Mutual effect of cerebral amyloid β and peripheral lymphocytes in cognitively normal older individuals.

abstract：OBJECTIVE:This study examines the short-term and long-term effects of a cognitive training (CT) program in enhancing cognitive function of older people with subjective memory complaints. METHODS:A single-blind randomized placebo-controlled trial was carried out in a sample of 223 older adults aged 65 years or above wi...

journal_title：International journal of geriatric psychiatry

authors： Kwok TC,Bai X,Li JC,Ho FK,Lee TM

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Apathy and depression are the most common neuropsychiatric features in Alzheimer's disease (AD). The clinical and functional specific correlates of these syndromes are not well known independently from cognitive deficits and other behavioral disturbances. MATERIAL AND METHODS:Six hundred and eighty-six pati...

journal_title：International journal of geriatric psychiatry

authors： Benoit M,Andrieu S,Lechowski L,Gillette-Guyonnet S,Robert PH,Vellas B,REAL-FR group.

更新日期：2008-04-01 00:00:00

abstract：:Less than one-tenth of all population-based research into dementia is directed towards the two-thirds or more of cases living in developing parts of the world. The 10/66 Dementia Research Group has been formed to redress this imbalance, encouraging active research collaboration between centres in different developing ...

journal_title：International journal of geriatric psychiatry

authors： Prince M

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:In the last decade, repetitive transcranial magnetic stimulation (rTMS) has been introduced as a non-invasive neuromodulation therapy for depression. Little is known, however, about (serious) adverse events (AE) of rTMS in older adults with a depression. In this article, we want to study what is known about (...

journal_title：International journal of geriatric psychiatry

authors： Overvliet GM,Jansen RAC,van Balkom AJLM,van Campen DC,Oudega ML,van der Werf YD,van Exel E,van den Heuvel OA,Dols A

更新日期：2020-10-09 00:00:00

abstract：OBJECTIVE:We evaluated the feasibility and acceptability of a tailored evidence-based intervention, consisting of a leaflet and a letter, to encourage timely help-seeking for dementia in Black elders. METHODS:Participating GP surgeries were randomised to send either the intervention or a control leaflet about ageing w...

journal_title：International journal of geriatric psychiatry

authors： Roche M,Mukadam N,Adelman S,Livingston G

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Proper screening of depression among older adults depends on accurate cut-off scores. Recent articles have recommended the Geriatric Depression Scale (GDS) and the Cornell Scale for Depression in Dementia (CSDD) for this screening. However, there has been no investigation of the sensitivity and specificity o...

journal_title：International journal of geriatric psychiatry

authors： Schreiner AS,Hayakawa H,Morimoto T,Kakuma T

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Most depression in older people is managed in primary care settings but can be difficult to diagnose and is often under-treated. This study examined the attitudes and practice of general practitioners in the treatment of late-life depression using antidepressant medication. METHOD:Three hundred and thirty g...

journal_title：International journal of geriatric psychiatry

authors： Rothera I,Jones R,Gordon C

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVES:To compare directly, in the same patient cohort, the ease of use and tolerability of donepezil and galantamine in the treatment of Alzheimer's disease (AD), and investigate the effects of both treatments on cognition and activities of daily living (ADL). METHODS:Patients with mild to moderate AD from 14 Eur...

journal_title：International journal of geriatric psychiatry

authors： Jones RW,Soininen H,Hager K,Aarsland D,Passmore P,Murthy A,Zhang R,Bahra R

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To systematically review and analyze the efficacy and tolerability of different antidepressant pharmacologic treatments for depressive symptoms in Parkinson's disease (PD) METHODS: We searched PubMed, EMBASE, Cochrane database (CENTRAL), clinicaltrials.gov, and bibliographies for randomized controlled trials ...

journal_title：International journal of geriatric psychiatry

authors： Mills KA,Greene MC,Dezube R,Goodson C,Karmarkar T,Pontone GM

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Posttraumatic stress disorder (PTSD) is a common and disabling condition following a traumatic event. Despite its high prevalence rates, relatively little is known about the manifestation and course of the disorder in older adults. Moreover, there has been little evaluation of the efficacy of psychotherapeuti...

