当前位置： SCI文献检索 > Photodiagnosis and Photodynamic Therapy期刊下所有文献 > Vascular targeted photodynamic therapy for bleeding gastrointestinal mucosal vascular lesions: a preliminary study.

Vascular targeted photodynamic therapy for bleeding gastrointestinal mucosal vascular lesions: a preliminary study.

Abstract：

BACKGROUND:Vascular-targeted photodynamic therapy (V-PDT) has shown good selectivity and efficacy in the treatment of certain types of vascular disease, including port wine stains, age-related macular degeneration, and esophageal varices. This study was conducted to test the efficacy and safety of V-PDT in the treatment of gastrointestinal (GI) bleeding caused by the abnormal dilatation of capillaries. METHODS:Patients with bleeding GI mucosal vascular lesions treated with V-PDT were included in this retrospective study. The efficiency of V-PDT was analyzed by comparing the documented endoscopy results, hemoglobin levels, and transfusion requirements before and at 6 months after the last V-PDT. Side effects during and after V-PDT and follow-up results were also analyzed. RESULTS:Seven patients with bleeding GI mucosal vascular lesions were treated with V-PDT. After 1-4 V-PDT sessions, all patients no longer needed transfusions to maintain a stable hemoglobin level during the follow-up period of 6 months. The mean hemoglobin level of the seven patients improved from 6.21±1.48 g/dl to 11.66±1.21 g/dl (p<0.001), and the GI bleeding and melena of all the patients disappeared. No perforations, strictures, scars, or episodes of photosensitization occurred in the seven patients, and there were no recurrences of GI bleeding during the 1-21 months of further follow-up. CONCLUSIONS:This preliminary study indicated that V-PDT is a highly selective, safe, well-tolerated, and effective treatment modality for bleeding GI mucosal vascular lesions. However, prospective studies with larger sample sizes are needed to confirm this finding.

journal_name

Photodiagnosis Photodyn Ther

journal_title

Photodiagnosis and photodynamic therapy

authors

Qiu H,Mao Y,Gu Y,Wang Y,Zhu J,Zeng J

doi

10.1016/j.pdpdt.2011.11.003

subject

Has Abstract

pub_date

2012-06-01 00:00:00

pages

109-17

issue

2

eissn

1572-1000

issn

1873-1597

pii

S1572-1000(11)00450-9

journal_volume

9

pub_type

杂志文章

相关文献

Photodiagnosis and Photodynamic Therapy文献大全
  • Pivotal roles of peptide transporter PEPT1 and ATP-binding cassette (ABC) transporter ABCG2 in 5-aminolevulinic acid (ALA)-based photocytotoxicity of gastric cancer cells in vitro.

    abstract：BACKGROUND:Recently, 5-aminolevulinic acid-based photodynamic therapy (ALA-PDT) is being widely used in cancer therapy owing to the tumor-specific accumulation of photosensitizing protoporphyrin IX (PpIX) after the administration of ALA. In the present study, by focusing on genes involved in the porphyrin biosynthesis ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2011.12.004

    authors： Hagiya Y,Endo Y,Yonemura Y,Takahashi K,Ishizuka M,Abe F,Tanaka T,Okura I,Nakajima M,Ishikawa T,Ogura S

    更新日期：2012-09-01 00:00:00

  • Dissecting cellulitis of the scalp successfully treated with ALA-PDT: Case report.

    abstract：:A case of recalcitrant dissecting cellulitis of the scalp (DCS) in a 23-year-old male patient was treated with 4 times of topical ALA-PDT at intervals of 10-15 days. The patient responded well without any unbearable adverse effects and presented satisfactory effects. Before applying this therapy, the patient and his d...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2018.10.001

    authors： Zhan Y,Chen X,Zhou Y,Zou P,Xiao R

    更新日期：2018-12-01 00:00:00

  • Surgical interventions combined with photodynamic therapy in the treatment of Perifolliculitis Capitis Abscendens et Suffodiens: Report of 5 cases.

    abstract：:Perifolliculitis capitis abscedens et suffodiens (PCAS), also known as dissecting cellulitis of the scalp (DCS), is a rare, chronic, suppurative inflammatory disease of the scalp which may evolve into cicatricial alopecia. Its refractory nature has a detrimental impact on patients' quality of life. Here, we report fiv...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101660

    authors： Liu H,Ding A,Aloke G,Mvogo Ndzana LB,Wan M,Lin Y,Zhang J

    更新日期：2020-06-01 00:00:00

  • Optical discrimination of benign and malignant oral tissue using Z-scan technique.

