Abstract:
:Albert Hoffman suggested that low doses of LSD might be an appropriate alternative to Ritalin. Following this possibility, a systematic exploration of the effects of "microdoses," comprising hundreds of lengthy descriptive reports, was undertaken. Based on these reports, using a psychedelic in the microdose range (10 micrograms) every three days was determined to be safe across a wide variety of individuals and conditions. Over 18 months, more than a thousand individuals from 59 countries did a daily evaluation of negative and positive emotional state using the PANAS checklist plus written reports for between one week and four months. Participant reports suggested that spaced but repeated microdoses were followed by improvements in negative moods, especially depression, and increases in positive moods. Increased energy, improved work effectiveness, and improved health habits were observed in clinical and non-clinical populations. Smaller samples described alleviation of symptoms in migraine headaches, pre-menstrual syndromes, traumatic brain injury, shingles, and other conditions not previously associated with psychedelic use.
journal_name
J Psychoactive Drugsjournal_title
Journal of psychoactive drugsauthors
Fadiman J,Korb Sdoi
10.1080/02791072.2019.1593561subject
Has Abstractpub_date
2019-04-01 00:00:00pages
118-122issue
2eissn
0279-1072issn
2159-9777journal_volume
51pub_type
杂志文章,多中心研究abstract::We investigated the association between tramadol use, co-morbid substance use disorders and hepatitis in former adolescent psychiatric inpatients. The study sample consisted of 508 adolescents, admitted to psychiatric inpatient care between 13 and 17 years of age. Follow-up information of tramadol prescriptions, subst...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2019.1671638
更新日期:2020-04-01 00:00:00
abstract::Changing paradigms of health care and increasing knowledge of opioid addiction continue to influence the attitudes of the health profession toward methadone maintenance treatment (MMT). This approach has again reached the forefront of attention because of its significant role in reducing HIV transmission associated wi...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.1996.10472486
更新日期:1996-07-01 00:00:00
abstract::"Drug-free" outpatient programs deliver treatment to the largest number of patients of all treatment modalities in the U.S., providing a significant opportunity to expand access to medication treatments for substance use disorders. This analysis examined staff perceptions of organizational dynamics associated with the...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2015.1130884
更新日期:2016-04-01 00:00:00
abstract::Substance use is common among young people and can escalate into significant problems for affected individuals and their families. Family responses can influence the course of youth substance use and its consequences for family members, including parents and siblings. Family-level interventions developed to date have ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2008.10400643
更新日期:2008-09-01 00:00:00
abstract::Methadone maintenance has been used for decades to treat opioid-dependent pregnant women. The outcomes of pregnancies thus treated are vastly improved over the outcomes of pregnancies complicated by street drug use. Despite its long history of successful use during pregnancy, little is known about the long-term effect...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.1994.10472263
更新日期:1994-04-01 00:00:00
abstract::This research explores the relationship between use of certain drugs and aggressive crimes among Mexican-American and White male arrestees in San Antonio, Texas, for 1992. This is based on a Drug Use Forecasting (DUF) sample of 534 male arrestees administered a drug urine analysis test and questionnaire by the Departm...
