Abstract：
:The risks of transfusion-associated infectious disease have made increased efforts to avoid homologous transfusion imperative. Little attention has been focused on efforts to accelerate erythropoiesis as a method of reducing homologous blood use. Recombinant human erythropoietin (rHuEPO) has been shown to enhance erythropoiesis. The purpose of this study was to evaluate the effects of perioperative rHuEPO administration on postoperative erythropoiesis. Fifteen baboons were divided into three groups of five each. Group I received no rHuEPO. Group II received five daily preoperative doses of rHuEPO (1000 U/kg). Group III received five daily preoperative doses and 14 daily postoperative doses of rHuEPO (1000 U/kg). All animals underwent a laparotomy followed by an exchange transfusion to a final hematocrit of 15%. The time in days required to recover to hematocrits of 20% was significantly shorter in both groups that received preoperative doses of rHuEPO when compared with that of controls (3.3 vs 5.7 days, p less than 0.01). The recovery times to hematocrits of 25%, 30%, and baseline levels were all significantly shorter in the group that received both preoperative and postoperative doses of rHuEPO. The data show that perioperative dosage of rHuEPO significantly accelerates postoperative erythropoiesis. Perioperative administration of rHuEPO may reduce the requirements for homologous transfusion.
journal_name
Surgeryjournal_title
Surgeryauthors
Levine EA,Gould SA,Rosen AL,Sehgal LR,Egrie JC,Sehgal HL,Levine HD,Moss GSsubject
Has Abstractpub_date
1989-08-01 00:00:00pages
432-7; discussion 437-8issue
2eissn
0039-6060issn
1532-7361pii
0039-6060(89)90238-9journal_volume
106pub_type
杂志文章相关文献
SURGERY文献大全abstract：BACKGROUND:The purpose of this study was to elucidate the mechanism of reduced intestinal transit rate in the ileum as compared with the jejunum. METHODS:Twenty-one dogs were each instrumented with 12 strain gauge transducers, 2 collection cannulas, and an infusion catheter defining a 100 cm study in the midjejunum (n...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/s0039-6060(97)90288-9
更新日期：1997-02-01 00:00:00
abstract：:The effect of surgical trauma on the regulation of lipolysis was studied in isolated fat cells obtained before and 24 hours after elective cholecystectomy in 12 patients who were not obese and who were healthy otherwise. Surgery was accompanied by a twofold increase of the basal rate of lipolysis and by a significant ...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：:A 5 MHz continuous-wave Doppler probe was used intraoperatively to evaluate 25 in situ saphenous vein bypass grafts. At least one arteriovenous fistula per case and five retained competent posterior valvular leaflets were identified before completion angiography. The Doppler was able to distinguish a retained valve fr...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1984-11-01 00:00:00
abstract：BACKGROUND:Malignancy is a relative contraindication in transplant candidates, given the increased neoplastic risk accompanying posttransplant immunosuppression. However, the number of patients receiving a lung transplant despite pretransplant malignancy is rising, and their outcomes remain unclear. Our purpose was to ...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2019.01.008
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Complex anal fistulas are unsuitable for fistulotomy because of the risk of fecal incontinence. The anal fistula plug (AFP) has demonstrated fistula healing without sphincter division. This study aims to evaluate the cost-effectiveness of the AFP compared to the endoanal advancement flap (EAAF) as an alterna...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2009.05.018
更新日期：2010-01-01 00:00:00