    abstract：:A new optical method to discriminate benign and malignant oral tissue is reported. Twenty four tissue biopsy of patients tumor have been prepared in standard method without coloring process. The CW He-Ne laser beam interrogated the samples in optical setup. Linear absorption of tissues in laser wavelength measured and...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2016.08.001

    authors： Salman M,Hossein MA,Kamran KS,Shayan M

    更新日期：2016-12-01 00:00:00

  • Clinical study on clinical operation and post-treatment reactions of HMME-PDT in treatment of PWS.

    abstract：OBJECTIVE:To analyze the clinical efficacy of hematoporphyrin monomethyl ether photodynamic therapy (HMME-PDT) in treating port-wine stains (PWS), and its clinical operation skills and operation essentials. METHOD:A total of 16 cases of PWS with negative HMME skin test results were included in this study. Their treate...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章,评审

    doi：10.1016/j.pdpdt.2017.09.013

    authors： Zhang Y,Zou X,Chen H,Yang Y,Lin H,Guo X

    更新日期：2017-12-01 00:00:00

  • PDT induced bystander effect on human xenografted colorectal tumors as evidenced by sodium MRI.

    abstract：BACKGROUND:Previous in vivo studies on photodynamic therapy (PDT)-treated, high cellular density tumors showed evidences of a bystander effect accompanying the therapy, cellular death continuing beyond the limits of the photochemical reactions in time and space. This process is generated by the initially damaged cells ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2012.03.001

    authors： Poyer F,Thomas CD,Garcia G,Croisy A,Carrez D,Maillard P,Lupu M,Mispelter J

    更新日期：2012-12-01 00:00:00

  • Hyperthermia enhances the antitumor effect of photodynamic therapy with ALA hexyl ester in a squamous cell carcinoma tumor model.

    abstract：BACKGROUND:Photodynamic therapy (PDT) using 5-aminolevulinic acid is considered to be ineffective in the treatment of tumors with progression to the deep layer. Therefore, for such tumors, a method is required which can enhance the effectiveness of this therapy. We examined the anti tumor effect of the combination of P...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2012.04.003

    authors： Yanase S,Nomura J,Matsumura Y,Kato H,Tagawa T

    更新日期：2012-12-01 00:00:00

  • Antibacterial effect of S-Porphin sodium photodynamic therapy on Staphylococcus aureus and multiple drug resistance Staphylococcus aureus.

    abstract：BACKGROUND:Antibacterial photodynamic therapy (aPDT) has been proposed as an alternative strategy to inactivate bacteria. This study was designed to investigate the antibacterial effect of a novel photosensitizer S-Porphin sodium (S-PS) on plankton and biofilm cultures of Staphylococcus aureus (S. aureus) and its multi...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2019.08.031

    authors： Jia M,Mai B,Liu S,Li Z,Liu Q,Wang P

    更新日期：2019-12-01 00:00:00

  • Efficacy of lidocaine 7 %, tetracaine 7 % self-occlusive cream in reducing MAL-cPDT-associated pain in subjects with actinic keratosis: A randomized, single-blind, vehicle-controlled trial (The "3P-Trial").

    abstract：INTRODUCTION:Conventional photodynamic therapy (cPDT) is considered a very effective treatment of actinic keratosis (AK) lesions. However, its use is limited by the fact that this procedure could be very painful. The use of topical anesthetics such as tetracaine or lignocaine/prilocaine has shown disappointing results ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101758

    authors： Brumana MB,Milani M,Puviani M

    更新日期：2020-06-01 00:00:00

  • Fast elimination of onychomycosis by hematoporphyrin derivative-photodynamic therapy.

    abstract：:Onychomycosis is a fungal nail disease and is one of the major onychopathy worldwide. Topical or oral antifungal therapies are used to treat this disease, but often they are inefficient and oral medications can even cause several side effects. Photodynamic therapy (PDT) is a well established technique and hence, may r...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2013.01.001

    authors： Silva AP,Kurachi C,Bagnato VS,Inada NM

    更新日期：2013-09-01 00:00:00

  • Mitomycin C-induced cell cycle arrest enhances 5-aminolevulinic acid-based photodynamic therapy for bladder cancer.

