Central Register of Objections for Deceased Donation in Poland 1996 to 2014: The Country With an Opting-Out System.

Abstract:

BACKGROUND:Organ, tissue, and cell procurement from deceased donors for transplantation requires consent and authorization, documented donor's positive acceptance, or lack of objection to donation expressed while alive (consent). It also requires the fulfillment of other legal conditions required by law, such as person's legal abilities to act in this field or to obtain approval for donation (authorization). Consent to and authorization of donation from deceased donors requires regulations at the national level. Poland developed an opting-out policy with the Transplantation Act in 1996. The Central Register of Objections (CRO) was introduced on November 1, 1996. The purpose of this article is a formal analysis of all submitted objections and objection withdrawals managed by the CRO since the introduction of the registry in 1996 until the end of 2014. MATERIALS AND METHODS:All data collected by the CRO during 18 years of service was subject to analysis. The objections and withdrawals of objections are summarized in the tables, along with the age, sex, and place of residence of the registered residents. RESULTS:By December 31, 2014, a total of 29,288 records were registered, including 29,013 registered objections and 275 registered withdrawals of objections; this means that 0.075% of the country's population expressed objection to posthumous tissue and organ donation for transplantation. Legal representatives submitted 4208 declarations (15.6% of all declarations). The largest inflow of objections took place in 1997, the first full year of CRO activity. CONCLUSION:CRO is an indispensable option in a country with opt-out system as a part of organ donation authorization protocol. Number of registered objections is extremely low, in practice, this leads to a situation where the will of the deceased most often is obtained from his family.

journal_name

Transplant Proc

authors

Malanowski P,Antoszkiewicz K,Jakubowska-Winecka A,Czerwiński J,Danielewicz R

doi

10.1016/j.transproceed.2016.01.057

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

1337-40

issue

5

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(16)00314-6

journal_volume

48

pub_type

杂志文章
  • Effect of blood product transfusion-induced tolerance on incidence of cardiac allograft rejection.

    abstract:BACKGROUND:Blood product transfusion has been successfully used in solid-organ transplantation to induce tolerance. Whether a similar protective effect of blood product transfusion exists in heart transplantation is controversial. OBJECTIVE:To investigate the effect of cellular blood product transfusion within 2 weeks...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2010.05.167

    authors: Kotter JR,Drakos SG,Horne BD,Hammond EH,Stehlik J,Bull DA,Reid BB,Gilbert EM,Everitt M,Alharethi R,Budge D,Verma DR,Li DY,Kfoury AG

    更新日期:2010-09-01 00:00:00

  • Transplantation of cryopreserved pancreatic islets into the portal vein.

    abstract::Pancreatic islet cells of rats obtained by the collagenase digestion method were preserved from 7 to 10 days at -80 degrees C in a deep freezer or at -196 degrees C in liquid nitrogen with Dulbecco modified Eagle's medium, supplemented with 10% or 20% DMSO (dimethyl sulfoxide); thawing was performed in a 37 degree C w...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:

    authors: Nakagawara G,Kojima Y,Mizukami T,Ono S,Miyazaki I

    更新日期:1981-06-01 00:00:00

  • Haploidentical stem cell transplantation for acute leukemia patients who experienced early relapse within one year after the first transplantation.

    abstract::To assess the safety and efficacy of allogeneic stem cell transplantation from haploidentical related donors (haplo-SCT) as 2nd transplantation for patients with early relapsed disease, we retrospectively evaluated 7 consecutive patients (median age, 42 years; range, 29-63 years) who experienced relapse within 1 year ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2014.04.011

    authors: Shimizu H,Hatsumi N,Takada S,Sakura T

    更新日期:2014-12-01 00:00:00

  • Attenuation of canine warm ischemic small bowel injury by novel combination of nitric oxide donor, FK409, and cytokine suppressive anti-inflammatory agent FR167653.

