Abstract:
:Summarized are psychonautic bioassays (human self-experiments) of pharmañopo--crystalline bufotenine (5-HO-DMT; 5-hydroxy-N,N-dimethyltryptamine; dimethylserotonine), at times combined with harmaline or harmine-via intranasal, sublingual, intrarectal, pulmonary (inhaled vapor) and oral routes. This is done by way of pharmacological modeling of diverse South American shamanic inebriants, principally the snuffs ñopolyopo and cebílhaáj, prepared from seeds of Anadenanthera peregrina var. peregrina and A. colubrina var. Cebil, respectively. Psychoptic (visionary) activity of bufotenine has been established and the 1967 Holmstedt-Lindgren hypothesis of the paricá effect-intranasal potentiation of tryptamines by concomitant administration of monoamine-oxidase-inhibiting (MAOI) beta-carbolines from stems of Banisteriopsis caapi admixed with the snuffs-has been confirmed by 25 psychonautic bioassays. Salient phytochemical and psychonautic literature is reviewed, and isolation of bufotenine from Anadenanthera seeds detailed (with one table and eight references).
journal_name
J Psychoactive Drugsjournal_title
Journal of psychoactive drugsauthors
Ott Jdoi
10.1080/02791072.2001.10400574subject
Has Abstractpub_date
2001-07-01 00:00:00pages
273-81issue
3eissn
0279-1072issn
2159-9777journal_volume
33pub_type
杂志文章,评审abstract::Research studies that collect biological measures of drug use have traditionally utilized laboratory urinalysis. Several recent studies have also documented the utility of laboratory oral fluid (OF) analysis. A new method of drug testing-instant OF technology--may offer a quicker, equally accurate alternative to labor...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2006.10399845
更新日期:2006-06-01 00:00:00
abstract::The betel quid is one of the most commonly consumed psychoactive substances in the world. By archaeological evidence like the occurrence of areca nuts in archaeological sites, the typical overall reddish-brown staining on prehistoric human teeth or specific artifacts linked with the habit, it is assumed that this trad...
journal_title:Journal of psychoactive drugs
pub_type: 历史文章,杂志文章
doi:10.1080/02791072.2016.1264647
更新日期:2017-01-01 00:00:00
abstract::Eighty-one subjects who used ayahuasca at least once in North America answered a lengthy set of open-ended questions and completed the 81-item After the Spiritual Experience Questionnaire. An additional 50 ayahuasca users were interviewed in person. The data for this study represent ayahuasca experience based on more ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2012.703100
更新日期:2012-07-01 00:00:00
abstract::This study explored associations between adult Latina heavy drinking behaviors and potential psychosocial and demographic correlates. It used mother-daughter dyads and a cross-sectional design. Data were drawn from a community-based sample of 158 dyads of adult Latinas (n=316), age 18 years or older, recruited between...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2010.10400708
更新日期:2010-12-01 00:00:00
abstract::Inhalant use is a serious global problem with consequences equal to or surpassing those of other drugs. Regrettably, few prior studies have examined inhalant users' patterns of service and treatment utilization. The purpose of this study is to identify factors associated with service use and barriers to treatment amon...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2011.566504
更新日期:2011-01-01 00:00:00
abstract::Psychosocial treatments for methamphetamine dependence are of limited effectiveness. Thus, a significant need exists for add-on therapy for this substance user disorder. The aim of this study was to develop and test a novel text messaging intervention for use as an adjunct to cognitive behavioral group therapy for met...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,随机对照试验
doi:10.1080/02791072.2013.847995
更新日期:2013-11-01 00:00:00
abstract::The many pressing medical, psychological, legal, and ethical problems associated with substance abuse by pregnant and parenting women present daunting challenges. One approach is to adopt a legal perspective where the rights of mothers, fetuses, and children are pitted against one another in courtrooms and state legis...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.1997.10400174
更新日期:1997-01-01 00:00:00
abstract::In light of New York's recently reinforced strategy to end the AIDS epidemic by expanding testing, treatment, and access to pre-exposure prophylaxis (PrEP), we assessed drug use and sexual risk behaviors, along with HIV/Hepatitis C virus (HCV) transmission and prevention knowledge among non-treatment-seeking adults wi...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2016.1259518
更新日期:2017-01-01 00:00:00
abstract::As many as 10 million people will die annually by the year 2030 due to tobacco-related causes. While much research has focused on cigarettes, the increasing popularity of smoking hookah (water pipe) has received much less attention. Epidemiological studies have been carried out in India, Pakistan, Syria, Kuwait, and L...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2011.587707
更新日期:2011-04-01 00:00:00
abstract::5-Methoxy-N,N-Dimethyltryptamine (5-MeO-DMT) is a potent, fast-acting psychedelic. Anecdotal reports from 5-MeO-DMT users suggest that they employ a variety of benefit enhancement (BE) strategies aimed to increase positive effects and decrease any potential challenging effects of the substance, but no empirical study ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2020.1737763
更新日期:2020-07-01 00:00:00
abstract::In this article the authors explore the experience of craving of methamphetamine users and seek to illuminate how differences in craving contribute to use patterns. Using in-depth interviewing, data were collected from 82 active methamphetamine users in the metropolitan Atlanta area. The constant comparison method com...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2006.10400602
更新日期:2006-11-01 00:00:00
abstract::This study surveyed 422 individuals being treated in a substance abuse treatment program that offers various levels of care in order to learn about OxyContin use among this population. Focus areas included exposure and use of OxyContin, how this medication was obtained, reasons for initial use, and whether users of Ox...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2007.10400613
更新日期:2007-09-01 00:00:00
abstract::The patient-reported toxicity of an overdose of intravenous methamphetamine is described. The authors report the case of a 34-year old man who inadvertently injected himself with approximately 2.3 grams of methamphetamine. The patient reported disorientation, hallucinations, hyperthermia, photophobia, orthostasis and ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2001.10399926
