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[Highly concentrated vascular endothelial growth factor in Crow-Fukase syndrome with high output heart failure: a case report].

Abstract：

:Crow-Fukase syndrome is a disease of plasma cell dyscrasia. Congestive heart failure is the biggest complication affecting the prognosis. A 57-year-old male was admitted with edema and low grade fever. Globe and stocking type polyneuropathy, increased levels of adrenocorticotropic hormone and thyroid-stimulating hormone, serum M-protein component of the immunoglobulin A-lambda type, skin polypoid lesion, and organomegaly including cardiomegaly were observed. The diagnosis was Crow-Fukase syndrome based on these clinical features. High output heart failure and pulmonary hypertension were determined with a cardiac catheter. Diuretics and angiotensin converting enzyme inhibitor were effective to control his overhydration. The level of serum vascular endothelial growth factor was markedly increased and might be responsible for the manifestation of this syndrome with cardiac involvement.

journal_name

J Cardiol

journal_title

Journal of cardiology

authors

Shiraki T,Satoh S,Sugiyama H,Kobayashi M,Takamura T,Kajiyama A,Saito D

subject

Has Abstract

pub_date

2005-02-01 00:00:00

pages

75-80

issue

2

eissn

0914-5087

issn

1876-4738

journal_volume

45

pub_type

杂志文章

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