    abstract::Organ ischemia-reperfusion injury is caused by two consecutive steps, microcirculatory disturbance and neutrophil-endothelial cell interactions, which are caused by inflammatory cytokines. We examined the hypothesis that combination therapy with a donor (FK409) of nitric oxide, one of the potent mediators with diverse...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2004.08.067

    authors: Totsuka E,Murata A,Nishimura A,Umehara M,Nara M,Ono H,Nozaki T,Takiguchi M,Wajima N,Takahashi K,Seino K,Narumi S,Hakamada K,Sasaki M

    更新日期:2004-09-01 00:00:00

  • "Passing loop" technique: a new modification of the piggyback technique tailored to voluminous liver grafts--case report.

    abstract:BACKGROUND:The modified piggyback technique with side-to-side cavocavostomy decreases the risk of outflow obstruction compared with the standard piggyback method. However, this modification is not ideal for recipients who receive a graft that is voluminous or bears an enlarged caudate lobe. METHODS:We modified the inf...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2012.05.094

    authors: Eldeen FZ,Lee CF,Lee CS,Chan KM,Lee WC

    更新日期:2013-03-01 00:00:00

  • Effect of calcineurin inhibitors on low-density lipoprotein oxidation.

    abstract:INTRODUCTION:Low-density lipoprotein (LDL) oxidation is considered a key factor in the biological processes that trigger and accelerate atherosclerosis. Reported data suggest that tacrolimus improves the lipid profile in renal transplant recipients. OBJECTIVE:The objective of this study was to analyze the effect of co...

    journal_title:Transplantation proceedings

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.transproceed.2005.10.068

    authors: Cofan F,Cofan M,Campos B,Guerra R,Campistol JM,Oppenheimer F

    更新日期:2005-11-01 00:00:00

  • Rapid conversion to sirolimus for chronic progressive deterioration of the renal function in kidney allograft recipients.

    abstract::The aim of this study was to evaluate the safety of conversion to sirolimus (SRL) immunosuppression among 19 renal transplant recipients (KTX) with progressive chronic renal allograft dysfunction (CRAD). Conversion to SRL was performed with concomitant sharp withdrawal of the calcineurin inhibitor (CI). SRL was added ...

    journal_title:Transplantation proceedings

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0041-1345(03)00375-0

    authors: Citterlo F,Scatà MC,Violi P,Romagnoli J,Pozzetto U,Nanni G,Castagneto M

    更新日期:2003-06-01 00:00:00

  • Time frame of pancreas allograft rejection: an immunogenetic analysis in MHC-disparate, presensitized inbred rat strains.

    abstract:AIM:The pattern of rejection of vascularized pancreas allografts in presensitized recipients was studied among congeneic and recombinant rat strains in order to establish the time frame of rejection. Donors and recipients differed either in their entire MHC or in class I or class II MHC antigens. MATERIAL AND METHODS:...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2003.10.027

    authors: Litmathe J,Bektas H,Jörns A,Klempnauer J

    更新日期:2003-12-01 00:00:00

  • Outcome of intestinal transplants for patients with Crohn's disease.

    abstract:BACKGROUND:The pathophysiology of Crohn's disease (CD) is related to immune dysregulation making it unique among indications for intestinal transplants (ITx). We examined whether outcomes of ITx for CD are any worse than the overall ITx population. METHODS:United Network for Organ Sharing Standard Transplant Analysis ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2012.04.030

    authors: Desai CS,Khan K,Gruessner A,Gruessner R

    更新日期:2013-11-01 00:00:00

  • Individualization of immunosuppressive therapy. III. Sirolimus associated with a reduced incidence of malignancy.

    abstract:OBJECTIVE:We examined the occurrence of neoplasms among 1008 renal transplant recipients treated with a sirolimus-cyclosporine (CsA) +/- prednisone (Pred) regimen. METHODS:A comprehensive database of demographic, laboratory, clinical, and histopathologic features of these patients all followed in our transplant center...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2006.01.019

    authors: Yakupoglu YK,Buell JF,Woodle S,Kahan BD

    更新日期:2006-03-01 00:00:00

  • Specific tolerance to canine renal allografts following treatment with fractionated bone marrow and antilymphocyte serum.