abstract：INTRODUCTION:Routine, whole-body computed tomography imaging (PAN-SCAN) has been shown to identify unexpected injuries and alter the management of patients presenting with blunt trauma. We sought to characterize the changes in practice over time and the utility of PAN-SCAN imaging in elderly patients who fall and requi...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2013.07.015
更新日期：2013-10-01 00:00:00
abstract：BACKGROUND:A breast cancer (BC) history was elicited more frequently than expected among thyroid operation patients, which prompted an investigation of risks for concurrent or subsequent nonendocrine malignancies. METHODS:Of 94,939 patients at a tertiary referral center with breast, thyroid, or parathyroid disease fro...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2007.07.024
更新日期：2007-12-01 00:00:00
abstract：BACKGROUND:The efficacy of octreotide in the regulation of endocrine tumor secretion and symptomatology has been well documented. Its effects on neuroendocrine tumor generation and cell proliferation are less well understood. The purpose of this study was to determine if blockade of somatostatin receptors by octreotide...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1992-12-01 00:00:00
abstract：:The viability of the heart from irreversibly shocked dogs was evaluated. Thirty-one mongrel dogs were used to develop a uniformly lethal hemorrhagic shock model. The final model utilized a 30 mm. Hg mean arterial pressure with a 40 percent decompensation (uptake of reservoir blood). All control dogs subjected to this ...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1975-01-01 00:00:00
abstract：BACKGROUND:Routine and radical lymph node dissection is a clinical concern for improving the surgical outcome in patients with intrahepatic cholangiocarcinoma (ICC). The therapeutic value of the procedure during hepatectomy has, however, not been evaluated. METHODS:Between January 1990 and December 2004, 104 patients ...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2008.11.010
更新日期：2009-04-01 00:00:00
abstract：:We studied 28 patients who had undergone 30 operations for pheochromocytoma since 1964. The tumor types included bilateral, extra-adrenal, malignant, recurrent, and multiple endocrine neoplasia, with 20 tumors confined to the adrenal gland. The preoperative studies used to localize the tumor included ultrasonography, ...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1985-11-01 00:00:00
abstract：:Two granular cell tumors of the biliary tree are described, one in a 37-year-old black woman with obstructive jaundice and the other in a 26-year-old white woman with abdominal pain. These are rare soft tissue tumors that have an excellent prognosis when surgically excised. Almost all reported cases have been in young...
journal_title：Surgery
pub_type： 杂志文章,评审
doi：
更新日期：1988-03-01 00:00:00
abstract：:To determine if pretreatment of polytetrafluoroethylene (PTFE) vascular grafts with fibronectin (FN) increased platelet adherence to them and adversely affected their patency, we labeled autologous canine platelets with indium III-oxine and interposed a FN-coated, experimental, 4 mm inner diameter, 10 cm long PTFE pro...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1987-04-01 00:00:00
abstract：BACKGROUND:A minimally invasive step-up approach to necrotizing biliary pancreatitis often requires multiple interventions, delaying cholecystectomy. The risk of gallstone-related complications during this time interval is unknown, as is the feasibility and safety of cholecystectomy after minimally invasive step-up tre...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2020.11.002
更新日期：2020-12-12 00:00:00
abstract：:The object of this article is to assess the value of human serum albumin (HSA) in the initial resuscitation of hypotensive trauma victims. Thirty-six patients (mean age = 30 years) in shock from trauma who underwent laparotomies were randomly assigned to either Ringer's lactate solution (RL) resuscitation or 4% HSA in...
