Abstract:
:Blood pressure and headache frequency were evaluated in normotensive male and female cocaine-dependent patients (N=43) participating in a placebo-controlled, double-blind trial of amlodipine for the treatment of cocaine dependence. Amlodipine produced a significant reduction in both systolic (p=0.04) and diastolic (p=0.01) blood pressures without producing dizziness or faintness. Placebo subjects had about three times the frequency of headaches compared to the amlodipine-treated subjects (p=0.004). The high frequency of headaches reported by cocaine-dependent individuals was significantly reduced by amlodipine and may reflect improved cerebrovascular tone.
journal_name
J Psychoactive Drugsjournal_title
Journal of psychoactive drugsauthors
Malcolm R,Liao J,Michel M,Cochran K,Pye W,Yeager D,Halushka PVdoi
10.1080/02791072.2002.10399983subject
Has Abstractpub_date
2002-10-01 00:00:00pages
415-9issue
4eissn
0279-1072issn
2159-9777journal_volume
34pub_type
临床试验,杂志文章,随机对照试验abstract::Pregabalin is approved for the management of neuropathic pain, partial-onset seizures, and fibromyalgia. Although it is considered to have low potential for abuse, reports of misuse of pregabalin are emerging. The present study contributes to this literature by presenting preliminary evidence of pregabalin misuse. Mix...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2020.1734695
更新日期:2020-04-01 00:00:00
abstract::Research has shown that a large number of individuals on probation have alcohol problems but only a fraction of them receive treatment. This study surveyed 145 probation officers about their views on alcohol problems among probationers. A previous analysis of the data found that two beliefs predicted probation officer...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2004.10399739
更新日期:2004-06-01 00:00:00
abstract::The Smoking Cessation Leadership Center (SCLC) was established in 2003 to increase the rate of smoking cessation attempts and the likelihood those efforts would succeed. Although smoking remains the number one cause of preventable death and disability, clinicians underperform in smoking cessation. Furthermore, many cl...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2017.1412546
更新日期:2018-01-01 00:00:00
abstract::Nicotine dependence in alcohol-involved adults is a long-ignored treatment problem. The absence of its discussion in the literature is difficult to defend in light of medical and epidemiological data on the cost and prevalence of this dual addiction. Most descriptive studies of alcohol abusers published in the past 20...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.1989.10472174
更新日期:1989-07-01 00:00:00
abstract::Research studies that collect biological measures of drug use have traditionally utilized laboratory urinalysis. Several recent studies have also documented the utility of laboratory oral fluid (OF) analysis. A new method of drug testing-instant OF technology--may offer a quicker, equally accurate alternative to labor...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2006.10399845
更新日期:2006-06-01 00:00:00
abstract::Crack cocaine use is linked to high rates of HIV and other sexually transmitted infections, as well as violence and criminal activity. Substance abuse treatment can play an important role in reducing drug use and related problems. However, many crack users do not want treatment, and those who do often encounter signif...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2003.10400498
更新日期:2003-10-01 00:00:00
abstract::Utilizing an expanded concept of level of burden, the impact of multiple problems experienced by women in a residential drug abuse treatment program on treatment retention and outcomes is investigated. Level of burden is defined in this study as the number and severity of problems, including psychological problems, co...
journal_title:Journal of psychoactive drugs
pub_type: 临床试验,杂志文章
doi:10.1080/02791072.1995.10471699
更新日期:1995-10-01 00:00:00
abstract::During the 1950s and 1960s, there was a tremendous surge in research into the effects of psychedelic drugs. When discussing this period of research, the discovery of the psychoactive properties of LSD in 1943 is often presented as the main, and sometimes only, driving force of the boom in research. This "Great Person,...
journal_title:Journal of psychoactive drugs
pub_type: 历史文章,杂志文章
doi:10.1080/02791072.2019.1581961
更新日期:2019-07-01 00:00:00
abstract::The aim of this study was to evaluate psychometric properties of the Drug Use Disorders Identification Test (DUDIT) and the Drug Abuse Screening Test (DAST-10) in prisoners with (n = 124) or without (n = 78) drug use disorder. Participants were evaluated with the DUDIT, the DAST-10, and the Addiction Profile Index-Sho...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2014.887162
更新日期:2014-04-01 00:00:00
abstract::The current study examined QEEG power and coherence of ayahuasca experiences with two experienced participants in a Brazilian jungle setting. An exploratory case series design was adopted for naturalistic field research. EEGs recorded during visual imagery was compared to eyes-closed baselines. The most important find...
