Inflammation of left atrial epicardial adipose tissue is associated with paroxysmal atrial fibrillation.

Abstract:

BACKGROUND:Although an increased epicardial adipose tissue (EAT) volume around the left atrium (LA) is related to the atrial fibrillation (AF) burden, the role of EAT inflammation in AF is unclear. We investigated the association between AF and inflammation of the EAT around the LA. METHODS:We retrospectively identified regions of EAT around the LA and measured the density of these areas using computed tomography (CT). RESULTS:A total of 32 patients who underwent their first catheter ablation for paroxysmal AF (PAF) were enrolled (mean age 62.5±11.1 years). Patients without a history of AF (n=32), but who underwent cardiac CT and were matched by age, sex, and metabolic risk factors, were enrolled in the control group (62.2±12.1 years). The mean EAT density around the LA was significantly higher in the PAF group than in the control group (-108.1±6.7 vs. -111.6±5.5 Hounsfield units; p=0.02), while the densities of subcutaneous adipose tissue (SAT) in the abdomen and thorax did not differ between the two groups. In a multiple logistic regression analysis, a higher EAT density was significantly associated with the presence of PAF after adjusting for other risk factors (odds ratio: 1.25; 95% confidence interval: 1.08-1.45, p=0.003). CONCLUSIONS:This study supports the hypothesis that inflammation of EAT around the LA, but not SAT, is related to the presence of PAF.

journal_name

J Cardiol

journal_title

Journal of cardiology

authors

Kusayama T,Furusho H,Kashiwagi H,Kato T,Murai H,Usui S,Kaneko S,Takamura M

doi

10.1016/j.jjcc.2015.11.005

subject

Has Abstract

pub_date

2016-11-01 00:00:00

pages

406-411

issue

5

eissn

0914-5087

issn

1876-4738

pii

S0914-5087(15)00371-8

journal_volume

68

pub_type

杂志文章
  • Physical activity and progression of carotid intima-media thickness in patients with coronary heart disease.

    abstract:OBJECTIVE:We conducted the present study to determine the level of physical activity required to retard the progression of carotid intima-media thickness (IMT) in patients with coronary heart disease (CHD). PATIENTS AND MAIN OUTCOME MEASUREMENTS:The daily walking distance (km/day) of 40 patients with CHD (male/female ...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2008.02.005

    authors: Sato S,Makita S,Uchida R,Ishihara S,Majima M

    更新日期:2008-06-01 00:00:00

  • [Intravascular ultrasound guided polytetrafluoroethylene coronary stent graft implantation in a patient with a large coronary pseudoaneurysm at eight months after coronary intervention: a case report].

    abstract::A 67-year-old man with exertional angina presented with a large pseudoaneurysm of the right coronary artery at eight months after balloon angioplasty. Intravascular ultrasound revealed a large saccular pseudoaneurysm of 10.9 x 5.7 mm diameter at the proximal segment of the right coronary artery. Complete closure of th...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Yasukawa T,Ozaki Y,Kakihana M,Shinjo H,Waseda K,Kuroda Y,Asai K,Wakita Y,Kono T,Takashima H,Ito T

    更新日期:2003-12-01 00:00:00

  • [Hypertrophic obstructive cardiomyopathy with ruptured mitral chordae tendineae: a case report].

    abstract::A 61-year-old man was treated medically under a diagnosis of hypertrophic obstructive cardiomyopathy 7 years previously. He was transferred to our hospital because of sudden onset of dyspnea. Chest radiography showed marked pulmonary congestion. Echocardiography revealed hypertrophic obstructive cardiomyopathy, with a...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Wakeyama T,Ogawa H,Takaki A,Iwami T,Kimura M,Tanaka T,Uchinoumi H

    更新日期:2004-08-01 00:00:00

  • [Clinical and echocardiographic evaluation of the effects of atrial defibrillation in patients with idiopathic cardiomyopathy].

    abstract::To elucidate the effects of atrial defibrillation in patients with idiopathic cardiomyopathy, we clinically and echocardiographically assessed 6 patients with hypertrophic cardiomyopathy (HCM) and 7 patients with dilated cardiomyopathy (DCM). Their mean age was 57 +/- 14 years and the mean duration of their atrial fib...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Shite J,Yokota Y,Nakatani M,Takeuchi Y,Tsumura Y,Kawai H,Ueno H,Kawashima T,Honda Y