journal_title：Surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1981-04-01 00:00:00
abstract：:Treatment of rat allograft recipients before grafting with donor spleen cells and whole, pooled antidonor alloimmune serum results in indefinite renal allograft survival. The enhancement is immunologically specific. In these experiments a monoclonal, homogenous anti-BN antibody was produced by a hybridoma clone create...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1979-07-01 00:00:00
abstract：:A parapubic hernia, distinct from other lower abdominal wall hernias, is identified as a particular type of incisional hernia. This hernia results from the disruption of the musculotendinous elements of the abdominal wall as they insert into the pubis. This disruption is brought about by either the destruction of thes...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：BACKGROUND:Controversy exists about the routes of invasion (extrathyroidal versus lymphogenic extension) when differentiated carcinoma (DTC) and medullary thyroid carcinoma (MTC) invade the cervicovisceral axis (ie, larynx, trachea, esophagus). METHODS:We carried out an institutional analysis, from November 1994 to Oc...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1067/msy.2001.108699
更新日期：2001-01-01 00:00:00
abstract：:Planned excisions of tumors involving the abdominal or chest wall should not be compromised because of lack of tissue for wound closure. Reconstruction with an inert polypropylene mesh provides a strong and stable covering for the defect. Mobilization of adjacent skin flaps to provide covering for the mesh is desirabl...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1975-10-01 00:00:00
abstract：BACKGROUND:The heterogeneous nature of carcinoid tumors makes it difficult to develop a standardized treatment strategy for the primary tumor itself and for probable liver metastases. However, prolongation of the 5-year survival rate (5-ysr) and amelioration of the incapacitating symptoms after resection of the primary...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1067/msy.2001.110426
更新日期：2001-02-01 00:00:00
abstract：BACKGROUND:The management of patients with a complete clinical response after neoadjuvant therapy for rectal adenocarcinoma is controversial. Those who advocate for resection point out the inaccuracy of N-staging with current imaging modalities. The objective of this study is to determine the impact of residual nodal i...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2019.03.026
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:Preoperative noninvasive localization studies of the neck and mediastinum are beneficial before reoperation. However, the role of selective venous sampling (SVS) for parathyroid hormone (PTH) in reoperative parathyroid surgery has never been clearly defined. The purpose of this study was to evaluate the accu...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1067/msy.2002.128477
更新日期：2002-12-01 00:00:00
abstract：:A patient's condition was initially diagnosed as constrictive pericarditis, but an echocardiogram revealed the presence of an intracardiac tumor. The tumor was a slow-growing leiomyosarcoma that originated in the left internal iliac vein, extended into the inferior vena cava, and reached the right ventricle. This tumo...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1981-05-01 00:00:00
abstract：:Primary aortocolic fistulas are a rare but lethal complication of aortic or iliac aneurysms. A case of fistula between a nonaneurysmal aortic bifurcation and sigmoid colon caused by an ingested chicken bone is presented. This cause of rectal bleeding, which has never been described, might have been suspected after car...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1988-04-01 00:00:00
abstract：:The results of a 5-year experience with use of intraoperative radiation therapy (IORT) in the management of locally advanced bile duct carcinoma are presented. Fifteen patients received IORT doses between 5 and 20 Gy for localized disease, which was either primary and resected with microscopic residual (2 patients), p...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1989-06-01 00:00:00
abstract：BACKGROUND:Adrenal venous sampling (AVS) is used in the workup of primary hyperaldosteronism (PA). The purpose of this study was to determine the success rate of AVS and to examine the decision-making process after "less than ideal" AVS. METHODS:A total of 60 patients underwent 62 AVS for PA. Biochemical evidence of a...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2006.07.026
更新日期：2006-12-01 00:00:00
abstract：:Forty-five patients with varying biliary pathology were injected with one gram of intramuscular cefazolin sodium prior to surgery. Serum, gallbladder bile, and common duct bile levels were measured. The type of biliary disease did not influence serum levels (mean, 29 mug per milliliter) which reached a peak one hour a...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1977-04-01 00:00:00
abstract：BACKGROUND:Adhesion of polymorphonuclear leukocytes (PMNs) to endothelial cells is mediated partially by CD11/CD18 integrins. The purpose of this study was to define (1) the response of PMNs to anti-CD18 monoclonal antibody binding, and (2) the mechanism responsible for anti-CD18 monoclonal antibody-mediated decreases ...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1992-08-01 00:00:00
abstract：BACKGROUND:Peritoneal carcinomatosis has been regarded as a uniformly lethal clinical entity. Recently, dose-intensive treatments combining cytoreductive surgery and intraperitoneal chemotherapy have resulted in long-term survival in selected patients. METHODS:This article reports the morbidity and mortality associate...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：BACKGROUND:Bacterial translocation has been implicated in the alteration of the immune response after shock and trauma. This study examined the effect of bacterial translocation on myelopoiesis after hemorrhagic shock in germ-free and conventional rats. METHODS:Awake, unrestrained germ-free and conventional rats were ...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
