Abstract:
:The betel quid is one of the most commonly consumed psychoactive substances in the world. By archaeological evidence like the occurrence of areca nuts in archaeological sites, the typical overall reddish-brown staining on prehistoric human teeth or specific artifacts linked with the habit, it is assumed that this tradition reaches back to prehistoric times. Since this kind of evidence is indirect, it is frequently doubted. The present study provides the earliest direct analytical indication of betel nut chewing in human history. A typical stained tooth from an Iron Age skeleton (site Gò Ô Chùa in Southern Vietnam, 400-100 BC) was analyzed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) and liquid chromatography-high-resolution mass spectrometry (LC-HR-ToF-MS) and the alkaloid arecoline which is specific for Areca catechu L. (Arecaceae) was detected.
journal_name
J Psychoactive Drugsjournal_title
Journal of psychoactive drugsauthors
Krais S,Klima M,Huppertz LM,Auwärter V,Altenburger MJ,Neukamm MAdoi
10.1080/02791072.2016.1264647subject
Has Abstractpub_date
2017-01-01 00:00:00pages
11-17issue
1eissn
0279-1072issn
2159-9777journal_volume
49pub_type
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