    更新日期:1992-01-01 00:00:00

  • Risk factors of non-sustained ventricular tachycardia by technetium-perfusion imaging in patients with coronary artery lesions caused by Kawasaki disease.

    abstract:BACKGROUND:Sudden death can occur in some patients with non-sustained ventricular tachycardia (NSVT) after myocardial infarction (MI) in those with coronary artery lesions (CAL) caused by Kawasaki disease (KD). The aim of this study was to determine the risk factors for NSVT in the late period after KD by technetium-99...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2018.12.007

    authors: Abe T,Tsuda E,Sugiyama H,Kiso K,Yamada O

    更新日期:2019-05-01 00:00:00

  • Heart rate control with single administration of a long-acting β-blocker at bedtime before coronary computed tomography angiography.

    abstract:BACKGROUND:Beta-blockers are used to control the heart rate prior to coronary computed tomography (CT) angiography. However, in-hospital administration is time-consuming, and it is hard to decrease the heart rate to <60 beats per minute (bpm) when the initial heart rate is increased. In this study, we examined whether ...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2014.07.007

    authors: Sadamatsu K,Koide S,Nakano K,Yoshida K

    更新日期:2015-04-01 00:00:00

  • Independent and cumulative association of clinical and morphological heart failure with long-term outcome after percutaneous coronary intervention.

    abstract:BACKGROUND:Heart failure (HF) is a risk factor for adverse post-procedural outcome after revascularization; however, it is unclear how left ventricular systolic dysfunction (LVSD) and clinical HF symptoms affect percutaneous coronary intervention (PCI) outcomes. We investigated the characteristics and long-term outcome...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2020.06.014

    authors: Kimura M,Kohno T,Sawano M,Heidenreich PA,Ueda I,Takahashi T,Matsubara T,Ueno K,Hayashida K,Yuasa S,Ohki T,Fukuda K,Kohsaka S

    更新日期:2021-01-01 00:00:00

  • Meta-analysis of transcatheter aortic valve implantation for bicuspid versus tricuspid aortic valves.

    abstract:BACKGROUND:We performed meta-analysis and meta-regression of transcatheter aortic valve implantation (TAVI) for the bicuspid aortic valve (B-AV) versus the tricuspid aortic valve (T-AV). METHODS:MEDLINE and EMBASE were searched through June 2018 using PubMed and OVID. We included comparative studies of TAVI patients w...

    journal_title:Journal of cardiology

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.jjcc.2019.03.018

    authors: Takagi H,Hari Y,Kawai N,Kuno T,Ando T,ALICE (All-Literature Investigation of Cardiovascular Evidence) Group.

    更新日期:2019-07-01 00:00:00

  • The importance of serial cardiac troponin measurement for evaluating the response to immunosuppressive therapy for myocarditis.

    abstract::A 71-year-old woman was admitted to our department because of acute myocarditis. She was ameliorated with conventional heart failure treatment, however she developed left ventricular dilatation and cardiac troponin T (cTnT) was elevated again to >1.0 ng/ml 6 month after the first admission. She was re-admitted because...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2008.05.002

    authors: Kadota S,Takeuchi Y,Izuhara M,Baba O,Shioji K,Uegaito T,Kadota E,Matsuda M

    更新日期:2008-10-01 00:00:00

  • [Visualization of internal mammary artery bypass graft flow using a linear color flow mapping system with a convex type transducer].

    abstract::To evaluate noninvasively the patency of aortocoronary bypass grafts using the left internal mammary artery (LIMAG), color flow mapping Doppler echocardiography was performed in 23 consecutive patients. There were 22 males and one female. The average number of involved coronary arteries per patient was 2.5 +/- 0.6. Th...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Kyo S,Matsumura M,Takamoto S,Yokote Y,Omoto R

    更新日期:1989-03-01 00:00:00

  • Elevated concentrations of pentraxin 3 are associated with coronary plaque vulnerability.