    abstract：BACKGROUND:Photodynamic therapy (PDT) and diagnosis (PDD) using 5-aminolevulinic acid (ALA) to control the production of the intracellular photosensitizer protoporphyrin IX (PpIX) are commonly used clinically. Previously, we demonstrated that dormant and drug-induced dormancy-like cancer cells accumulated high PpIX lev...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101893

    authors： Nakayama T,Nozawa N,Kawada C,Yamamoto S,Ishii T,Ishizuka M,Namikawa T,Ogura SI,Hanazaki K,Inoue K,Karashima T

    更新日期：2020-09-01 00:00:00

  • Effect of Er,Cr:YSGG on bond strength and microleakage of dentin bonded to resin composite with different distance and irradiation time.

    abstract：BACKGROUND:To explore the surface modification of dentin using Er,Cr:YSGG phototherapy and bonding system on the shear bond strength and microleakage scores at two different distances and times of laser irradiation. MATERIALS AND METHODS:Ninety disease-free third molars were collected for the experiment. The four lase...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2018.10.017

    authors： Almojaly SA,Sulaiman Al-Hamdan R,Alrahlah A,Qutub OA,Alnajashi S,Vohra F,Abduljabbar T

    更新日期：2019-03-01 00:00:00

  • Enhanced radiosensitivity of LNCaP prostate cancer cell line by gold-photoactive nanoparticles modified with folic acid.

    abstract：BACKGROUND:Conventional cancer treatment methods suffer from many limitations such as non-specificity in discrimination between healthy and malignant cells. The aim of this study was to investigate the role of polymeric gold-photoactive nanoparticles (PGPNPs) conjugated with folic acid (FA) as theranostic nanoparticles...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2019.101602

    authors： Changizi O,Khoei S,Mahdavian A,Shirvalilou S,Mahdavi SR,Keyvan Rad J

    更新日期：2020-03-01 00:00:00

  • Influences of galactose ligand on the uptake of TADF liposomes by HepG2 cells.

    abstract：:Glucose is the main energy substance to drive the physiological events of the cell.. Malignant cells exhibit a much higher rate of glycolysis than healthy cells to relieve the increased needs of energy. The higher metabolic rate induces the over-expression of the Glucose Transporter (GLUT) to transport more glucose in...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.102014

    authors： Wang C,Chen Z,Tang X,Liu X,Na W,Li W,Liu T

    更新日期：2020-12-01 00:00:00

  • Tetra-triethyleneoxysulfonyl substituted zinc phthalocyanine for photodynamic cancer therapy.

    abstract：:Photodynamic therapy (PDT) has emerged as an effective and minimally invasive treatment option for several diseases, including some forms of cancer. However, several drawbacks of the approved photosensitizers (PS), such as insufficient light absorption at therapeutically relevant wavelengths hampered the clinical effe...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章,评审

    doi：10.1016/j.pdpdt.2015.07.001

    authors： Kuzyniak W,Ermilov EA,Atilla D,Gürek AG,Nitzsche B,Derkow K,Hoffmann B,Steinemann G,Ahsen V,Höpfner M

    更新日期：2016-03-01 00:00:00

  • Synthesis of axially disubstituted silicon phthalocyanines and investigation of photodynamic effects on HCT-116 colorectal cancer cell line.

    abstract：:Photodynamic therapy is one of the hot topics in cancer studies. Photosensitizing chemical substrates are stimulated by light having a specific wavelength to cause fatal effect on different kinds of targets. In this study, axially 4-{[(1E)-2-furylmethylene]amino}phenol, 4-{[(1E)-2-thienylmethylene]amino}phenol and 4-{...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2018.05.009

    authors： Sarı C,Eyüpoğlu FC,Değirmencioğlu İ,Bayrak R

    更新日期：2018-09-01 00:00:00

  • Efficacy of adjunctive photodynamic therapy on the clinical periodontal, HbA1c and advanced glycation end product levels among mild to moderate chronic periodontal disease patients with type 2 diabetes mellitus: A randomized controlled clinical trial.

