当前位置： SCI文献检索 > BRITISH JOURNAL OF CANCER期刊下所有文献 > Anti-inflammation induced by counter-irritation or by treatment with non-steroidal agents inhibits the growth of a tumour of non-detected immunogenicity.

Anti-inflammation induced by counter-irritation or by treatment with non-steroidal agents inhibits the growth of a tumour of non-detected immunogenicity.

Abstract：

:Counter-irritation (CI) triggered by different non-specific irritant stimuli delayed the growth of a murine tumour of non-detected immunogenicity. The syngeneic LB tumour transplant by itself also induced CI and decreased the number of leukocytes migrating to a secondary s.c. irritant stimulus, e.g. sponge or carrageenan. On the other hand, partial inhibition of cell migration by treatment with either 0.5 mg kg-1 indomethacin or 0.3 mg kg-1 piroxicam retarded LB tumour growth, presumably by a mechanism unrelated to inhibition of immune responses by PGE2. It is suggested that CI may play a role in the early stages of concomitant resistance.

journal_name

Br J Cancer

journal_title

British journal of cancer

authors

Sordelli DO,Fontán PA,Meiss RP,Ruggiero RA,Bustuoabad OD

doi

10.1038/bjc.1989.349

subject

Has Abstract

pub_date

1989-11-01 00:00:00

pages

734-8

issue

5

eissn

0007-0920

issn

1532-1827

journal_volume

60

pub_type

杂志文章

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