Abstract:
:Peroxidation of lipoproteins has received attention recently in connection with its possible initiation and propagation of atherosclerosis. We studied indices of lipid peroxidation in plasma of 30 patients with either hypercholesterolemia or both hypercholesterolemia and hypertriglyceridemia, and compared them with those of 19 healthy subjects. In the patients lipid hydroperoxides measured both iodometrically and as thiobarbituric acid-reactive substances (TBA-RS) were significantly increased, while concentrations of thiol groups remained unchanged. There was no correlation between concentrations of hydroperoxides and TBA-RS, possibly because the two methods assessed different breakdown products of lipid peroxidation. Lipid hydroperoxide levels, but not those of TBA-RS were correlated with LDL-cholesterol and triglyceride levels. In 6 patients administration of vitamin E at a daily dosage of 300 mg for 4 to 6 weeks depressed elevated hydroperoxides by 33%, and TBA-RS by 44% on average.
journal_name
Wien Klin Wochenschrjournal_title
Wiener klinische Wochenschriftauthors
Domagała B,Hartwich J,Szczeklik Asubject
Has Abstractpub_date
1989-06-09 00:00:00pages
425-8issue
12eissn
0043-5325issn
1613-7671journal_volume
101pub_type
杂志文章abstract:BACKGROUND:This study aims to answer the question to which extent even very heavy nicotine-dependent smokers can benefit from a 3-week inpatient smoking cessation program. A particular focus lies on analyzing the positive effects, which go above and beyond normally anticipated health benefits. METHODS:This is a descri...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-015-0820-9
更新日期:2015-10-01 00:00:00
abstract::Primary endoscopic removal of bile duct stones is an established method of treatment. However, the extraction of stones is impossible in about 10% of cases despite successful endoscopic papillotomy and manual lithotripsy. Over a period of two years extracorporeal shock-wave lithotripsy (ESWL) was performed in 32 patie...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1989-09-29 00:00:00
abstract::There is currently no accepted therapeutic regimen for patients with chronic hepatitis C who failed to respond to standard combination treatment with interferon-alpha plus ribavirin. We investigated triple combination treatment with induction dosing of interferon-alpha plus ribavirin plus amantadine in these difficult...
journal_title:Wiener klinische Wochenschrift
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1007/BF03217706
更新日期:2004-08-31 00:00:00
abstract::Rapid scientific progress in the fields of prenatal diagnostics, obstetrics and neonatology has enabled severe malformations and hereditary diseases to be detected at a very early fetal stage and has also led to the survival of very immature newborn infants in increasing numbers. Parents, doctors and nurses must all p...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVE:Is the documentation of blood utilisation, as demanded in the guidelines of serology and transfusion medicine, a proper instrument of quality control for the use of homologous blood saving techniques? PATIENTS AND METHODS:We analysed retrospectively a list of blood utilisation based on 12,482 surgical proced...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:2000-09-29 00:00:00
abstract:BACKGROUND AND AIMS:The impact of hemodialysis on liver stiffness is still unclear. The aim of the study was to assess liver fibrosis by real-time two-dimensional shear wave elastography (RT 2D-SWE) and to quantify the influence of net fluid withdrawal on liver stiffness during one hemodialysis session. The second aim ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-019-01577-w
更新日期:2019-11-28 00:00:00
abstract::We report on a 64-year-old patient with a recurrent endometrial carcinoma which was associated with disseminated intravascular coagulation (DIC) and excessive hyperfibrinolysis. The patient presented with severe bleeding due to hypofibrinogenemia. Fibrin degradation products were excessively elevated and there were al...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1998-01-30 00:00:00
abstract::Brucellosis remains a problem in many rural areas of Greece. A case report is given of 50 patients with brucellosis treated at the regional hospital of an endemic area. Various forms of fever were observed; a raised temperature was universal. Sweating and joint pains were prominent general symptoms. The most common lo...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1977-01-21 00:00:00
abstract::The increasing scarcity of available, and finite, health care resources, and the increased demands for health care, have made consideration of effectiveness and cost-effectiveness of health care services, such as the secondary prevention of heart disease, an imperative. There is considerable evidence that modification...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1997-01-01 00:00:00
abstract:INTRODUCTION:Ephedrine or ephedra herbal products have occasionally been used to enhance sports performance and energy or to aid weight loss. The most serious side effects are those on cardiovascular function, including acute myocardial infarction, severe hypertension, myocarditis and lethal cardiac arrhythmias. CASE ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-006-0655-5
更新日期:2006-09-01 00:00:00
abstract::Thrombolytic therapy in acute ischemic stroke is safe and effective in a defined subgroup of stroke patients. Until now, different fibrinolytic substances including urokinase, streptokinase and recombinant tissue plasminogen activator (rt-PA) have been tested regarding safety, efficacy, dosage and economic parameters ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1997-10-31 00:00:00
abstract::In an autopsy series on 25 newborn infants who died in the perinatal period (19 with and 6 without respiratory distress syndrome [RDS]) the total phospho-lipid, lecithin, and sphingomyelin content was determined in lung homogenates as parameters of the surfactant content. Histologically, the newborn infants with RDS w...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1976-09-17 00:00:00
abstract::Clinical and genetic investigations were performed on seven members of a family suffering from multiple hereditary fibromatosis. These studies indicate that the responsible gene appears to be coupled and transmitted with that of the rhesus system, located at chromosome one. The diagnosis, differential diagnosis and th...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1976-02-06 00:00:00
