Abstract:
OBJECTIVE:We conducted the present study to determine the level of physical activity required to retard the progression of carotid intima-media thickness (IMT) in patients with coronary heart disease (CHD). PATIENTS AND MAIN OUTCOME MEASUREMENTS:The daily walking distance (km/day) of 40 patients with CHD (male/female ratio: 37/3, mean age: 61.2 years, mean interval time after a coronary event 16.2 months) was examined. Carotid IMT examinations (B-mode ultrasonography) were performed at the baseline and after 6 months. RESULTS:Among the patients, the average walking distance was 4.00km/day. Walking distance was inversely associated with IMT progression (r=-0.51, p<0.01). Multivariate logistic regression analysis revealed that walking distance (p=0.024) is a predictor for IMT progression independent of classical cardiovascular risk factors. Receiver operating characteristic analysis showed that the walking distance of 4.25km was strongly predictive of IMT preservation (sensitivity 64.0%, specificity 73.3%) in CHD patients. CONCLUSIONS:Our data suggested that an increase in the daily walking distance could retard the progression of carotid IMT in patients with CHD. Cardiology medical staff should encourage their patients to expend an average of 4-5km in daily walking distance for the secondary prevention of cardiovascular disease.
journal_name
J Cardioljournal_title
Journal of cardiologyauthors
Sato S,Makita S,Uchida R,Ishihara S,Majima Mdoi
10.1016/j.jjcc.2008.02.005subject
Has Abstractpub_date
2008-06-01 00:00:00pages
157-62issue
3eissn
0914-5087issn
1876-4738pii
S0914-5087(08)00090-7journal_volume
51pub_type
杂志文章abstract::The spasm provocation tests of ergonovine and acetylcholine have been employed in the cardiac catheterization laboratory. Ergonovine acts through the serotogenic receptors, while acetylcholine acts through the muscarinic cholinergic receptors. Different mediators may have the potential to cause different coronary resp...
journal_title:Journal of cardiology
pub_type: 杂志文章,评审
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journal_title:Journal of cardiology
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更新日期:1996-01-01 00:00:00
abstract::A 54-year-old man was admitted as an emergency following an episode of syncope and severe dyspnea. The clinical presentation and laboratory data strongly suggested pulmonary embolism, so intravenous thrombolytic therapy was performed. Immediately following the initiation of thrombolytic therapy, the patient experience...
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pub_type: 杂志文章,评审
doi:
更新日期:1998-01-01 00:00:00
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journal_title:Journal of cardiology
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更新日期:1991-01-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 杂志文章,评审
doi:
更新日期:1999-03-01 00:00:00
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pub_type: 临床试验,杂志文章
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journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2003-07-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2014.02.012
更新日期:2014-11-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1988-12-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2011.07.009
更新日期:2011-11-01 00:00:00
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pub_type: 杂志文章
doi:
更新日期:2006-11-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-05-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 临床试验,杂志文章
doi:
更新日期:2000-02-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1988-06-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2011.12.003
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pub_type: 杂志文章
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journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
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更新日期:2018-05-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2017-04-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1987-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:2014-08-01 00:00:00
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pub_type: 杂志文章,meta分析
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更新日期:2019-07-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 临床试验,杂志文章
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更新日期:1995-12-01 00:00:00
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