    abstract：AIMS:To evaluate the clinical periodontal, serum glycated haemoglobin (HbA1c) and levels of advanced glycation end-products (AGEs) in the gingival crevicular fluid (GCF) among patients with periodontitis and type 2 diabetes mellitus (DM) after photodynamic therapy (PDT) as an adjunct to full-mouth disinfection (FMD). ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.pdpdt.2019.08.003

    authors： Mirza S,Khan AA,Al-Kheraif AA,Khan SZ,Shafqat SS

    更新日期：2019-12-01 00:00:00

  • Effect of Photofrin-mediated photocytotoxicity on a panel of human pancreatic cancer cells.

    abstract：BACKGROUND AND OBJECTIVE:Pancreatic cancer is a leading cause of cancer-related deaths in men and women. Early clinical studies suggest that photodynamic therapy (PDT) might be a useful modality in the management of this deadly disease. In this study, the photocytotoxicity of Photofrin-mediated PDT on different human p...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2012.11.001

    authors： Wang LW,Huang Z,Lin H,Li ZS,Hetzel F,Liu Md B

    更新日期：2013-09-01 00:00:00

  • Photoelimination of Streptococcus mutans with two methods of photodynamic and photothermal therapy.

    abstract：BACKGROUND:Increasing resistance of oral pathogens to conventional antibacterial agents has resulted to find alternative therapies to overcome resistance development problems; hence this in vitro study was carried out to investigate the efficacy of photoelimination of Streptococcus mutans with two methods of photodynam...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2013.07.002

    authors： Fekrazad R,Khoei F,Hakimiha N,Bahador A

    更新日期：2013-12-01 00:00:00

  • Porphyrins in urine after administration of 5-aminolevulinic acid as a potential tumor marker.

    abstract：BACKGROUND:Tumor markers are commonly used for cancer screening and as indicators of therapeutic effects. Certain types of tumor have been known to produce a variety of porphyrins after 5-aminolevulinic acid (ALA) administration. In this study, porphyrins in tumor-bearing mouse urine were analyzed after oral administra...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2011.04.004

    authors： Ishizuka M,Hagiya Y,Mizokami Y,Honda K,Tabata K,Kamachi T,Takahashi K,Abe F,Tanaka T,Nakajima M,Ogura S,Okura I

    更新日期：2011-12-01 00:00:00

  • In vitro evaluation of methylene blue removal from root canal after Photodynamic Therapy.

    abstract：:In Endodontics, photosensitizers' such as methylene blue and toluidine blue have been used in Photodynamic Therapy due to their positive results. However, they can stain the dentin from the root canal after Photodynamic Therapy (PDT). The present in vitro study aimed to evaluate different stain removal protocols from ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2017.10.024

    authors： Ramalho KM,Cunha SR,Mayer-Santos E,Eduardo CP,Freitas PM,Aranha ACC,Moura-Netto C

    更新日期：2017-12-01 00:00:00

  • Clinical efficacy of photodynamic therapy as an adjunct to mechanical debridement in the treatment of per-implantitis with abscess.

    abstract：AIM:The aim of the present clinical trial was to evaluate the efficacy of photodynamic therapy (PDT) as an adjunct to mechanical debridement (MD) in the treatment of severe peri-implantitis (PI) with abscess. MATERIALS AND METHODS:Selected individuals with severe PI were divided into two groups: Group A: received meth...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101750

    authors： Almohareb T,Alhamoudi N,Al Deeb M,Bin-Shuwaish MS,Mokeem SA,Saad Shafqat S,Vohra F,Abduljabbar T

    更新日期：2020-06-01 00:00:00

  • Photodynamic inactivation mediated by methylene blue or chlorin e6 against Streptococcus mutans biofilm.

    abstract：BACKGROUND:An appropriate photosensitizer (PS) for photodynamic inactivation should have a pronounced antimicrobial efficacy but low dark toxicity. The aim of this study is to investigate the concentration-dependent antimicrobial efficacies of methylene blue (MB) and chlorin e6 (Ce6), against Streptococcus mutans biofi...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101817

    authors： Nie M,Deng DM,Wu Y,de Oliveira KT,Bagnato VS,Crielaard W,Rastelli ANS

    更新日期：2020-09-01 00:00:00

  • Raman spectroscopy combined with multiple algorithms for analysis and rapid screening of chronic renal failure.

