A novel risk prediction score in atrial fibrillation for a net clinical outcome from the ENGAGE AF-TIMI 48 randomized clinical trial.

abstract：:Recent studies have illustrated that in addition to the well known risk factors, such as lipoproteins, smoking, hypertension, there are others that cause atherosclerosis and myocardial infarction. Our knowledge of atherosclerotic lesions has increased. We now know that atherosclerotic changes are due to inflammatory c...

journal_title：European heart journal

authors： Nieminen MS,Mattila K,Valtonen V

更新日期：1993-12-01 00:00:00

abstract：Aims:Optimal blood pressure for prevention of cardiovascular (CV) events in patients with Type 2 diabetes mellitus (T2DM) remains uncertain and there is concern for increased risk with low diastolic blood pressure (DBP). This study analysed the association between blood pressure and CV outcomes in high-risk patients wi...

journal_title：European heart journal

authors： Bergmark BA,Scirica BM,Steg PG,Fanola CL,Gurmu Y,Mosenzon O,Cahn A,Raz I,Bhatt DL,SAVOR-TIMI 53 Investigators.

更新日期：2018-06-21 00:00:00

abstract：AIMS:Metalloproteinases are proteolytic enzymes, which decompose the extracellular matrix, influence cardiac remodelling, and are inhibited by tissue inhibitor of metalloproteinases (TIMPs). Little is known about the prognostic impact of the TIMP-1/matrix metalloproteinase complex in patients with future cardiovascular...

journal_title：European heart journal

authors： Lubos E,Schnabel R,Rupprecht HJ,Bickel C,Messow CM,Prigge S,Cambien F,Tiret L,Münzel T,Blankenberg S

更新日期：2006-01-01 00:00:00

abstract：:Forty patients with prosthetic valve endocarditis (PVE) presenting during a 12-year period at a single hospital were studied. Twenty-six were male and 14 female and ages ranged from 19 to 67 years. During the first six post-operative months, most episodes were caused by staphylococci (38%) and Gram negative bacilli (2...

journal_title：European heart journal

authors： Gayet JL,Etienne J,Malquarti V,Gruer LD,Didier B,Chuzel M,Champsaur G,Chassignolle J,Fleurette J,Delaye J

更新日期：1984-10-01 00:00:00

abstract：AIMS:The anti-anginal efficacy and safety of ranolazine in diabetic and non-diabetic patients included in the Combination Assessment of Ranolazine In Stable Angina (CARISA) trial (JAMA 2004;291:309) were studied. Glycaemic control was also assessed in CARISA and its long-term open-label extension study. METHODS AND RE...

journal_title：European heart journal

authors： Timmis AD,Chaitman BR,Crager M

更新日期：2006-01-01 00:00:00

abstract：AIMS:Hyponatraemia has been shown to be an independent predictor of mortality in selected patients with heart failure enrolled in clinical trials. The predictive value of hyponatraemia has not been evaluated in unselected patients hospitalized with heart failure. METHODS AND RESULTS:OPTIMIZE-HF is a registry and perfo...

journal_title：European heart journal

authors： Gheorghiade M,Abraham WT,Albert NM,Gattis Stough W,Greenberg BH,O'Connor CM,She L,Yancy CW,Young J,Fonarow GC,OPTIMIZE-HF Investigators and Coordinators.

更新日期：2007-04-01 00:00:00

abstract：:The steady state plasma concentrations of the two platelet-specific proteins beta-thromboglobulin (BTG) and platelet factor 4 (PF4) were determined in two groups of females: 36 acute myocardial infarction (AMI) survivors, and 38 age-matched control subjects. For the AMI patients the mean BTG and PF4 values were 57 +/-...

journal_title：European heart journal

authors： Kutti J,Johansson S,Eriksson KA,Sigvaldason A,Vedin A,Wadenvik H,Wilhelmsson C

