当前位置： SCI文献检索 > Photodiagnosis and Photodynamic Therapy期刊下所有文献 > Diagnostic accuracy of optical coherence tomography in actinic keratosis and basal cell carcinoma.

Diagnostic accuracy of optical coherence tomography in actinic keratosis and basal cell carcinoma.

Abstract：

BACKGROUND:Early diagnosis of non-melanoma skin cancer (NMSC) is potentially possible using optical coherence tomography (OCT) which provides non-invasive, real-time images of skin with micrometre resolution and an imaging depth of up to 2mm. OCT technology for skin imaging has undergone significant developments, improving image quality substantially. The diagnostic accuracy of any method is influenced by continuous technological development making it necessary to regularly re-evaluate methods. OBJECTIVE:The objective of this study is to estimate the diagnostic accuracy of OCT in basal cell carcinomas (BCC) and actinic keratosis (AK) as well as differentiating these lesions from normal skin. METHODS:A study set consisting of 142 OCT images meeting selection criterea for image quality and diagnosis of AK, BCC and normal skin was presented uniformly to two groups of blinded observers: 5 dermatologists experienced in OCT-image interpretation and 5 dermatologists with no experience in OCT. During the presentation of the study set the observers filled out a standardized questionnaire regarding the OCT diagnosis. Images were captured using a commercially available OCT machine (Vivosight ®, Michelson Diagnostics, UK). RESULTS:Skilled OCT observers were able to diagnose BCC lesions with a sensitivity of 86% to 95% and a specificity of 81% to 98%. Skilled observers with at least one year of OCT-experience showed an overall higher diagnostic accuracy compared to inexperienced observers. CONCLUSIONS:The study shows an improved diagnostic accuracy of OCT in differentiating AK and BCC from healthy skin using state-of-the-art technology compared to earlier OCT technology, especially concerning BCC diagnosis.

journal_name

Photodiagnosis Photodyn Ther

journal_title

Photodiagnosis and photodynamic therapy

authors

Olsen J,Themstrup L,De Carvalho N,Mogensen M,Pellacani G,Jemec GB

doi

10.1016/j.pdpdt.2016.08.004

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

44-49

eissn

1572-1000

issn

1873-1597

pii

S1572-1000(16)30103-X

journal_volume

16

pub_type

杂志文章

相关文献

Photodiagnosis and Photodynamic Therapy文献大全
  • An investigation of the fluorescence induced by topical application of 5-aminolaevulinic acid and methyl aminolaevulinate at different body sites on normal human skin.

    abstract：BACKGROUND:Although discovered over a century ago it is only in the last 25 years that photodynamic therapy (PDT) has been the focus of intense research. This versatile treatment modality has been shown to be effective in treating a wide variety of malignancies, and with the increasing incidence of non-melanoma skin ca...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2010.12.004

    authors： Lesar A,Ferguson J,Moseley H

    更新日期：2011-06-01 00:00:00

  • Photodynamic inactivation of methicillin-resistant Staphylococcus aureus on skin using a porphyrinic formulation.

    abstract：:Staphylococcus aureus is responsible for skin and soft tissue infections. Having in mind increased antibiotic resistance, in this study the efficacy of antimicrobial photodynamic therapy (aPDT) with a porphyrinic formulation (FORM) as photosensitizer (PS) to photoinactivate methicillin-resistant Staphylococcus aureus ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101754

    authors： Braz M,Salvador D,Gomes ATPC,Mesquita MQ,Faustino MAF,Neves MGPMS,Almeida A

    更新日期：2020-06-01 00:00:00

  • Effect of mechanical debridement with adjunct antimicrobial photodynamic therapy in the treatment of peri-implant diseases in type-2 diabetic smokers and non-smokers.

    abstract：OBJECTIVE:The aim of the present 6-month follow-up study was to assess the effect of mechanical debridement (MD) with adjunct antimicrobial photodynamic therapy (aPDT) in the treatment of peri-implant diseases in type-2 diabetic smokers and non-smokers. METHODS:Patients were divided into 2 groups: (a) Group-1: type-2 ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2016.11.005

    authors： Abduljabbar T

    更新日期：2017-03-01 00:00:00

  • Photodynamic therapy in wound healing in vivo: a systematic review.