abstract:AIM:The aim of this study was to search rubella prevalence and compare the results with national and international data. MATERIALS AND METHODS:The presence of anti-rubella immunoglobulin G (IgG) and anti-rubella immunoglobulin M (IgM) antibodies were studied in the sera obtained from cases with fever in last week and ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-013-0378-3
更新日期:2013-07-01 00:00:00
abstract::A report is presented of the course of a case of the myelodysplastic syndrome which transformed after 16 months into Philadelphia chromosome-negative chronic granulocytic leukaemia. Such a transformation into the myeloproliferative syndrome is considered to be a rare event and some views on the mechanism of this metam...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1985-03-29 00:00:00
abstract::This paper presents the results of a combined endoscopic-surgical approach with management of acute biliary pancreatitis in 91 patients. The diagnosis was always made by means of endoscopic-retrograde cholangiography. Papillary or bile duct stones, or unmistakable signs of previous stone passage, and in exceptional ca...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::In end stage congestive heart failure activation of a series of compensatory mechanisms increase renal vascular resistance and impair renal function. Prostaglandin E1 is increasingly used in the treatment of severe heart failure for its vasodilating actions. In various experimental settings prostaglandin E analogues a...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1998-07-31 00:00:00
abstract::Over the past years there has been great interest in developing diagnostic typologies of married couples undergoing therapy. 92 couples admitted to therapy were asked to fill out the Giessen test, a test widely used for diagnosis in marital therapy. The method of cluster analysis was used to find a classification. The...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1983-07-08 00:00:00
abstract::The lipid-reducing effects of bezafibrate and clofibrate were investigated in a double-blind crossover trial. 3 x 200 mg/d bezafibrate and 3 x 500 mg/d clofibrate were administered for periods of 8 weeks each to 22 patients with primary hyperlipoproteinaemia (9 Type IIb, 13 Type IV). Placebo periods preceded and follo...
journal_title:Wiener klinische Wochenschrift
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1980-02-01 00:00:00
abstract::The indications for operative treatment of prostatic adenomas are outlined. The three operative techniques (suprapubic adenomectomy, resection and cryosurgery) should not be considered rival procedures, but complementary methods of therapy. The postoperative mortality dropped from 5.64% in the years 1957-1967 to 1.01%...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1978-03-17 00:00:00
abstract::This paper reports the first Austrian case of infantile nemaline myopathy in a girl aged 19 years, presenting with congenital skeletal dysplasia, reduced body weight and slowly progressive limb girdle muscular atrophy, myopathic face and difficulty in swallowing. Electromyography revealed a combination of myopathic an...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1988-06-10 00:00:00
abstract::Contrast media induced nephropathy is a common complication, particularly in high risk patients, such as patients with chronic kidney disease (CKD) and diabetes. The majority of studies show an increased in-hospital mortality and an unfavourable long-term prognosis after manifestation of contrast media induced nephrop...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:10.1007/s00508-009-1145-3
更新日期:2009-01-01 00:00:00
abstract::The identification of basal cells by the basal-cell-specific anti-cytokeratin antibody 34 beta E12 has been shown to be useful in the diagnosis of prostate carcinoma. To determine the usefulness of 34 beta E12 in prostate biopsies we examined formalin-fixed needle biopsy specimens. In a 17-month period 796 prostate ne...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1998-09-18 00:00:00
abstract:BACKGROUND AND PURPOSE:The aim of this retrospective study was to determine in-hospital mortality and morbidity secondary to intracerebral hemorrhage and to analyse variables considered to be significantly associated with survival in these patients. PATIENTS AND METHODS:The study cohort consisted of 135 consecutive pa...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:2000-02-25 00:00:00
abstract::In this study 36 patients with cardiac phobia were examined prior to hospitalisation and 29 of them were re-examined after 2.5 years. An analysis of the clinical pictures showed that all of the patients met the DSM III criteria for panic disorder. The follow-up results indicated that the anxiety attacks often recurred...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1987-08-28 00:00:00
abstract::Prostaglandins (PG) play an important role in the regulation of the renal blood flow and glomerular filtration rate. This study was designed to examine PG synthesis in the presence and absence of the ACE inhibitor captopril, PG binding to specific receptors and the ability of PG to stimulate cAMP accumulation in isola...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::Two major features of atherosclerosis may be distinguished: (a) atherosis caused by lipid infiltration in cells and extracellularly and (b) sclerosis caused by connective tissue deposition and by functional disturbance of the endothelium, leading to impairment of endothelium-derived relaxing factor (EDRF)-release and ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:An association between malnutrition, weight loss and mortality has been demonstrated in patients with chronic obstructive pulmonary disease (COPD), but the prognostic influence of low body-mass index (BMI) and plasma concentrations of albumin and cholesterol is less clear in patients with chronic respiratory ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-004-0226-6
更新日期:2004-09-30 00:00:00
abstract::In 44 patients with biliary obstructions, percutaneous transhepatic cholangioscopy (PTCS) was performed during percutaneous transhepatic biliary drainage procedures (PTCD). In all patients the obstruction could be decompressed via the PTCD sufficiently. 30 of these cases who had PTCS showed suspect hepatic and pancrea...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::Madelung's disease, or multiple symmetric lipomatosis, is an extremely rare disease and very likely to be under-diagnosed. It is characterized by multiple symmetrical non-encapsulated fat accumulations mainly located around the neck, shoulders, upper extremities and upper parts of the trunk. The disorder predominantly...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-011-0045-5
更新日期:2012-03-01 00:00:00