更新日期：1983-05-01 00:00:00

abstract：:In order to assess the value of pulsed Doppler echocardiography in detection of valvular regurgitation, 63 patients were evaluated for aortic and/or mitral regurgitation using pulsed Doppler echocardiography and selective cineangiography. The Doppler study was considered as positive when a turbulent flow was detected ...

journal_title：European heart journal

authors： Wautrecht JC,Vandenbossche JL,Englert M

更新日期：1984-05-01 00:00:00

abstract：AIMS:To investigate whether Atorvastatin (Ator) treatment improves the cardiac micro-environment that facilitates survival and differentiation of bone-marrow-derived mesenchymal stem cells (MSCs) implanted in the post-infarct myocardium. METHODS AND RESULTS:Myocardial infarction was created by coronary ligation and im...

journal_title：European heart journal

authors： Yang YJ,Qian HY,Huang J,Geng YJ,Gao RL,Dou KF,Yang GS,Li JJ,Shen R,He ZX,Lu MJ,Zhao SH

更新日期：2008-06-01 00:00:00

abstract：:From a clinicopharmacological standpoint, the urinary excretory potency of diuretics should be assessed comparatively, on the basis of placebo-controlled changes in 24 h natriuresis, following single oral doses administered to healthy adult subjects who are in steady-state habitual external sodium balance. The potency...

journal_title：European heart journal

authors： Reyes AJ

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:Recent experimental and clinical data indicate that abnormal central and peripheral immune reactions contribute to the progression of chronic heart failure, and that immunomodulation may be an important therapeutic approach in this syndrome. Aims We sought to study the effects of growth hormone (GH) administ...

journal_title：European heart journal

authors： Adamopoulos S,Parissis JT,Paraskevaidis I,Karatzas D,Livanis E,Georgiadis M,Karavolias G,Mitropoulos D,Degiannis D,Kremastinos DT

更新日期：2003-12-01 00:00:00

abstract：:The aim of this study was to determine whether sudden cardiac death from pulmonary embolism exhibits any chronobiological rhythm. Five hundred and seven consecutive subjects dying suddenly outside of hospital and brought into our Emergency Department from January 1983 to December 1989 were studied. The time and date o...

journal_title：European heart journal

authors： Gallerani M,Manfredini R,Ricci L,Grandi E,Cappato R,Calò G,Pareschi PL,Fersini C

更新日期：1992-05-01 00:00:00

abstract：:The duration of the reduction of mortality after coronary artery bypass grafting (CABG) is an important issue and this study was undertaken to evaluate time in relation to excess mortality among CABG patients compared with the general population. Survival was analysed in 4661 patients who had undergone their first iso...

journal_title：European heart journal

authors： Ståhle E,Bergström R,Holmberg L,Edlund B,Nyström SO,Sjögren I,Hansson HE

更新日期：1994-09-01 00:00:00

abstract：:In single vessel disease angioplasty can replace surgery in the majority of patients. In cases of recurrence at the site of angioplasty or in the case of progression elsewhere, a second intervention can be performed. Thus, in the majority of patients surgery can be replaced; in the minority it can be delayed. In patie...

journal_title：European heart journal

authors： Kaltenbach M

更新日期：1987-09-01 00:00:00

abstract：:Twelve patients with the long QT syndrome were studied to determine the usefulness of 123I-metaiodobenzylguanidine (MIBG) single-photon emission tomography (SPECT) at 2 h and 6 h after injection; the results were compared to 10 healthy volunteers (controls). Uptake of MIBG in the left ventricle at 2 h after injection ...

journal_title：European heart journal

authors： Müller KD,Jakob H,Neuzner J,Grebe SF,Schlepper M,Pitschner HF

更新日期：1993-03-01 00:00:00

abstract：AIM:Previous studies have reported lifestyle and risk factor deterioration following completion of a cardiac rehabilitation program (CRP). We report the results of a one-year Extensive Lifestyle Management Intervention (ELMI) aimed at preventing these adverse changes. METHODS AND RESULTS:A total of 302 men and women w...

journal_title：European heart journal

authors： Lear SA,Ignaszewski A,Linden W,Brozic A,Kiess M,Spinelli JJ,Haydn Pritchard P,Frohlich JJ