更新日期:2001-10-01 00:00:00
abstract::The practice of injecting shared drugs, in which drug users prepare, divide and inject portions of a drug solution, is a means of transmitting HIV, HCV, and other blood-borne pathogens. This study examined the process of injecting shared drugs among drug users in San Juan, Puerto Rico, through detailed observations of...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2005.10399747
更新日期:2005-03-01 00:00:00
abstract::Substance use is common among young people and can escalate into significant problems for affected individuals and their families. Family responses can influence the course of youth substance use and its consequences for family members, including parents and siblings. Family-level interventions developed to date have ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2008.10400643
更新日期:2008-09-01 00:00:00
abstract::Ibogaine is an indole alkaloid derived from the root bark of the African shrub Tabernan the iboga and it has been used for many years as a medicinal and ceremonial agent in West Central Africa. Furthermore, both anecdotal observations and recent studies suggest that ibogaine alleviates withdrawal symptoms and reduces ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.2004.10399729
更新日期:2004-06-01 00:00:00
abstract::This article documents the prevalence of injection-related HIV risk behaviors among a sample of 758 Mexican-American, Puerto Rican, and African-American drug injectors derived from the National Institute on Drug Abuse Cooperative Agreement database. The results show that the two Hispanic subgroups had higher injection...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.1998.10399699
更新日期:1998-07-01 00:00:00
abstract::As a complement to research evaluating botanical marijuana as a medical therapy for various somatic and psychiatric conditions, there is a growing body of research assessing marijuana users' self-reports of the symptoms and conditions for which they use marijuana without a physician's recommendation. As part of two la...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2015.1096433
更新日期:2015-11-01 00:00:00
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journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.1990.10472542
更新日期:1990-04-01 00:00:00
abstract::A wide range of both prescription and nonprescription drugs has been reported to affect human sexual functioning. While the sexual side effects resulting from drug use have often been attributed to adrenergic, anticholinergic or dopaminergic activity, the present review considers the potential role of serotonin. Based...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.1992.10471616
更新日期:1992-01-01 00:00:00
abstract::Many recent studies have clearly documented the development of tolerance, dependence, and addiction to benzodiazepines. In spite of these studies and reviews of the literature, confusion remains regarding the risk and benefits of the use of benzodiazepines in medical practice. The source of the confusion arises in par...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.1990.10472194
更新日期:1990-01-01 00:00:00
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journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.1990.10472539
更新日期:1990-04-01 00:00:00
abstract::Drug testing at work is rapidly becoming the standard in the United States. For drug testing to fulfill its promise as a vital part of the effort to end the drug abuse epidemic, it is essential that the tests be reliable so that people who are not using drugs are not falsely accused and that legitimate medical use of ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.1990.10472219
更新日期:1990-10-01 00:00:00
abstract::The study aimed to examine the age of onset of stages of alcohol use in the general population, and to estimate the association of cohort use with the probability of transitioning from alcohol use to alcohol use disorder (AUD) and remission. French data (N = 2,894) from the European Study of the Epidemiology of Mental...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2019.1612536
更新日期:2019-11-01 00:00:00
abstract::Addiction is a primary, chronic disease involving brain reward, motivation, memory and related circuitry; it can lead to relapse, progressive development, and the potential for fatality if not treated. While pathological use of alcohol and, more recently, psychoactive substances have been accepted as addictive disease...
journal_title:Journal of psychoactive drugs
pub_type: 社论
doi:10.1080/02791072.2012.662105
更新日期:2012-01-01 00:00:00
abstract::Marijuana (MJ) refusal self-efficacy and obsessive/harmonious passion for MJ use are associated with use and related consequences but have not been examined simultaneously. We examined the relation among obsessive/harmonious passion for MJ use, refusal self-efficacy, frequency of use, and related consequences in an on...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2019.1596334
更新日期:2019-09-01 00:00:00
abstract::We investigated the association between tramadol use, co-morbid substance use disorders and hepatitis in former adolescent psychiatric inpatients. The study sample consisted of 508 adolescents, admitted to psychiatric inpatient care between 13 and 17 years of age. Follow-up information of tramadol prescriptions, subst...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2019.1671638
更新日期:2020-04-01 00:00:00
abstract::This study examines hypotheses and builds models to help clarify the causal connections between drugs and violence outcomes among Mexican-American male gang members. The study uses cross-sectional data of 160 male gang members sampled from 26 gangs in a Southwestern city. A life-history /intensive interview using clos...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2006.10399835
更新日期:2006-06-01 00:00:00
abstract::Individuals with substance use disorders (SUD) undergo treatment to recover from addiction. However, exerting self-control, which is essential for successful abstinence from drug addiction, can cause ego depletion. This study experimentally investigated the effect of ego depletion on interpersonal trust and examined p...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2020.1773585
更新日期:2020-11-01 00:00:00
abstract::Blood pressure and headache frequency were evaluated in normotensive male and female cocaine-dependent patients (N=43) participating in a placebo-controlled, double-blind trial of amlodipine for the treatment of cocaine dependence. Amlodipine produced a significant reduction in both systolic (p=0.04) and diastolic (p=...
journal_title:Journal of psychoactive drugs
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1080/02791072.2002.10399983
更新日期:2002-10-01 00:00:00