    abstract::These results suggest (1) that ALS + BM fractions can be used to promote tolerance in long-term graft survivors; (2) that the presence of apparent BM cells of donor origin in the allograft in normally functioning kidneys may be related to the mechanism of allograft prolongation, and (3) that some promise of possible s...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:

    authors: Hartner WC,De Fazio SR,Markees TG,Maki T,Monaco AP,Gozzo JJ

    更新日期:1987-02-01 00:00:00

  • Steroid elimination-who, when, how?

    abstract::Steroids have numerous side effects, many occurring early posttransplantation with relatively low prednisone doses. Consequently, investigators have attempted steroid minimization or withdrawal. The first attempts at steroid minimization used early low-dose steroids and were associated with an increased rate of acute ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/j.transproceed.2008.10.007

    authors: Matas AJ

    更新日期:2008-12-01 00:00:00

  • Liver sinusoidal passenger lymphocytes reveal suppressive properties and prolong allograft survival.

    abstract::Liver sinusoidal washout cells are low responders to mitogens, and suppressive in autologous PBM, and portal blood mononuclear cells, PHA supplemented, and autologous mixed lymphocyte cultures. They are less immunogenic after IV administration into allogeneic recipients than PBM, which could be measured in an in vivo ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:

    authors: Olszewski WL,Jasklowska-Englisz M,Sadowska-Ryffa D,Lukomska B,Maksymowicz M

    更新日期:1995-02-01 00:00:00

  • Morbidity rates with reduced mycophenolate mofetil dosage: a single-center experience.

    abstract:OBJECTIVE:Mycophenolate Mofetil (MMF) is a key component of available immunosuppressant regimens for transplantation. Traditionally a dose of 2 g/d is utilized, with the incidence of side effects, most notably gastrointestinal, being well known to transplant teams. The aim of this study was to assess the incidence of s...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2006.08.170

    authors: Kaushik M,Kay MD,Bagul A,Nicholson ML

    更新日期:2006-11-01 00:00:00

  • Vaccination Against Urinary Tract Infection After Renal Transplantation.

    abstract:BACKGROUND:Recurrent urinary tract infections (UTIs) increase mortality and reduce graft survival after renal transplantation. Because current prophylactic strategies such as methionine, cranberry juice, and antibiotics fail to sufficiently prevent recurrent infections in a substantial number of patients, there is a cl...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2020.06.018

    authors: Zgoura P,Waldecker C,Bauer F,Seibert FS,Rohn B,Schenker P,Wunsch A,Hajt S,Viebahn R,Babel N,Westhoff TH

    更新日期:2020-12-01 00:00:00

  • Rehabilitation of ischemically damaged human kidneys by normothermic extracorporal hemoperfusion in situ with oxygenation and leukocyte depletion.

    abstract::The potential use of donors after cardiac death is an important issue. The crucial point in uncontrolled donors after cardiac death is the warm ischemic time. Definition of the limit of warm ischemic time was 1 of our tasks; an other was to develop a preservation protocol. Five uncontrolled donors kidneys with warm is...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2010.01.071

    authors: Reznik O,Bagnenko S,Skvortsov A,Ananyev A,Senchik K,Loginov I,Moysyuk Y

    更新日期:2010-06-01 00:00:00

  • Ischemic preconditioning improves rat kidney graft function after severe ischemia/reperfusion injury.

    abstract:UNLABELLED:Ischemic preconditioning (IP) has been shown to ameliorate renal ischemia reperfusion injury. Using a rat kidney transplantation model we determined if IP improves graft function after prolonged cold storage. MATERIALS AND METHODS:Syngeneic rat kidneys were divided into two groups. Prior to 42 hours of cold...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2004.12.274

    authors: Fuller TF,Freise CE,Feng S,Niemann CU

    更新日期:2005-01-01 00:00:00

  • Beta-2-microglobulin level predicts outcome following autologous hematopoietic stem cell transplantation in patients with multiple myeloma.