journal_title:Journal of psychoactive drugs
pub_type: 临床试验,杂志文章
doi:10.1080/02791072.1995.10471682
更新日期:1995-04-01 00:00:00
abstract::Assessing the health status of ayahuasca users has been challenging due to the limitations involved in randomized clinical trials and psychometric approaches. The main objective of this study is the implementation of an approach based on public health indicators. We developed a self-administered questionnaire that was...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2019.1567961
更新日期:2019-04-01 00:00:00
abstract::Inhalant use is a serious global problem with consequences equal to or surpassing those of other drugs. Regrettably, few prior studies have examined inhalant users' patterns of service and treatment utilization. The purpose of this study is to identify factors associated with service use and barriers to treatment amon...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2011.566504
更新日期:2011-01-01 00:00:00
abstract::The initiation of the first methadone maintenance treatment program (MMT) in Macao was founded in collaboration between MMT clinics in the USA and Israel. All patients admitted into treatment between October 2005 and October 2008 were prospectively followed through March 2010. Of the 163 patients, 81% were male, the m...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2013.825032
更新日期:2013-09-01 00:00:00
abstract::Traditionally, researchers and clinicians have viewed street heroin users as representing an end point in a drug-using career. It is toward this population that major national treatment efforts have been directed. Concomitant with the historical national concern about heroin use has been concern about the increase in ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.1992.10471665
更新日期:1992-10-01 00:00:00
abstract::To better understand methamphetamine (MA) use patterns and the process of recovery, qualitative interviews were conducted with adult MA users (n = 20), comparing a sample that received substance abuse treatment with those who had not received treatment. Respondents provided detailed information on why and how they cha...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2014.914611
更新日期:2014-07-01 00:00:00
abstract::Existent profiles of Medical Marijuana Program (MMP) participants indicate common and co-morbid chronic diseases, yet evidence on disability or functioning as well as comparisons with general populations are largely lacking. This study compared health, substance use, and functioning status among formally approved MMP ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2016.1264648
更新日期:2017-01-01 00:00:00
abstract::Until recently, few programs were available for children whose mothers are in recovery. A refinement of the gender-specific model of substance abuse treatment, the "family-focused" approach, has placed increased emphasis on the needs of children and other family members. However, because these programs are relatively ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2003.10400015
更新日期:2003-07-01 00:00:00
abstract::There is a growing body of evidence to support the use of medical cannabis as an adjunct to or substitute for prescription opiates in the treatment of chronic pain. When used in conjunction with opiates, cannabinoids lead to a greater cumulative relief of pain, resulting in a reduction in the use of opiates (and assoc...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.2012.684624
更新日期:2012-04-01 00:00:00
abstract::Using signs, symptoms and serum methadone levels to guide evaluation, the authors treated 164 patients in a methadone maintenance program with doses of methadone exceeding 100 mg/d. The mean dose of these higher dose (HD) patients was 211 mg/d (range 110-780 mg/d). A comparison group (C) of 101 patients was randomly s...
journal_title:Journal of psychoactive drugs
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1080/02791072.1999.10471730
更新日期:1999-04-01 00:00:00
abstract::Savoring has covaried inversely with cannabis problems and moderated the association between cannabis use and negative consequences related to use. Research has not yet addressed the acceptability of savoring interventions for cannabis users. The present study aimed to replicate the finding of savoring as a protective...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2020.1853284
更新日期:2020-11-22 00:00:00
abstract::The Smoking Cessation Leadership Center (SCLC) was established in 2003 to increase the rate of smoking cessation attempts and the likelihood those efforts would succeed. Although smoking remains the number one cause of preventable death and disability, clinicians underperform in smoking cessation. Furthermore, many cl...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2017.1412546
更新日期:2018-01-01 00:00:00
abstract::Methamphetamine, called meth, crystal, or speed, is a central nervous system stimulant that can be injected, smoked, snorted, or ingested orally; prolonged use at high levels results in dependence. Methamphetamine (MA) is a derivative of amphetamine, which was widely prescribed in the 1950s and 1960s as a medication f...
journal_title:Journal of psychoactive drugs
pub_type: 历史文章,杂志文章
doi:10.1080/02791072.2000.10400221
更新日期:2000-04-01 00:00:00
abstract::Communities that are struggling to provide effective treatment for the challenging population of severely mentally ill clients who use alcohol and drugs have a growing research base on which to make policy decisions. Integrating outpatient treatment for mental health and addictive disorders appears to be more effectiv...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.2000.10400240
更新日期:2000-10-01 00:00:00
abstract::The practice of "dabbing" has seen an apparent upswing in popularity in recent months within American drug subcultures. "Dabbing" refers to the use of butane-extracted marijuana products that offer users much higher tetrahydrocannabinol content than flower cannabis through a single dosage process. Though considerably ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2015.1118173
更新日期:2016-01-01 00:00:00
abstract::Misuse of prescription opioids, particularly by adolescents, is a growing problem in the United States. It is a leading cause of death and disability in this age group. The primary form of treatment available to adolescents is drug free psychosocial programs. For the high risk group that has relapsed after traditional...