journal_title：International journal of geriatric psychiatry

authors： Böttche M,Kuwert P,Knaevelsrud C

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVES:To investigate a presumed correlation between clock drawing ratings and linear measurements of computerized tomography (CT) studies in demented patients. DESIGN:Blinded evaluations of clock drawing tests and CT studies of elderly dementia patients were conducted by a geriatric psychiatrist and a neuroradiol...

journal_title：International journal of geriatric psychiatry

authors： Heinik J,Reider-Groswasser II,Solomesh I,Segev Y,Bleich A

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVES:Fear of falling (FoF) is common and associated with poorer functional outcomes after hip fracture. We sought to differentiate patterns of FoF at 4 and 12 weeks after surgical repair for hip fracture and examine predictors of FoF. METHODS/DESIGN:Secondary analysis of existing data from a 52-week prospective ...

journal_title：International journal of geriatric psychiatry

authors： Bower ES,Wetherell JL,Petkus AJ,Lenze EJ

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Alzheimer's disease (AD) is associated with both cognitive and behavioral symptoms. Agitation, hallucinations, delusions, aggression, irritability, and anxiety are observed in up to 90% of patients with dementia. Although new information has emerged in recent years on the treatment of psychosis and agitation...

journal_title：International journal of geriatric psychiatry

authors： Mintzer J,Faison W,Street JS,Sutton VK,Breier A

更新日期：2001-12-01 00:00:00

abstract：:As an elder's functional impairment increases, so in general does the tendency for the caregiver to intervene in the elder's daily activities and initiatives. To a certain extent, such intervention is necessary to compensate for the elder's loss of independent ability, and without such intervention, adverse outcomes f...

journal_title：International journal of geriatric psychiatry

authors： Fulmer T,Gurland B

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVE:To determine whether attentional impairments are reliable neuropsychological markers of delirium. METHOD:A prospective cohort of one hundred patients admitted for elective orthopaedic surgery, 70 years and over, and free of dementia were recruited from an Orthopaedic unit in a university teaching hospital. C...

journal_title：International journal of geriatric psychiatry

authors： Lowery DP,Wesnes K,Brewster N,Ballard C

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVES:This study investigated cognitive impairment in late-life depression in a follow-up design. The main objective was to assess the most important cognitive domains implicated in late-life depression, in patients who underwent pharmacological treatment, in the acute phase and twelve months after. METHODS:Neuro...

journal_title：International journal of geriatric psychiatry

authors： Portella MJ,Marcos T,Rami L,Navarro V,Gastó C,Salamero M

更新日期：2003-07-01 00:00:00

abstract：:Residents of nursing and residential homes are often prescribed medication for physical and mental ill-health with resultant polypharmacy and the possibility of iatrogenic disorders. Sometimes drugs are prescribed inappropriately and a number of studies have highlighted the overuse of psychotropic drugs. Legislation i...

journal_title：International journal of geriatric psychiatry

authors： Furniss L,Craig SK,Burns A

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:The aims of this study were to explore the knowledge, attitudes and beliefs that nursing home managers hold with regard to the assessment and management of pain in residents with dementia and to determine how these may be affected by the demographic characteristics of the respondents. METHODS:A questionnair...

journal_title：International journal of geriatric psychiatry

authors： Barry HE,Parsons C,Peter Passmore A,Hughes CM

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVES:The ventrolateral prefrontal cortex (vlPFC) has been speculated to play an important role in complex processes that allow emotional factors to influence human cognition. Accumulating evidence from human neuroimaging studies, in conjunction with studies of patients with lesions and animal models, shed light o...

journal_title：International journal of geriatric psychiatry

authors： Kim JU,Weisenbach SL,Zald DH

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Despite being simple and cheap, the EEG is not often used in clinical practice. METHODOLOGY:Literature search using PUBMED and Medline. RESULTS:Quantitative EEG can help to identify mild dementia and mild cognitive impairment and can increase diagnostic accuracy when used with other imaging techniques. EEG...

journal_title：International journal of geriatric psychiatry

authors： Adamis D,Sahu S,Treloar A

更新日期：2005-11-01 00:00:00

abstract：:The purpose of this article is to provide data for advanced interpretation of MMSE performance in community-dwelling elderly persons and in geriatric neuropsychiatry inpatients. Age- and education-corrected cutoff scores, standard errors of measurement and standard errors of difference were computed using previously p...