    abstract:BACKGROUND:Inflammation is a critical contributing factor to the development and progression of atherosclerosis. Pentraxin 3 (PTX3) is produced abundantly in atherosclerotic lesions while C-reactive protein (CRP) is mainly produced in the liver. In this study, we investigated whether plasma levels of PTX3 might be a se...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2011.04.005

    authors: Soeki T,Niki T,Kusunose K,Bando S,Hirata Y,Tomita N,Yamaguchi K,Koshiba K,Yagi S,Taketani Y,Iwase T,Yamada H,Wakatsuki T,Akaike M,Sata M

    更新日期:2011-09-01 00:00:00

  • Ablation perioperative dabigatran in use envisioning in Japan: The ABRIDGE-J Study Design.

    abstract:BACKGROUND:Catheter ablation has become a standard treatment strategy for drug-resistant symptomatic non-valvular atrial fibrillation (NVAF). Periprocedural administration of uninterrupted warfarin could reduce the risk of thromboembolic complications. However, only a few retrospective studies have reported on the effi...

    journal_title:Journal of cardiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jjcc.2015.10.003

    authors: Goya M,Nogami A,Hirao K,Aonuma K

    更新日期:2016-09-01 00:00:00

  • Prognostic value of global left ventricular strain for conservatively treated patients with symptomatic aortic stenosis.

    abstract:AIMS:Impaired left ventricular (LV) strain is associated with an increased risk of cardiac events in asymptomatic severe aortic stenosis (AS). We aimed to evaluate the prognostic value of global LV strain in conservatively treated patients with symptomatic AS. METHODS AND RESULTS:This cohort study retrospectively revi...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2013.05.001

    authors: Lee HF,Hsu LA,Chan YH,Wang CL,Chang CJ,Kuo CT

    更新日期:2013-11-01 00:00:00

  • Multifocal fibrosclerosis and IgG4-related disease involving the cardiovascular system.

    abstract::The cardiovascular system may be involved as a target organ of multifocal fibrosclerosis, which may manifest as idiopathic retroperitoneal fibrosis, inflammatory aortic aneurysm, inflammatory periarteritis, and inflammatory pericarditis. These pathological conditions can sometimes occur concomitantly. Idiopathic retro...

    journal_title:Journal of cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jjcc.2011.10.005

    authors: Ishizaka N,Sakamoto A,Imai Y,Terasaki F,Nagai R

    更新日期:2012-03-01 00:00:00

  • Low left atrial appendage flow velocity predicts recurrence of atrial fibrillation after catheter ablation of persistent atrial fibrillation.

    abstract:BACKGROUND:Recurrence after catheter ablation of persistent atrial fibrillation (AF) remains an unsolved issue. This study aimed to explore the association between the left atrial appendage peak flow velocity (LAAV) and AF recurrence after ablation in persistent AF patients. METHODS:Fifty-three consecutive patients wh...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2015.04.009

    authors: Kanda T,Masuda M,Sunaga A,Fujita M,Iida O,Okamoto S,Ishihara T,Watanabe T,Takahara M,Sakata Y,Uematsu M

    更新日期:2015-11-01 00:00:00

  • The Sequential Organ Failure Assessment (SOFA) score predicts mortality and neurological outcome in patients with post-cardiac arrest syndrome.

    abstract:BACKGROUND:Patients experiencing out-of-hospital cardiac arrest (OHCA) and subsequent post-cardiac arrest syndrome are often compromised by multi-organ failure. The Sequential Organ Failure Assessment (SOFA) score has been used to predict clinical outcome of patients requiring intensive care for multi-organ failure. Th...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2020.03.007

    authors: Matsuda J,Kato S,Yano H,Nitta G,Kono T,Ikenouchi T,Murata K,Kanoh M,Inamura Y,Takamiya T,Negi K,Sato A,Yamato T,Inaba O,Morita H,Matsumura Y,Nitta J,Yonetsu T

    更新日期:2020-09-01 00:00:00

  • [Anaerobic threshold and oxygen uptake in patients with mitral stenosis].

    abstract::The exercise stress test with a bicycle ergometer was performed for 31 patients with mitral stenosis and for 10 normal subjects. The patients were categorized in two groups. Group 1 consisted of 16 patients having indication for surgical intervention and Group 2 consisted of 15 patients without such surgical indicatio...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Kawauchi M,Matsunaga H,Makuuchi H,Okabe H,Miyairi T,Morizuki O,Furuse A