    abstract：:Wounds constitute severe problems in public health. Inappropriate manipulation to promote wound healing and indiscriminate use of antibiotics may contribute to failure in wound treatment, leading to bacterial growth and resistance. Appropriate and correct approaches to wound treatment are crucially important. Further,...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101682

    authors： Oyama J,Fernandes Herculano Ramos-Milaré ÁC,Lopes Lera-Nonose DSS,Nesi-Reis V,Galhardo Demarchi I,Alessi Aristides SM,Juarez Vieira Teixeira J,Gomes Verzignassi Silveira T,Campana Lonardoni MV

    更新日期：2020-06-01 00:00:00

  • Evaluation of the progression rate of atrophy lesions in punctate inner choroidopathy (PIC) based on autofluorescence analysis.

    abstract：PURPOSE:To investigate the autofluorescence (AF) characteristics of punctate inner choroidopathy (PIC) and to evaluate the progression rate of retinal pigment epithelium (RPE) atrophy lesions in PIC using confocal scanning laser ophthalmoscopy. METHODS:Twenty-two eyes of 14 PIC cases and 21 eyes of 21 non-proliferativ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2014.07.002

    authors： Hua R,Liu L,Chen L

    更新日期：2014-12-01 00:00:00

  • Cost effective and efficient screening of tuberculosis disease with Raman spectroscopy and machine learning algorithms.

    abstract：:The current study presents Raman Spectroscopy (RS) accompanied by machine learning algorithms based on Principle Component Analysis (PCA) and Hierarchical Cluster Analysis (HCA) for analysis of tuberculosis (TB). TB positive (diseased), TB negative (cured) and control (healthy) serum samples are considered for inter a...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101963

    authors： Ullah R,Khan S,Chaudhary II,Shahzad S,Ali H,Bilal M

    更新日期：2020-12-01 00:00:00

  • Circumscribed choroidal hemangioma associated with choroidal neovascularization in a HIV-infected case: photodynamic therapy and intravitreous ranibizumab.

    abstract：:Circumscribed choroidal hemangioma (CCH) is rarely associated with choroidal neovascularization (CNV), especially in HIV-infected patients. And the therapy is still controversial. In this study, we discussed the mechanism, clinical feature and treatment of such lesions, based on multi-modality imaging evidences. Photo...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2014.04.005

    authors： Hua R,Zhao N,Hu Y,Zhang CM,Chen L

    更新日期：2014-09-01 00:00:00

  • Comparison of 5-aminolevulinic acid photodynamic therapy and red light for treatment of photoaging.

    abstract：OBJECTIVE:The aim of this pilot study was to compare the efficacy of ALA-PDT and red light alone in the treatment of photoaging. METHODS:A total of 14 adults with photoaging skin were recruited. ALA-PDT or red light alone was applied to the forearm extensor. Before and after treatment, the treated sites were examined ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2014.02.007

    authors： Ji J,Zhang LL,Ding HL,Wang HW,Huang Z,Wang XX,Wang PR,Wang XL

    更新日期：2014-06-01 00:00:00

  • Vascular targeted photodynamic therapy for bleeding gastrointestinal mucosal vascular lesions: a preliminary study.

    abstract：BACKGROUND:Vascular-targeted photodynamic therapy (V-PDT) has shown good selectivity and efficacy in the treatment of certain types of vascular disease, including port wine stains, age-related macular degeneration, and esophageal varices. This study was conducted to test the efficacy and safety of V-PDT in the treatmen...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2011.11.003

    authors： Qiu H,Mao Y,Gu Y,Wang Y,Zhu J,Zeng J

    更新日期：2012-06-01 00:00:00

  • Lesion oxygenation associates with clinical outcomes in premalignant and early stage head and neck tumors treated on a phase 1 trial of photodynamic therapy.