    abstract::Despite the widespread use of high-dose therapy combined with autologous hematopoietic stem cell transplantation (autoHSCT), the outcomes of multiple myeloma (MM) treatment remain variable. The aim of this study was to define pretransplantation factors that influence outcomes following autoHSCT in patients with MM. Ei...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2007.08.052

    authors: Stella-Holowiecka B,Czerw T,Holowiecka-Goral A,Giebel S,Wojnar J,Holowiecki J

    更新日期:2007-11-01 00:00:00

  • Anesthesia for ventricular assist device placement in pediatric patients: experience from a single center.

    abstract:BACKGROUND:The use of a ventricular assist device (VAD) as a bridge to heart transplantation in the pediatric population has evolved over the past decades This article presents our institution's clinical experience in the anesthetic management of pediatric patients with end-stage heart failure who underwent implantatio...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2013.02.068

    authors: Kocabas S,Askar FZ,Yagdi T,Engin C,Ozbaran M

    更新日期:2013-04-01 00:00:00

  • The effect of HBsAg-positivity of kidney donors on long-term patient and graft outcome.

    abstract::The number of patients on the kidney waiting list is increasing, creating a shortage of donor organs. To solve this problem, there is an interest in transplanting organs formerly considered marginal or undesirable. We performed seven (four living related, three cadaveric) kidney transplants from hepatitis B surface an...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2005.10.094

    authors: Berber I,Aydin C,Yigit B,Turkmen F,Titiz IM,Altaca G

    更新日期:2005-12-01 00:00:00

  • Analysis of late operations in transplant patients.

    abstract:OBJECTIVE:The charts of 174 consecutive patients were analyzed for incidence, etiology, and outcome of late operations (1 month or more posttransplant) following liver (OLT), kidney (KT), or pancreas-kidney (SPK) transplantation. MATERIALS AND METHODS:Clinical and demographic data were analyzed by chi-square analysis ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2004.11.002

    authors: Merhav H,Eisner S,Nakache R

    更新日期:2004-12-01 00:00:00

  • Excellent long-term results in de novo renal transplant recipients treated with proliferation signal inhibitors and reduced calcineurin inhibitors exposure.

    abstract:BACKGROUND:A new class of immunosuppressants, proliferation signal inhibitors (PSI)--sirolimus and everolimus--has the potential to prevent chronic allograft nephropathy (CAN). This retrospective analysis reports a 6-year practice using PSI at a single center, comparing a regimen based on reduced-dose calcineurin inhib...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2008.05.047

    authors: Carmellini M,Collini A,Ruggieri G,Garosi G,Bernini M

    更新日期:2008-07-01 00:00:00

  • Duration of brain death and cold ischemia time, but not warm ischemia time, increases expression of genes associated with apoptosis in transplanted kidneys from deceased donors.

    abstract::Apoptosis is one of the most important mechanisms leading to kidney graft injury during transplantation. The aim of this study was to assess the expression of genes involved in apoptosis in transplanted kidneys derived from deceased donors (DD) at various stages of the transplant procedure, seventy eight transplanted ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2011.08.013

    authors: lznerowicz A,Chudoba P,Kamińska D,Kościelska-Kasprzak K,Drulis-Fajdasz D,Hałoń A,Janczak D,Boratyńska M,Klinger M,Patrzałek D,Polak WG

    更新日期:2011-10-01 00:00:00

  • Solid Organ Transplantation in HIV+ Recipients: Italian Experience.

    abstract:INTRODUCTION:According to current estimates, there are about 540,000 patients who are infected with HIV in Western Europe, of which about 3100 are potential candidates for organ transplantation. In Italy, there are currently 85 HIV patients on the transplant list. METHODS:Organ transplantation activity in HIV recipien...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2015.12.049

    authors: Morabito V,Grossi P,Lombardini L,Ricci A,Trapani S,Peritore D,Gaeta A,Ballanti D,Del Sordo E,Rizzato L,Nanni Costa A