    更新日期:1989-09-01 00:00:00

  • [Relationship between long-term preventive efficacy of cibenzoline and atrial natriuretic peptide in patients with paroxysmal atrial fibrillation].

    abstract:OBJECTIVES:The relationship between the long-term efficacy of the antiarrhythmic agent cibenzoline in preventing lone paroxysmal atrial fibrillation (PAf) and plasma concentrations of atrial natriuretic peptide (ANP) and catecholamine was investigated during sinus rhythm and PAf. METHODS:Plasma concentrations of ANP, ...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Komatsu T,Nakamura S,Kimura M,Owada S,Yomogida K,Kameda K,Oikawa K,Tomita H,Okumura K

    更新日期:2002-02-01 00:00:00

  • Real clinical management of patients with isolated superior mesenteric artery dissection in Japan.

    abstract:BACKGROUND:Due to the rarity of this condition, clinical treatment and outcomes in isolated superior mesenteric artery dissection (ISMAD) patients remain unknown. The primary aim of this retrospective multicenter study was to elucidate the treatment strategies and in-hospital outcomes for ISMAD patients by using admini...

    journal_title:Journal of cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jjcc.2017.08.006

    authors: Mizuno A,Iguchi H,Sawada Y,Nomura H,Komiyama N,Watanabe S,Yoshikawa A

    更新日期:2018-02-01 00:00:00

  • Colestimide, an anion exchange resin agent, can decrease the number of LDL particles without affecting their size in patients with hyperlipidemia.

    abstract:OBJECTIVES:Recent studies have demonstrated that not only plasma low-density lipoprotein (LDL) levels, but also the number of small dense LDL particles are involved in the development of arteriosclerosis. Anion exchange resins can reduce plasma LDL levels and affect LDL particle size via increasing triglycerides. In th...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2009.08.006

    authors: Kishimoto N,Fujii S,Chiba H,Sakuma I,Tsutsui H

    更新日期:2010-01-01 00:00:00

  • Mobilization of sca1/flk-1 positive endothelial progenitor cells declines in apolipoprotein E-deficient mice with a high-fat diet.

    abstract:BACKGROUND:Atherosclerosis features a deterioration of the endothelial layer in all stages. Restoration of the endothelium is associated with circulating stem cell antigen 1 (sca1) and vascular endothelial growth factor receptor type 2 (flk-1) positive endothelial progenitor cells (EPCs). We investigated whether EPC pr...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2015.02.008

    authors: Steinmetz M,Lucanus E,Zimmer S,Nickenig G,Werner N

    更新日期:2015-12-01 00:00:00

  • Transient left ventricular apical ballooning developing after the Central Niigata Prefecture Earthquake: two case reports.

    abstract::Two patients presented with transient left ventricular apical ballooning (takotsubo cardiomyopathy) induced by emotional stress caused by the Central Niigata Prefecture Earthquake in 2004. These patients complained of chest pain immediately after the earthquake. In patient 1, electrocardiography (ECG) showed slight ST...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Tagawa M,Nakamura Y,Ishiguro M,Satoh K,Chinushi M,Kodama M,Aizawa Y

    更新日期:2006-09-01 00:00:00

  • [Significance of percutaneous transluminal coronary intervention for chronic total occlusions assessed as non-viable by myocardial scintigraphy].

    abstract:OBJECTIVES:The effectiveness of percutaneous transluminal coronary intervention (PCI) was evaluated for chronic total occlusion (CTO) assessed as non-viable by myocardial scintigraphy. METHODS:In the period from January 2003 to October 2006, 17 patients who had successful reopening of the artery through revascularizat...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Nii H,Wagatsuma K,Kabuki T,Uchida Y,Amano H,Toda M,Yamashina S,Yamazaki J

    更新日期:2007-12-01 00:00:00

  • [Angina with long-standing coronary T waves].