    abstract：BACKGROUND:We report on a Phase 1 trial of photodynamic therapy (PDT) for superficial head and neck (H&N) lesions. Due to known oxygen dependencies of PDT, translational measurements of lesion hemoglobin oxygen saturation (StO2) and blood volume (tHb) were studied for associations with patient outcomes. METHODS:PDT wi...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2017.10.015

    authors： Ahn PH,Finlay JC,Gallagher-Colombo SM,Quon H,O'Malley BW Jr,Weinstein GS,Chalian A,Malloy K,Sollecito T,Greenberg M,Simone CB 2nd,McNulty S,Lin A,Zhu TC,Livolsi V,Feldman M,Mick R,Cengel KA,Busch TM

    更新日期：2018-03-01 00:00:00

  • Photodynamic therapy in the management of actinic keratosis: Retrospective evaluation of outcome.

    abstract：INTRODUCTION:Photodynamic therapy (PDT) is a minimally invasive intervention used in the management of tissue disorders. In this retrospective study, a total of 62 patients with actinic keratosis (AKs) were treated with surface illumination PDT. Comparisons with the clinical features, rate of recurrence as well as mali...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2016.04.017

    authors： Jerjes W,Hamdoon Z,Abdulkareem AA,Hopper C

    更新日期：2017-03-01 00:00:00

  • Monitoring the effectiveness of photodynamic therapy with periodic renewal of the photosensitizer on intracanal Enterococcus faecalis biofilms.

    abstract：BACKGROUND AND OBJECTIVE:Photodynamic therapy (PDT) can eliminate microorganisms in a root canal. However, the parameters for disinfection remain undefined. This study assessed the effectiveness of a PDT protocol against intracanal Enterococcus faecalis biofilms. MATERIALS AND METHODS:Root canals were contaminated wit...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2016.01.002

    authors： Soares JA,Santos Soares SMC,Santos César CA,de Carvalho MAR,Brito-Júnior M,de Sousa GR,Soares BM,de Macêdo Farias L

    更新日期：2016-03-01 00:00:00

  • Photodynamic activity and DNA binding studies of Pd@SiO2 core-shell nanoparticles in vitro.

    abstract：:Metal-semiconductor core-shell type Pd@SiO2 nanoparticles (NPs) were successfully synthesized by Stober's method and the product was characterized by UV-vis, XRD, FT-IR, SEM, HR-TEM and EDX techniques. In vitro Photodynamic activity and DNA binding studies of Pd@SiO2 core shell nanoparticles were studied. Cell viabili...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2019.03.008

    authors： Dhanalekshmi KI,Sangeetha K,Meena KS,Magesan P,Manikandan A,Jayamoorthy K

    更新日期：2019-06-01 00:00:00

  • Manual dexterity and dental biofilm accumulation in independent older adults without hand disabilities: A cross-sectional study.

    abstract：BACKGROUND:This study investigated the relationship between manual dexterity and dental biofilm accumulation in independent older Koreans using Quantitative Light-Induced Fluorescence-Digital (QLF-D). METHODS:This cross-sectional study included 44 participants recruited from senior welfare facilities in South Korea an...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.pdpdt.2018.11.007

    authors： Shin NR,Choi JS

    更新日期：2019-03-01 00:00:00

  • Treatment of verrucous carcinoma in penis with topical aminolevulinic acid photodynamic therapy: An effective and safe treatment method.

    abstract：BACKGROUND:Verrucous carcinoma of the penis is a rare disease characterized by verrucous lesions. The traditional treatment methods for verrucous carcinoma result in loss of sexual function are not satisfactory. The purpose of this study was to evaluate the safety and effect of topical aminolevulinic acid photodynamic ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2018.08.015

    authors： He X,Zhang J,Tan L,Wang W,Song Y,Wang H,Zhang X,Kou H,Lu Y

    更新日期：2018-12-01 00:00:00

  • Comparison between the outcomes of fluorescein angiography-guided and indocyanine green angiography-guided half-time photodynamic therapy for central serous chorioretinopathy.

    abstract：BACKGROUND AND OBJECTIVES:This study aimed to compare the efficacy of fluorescein angiography (FA)-guided and indocyanine green angiography (ICGA)-guided half-time photodynamic therapy (PDT) for central serous chorioretinopathy (CSC). SUBJECTS AND METHODS:Medical records of 61 eyes of 61 CSC patients who underwent hal...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101955

    authors： Hayashida M,Miki A,Honda S,Nakamura M

    更新日期：2020-09-01 00:00:00

  • The optical imaging of idiopathic paracentral acute middle maculopathy in a Chinese young man and review of the literature.

