (12.6%) have also been cholecystectomised because of cholelithiasis. Between 1973 and 1982, cholecystectomy and splenectomy were performed at the same time in symptomatic patients. Later, between 1983 and 1987, cholecystectomy was also performed in clinically asymptomatic patients with positive sonographic findings. In the first period, 11 thalassaemic patients (45.8%) were cholecystectomised a short period after splenectomy (in two cases, only 2 and 3 weeks later). Between 1983 and 1987, when asymptomatic patients with cholelithiasis were screened by sonography, simultaneous cholecystectomy and splenectomy were performed in 13.6% of the patients with thalassaemia, in 41% of the patients with sickle cell or microdrepanocytic disease, and in 22.2% of the patients with spherocytosis. As there is a high incidence of asymptomatic cholelithiasis and hypersplenism in patients with chronic haemolytic anaemia, screening for gallstones should precede splenectomy. Simultaneous cholecystectomy should be performed in patients with cholelithiasis.

journal_name

J Pediatr Surg

authors

Pappis CH,Galanakis S,Moussatos G,Keramidas D,Kattamis C

doi

10.1016/s0022-3468(89)80502-0

subject

Has Abstract

pub_date

1989-06-01 00:00:00

pages

543-6

issue

6

eissn

0022-3468

issn

1531-5037

pii

S0022346889002320

journal_volume

24

pub_type

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