    abstract::The clinical significance of long-standing (greater than or equal to 24 hours) coronary T waves without abnormal Q waves was evaluated in 24 patients with angina. They were categorized in two groups; 11 with ST elevation followed by coronary T waves (Group A), and 13 with coronary T waves alone (Group B). 1. The patie...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Hamashige N,Doi Y,Odawara H,Yonezawa Y,Kuzume O,Chikamori T,Ozawa T

    更新日期:1988-09-01 00:00:00

  • [Percutaneous transluminal coronary angioplasty in patients with multivessel coronary disease: does complete revascularization improve the long-term survival?].

    abstract::The influence of complete revascularization on long-term outcome of patients with multivessel coronary artery disease undergoing percutaneous transluminal coronary angioplasty (PTCA) was determined by analysis of 10-year survival in 167 consecutive patients treated at Juntendo University Hospital during 1984-1993. For...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Ohta H,Daida H,Ohashi S,Sunayama S,Fujiwara Y,Miyauchi K,Yokoi H,Yamaguchi H

    更新日期:1997-05-01 00:00:00

  • [Deep vein thrombosis caused by pelvic lymphocyst following radical prostatectomy: a case report].

    abstract::A 66-year-old man was admitted with distal edema of his right leg. He had undergone radical prostatectomy and pelvic lymphadenectomy for prostatic cancer 23 days previously. Abdominal computed tomography (CT) showed a lymphocyst (4.5 x 3.0 cm) along the right pelvic wall compressing the right external iliac vein. CT w...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Hirabayashi N,Sakurai S,Komiyama I,Yokoyama J,Kontani K,Yoneyama T,Hirase Y,Koshihara H,Itoh A,Ikeda U

    更新日期:2005-06-01 00:00:00

  • [Greenfield filter placement following successful cardiopulmonary resuscitation in a patient with sudden death due to pulmonary embolization].

    abstract::A 54-year-old man was admitted as an emergency following an episode of syncope and severe dyspnea. The clinical presentation and laboratory data strongly suggested pulmonary embolism, so intravenous thrombolytic therapy was performed. Immediately following the initiation of thrombolytic therapy, the patient experience...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Ishizaka N,Ohno E,Kawauchi N,Shimizu T,Kojima T,Ohno M,Kurokawa K

    更新日期:1995-09-01 00:00:00

  • [Relationship between early peaking of serum myosin light chain 1 level and washout phenomenon of creatine kinase in acute myocardial infarction].

    abstract::To investigate the serum levels of myosin light chain 1 (MLC1) during the acute phase of myocardial infarction, the MLC1 and creatine kinase (CK) levels were measured in samples from 59 consecutive patients with acute myocardial infarction. The serum concentration of MLC1 increased rapidly, reaching an early peak in 2...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Okumachi F,Yoshikawa J,Koizumi K,Shiratori K,Yoshida K,Akasaka T,Maeda K,Takagi T,Minagoe S,Kato H

    更新日期:1994-03-01 00:00:00

  • Low-dose dobutamine induces left ventricular mechanical dyssynchrony in patients with dilated cardiomyopathy and a narrow QRS: a study using real-time three-dimensional echocardiography.

    abstract:AIMS:The effects of inotropic agents on left ventricular (LV) synchrony in heart failure patients are still unknown. The purpose of this study was to investigate the effects of dobutamine on LV mechanical dyssynchrony and LV systolic performance in patients with dilated cardiomyopathy (DCM) and a narrow QRS using real-...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2012.12.012

    authors: Yagishita-Tagawa Y,Abe Y,Arai K,Yagishita D,Takagi A,Ashihara K,Shoda M,Naruko T,Itoh A,Haze K,Yoshikawa J,Hagiwara N

    更新日期:2013-04-01 00:00:00

  • Secondary sarcopenia assessed by computed tomography can predict hospitalization for heart failure in adults with Fontan circulation.

    abstract:BACKGROUND:Sarcopenia is one of the important predictors of heart failure (HF) in patients with cardiac problems. Skeletal muscle pump is important to maintain Fontan circulation. We aimed to quantify the volume of the psoas major muscle (PMM) and investigate whether it is relevant to HF hospitalization in adults with ...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2020.06.009

    authors: Shiina Y,Nagao M,Shimomiya Y,Inai K

    更新日期:2021-01-01 00:00:00