Abstract:
:A wide range of both prescription and nonprescription drugs has been reported to affect human sexual functioning. While the sexual side effects resulting from drug use have often been attributed to adrenergic, anticholinergic or dopaminergic activity, the present review considers the potential role of serotonin. Based on animal studies, serotonin has been shown to either facilitate or inhibit sexual activity depending on which serotonin receptor subtype is activated. However, few studies have been done in the human that assess the effects of drugs that bind selectively to serotonin receptors. Consequently, little is known about the role of serotonin in human sexual functioning. In this review, a wide range of drugs that affect both brain serotonergic systems and human sexual behavior is examined in an effort to determine the possible role of serotonin in human sexual behavior. A review of the literature is consistent with the hypothesis that the 5-HT1A and the 5-HT2 receptor subtypes play a facilitatory role in human sexual behavior. The evidence suggests that drugs that act as agonists on these receptor sites enhance sexual functioning in the human, while those that act as antagonists inhibit sexual functioning.
journal_name
J Psychoactive Drugsjournal_title
Journal of psychoactive drugsauthors
Meston CM,Gorzalka BBdoi
10.1080/02791072.1992.10471616subject
Has Abstractpub_date
1992-01-01 00:00:00pages
1-40issue
1eissn
0279-1072issn
2159-9777journal_volume
24pub_type
杂志文章,评审abstract::Methamphetamine, called meth, crystal, or speed, is a central nervous system stimulant that can be injected, smoked, snorted, or ingested orally; prolonged use at high levels results in dependence. Methamphetamine (MA) is a derivative of amphetamine, which was widely prescribed in the 1950s and 1960s as a medication f...
journal_title:Journal of psychoactive drugs
pub_type: 历史文章,杂志文章
doi:10.1080/02791072.2000.10400221
更新日期:2000-04-01 00:00:00
abstract::Holotropic states (a large special subgroup of nonordinary states of consciousness) have been the focus of many fields of modern research, such as experiential psychotherapy, clinical and laboratory work with psychedelic substances, field anthropology, thanatology, and therapy with individuals undergoing psychospiritu...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.1998.10399710
更新日期:1998-10-01 00:00:00
abstract::Methoxphenidine (MXP) was one of several NMDA antagonists marketed in 2013 to replace the recently controlled compound Methoxetamine (MXE). A steep rise in user interest was recorded, despite vendor cautioning of limited user feedback. The study presented a phenomenological analysis of MXP experiences amongst recreati...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2014.974002
更新日期:2015-01-01 00:00:00
abstract::Psychosocial treatments for methamphetamine dependence are of limited effectiveness. Thus, a significant need exists for add-on therapy for this substance user disorder. The aim of this study was to develop and test a novel text messaging intervention for use as an adjunct to cognitive behavioral group therapy for met...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,随机对照试验
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更新日期:2013-11-01 00:00:00
abstract::Using archival data from Bay Area Addiction Research and Treatment (BAART), a methadone treatment provider, this study examined the efficacy of the clinical intervention of counseling on cocaine use by BAART patients. California State Assembly Bill 2071 mandated that patients at methadone clinics be required to underg...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,meta分析
doi:10.1080/02791072.2003.10400009
更新日期:2003-04-01 00:00:00
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journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2015.1130884
更新日期:2016-04-01 00:00:00
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journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.2006.10399822
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abstract::Despite a long history of extravagant claims followed by sobering discomfirmations, advocates of controlled drinking continue to promote nonabstinent treatment goals and procedures for alcoholics. Recent claims by Stanton Peele in favor of controlled drinking are examined critically in the context of a continuing deba...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.1990.10472550
更新日期:1990-07-01 00:00:00
abstract::This study arose out of a prominent clinical need: effective treatment for comorbid posttraumatic stress disorder (PTSD) and substance use disorder (SUD) in civilian men. This dual diagnosis is estimated to occur in up to 38% of men in substance abuse treatment, and generally portends a more severe clinical course tha...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2005.10399816
更新日期:2005-12-01 00:00:00
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journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2019.1612536
更新日期:2019-11-01 00:00:00
abstract::This qualitative study, presented in two parts, refines the model of how chemically dependent adolescents initiate and engage in the recovery process. Part 1 describes the research process and results used to derive the model. The model was derived from theory grounded in verbatim reports of 30 chemically dependent pa...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2004.10400033
更新日期:2004-09-01 00:00:00
abstract::To examine the effectiveness of two visual representation counseling techniques for reducing illicit drug use, participants were randomly assigned to receive standard treatment "as usual" or standard treatment supplemented with free mapping or free plus guide mapping. Each counselor delivered all types of treatment to...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,随机对照试验
doi:10.1080/02791072.2009.10399911
更新日期:2009-06-01 00:00:00
abstract::Violence has become a critical public health issue in the United States. It has had a particularly devastating impact on the health and well being of Native American women and children. The relationship between aggression and substance use is an intrinsic one: Native women often bear the brunt of violence in drinking ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2005.10400520
更新日期:2005-09-01 00:00:00
abstract::Until recently, few programs were available for children whose mothers are in recovery. A refinement of the gender-specific model of substance abuse treatment, the "family-focused" approach, has placed increased emphasis on the needs of children and other family members. However, because these programs are relatively ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2003.10400015
更新日期:2003-07-01 00:00:00
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journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2006.10399832
更新日期:2006-03-01 00:00:00
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journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.1990.10472542
更新日期:1990-04-01 00:00:00
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journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.1994.10472263
更新日期:1994-04-01 00:00:00
abstract::Drug testing at work is rapidly becoming the standard in the United States. For drug testing to fulfill its promise as a vital part of the effort to end the drug abuse epidemic, it is essential that the tests be reliable so that people who are not using drugs are not falsely accused and that legitimate medical use of ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
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更新日期:1990-10-01 00:00:00
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journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
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更新日期:1988-04-01 00:00:00
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journal_title:Journal of psychoactive drugs
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更新日期:2019-04-01 00:00:00
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journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
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journal_title:Journal of psychoactive drugs
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doi:10.1080/02791072.2003.10400025
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journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
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更新日期:2015-07-01 00:00:00
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journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2007.10399874
更新日期:2007-06-01 00:00:00
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journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.1997.10400174
更新日期:1997-01-01 00:00:00
abstract::This research explores the relationship between use of certain drugs and aggressive crimes among Mexican-American and White male arrestees in San Antonio, Texas, for 1992. This is based on a Drug Use Forecasting (DUF) sample of 534 male arrestees administered a drug urine analysis test and questionnaire by the Departm...
journal_title:Journal of psychoactive drugs
pub_type: 临床试验,杂志文章
doi:10.1080/02791072.1995.10471682
更新日期:1995-04-01 00:00:00
abstract::Albert Hoffman suggested that low doses of LSD might be an appropriate alternative to Ritalin. Following this possibility, a systematic exploration of the effects of "microdoses," comprising hundreds of lengthy descriptive reports, was undertaken. Based on these reports, using a psychedelic in the microdose range (10 ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,多中心研究
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更新日期:2019-04-01 00:00:00
abstract::Cannabis is generally used to enhance mood (quality of life), but it is not known whether it has this effect in the medium to longer term. Little is currently known about the temporal sequence between cannabis use and the quality of life (QOL). Data are taken from a prospective longitudinal study of pregnant women rec...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
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更新日期:2015-04-01 00:00:00
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journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.2012.684624
更新日期:2012-04-01 00:00:00
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journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
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更新日期:2020-11-01 00:00:00