    abstract：:Chronic renal failure (CRF) is a symptom of kidney damage in the terminal stages. If a patient is not treated, then CRF will progress to uremia, which greatly reduces the lifespan of the patient. However, current screening strategies, including routine urine tests and medical imaging investigations, have poor sensitiv...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101792

    authors： Chen C,Yang L,Li H,Chen F,Chen C,Gao R,Lv XY,Tang J

    更新日期：2020-06-01 00:00:00

  • Validity and reliability of autofluorescence-based quantification method of dental plaque.

    abstract：BACKGROUND:The aim of this study was to evaluate validity and reliability of autofluorescence-based plaque quantification (APQ) method. METHODS:The facial surfaces of 600 sound anterior teeth of 50 subjects were examined. The subjects received dental plaque examination using Turesky modified Quigley Hein plaque index ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2015.10.003

    authors： Han SY,Kim BR,Ko HY,Kwon HK,Kim BI

    更新日期：2015-12-01 00:00:00

  • Comparison of 5-aminolevulinic acid photodynamic therapy and red light for treatment of photoaging.

    abstract：OBJECTIVE:The aim of this pilot study was to compare the efficacy of ALA-PDT and red light alone in the treatment of photoaging. METHODS:A total of 14 adults with photoaging skin were recruited. ALA-PDT or red light alone was applied to the forearm extensor. Before and after treatment, the treated sites were examined ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2014.02.007

    authors： Ji J,Zhang LL,Ding HL,Wang HW,Huang Z,Wang XX,Wang PR,Wang XL

    更新日期：2014-06-01 00:00:00

  • Could photodynamic therapy be utilized as a treatment modality for oral lichen planus?

    abstract：BACKGROUND:Oral lichen planus (OLP) is a chronic inflammatory disease. There is no standard treatment modality for OLP. Recently, photodynamic therapy (PDT) has been advocated as a new treatment modality for OLP. AIM:The aim of the present study is to compare the effect of PDT using methylene blue (MB) as a photosensi...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101677

    authors： Saleh W,Tageldin S,Khashaba E,Darwish M,Elnagdy S,Khashaba O

    更新日期：2020-06-01 00:00:00

  • The clinical trial on the safety and effectiveness of the photodynamic diagnosis of non-muscle-invasive bladder cancer using fluorescent light-guided cystoscopy after oral administration of 5-aminolevulinic acid (5-ALA).

    abstract：OBJECTIVE:To examine the utility and safety of photodynamic diagnosis (PDD) after oral administration of 5-aminolevulinic acid (5-ALA) (ALA-PDD) of non-muscle-invasive bladder cancer (NMIBC) using fluorescent-light (FL)-cystoscopy. METHODS:The study was a single-arm, open-label, multi-center prospective study on ALA-P...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 临床试验,杂志文章,多中心研究

    doi：10.1016/j.pdpdt.2015.12.011

    authors： Inoue K,Matsuyama H,Fujimoto K,Hirao Y,Watanabe H,Ozono S,Oyama M,Ueno M,Sugimura Y,Shiina H,Mimata H,Azuma H,Nagase Y,Matsubara A,Ito YM,Shuin T

    更新日期：2016-03-01 00:00:00

  • Antimicrobial activity of hypochlorite solutions and reciprocating instrumentation associated with photodynamic therapy on root canals infected with Enterococcus faecalis - An in vitro study.

    abstract：INTRODUCTION:The aim of this study is to evaluate the antimicrobial activity of hypochlorite solutions and reciprocating instrumentation associated with photodynamic therapy (PDT). METHODS:One hundred and thirty two root canals were enlarged up to #35 K-file and inoculated with E.faecalis for 14 days. The 132 samples ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2018.07.015

    authors： Souza MA,Tumelero Dias C,Zandoná J,Paim Hoffmann I,Sanches Menchik VH,Palhano HS,Bertol CD,Rossato-Grando LG,Cecchin D,de Figueiredo JAP

    更新日期：2018-09-01 00:00:00

  • Diagnostic accuracy of optical coherence tomography in actinic keratosis and basal cell carcinoma.

    abstract：BACKGROUND:Early diagnosis of non-melanoma skin cancer (NMSC) is potentially possible using optical coherence tomography (OCT) which provides non-invasive, real-time images of skin with micrometre resolution and an imaging depth of up to 2mm. OCT technology for skin imaging has undergone significant developments, impro...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2016.08.004

    authors： Olsen J,Themstrup L,De Carvalho N,Mogensen M,Pellacani G,Jemec GB

    更新日期：2016-12-01 00:00:00