更新日期：2003-11-01 00:00:00

abstract：:Twenty-nine men with chronic stable angina pectoris were investigated using stress electrocardiography (ECG) and stress transthoracic echocardiography by means of transoesophageal stimulation of the left atrium. At rest and after each stimulated frequency, ECG and 2-dimensional echocardiography combined with Doppler w...

journal_title：European heart journal

authors： Meluzín J,Novák M,Julínek J,Rihácek I,Urbánek D,Koukalová H,Toman J

更新日期：1993-10-01 00:00:00

abstract：AIMS:Nuclear receptors and their cofactors regulate key pathophysiological processes in atherosclerosis development. The transcriptional activity of these nuclear receptors is controlled by the nuclear receptor corepressors (NCOR), scaffolding proteins that form the basis of large corepressor complexes. Studies with pr...

journal_title：European heart journal

authors： Oppi S,Nusser-Stein S,Blyszczuk P,Wang X,Jomard A,Marzolla V,Yang K,Velagapudi S,Ward LJ,Yuan XM,Geiger MA,Guillaumon AT,Othman A,Hornemann T,Rancic Z,Ryu D,Oosterveer MH,Osto E,Lüscher TF,Stein S

更新日期：2020-03-01 00:00:00

abstract：:The effects of flosequinan and enalapril on exercise capacity (bicycle exercise duration), quality-of-life symptomatology (visual analogue scales) and New York Heart Association (NYHA) grading, were compared in 61 patients with chronic heart failure (NYHA, grade III). Bicycle exercise duration improved similarly with ...

journal_title：European heart journal

authors： Silke B,Tennet H,Fischer-Hansen J,Keller N,Heikkila J,Salminen K

更新日期：1992-08-01 00:00:00

abstract：AIMS:Three methods are used to identify dysglycaemia: fasting plasma glucose (FPG), 2-h post-load plasma glucose (2hPG) from the oral glucose tolerance test (OGTT), and glycated haemoglobin A1c (HbA1c). The aim was to describe the yield and concordance of FPG, HbA1c, and 2hPG alone, or in combination, to identify dysgl...

journal_title：European heart journal

authors： Gyberg V,De Bacquer D,Kotseva K,De Backer G,Schnell O,Sundvall J,Tuomilehto J,Wood D,Rydén L,EUROASPIRE IV Investigators.

更新日期：2015-05-14 00:00:00

abstract：:Recently published epidemiological and genetic studies strongly suggest a causal relationship of elevated concentrations of lipoprotein (a) [Lp(a)] with cardiovascular disease (CVD), independent of low-density lipoproteins (LDLs), reduced high density lipoproteins (HDL), and other traditional CVD risk factors. The ath...

journal_title：European heart journal

authors： Kostner KM,März W,Kostner GM

更新日期：2013-11-01 00:00:00

abstract：:The acute electrophysiologic effects of clinical doses of procainamide, lidocaine, metoprolol, digoxin and atropine upon the conduction of ventricular premature beats, were studied in 48 healthy volunteers. The conduction time of the first premature beat, induced 1 ms after the ventricular effective refractory period ...

journal_title：European heart journal

authors： Edvardsson N,Hirsch I,Olsson SB

更新日期：1985-01-01 00:00:00

abstract：AIMS:Assessment of N-terminal brain natriuretic peptide (NT-BNP) as a screening tool for heart failure in patients with a permanent pacemaker. METHODS AND RESULTS:Consecutive patients undergoing a routine permanent pacemaker assessment were enrolled. Patients underwent medical history and examination, echocardiography...

journal_title：European heart journal

authors： Thackray SD,Witte K,Ghosh J,Nikitin N,Anderson A,Rigby A,Goode K,Clark AL,Cleland JG

更新日期：2006-02-01 00:00:00

abstract：Aims:It has previously been demonstrated that the ratio of early mitral inflow velocity to global diastolic strain rate (E/e'sr) is a significant predictor of cardiac events in specific patient populations. The utility of this measurement to predict cardiovascular events in a general population has not been evaluated. ...