journal_title:Journal of psychoactive drugs
pub_type: 临床试验,杂志文章
doi:10.1080/02791072.2005.10399798
更新日期:2005-06-01 00:00:00
abstract::A study of 200 street prostitutes documented a high prevalence of alcohol and drug abuse in their family of origin, during the drift into prostitution and as part of prostitution. Additionally, the study documented a high prevalence of substance abuse among the child molesters and rapists of the subjects. The existenc...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.1982.10471928
更新日期:1982-07-01 00:00:00
abstract::Brain-Derived Neurotrophic Factor (BDNF) is a neuropeptide that plays an important role in Central Nervous System development, plasticity, learning, and memory. Its role has been explored in alcohol-dependent patients, though the results have been inconclusive. Thus, we aimed to compare serum BDNF levels in alcohol-de...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2020.1795327
更新日期:2020-11-01 00:00:00
abstract::The study aimed to examine the age of onset of stages of alcohol use in the general population, and to estimate the association of cohort use with the probability of transitioning from alcohol use to alcohol use disorder (AUD) and remission. French data (N = 2,894) from the European Study of the Epidemiology of Mental...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2019.1612536
更新日期:2019-11-01 00:00:00
abstract::Similar to other sociological studies of Ecstasy use, the authors' research suggests that Ecstasy users tend to report positive effects of the drug. However, we also observed that most users experienced at least one adverse psychological outcome while using Ecstasy. The present study examines those negative experience...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.2002.10399954
更新日期:2002-04-01 00:00:00
abstract::The authors have been able to follow up on a number of residents over the years. Most of them have frequently referred to the helpfulness of the seminars during their reentry phase. Some have sought out private counseling once they felt problems cropping up. While there is no abundance of jobs awaiting the adolescent ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.1984.10524472
更新日期:1984-01-01 00:00:00
abstract::Savoring has covaried inversely with cannabis problems and moderated the association between cannabis use and negative consequences related to use. Research has not yet addressed the acceptability of savoring interventions for cannabis users. The present study aimed to replicate the finding of savoring as a protective...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2020.1853284
更新日期:2020-11-22 00:00:00
abstract::Ibogaine is an indole alkaloid derived from the root bark of the African shrub Tabernan the iboga and it has been used for many years as a medicinal and ceremonial agent in West Central Africa. Furthermore, both anecdotal observations and recent studies suggest that ibogaine alleviates withdrawal symptoms and reduces ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.2004.10399729
更新日期:2004-06-01 00:00:00
abstract::Persons presenting with concurrent psychiatric and substance problems present unique challenges for diagnosis and for effective and rational treatment planning. This is especially true for psychiatrists attempting to prescribe pharmacologic interventions which will promote recovery from both disorders and improve func...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.1999.10471727
更新日期:1999-01-01 00:00:00
abstract::A significant number of individuals with co-occurring substance abuse and mental health disorders do not engage, stay, and/or complete residential treatment. The purpose of this study is to identify factors during the initial phase of treatment which predict retention in private residential treatment for individuals w...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,多中心研究
doi:10.1080/02791072.2013.785817
更新日期:2013-04-01 00:00:00
abstract::Changing paradigms of health care and increasing knowledge of opioid addiction continue to influence the attitudes of the health profession toward methadone maintenance treatment (MMT). This approach has again reached the forefront of attention because of its significant role in reducing HIV transmission associated wi...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.1996.10472486
更新日期:1996-07-01 00:00:00
abstract::College students across the U.S. engage in nonmedical use of prescription stimulants (NMUPS) at increasing rates. While it has been found that use is frequently motivated by a belief that stimulants will act as a study aid, little is known about predictors of NMUPS. The present study addressed impulsivity, outcome exp...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2012.662083
更新日期:2012-01-01 00:00:00
abstract::Cannabis is generally used to enhance mood (quality of life), but it is not known whether it has this effect in the medium to longer term. Little is currently known about the temporal sequence between cannabis use and the quality of life (QOL). Data are taken from a prospective longitudinal study of pregnant women rec...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2015.1014121
更新日期:2015-04-01 00:00:00
abstract::To better understand methamphetamine (MA) use patterns and the process of recovery, qualitative interviews were conducted with adult MA users (n = 20), comparing a sample that received substance abuse treatment with those who had not received treatment. Respondents provided detailed information on why and how they cha...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2014.914611
更新日期:2014-07-01 00:00:00
abstract::A number of factors that coalesced in the Venus figurines of the Late Neolithic culture from Hungary have been identified with dominant hallucinatory themes, suggesting the crucial role of ecstatic religion in this culture. This article provides a review of the nature and role of hallucinogens in the ecstatic religion...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.1989.10472147
更新日期:1989-01-01 00:00:00
abstract::Using signs, symptoms and serum methadone levels to guide evaluation, the authors treated 164 patients in a methadone maintenance program with doses of methadone exceeding 100 mg/d. The mean dose of these higher dose (HD) patients was 211 mg/d (range 110-780 mg/d). A comparison group (C) of 101 patients was randomly s...
journal_title:Journal of psychoactive drugs
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1080/02791072.1999.10471730
更新日期:1999-04-01 00:00:00
abstract::Scientific literature increasingly calls for studies to translate evidence-based interventions into real-world contexts balancing fidelity to the original design and fit to the new setting. The Risk Avoidance Partnership (RAP) is a health promotion intervention originally designed to train active drug users to become ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2015.1050535
更新日期:2015-07-01 00:00:00
abstract::This research explores the relationship between use of certain drugs and aggressive crimes among Mexican-American and White male arrestees in San Antonio, Texas, for 1992. This is based on a Drug Use Forecasting (DUF) sample of 534 male arrestees administered a drug urine analysis test and questionnaire by the Departm...
journal_title:Journal of psychoactive drugs
pub_type: 临床试验,杂志文章
doi:10.1080/02791072.1995.10471682
更新日期:1995-04-01 00:00:00
abstract::A review of the literature suggests that a common psychobiological process is associated with various altered states of consciousness (ASC) utilized by shamans, meditators, and mediums. However, the shamanic state of consciousness (SSC) can be differentiated physiologically from possession trance states. The psychophy...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.1989.10472140
更新日期:1989-01-01 00:00:00
abstract::Using archival data from Bay Area Addiction Research and Treatment (BAART), a methadone treatment provider, this study examined the efficacy of the clinical intervention of counseling on cocaine use by BAART patients. California State Assembly Bill 2071 mandated that patients at methadone clinics be required to underg...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,meta分析
doi:10.1080/02791072.2003.10400009
更新日期:2003-04-01 00:00:00
abstract::Methoxphenidine (MXP) was one of several NMDA antagonists marketed in 2013 to replace the recently controlled compound Methoxetamine (MXE). A steep rise in user interest was recorded, despite vendor cautioning of limited user feedback. The study presented a phenomenological analysis of MXP experiences amongst recreati...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2014.974002
更新日期:2015-01-01 00:00:00