Clinical Efficiency of Topical Calcipotriol/Betamethasone Treatment in Psoriasis Relies on Suppression of the Inflammatory TNFα - IL-23 - IL-17 Axis.

abstract：:Three-day-old rat skins were treated either by the freezing--thawing method or by the tetraphenylboron technique. After the former procedure, keratohyalin granules were solubilized, leaving empty spaces with an electron-dense or less dense rim. Particles roughly 200 A in diameter, which were either electron-dense or l...

journal_title：Acta dermato-venereologica

authors： Tezuka T,Hirai R

更新日期：1978-01-01 00:00:00

abstract：:Scalp psoriasis is associated with hair loss and an increased telogen/anagen ratio. Topical treatment of scalp psoriasis (with corticosteroids, dithranol or tar) results in decreased scaling, induration and erythema of the plaques. Calcipotriol is effective in the treatment of psoriasis vulgaris. However, the potent g...

journal_title：Acta dermato-venereologica

authors： Kuijpers AL,van Baar HM,van Gasselt MW,van de Kerkhof PC

更新日期：1995-09-01 00:00:00

abstract：:Papillon-Lefèvre syndrome is an autosomal recessive disorder characterized by palmoplantar hyperkeratosis and aggressive periodontitis. The aim of the study was to identify underlying cathepsin C mutations in 39 subjects with Papillon-Lefèvre syndrome and to explore any phenotypic associations. Genotyping and mutation...

journal_title：Acta dermato-venereologica

authors： Ullbro C,El-Samadi S,Boumah C,Al-Yousef N,Wakil S,Twetman S,Alfadley A,Thestrup-Pedersen K,Meyer B

更新日期：2006-01-01 00:00:00

abstract：:The prevalence of melanocytic naevi in children correlates with sun exposure and may serve as an objective population risk indicator of future melanoma incidence. The aim was to investigate if mobile teledermatology could offer a valid methodology compared with standard manual, face-to-face counting of naevi on the ba...

journal_title：Acta dermato-venereologica

authors： Karlsson MA,Lindelöf B,Wahlgren CF,Wiklund K,Rodvall Y

更新日期：2015-03-01 00:00:00

abstract：:The incidence of malignant melanoma of the skin has increased rapidly among white people during the last decade. Although the pathogenesis of malignant melanoma is not clear, epidemiologic data and experimental work indicates that ultraviolet (UV) radiation plays a critical role in tumorigenesis. Recent data implicate...

journal_title：Acta dermato-venereologica

authors： Reinhold U,Biltz H,Bayer W,Schmidt KH

更新日期：1989-01-01 00:00:00

abstract：:A dermatitis occurring during the treatment of mycosis fungoides with A vitamin analogues (13-cis-retinoic acid and etretinate) and mimicking a progression of the disease is described. It is considered to be a skin reaction due to the treatment. Its benign nature is revealed by histology showing a lymphocytic infiltra...

journal_title：Acta dermato-venereologica

authors： Molin L,Thomsen K,Volden G,Lange Wantzin G

更新日期：1985-01-01 00:00:00

abstract：:Eosinophilic pustular folliculitis is a rare dermatosis. Recently, in addition to oral indomethacin, other treatments have been applied for eosinophilic pustular folliculitis. The aim of this study was to assess the effectiveness of various therapies encompassing conventional to newly applied drugs for eosinophilic pu...

journal_title：Acta dermato-venereologica

authors： Fukamachi S,Kabashima K,Sugita K,Kobayashi M,Tokura Y

更新日期：2009-01-01 00:00:00

abstract：:A 36-year-old Japanese woman with an extraskeletal osteochondroma in the left thumb is reported. A roentgenogram showed a calcified tumor, located at the distal portion of the left distal phalanx, which mimicked the fourth phalangeal bone. The pathogenesis might in this case be hamartomatous. ...

journal_title：Acta dermato-venereologica

authors： Nogita T,Kawakami M

更新日期：1992-08-01 00:00:00

abstract：:The aim of this study was to investigate the suitability and effectiveness of heliotherapy in moderate or severe atopic dermatitis in adults in the Canary Islands. A total of 216 patients participated on 6 different 2- or 3-week heliotherapy trips. Using the Severity Scoring of Atopic Dermatitis Index (SCORAD), the se...

journal_title：Acta dermato-venereologica

authors： Autio P,Komulainen P,Larni HM

更新日期：2002-01-01 00:00:00

abstract：:The regulation of IgE production in B lymphocytes of patients with atopic dermatitis by interleukin-4 (IL-4) and interferon-gamma (IFN-gamma) was studied. IL-4 stimulated IgE production in vitro in B-cells of healthy donors and of children with atopic dermatitis, but had only a marginal effect on the high basal level ...