journal_title：International journal of geriatric psychiatry

authors： Iverson GL

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:The association between depression and an increased risk of death in elderly persons has been established in both clinical and community studies. Co-occurrence of depression and generalized anxiety has been shown to represent more severe and more chronic psychopathology. However, little is known about the re...

journal_title：International journal of geriatric psychiatry

authors： Holwerda TJ,Schoevers RA,Dekker J,Deeg DJ,Jonker C,Beekman AT

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the cost-consequences of an intervention for the management of neuropsychiatric symptoms in nursing home residents with young-onset dementia. METHODS:A stepped wedge design was used. The intervention consisted of an educational program and a multidisciplinary care program and was implemented in 1...

journal_title：International journal of geriatric psychiatry

authors： van Duinen-van den IJssel JCL,Bakker C,Smalbrugge M,Zwijsen SA,Adang E,Appelhof B,Zuidema SU,de Vugt ME,Verhey FRJ,Koopmans RTCM

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:To assess the effect of an interdisciplinary educational program in reducing the use of antipsychotics in nursing home residents with dementia. METHODS:We conducted a longitudinal pilot study to test the implementation of a 7-month interdisciplinary educational program in a fixed cohort of residents with dem...

journal_title：International journal of geriatric psychiatry

authors： Monette J,Champoux N,Monette M,Fournier L,Wolfson C,du Fort GG,Sourial N,Le Cruguel JP,Gore B

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:The aim of the study is to investigate the performance of the clock drawing test as a screening tool for cognitive impairment in Huntington's disease (HD) mutation carriers. METHODS:The performance of the clock drawing test was assessed in 65 mutation carriers using the Shulman and the Freund scoring system...

journal_title：International journal of geriatric psychiatry

authors： Terwindt PW,Hubers AA,Giltay EJ,van der Mast RC,van Duijn E

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVES/METHODS:Ten patients with neuropathologically verified frontotemporal dementia (FTD) were analysed for neuropathological features in relation to first presenting and dominating symptoms, age at onset and duration of dementia, as well as to EEG/quantitative EEG. RESULTS:Cases with a late onset (> 65 years) i...

journal_title：International journal of geriatric psychiatry

authors： Passant U,Rosén I,Gustafson L,Englund E

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:To investigate associations between vision impairment (VI), vision correction (VC) and depressive symptoms among middle-aged and older Chinese. METHODS:22 203 participants aged ≥45 years from China Health and Retirement Longitudinal Study 2011 to 2015 were divided into four self-reported VI categories: no VI...

journal_title：International journal of geriatric psychiatry

authors： Zhang Q,Cao GY,Yao SS,Wang C,Chen ZS,Hu YH,Xu B

更新日期：2021-01-01 00:00:00

abstract：AIM:To evaluate the influence of premorbid personality on adaptation to placement in a long-term care facility. SUBJECTS:Twenty-eight persons with probable Alzheimer disease (AD) residing in an academically affiliated nursing home for 6-9 months. METHODS:Premorbid personality was described retrospectively by two info...

journal_title：International journal of geriatric psychiatry

authors： Brandt J,Campodonico JR,Rich JB,Baker L,Steele C,Ruff T,Baker A,Lyketsos C

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVES:Patient expectations of treatment effects could influence neuropsychological and clinical outcomes in clinical trials of behavioral and lifestyle interventions, which could potentially confound the interpretation of findings. Our aim was to examine whether patient expectancy mediated effectiveness of Mindful...

journal_title：International journal of geriatric psychiatry

authors： Haddad R,Lenze EJ,Nicol G,Miller JP,Yingling M,Wetherell JL

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Deliberate self harm (DSH) in later life is under researched and is believed to be related to both mental illness and suicide. AIMS:The aim of the study was to examine deliberate self-harm (DSH) in older people presenting to acute hospital services over three years. METHOD:This was a retrospective observat...

journal_title：International journal of geriatric psychiatry

authors： Lamprecht HC,Pakrasi S,Gash A,Swann AG

更新日期：2005-11-01 00:00:00