Abstract:
BACKGROUND:The most prevalent and serious infection related to left ventricular assist devices (LVADs) is driveline infection (DLI). From 2014, we employed a revised surgical technique (triple tunnel method), which deployed a longer subfascial driveline (DL) route. METHODS AND PATIENTS:We retrospectively analyzed 34 patients fitted with either of the two types of axial pumps: HeartMate II (n=23) and Jarvik 2000 (n=11). Prior to 2014, the DL proceeded from the pump pocket just above the posterior sheath of the rectus muscle toward a vertical skin incision at the right lateral border of the rectus muscle. Then, DL was turned leftward into the subcutaneous tissue to redirect its exit to the left side [subcutaneous tissue group (Group S): n=14]. From 2014, we made an additional skin incision below the umbilicus with the aim of lengthening the subfascial DL route [muscle group (Group M): n=20]. RESULTS:DLI occurred in 10 patients (71.4%) in Group S and in 1 patient (5%) in Group M (p<0.05, Chi-square test). The freedom rate from re-admission at 1 year due to DLI was 64% in Group S and 95% in Group M, respectively (p=0.021, log-rank test). Furthermore, logistic regression analysis revealed that DL route was significantly associated with DLI (odds ratio, 10.1; 95% confidence interval, 1.15-275.3). CONCLUSION:Although a longer follow-up period will be needed, the triple tunnel method may be beneficial in the prevention of DLI.
journal_name
J Cardioljournal_title
Journal of cardiologyauthors
Yoshitake S,Kinoshita O,Nawata K,Hoshino Y,Itoda Y,Kimura M,Yamauchi H,Ono Mdoi
10.1016/j.jjcc.2018.04.003subject
Has Abstractpub_date
2018-10-01 00:00:00pages
363-366issue
4eissn
0914-5087issn
1876-4738pii
S0914-5087(18)30109-6journal_volume
72pub_type
杂志文章abstract::Diabetes mellitus may be an independent risk factor for disturbance of cardiac function, but the detailed mechanism remains unclear. In the present study, histological examinations were carried out on 25 hearts from diabetes model rats as well as myocardial biopsy materials from patients with diabetes (n = 25). The me...
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journal_title:Journal of cardiology
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doi:
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