journal_title:Journal of psychoactive drugs
pub_type: 社论
doi:10.1080/02791072.2011.605643
更新日期:2011-07-01 00:00:00
abstract::Methoxphenidine (MXP) was one of several NMDA antagonists marketed in 2013 to replace the recently controlled compound Methoxetamine (MXE). A steep rise in user interest was recorded, despite vendor cautioning of limited user feedback. The study presented a phenomenological analysis of MXP experiences amongst recreati...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2014.974002
更新日期:2015-01-01 00:00:00
abstract::The patient-reported toxicity of an overdose of intravenous methamphetamine is described. The authors report the case of a 34-year old man who inadvertently injected himself with approximately 2.3 grams of methamphetamine. The patient reported disorientation, hallucinations, hyperthermia, photophobia, orthostasis and ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.2001.10399926
更新日期:2001-10-01 00:00:00
abstract::Nicotine dependence in alcohol-involved adults is a long-ignored treatment problem. The absence of its discussion in the literature is difficult to defend in light of medical and epidemiological data on the cost and prevalence of this dual addiction. Most descriptive studies of alcohol abusers published in the past 20...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.1989.10472174
更新日期:1989-07-01 00:00:00
abstract::Research on the relationship between psychoactive substance dependence and personality disorder has been difficult to interpret. Among the reasons for this difficulty are (1) shifts in conceptualizations of these two classes of disorders, (2) markedly different findings related to age, sex, other demographic variables...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.1989.10472153
更新日期:1989-04-01 00:00:00
abstract::Data from the Partnership Attitude Tracking Study are analyzed to provide a greater understanding of the contributing factors to alcohol and other drug use among children and adolescents. The data were collected from children (ages 9 to 12) and teenagers (ages 13 to 17) in central locations (usually shopping malls) lo...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.1993.10472273
更新日期:1993-07-01 00:00:00
abstract::Ibogaine is an indole alkaloid derived from the root bark of the African shrub Tabernan the iboga and it has been used for many years as a medicinal and ceremonial agent in West Central Africa. Furthermore, both anecdotal observations and recent studies suggest that ibogaine alleviates withdrawal symptoms and reduces ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章,评审
doi:10.1080/02791072.2004.10399729
更新日期:2004-06-01 00:00:00
abstract::Psychedelic plants and fungi have been used in indigenous medicinal traditions for millennia. Modern psychedelic research began when Albert Hofmann first synthesized lysergic acid diethylamide (LSD-25) in 1938. Five years later, became the first person to ingest LSD. Hofmann was unaware of the significance of his acti...
journal_title:Journal of psychoactive drugs
pub_type: 历史文章,杂志文章
doi:10.1080/02791072.2019.1606472
更新日期:2019-04-01 00:00:00
abstract::Three cases of delirium experienced by three young friends after recreational use of "ecstasy" are reported--a syndrome which, to the best of the authors' knowledge, has not been previously observed in MDMA abusers. Special attention is given to the etiological factors and clinical features of the adverse reaction. ...
journal_title:Journal of psychoactive drugs
pub_type: 杂志文章
doi:10.1080/02791072.1999.10471740
更新日期:1999-04-01 00:00:00
abstract::This research explored whether hypnotic suggestion could produce a subjective mindbody condition similar to that produced by the psychoactive drug methylenedioxy methamphetamine (MDMA, Ecstasy). Twelve participants received posthypnotic instructions to re-experience an MDMA-like state posthypnotically, similar to one ...
journal_title:Journal of psychoactive drugs
pub_type: 临床试验,杂志文章
doi:10.1080/02791072.2006.10399853
更新日期:2006-09-01 00:00:00