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Inferior J waves in patients with vasospastic angina might be a risk factor for ventricular fibrillation.

Abstract：

BACKGROUND:There is little information about the relationship between J waves and the occurrence of ventricular fibrillation (VF) in patients with vasospastic angina (VSA). The present study aimed to assess the incidence of J waves and the occurrence of VF in patients with VSA. METHODS:The subjects consisted of 62 patients with VSA diagnosed by acetylcholine provocation tests in our institution from 2002 to 2014. We investigated the VF events, prevalence of J waves, and relationship between the VF events and J waves. RESULTS:J waves were observed in 16 patients (26%) and VF events were documented in 11 (18%). The incidence of VF in the patients with J waves was significantly higher than that in those without J waves (38% vs 11%, p=0.026). J waves were observed in the inferior leads in 14 patients, lateral leads in 5, and anterior leads in 3. A univariate analysis indicated that the incidence of VF in the inferior leads of J wave positive patients (46%=6/14) was significantly (p=0.01) higher than that in the inferior leads of J wave negative patients (10%=5/48). The J waves in the anterior and/or lateral leads were not related to the incidence of VF. Notched type and slurred type J waves were not associated with VF. A multivariate analysis revealed that J waves in VSA patients were associated with VF [odds ratio (OR) 6.41, 95% confidence interval (CI) 1.37-29.93, p=0.02] and organic stenosis (OR 6.98, 95% CI 1.39-35.08, p=0.02). Further, J waves in the inferior leads were strongly correlated with VF (OR 11.85, 95% CI 2.05-68.42, p=0.006). CONCLUSIONS:The results suggest that the existence of J waves, especially in the inferior leads, might be a risk factor for VF in VSA patients.

journal_name

J Cardiol

journal_title

Journal of cardiology

authors

Fumimoto T,Ueyama T,Shimizu A,Yoshiga Y,Ono M,Kato T,Ishiguchi H,Okamura T,Yamada J,Yano M

doi

10.1016/j.jjcc.2016.12.003

subject

Has Abstract

pub_date

2017-09-01 00:00:00

pages

271-277

issue

3

eissn

0914-5087

issn

1876-4738

pii

S0914-5087(16)30344-6

journal_volume

70

pub_type

杂志文章

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