    abstract：:We report a case of idiopathic paracentral acute middle maculopathy with typical optical imaging and clinical features. A 26-year-old Chinese policeman presented with a 20-day history of paracentral scotoma in the left eye after early wake-up and long-time working in front of computer the day before. He experienced su...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2017.07.004

    authors： Chen Y,Hu Y

    更新日期：2017-09-01 00:00:00

  • Taking treatment decisions in non-melanoma skin cancer--the place for topical photodynamic therapy (PDT).

    abstract：BACKGROUND:Epithelial non-melanoma skin cancer (NMSC) like actinic keratosis (AK), Bowen's disease (BD) and basal cell carcinoma (BCC) represent the most common malignancies in the fair skinned population. Epidemiological data reveal high incidences, especially for actinic keratoses, which are basically non-invasive sq...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章,评审

    doi：10.1016/j.pdpdt.2009.12.004

    authors： Sidoroff A,Thaler P

    更新日期：2010-03-01 00:00:00

  • Photobiomodulation and antimicrobial photodynamic therapy for oral cytomegalovirus reactivation following acute graft-versus-host disease.

    abstract：:The relationship between cytomegalovirus (CMV), a severe complication in immunocompromised patients, and graft-versus-host disease (GVHD) has already been reported but remains without complete elucidation, especially concerning oral lesions. Considering that antimicrobial photodynamic therapy (aPDT) has an antimicrobi...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101849

    authors： Rezende SB,Campos L,Palma LF,Tateno RY,Simões A,Macedo MC,Silva RLD

    更新日期：2020-12-01 00:00:00

  • Could photodynamic therapy be utilized as a treatment modality for oral lichen planus?

    abstract：BACKGROUND:Oral lichen planus (OLP) is a chronic inflammatory disease. There is no standard treatment modality for OLP. Recently, photodynamic therapy (PDT) has been advocated as a new treatment modality for OLP. AIM:The aim of the present study is to compare the effect of PDT using methylene blue (MB) as a photosensi...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101677

    authors： Saleh W,Tageldin S,Khashaba E,Darwish M,Elnagdy S,Khashaba O

    更新日期：2020-06-01 00:00:00

  • Surgical debulking combined with photodynamic therapy to manage residual extramedullary plasmacytoma of the nasopharynx.

    abstract：:Extramedullary plasmacytomas (EMP) are rare plasma cell neoplasms that are mostly located in the mucosal surfaces of the upper aerodigestive tract. The standard treatment is radiotherapy (RT), with surgical resection reserved as salvage procedure. In this report a patient with a EMP, located in the nasopharynx and ref...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2011.03.340

    authors： Karakullukcu B,De Boer JP,Van Veen R,Wegman J,Tan B

    更新日期：2011-09-01 00:00:00

  • In vivo detection of circulating tumour cell clusters by photodiagnostic spectroscopy.

    abstract：BACKGROUND:We demonstrate a new diagnostic method, Photodiagnostic Infrared Spectroscoppy (PDIS), which is able to detect circulating tumor clusters and circulating tumor cells in the circulatory system. METHODS:The PDIS method is based on photodiagnostic physics and high resolution spectroscopy and is using calibrate...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101755

    authors： Schikora D

    更新日期：2020-06-01 00:00:00

  • Investigation of anti-inflammatory and anti-proliferative activities promoted by photoactivated cationic porphyrin.

    abstract：BACKGROUND:Photodynamic therapy (PDT) is a technique that uses light and a photosensitizer, converting local molecular oxygen into singlet oxygen, which eliminates a target unhealthy tissue. It has been increasingly used for the treatment of several diseases including skin disorders. Psoriasis is a chronic inflammatory...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2015.05.003

    authors： Carrenho LZ,Moreira CG,Vandresen CC,Gomes Junior R,Gonçalves AG,Barreira SM,Noseda MD,Duarte ME,Ducatti DR,Dietrich M,Paludo K,Cabrini DA,Otuki MF

    更新日期：2015-09-01 00:00:00

  • Potential of cationic porphyrins for photodynamic treatment of cutaneous Leishmaniasis.

