Abstract:
:Metagenomic next-generation sequencing (mNGS) of samples from 15 patients with documented Zika virus (ZIKV) infection in Bahia, Brazil, from April 2015 to January 2016 identified coinfections with chikungunya virus (CHIKV) in 2 of 15 ZIKV-positive cases by PCR (13.3%). While generally nonspecific, the clinical presentation corresponding to these two CHIKV/ZIKV coinfections reflected infection by the virus present at a higher titer. Aside from CHIKV and ZIKV, coinfections of other viral pathogens were not detected. The mNGS approach is promising for differential diagnosis of acute febrile illness and identification of coinfections, although targeted arbovirus screening may be sufficient in the current ZIKV outbreak setting.
journal_name
J Clin Microbioljournal_title
Journal of clinical microbiologyauthors
Sardi SI,Somasekar S,Naccache SN,Bandeira AC,Tauro LB,Campos GS,Chiu CYdoi
10.1128/JCM.00877-16subject
Has Abstractpub_date
2016-09-01 00:00:00pages
2348-53issue
9eissn
0095-1137issn
1098-660Xpii
JCM.00877-16journal_volume
54pub_type
杂志文章abstract::Acinetobacter spp. are important nosocomial pathogens reported with increasing frequency in outbreaks of cross-infection during the past 2 decades. The majority of such outbreaks are caused by Acinetobacter baumannii. To investigate whether desiccation tolerance may be involved in the ability of certain strains of A. ...
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pub_type: 杂志文章
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pub_type: 杂志文章
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