journal_title：Acta dermato-venereologica

authors： Gruner S,Liebenthal C,Heusser C,Brinkmann V,Zwirner A,Reinicke C,Harnack K,Sönnichsen N,Volk HD

更新日期：1991-01-01 00:00:00

abstract：:Skin microdialysis is an established method for in vivo sample collection from the extracellular fluid space. This method has been extensively used in studies of inflammatory reactions in the skin of animals and humans. Skin microdialysis consists of the implantation of semi-permeable probes into the upper dermis, per...

journal_title：Acta dermato-venereologica

authors： Hersini KJ,Melgaard L,Gazerani P,Petersen LJ

更新日期：2014-09-01 00:00:00

abstract：:In patients with atopic dermatitis, the skin is often 'dry' on non-eczematous areas, and feels rough to the touch. In the scanning electron microscope (SEM) this roughness corresponds to a change in the skin surface, from regular major and minor furrows into a coarse and irregular pattern. In the present study the top...

journal_title：Acta dermato-venereologica

authors： Linde YW,Bengtsson A,Lodén M

更新日期：1989-01-01 00:00:00

abstract：:We set out to show that the assumption is incorrect that continuous treatment with cyclosporin is necessary in psoriasis, as this tenet forms a basis for current recommended treatment regimens. Sixty patients with mild to moderate plaque psoriasis were allocated at random to treatment with oral cyclosporin 5 mg/kg/day...

journal_title：Acta dermato-venereologica

authors： Levell NJ,Shuster S,Munro CS,Friedmann PS

更新日期：1995-01-01 00:00:00

abstract：:The effect of a protective cream was tested in a new tandem repeated irritation test with tandem application of 0.5% sodium lauryl sulphate (SLS) and undiluted toluene. The irritants were applied twice daily for 30 min to the ventral forearms of 20 volunteers. Irritant cutaneous reactions were quantified by a visual s...

journal_title：Acta dermato-venereologica

authors： Wigger-Alberti W,Spoo J,Schliemann-Willers S,Klotz A,Elsner P

更新日期：2002-01-01 00:00:00

abstract：:The validity of Laser Doppler Flowmetry for measurements of changes in skin blood flow rates during orthostatic manoeuvres was evaluated. Fifteen healthy subjects were investigated. Relative skin blood flow rates on the dorsum of the hand were measured during stepwise raising and lowering of the arm in 10 cm increment...

journal_title：Acta dermato-venereologica

authors： Petersen LJ,Sindrup JH

更新日期：1990-01-01 00:00:00

abstract：:Bullous pemphigoid is an autoimmune subepithelial disease characterised by pruritus followed by urticarial plaques and finally bullae on the skin and mucosa. Drug-associated bullous pemphigoid (DABP) is a term used to describe instances of bullous pemphigoid demonstrating clinical, histological, or immunopathological ...

journal_title：Acta dermato-venereologica

authors： Verheyden MJ,Bilgic A,Murrell DF

更新日期：2020-08-17 00:00:00

abstract：:Botulinum toxin is used in various fields of medicine, including in the treatment of hyperhidrosis. Three products containing botulinum toxin are commercially available in Sweden; Botox, Dysport and Neurobloc. In the literature dose-response has varied with respect to these 3 products. We hypothesized that the dilutio...

journal_title：Acta dermato-venereologica

authors： Rystedt A,Swartling C,Naver H

更新日期：2008-01-01 00:00:00

abstract：:Pigmented basal cell carcinomas can be difficult to distinguish clinically from melanoma. Dermoscopy has proven to be useful in the differential diagnosis of the two tumour types. SIAscopy (Spectrophotometric intracutaneous analysis) is a fairly new technique of imaging pigmented skin lesions that has been presented p...

journal_title：Acta dermato-venereologica

authors： Terstappen K,Larkö O,Wennberg AM

更新日期：2007-01-01 00:00:00

abstract：:Two patients with multiple angiokeratomas on genitalia and thighs, one with Fabry's disease and one with Fordyce's disease, were treated with copper vapour laser light of 578 nm wavelength. The result was desirable, with destruction and disappearance of the lesions and minimal scarring and posttreatment hyper- or hypo...

journal_title：Acta dermato-venereologica

authors： Lapins J,Emtestam L,Marcusson JA

更新日期：1993-04-01 00:00:00

abstract：:Retinoid transfer into breast milk was studied in a psoriatric woman receiving oral acitretin at a dosage of 40 mg once daily. Concentrations of the parent compound and its main metabolite, 13-cis acitretin, were measured in serum and mature milk during the initial nine days of therapy, using reverse-phase high perfor...