    abstract：:Four tetracationic porphyrins have been investigated for their ability to photo-inactivate Leishmania major promastigotes. Parallel photocytotoxicity assays against keratinocytes and macrophages show significant differences in activity between the microorganism and mammalian cells. Results suggest that it may be possi...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2006.04.004

    authors： Bristow CA,Hudson R,Paget TA,Boyle RW

    更新日期：2006-09-01 00:00:00

  • Pharmacokinetics and biodistribution of Photolon (Fotolon) in intact and tumor-bearing rats.

    abstract：BACKGROUND:This paper provides the results of the non-clinical evaluation of biodistribution of the PS Photolon in inner organs and tissues of intact and tumor-bearing rats with xenograft tumors of different morphologic types. METHODS:The accumulation studies were performed in rats by means of intravital laser fluorim...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2009.04.002

    authors： Shliakhtsin SV,Trukhachova TV,Isakau HA,Istomin YP

    更新日期：2009-06-01 00:00:00

  • Red fluorescence of plaque in the dentition-a comparison of Quantitative Light-induced Fluorescence-Digital (QLF-D) images and conventional images of disclosed plaque.

    abstract：BACKGROUND:Quantitative Light-induced Fluorescence-Digital (QLF-D) detects red fluorescence of plaque, but is almost solely used on labial anterior tooth surfaces. As distribution and formation of plaque varies distinctly within the dentition, our aim was to investigate, how red fluorescing plaque is related to disclos...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.102063

    authors： Ganss C,Glanz A,Glanz T,Schlueter N,Ruf S

    更新日期：2020-12-01 00:00:00

  • Improving the competency of dental hygiene students in detecting dental restorations using quantitative light-induced fluorescence technology.

    abstract：OBJECTIVES:The purpose of this study was to determine the usefulness of a quantitative light-induced fluorescence (QLF) technology in detecting dental restorations by comparing the detection ability of dental hygiene students between using conventional visual inspection alone and visual inspection combined with QLF tec...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.pdpdt.2016.12.010

    authors： Oh HY,Jung HI,Lee JW,de Jong EJ,Kim BI

    更新日期：2017-03-01 00:00:00

  • Synthesis, spectral characterization, crystal structure, cytotoxicity and apoptosis-Inducing activity of two derivatives of 2-hydroxy-1,4-naphthaquinone.

    abstract：:A phenaxazone compound [5H-Benzo[a]phenoxazin-5-one (BP)] along with an aminoquinone[2-[(o-hydroxyphenyl)amino]-1,4-naphthaquinone (HAN)] derivatives were synthesized from lawsone using ultrasound irradiation technique. The structure of the compounds were characterized by elemental analysis and various spectral studie...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2017.01.180

    authors： P R KR,Fernandez A,Laila SP,B A,C S S,V S V

    更新日期：2017-03-01 00:00:00

  • Multimodal cancer cell therapy using Au@Fe2O3 core-shell nanoparticles in combination with photo-thermo-radiotherapy.

    abstract：:In this study, gold coated iron oxide nanoparticle (Au@Fe2O3 NP) was synthesized in a core-shell structure. Photothermal and radiosensitization effects of Au@Fe2O3 NPs were investigated on KB human mouth epidermal carcinoma cell line. Cell death and apoptosis were measured to study the effects of nanoparticles in comb...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2018.08.003

    authors： Hosseini V,Mirrahimi M,Shakeri-Zadeh A,Koosha F,Ghalandari B,Maleki S,Komeili A,Kamrava SK

    更新日期：2018-12-01 00:00:00

  • Effect of 5-aminolevulinic acid photodynamic therapy on the expression of apoptosis inhibitors Bcl-2 and Survivin in keratinocytes of condyloma acuminatum.

    abstract：BACKGROUND:Condyloma acuminatum is a highly infectious disease caused by the human papillomavirus. Previous studies have shown that 5-aminolevulinic acid photodynamic therapy can inhibit proliferation of condyloma acuminatum keratinocytes. However, the effect of 5-aminolevulinic acid photodynamic therapy on condyloma a...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2019.07.018

    authors： Yin G,Li X,Wang X,Zhang H

    更新日期：2019-12-01 00:00:00