    更新日期:2016-03-01 00:00:00

  • Adipokines and nutritional status in kidney transplant recipients.

    abstract:BACKGROUND:Obesity and disturbances of adipokine concentrations are often recognized in kidney transplant recipients (KTRs). Leptin plays a key role in regulating energy intake and expenditure, including appetite and hunger, metabolism, and behavior. Adiponectin modulates certain metabolic processes, including glucose ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2014.09.014

    authors: Małgorzewicz S,Dębska-Slizień A,Czajka B,Rutkowski B

    更新日期:2014-10-01 00:00:00

  • Effect of routine insertion of a double-J stent after living related renal transplantation.

    abstract::It is still not clear whether double-J stents (DJS) are of benefit. We sought to determine whether routine prophylactic use of DJS reduced postoperative complications after renal transplantation. We prospectively evaluated 42 living donor renal transplantations performed between September 2001 and September 2003. The ...

    journal_title:Transplantation proceedings

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.transproceed.2005.01.083

    authors: Moray G,Yagmurdur MC,Sevmis S,Ayvaz I,Haberal M

    更新日期:2005-03-01 00:00:00

  • Development of the National Kidney Transplantation Program in Uruguay.

    abstract::The first kidney transplantation (KT) in Uruguay was performed in 1969. We report the rates of KT and survival of patients and grafts up to December 2014. The country has a surface of 176,215 km(2) and a population of 3,286,314 inhabitants (18.6 inhabitants per km(2)). Till December 31, 2014, 1,940 KT have been perfor...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2015.09.001

    authors: González-Martínez F,Orihuela S,Alvarez I,Dibello N,Curi L,Nin M,Wimber E,Mizraji R,Bengochea M,González G,Manzo L,Toledo R,Silva W,Chopitea Á,Lopez D,Balboa O,Porto D,Noboa O

    更新日期:2015-10-01 00:00:00

  • Stability of Organ Donor Designations on Driver's Licenses.

    abstract:BACKGROUND:Little is known about the stability of decisions that people make to be organ donors. We sought to determine the rate of stability of organ donor designations on driver's licenses. METHODS:With the use of a cross-sectional study design, we reviewed the health records of 2500 randomly selected primary-care p...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2016.04.008

    authors: Sehgal NK,Sullivan C,Figueroa M,Pencak JA,Thornton JD

    更新日期:2016-07-01 00:00:00

  • Enzymatic and morphological evaluation of the hepatic cytoprotective effect of somatostatin and octreotide during extended experimental liver preservation.

    abstract::Cytoprotective effects on the liver of somatostatin (ST) and octreotide (OT) have been previously described in normothermic ischemia-reperfusion models. The purpose of this study was an enzymatic and morphological assessment of hepatic cytoprotective effects during extended cold storage. Rat livers were washed in situ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2007.06.008

    authors: Cascales-Sanchez P,Tomas-Gomez A,Fernandez-Cornejo V,Terol-Calpena F,Sanchez-Del Campo F

    更新日期:2007-09-01 00:00:00

  • Bupropion reduces the inflammatory response and intestinal injury due to ischemia-reperfusion.

    abstract::Intestinal ischemia-reperfusion (I/R) causes severe organ failure and intense inflammatory responses, which are mediated in part by the cytokine tumor necrosis factor-alpha (TNF-alpha). Bupropion is an antidepressant known to inhibit TNF-alpha production. We sought to examine the protective effects of bupropion on int...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2013.04.010

    authors: Cámara-Lemarroy CR,Guzmán-de la Garza FJ,Cordero-Pérez P,Alarcón-Galván G,Ibarra-Hernández JM,Muñoz-Espinosa LE,Fernández-Garza NE

    更新日期:2013-07-01 00:00:00