journal_title：European heart journal

authors： Lassen MCH,Biering-Sørensen SR,Olsen FJ,Skaarup KG,Tolstrup K,Qasim AN,Møgelvang R,Jensen JS,Biering-Sørensen T

更新日期：2019-02-07 00:00:00

abstract：AIMS:Aortic stenosis causes cardiac hypertrophy and fibrosis, which often persists despite pressure unloading after aortic valve replacement. The persistence of myocardial fibrosis in particular leads to impaired cardiac function and increased mortality. We investigated whether granulocyte colony-stimulating factor (G-...

journal_title：European heart journal

authors： Szardien S,Nef HM,Voss S,Troidl C,Liebetrau C,Hoffmann J,Rauch M,Mayer K,Kimmich K,Rolf A,Rixe J,Troidl K,Kojonazarov B,Schermuly RT,Kostin S,Elsässer A,Hamm CW,Möllmann H

更新日期：2012-03-01 00:00:00

abstract：AIMS:Prophylactic administration of N-acetylcysteine (NAC) (600mg orally twice daily), along with hydration, prevents contrast agent-associated nephrotoxicity (CAN) induced by a low dose of non-ionic, low-osmolality contrast dye. We tested whether a double dose of NAC is more effective to prevent CAN. METHODS AND RESU...

journal_title：European heart journal

authors： Briguori C,Colombo A,Violante A,Balestrieri P,Manganelli F,Paolo Elia P,Golia B,Lepore S,Riviezzo G,Scarpato P,Focaccio A,Librera M,Bonizzoni E,Ricciardelli B

更新日期：2004-02-01 00:00:00

abstract：AIM:Little is known about the prognostic significance of silent versus symptomatic coronary artery disease (CAD) in diabetic patients. We therefore assessed the incidence of scintigraphic evidence of CAD in diabetic patients without known CAD and the impact of symptoms and scintigraphic findings on prognosis. METHODS ...

journal_title：European heart journal

authors： Zellweger MJ,Hachamovitch R,Kang X,Hayes SW,Friedman JD,Germano G,Pfisterer ME,Berman DS

更新日期：2004-04-01 00:00:00

abstract：Aims:The burden of cardiovascular disease is increasing worldwide, which has to be reflected by cardiovascular (CV) research in Europe. CardioScape, a FP7 funded project initiated by the European Society of Cardiology (ESC), identified where CV research is performed, how it is funded and by whom. It could be transforme...

journal_title：European heart journal

authors： Pries AR,Naoum A,Habazettl H,Dunkel M,Preissner R,Coats CJ,Tornada A,Orso F,Van de Werf F,Wood DA,CardioScape steering committee.,Van de Werf F,Wood DA,O'Kelly S,Craven J,Coats A,Sipido K,De Backer D,Wallentin L,Has

更新日期：2018-07-01 00:00:00

abstract：AIMS:Right ventricular dysfunction (RVD) is an important determinant of functional status and survival in various diseases states. Data are sparse on the epidemiology and outcome of patients with severe RVD. This study examined the characteristics, aetiology, and survival of patients with severe RVD. METHODS AND RESUL...

journal_title：European heart journal

authors： Padang R,Chandrashekar N,Indrabhinduwat M,Scott CG,Luis SA,Chandrasekaran K,Michelena HI,Nkomo VT,Pislaru SV,Pellikka PA,Kane GC

更新日期：2020-03-21 00:00:00

abstract：AIMS:Hitherto, sudden cardiac death in children (SCDc)-defined as sudden cardiac death (SCD) in the 1-18 years old-has been incompletely described in the general population. Knowledge on incidence rates, causes of death and symptoms prior to death is sparse and has been affected by reporting and referral bias. METHODS...

journal_title：European heart journal

authors： Winkel BG,Risgaard B,Sadjadieh G,Bundgaard H,Haunsø S,Tfelt-Hansen J

更新日期：2014-04-01 00:00:00