journal_title：Acta dermato-venereologica

authors： Rollman O,Pihl-Lundin I

更新日期：1990-01-01 00:00:00

abstract：:Actinomycotic mycetomas usually respond slowly to treatment with antibiotics. In an attempt to hasten clinical resolution, we used a 2-step regimen consisting of an intensive phase of therapy with penicillin, gentamycin and co-trimoxazole for 5-7 weeks, followed by maintenance therapy with amoxicillin and co-trimoxazo...

journal_title：Acta dermato-venereologica

authors： Ramam M,Garg T,D'Souza P,Verma KK,Khaitan BK,Singh MK,Banerjee U

更新日期：2000-09-01 00:00:00

abstract：:Only animal experiments have been published regarding the possible effect of penicillamine treatment on mineral balance. We examined 35 patients with a diagnosis of systemic sclerosis treated with penicillamine, in comparison with 10 patients with systemic sclerosis treated with other collagen inhibitors (glutamine, h...

journal_title：Acta dermato-venereologica

authors： Hagdrup H,Serup J,Tvedegaard E

更新日期：1983-01-01 00:00:00

abstract：:The role of cell-mediated immunity in controlling Basal Cell Carcinoma (BCC) growth was studied by measuring the transformation of lymphocytes when challenged in vitro with aqueous extracts of the patients' BCCs and of control skin. Tests were carried out in the presence of autologous and heat-treated plasma. Three pa...

journal_title：Acta dermato-venereologica

authors： Raffle EJ,MacLeod TM,Hutchinson F

更新日期：1981-01-01 00:00:00

abstract：:Retinol and proguanil are metabolised by the same family of hepatic cytochrome P450, i.e. CYP2C. We used proguanil as a probe to study CYP2C activity, and by implication retinol metabolism, in psoriasis. In vitro studies showed that retinol competitively inhibited the hepatic metabolism of proguanil to cycloguanil. Pr...

journal_title：Acta dermato-venereologica

authors： Helsby NA,Ward SA,Parslew RA,Friedmann PS,Rhodes LE

更新日期：1998-03-01 00:00:00

abstract：:Five patients with a histopathologically confirmed diagnosis of pityriasis lichenoides were treated with PUVA or irradiated with a light source emitting UVB and UVA, without prior intake of psoralens. All patients showed a good response to treatment. Long-term follow up showed that patients remained free of lesions du...

journal_title：Acta dermato-venereologica

authors： Boelen RE,Faber WR,Lambers JC,Cormane RH

更新日期：1982-01-01 00:00:00

abstract：:Both spontaneous and inducible forms of chronic urticaria pose a significant economic burden and have an adverse effect on patients' quality of life. The international guidelines and US practice parameters for the diagnosis and management of chronic urticaria both recommend performing a thorough patient history and ph...

journal_title：Acta dermato-venereologica

authors： Beck LA,Bernstein JA,Maurer M

更新日期：2017-02-08 00:00:00

abstract：:A 39-year-old man presented with multiple basaloid follicular hamartomas involving the right side of his body in a systematized pattern following Blaschko's lines. His right leg was 22.5 cm shorter than the left, and rudimentary pre-axial polydactyly was noted on the left hand and the right foot. The teeth of the righ...

journal_title：Acta dermato-venereologica

authors： Happle R,Tinschert S

更新日期：2008-01-01 00:00:00

abstract：:Normal skin and psoriatic lesions from 35 patients were investigated immunohistochemically with regard to the CD1a+ cell population (Langerhans' cells and indeterminate cells) in the epidermis as well as in the dermal infiltrate. In the normal-appearing skin, we found the regularly typical pattern of CD1a+ dendritic c...

journal_title：Acta dermato-venereologica

authors： Bieber T,Braun-Falco O

更新日期：1989-01-01 00:00:00

abstract：:Blood flow in subcutaneous tissue of the lower leg decreased by 45% on changing from recumbency to the sitting position in patients suffering from chronic venous insufficiency. When walking, blood flow increased significantly to values near those measured during resting recumbency. A conventional elastic compression b...

journal_title：Acta dermato-venereologica

authors： Kristensen JK,Sindrup JH,Jelstrup Petersen L,Peters K,Danielsen L

更新日期：1991-01-01 00:00:00

abstract：:The ultrastructure of dermal connective tissue in two patients suffering from fibrodysplasia ossificans progressiva (syn myositis o.p.) was studied. The disorder starts with soft tissue swelling which subsequently ossify. The connective tissue of various organs may be affected. No defects in calcium metabolism have be...

journal_title：Acta dermato-venereologica

authors： Hentzer B,Kobayasi T,Asboe-Hansen G

更新日期：1977-01-01 00:00:00