Trends of HIV-1 Subtypes Among Young People in Hangzhou, China.

abstract：:Retroviruses have been suggested as possible pathogenic factors in multiple sclerosis (MS), supported by the observation that endogenous retroviruses are activated in MS patients. Different members of the herpes family of which several are neurotropic have also been suggested as factors in MS pathogenesis. Further, in...

journal_title：AIDS research and human retroviruses

authors： Brudek T,Christensen T,Hansen HJ,Bobecka J,Møller-Larsen A

更新日期：2004-04-01 00:00:00

abstract：:Mitochondrial impairment is reported in HIV-infected children receiving antiretroviral therapy (ART), as well as those naive to ART. Whether mitochondrial function recovers with early initiation of ART and sustained viral suppression on long-term ART is unclear. In this study, we evaluate mitochondrial markers in well...

journal_title：AIDS research and human retroviruses

authors： Shen J,Liberty A,Shiau S,Strehlau R,Pierson S,Patel F,Wang L,Burke M,Violari A,Coovadia A,Abrams EJ,Arpadi S,Foca M,Kuhn L

更新日期：2020-01-01 00:00:00

abstract：:Elderly people living with HIV are increasing. At present in the United States, nearly half of newly diagnosed HIV-infected people are aged >50 years. Diagnosis and treatment of HIV-infected elderly patients tends to be delayed by several health care factors as several life-threatening diseases are common in elderly p...

journal_title：AIDS research and human retroviruses

authors： Bhatta M,Nandi S,Dutta N,Dutta S,Saha MK

更新日期：2020-06-01 00:00:00

abstract：:Data reporting sexually transmitted infection (STI) incidence rates among HIV-negative U.S. men who have sex with men (MSM) are lacking. In addition, it is difficult to analyze the effect of STI on HIV acquisition given that sexual risk behaviors confound the relationship between bacterial STIs and incident HIV. The I...

journal_title：AIDS research and human retroviruses

authors： Kelley CF,Vaughan AS,Luisi N,Sanchez TH,Salazar LF,Frew PM,Cooper HL,Diclemente R,del Rio C,Sullivan PS,Rosenberg ES

更新日期：2015-06-01 00:00:00

abstract：:Surveillance of drug resistance mutations in antiretroviral-experienced HIV(+) patients may provide useful information regarding options available for rescue interventions. All resistance tests performed from 1999 to 2005 on antiretroviral-experienced individuals at one reference laboratory in Madrid were examined. On...

journal_title：AIDS research and human retroviruses

authors： de Mendoza C,Garrido C,Corral A,Ramírez-Olivencia G,Jiménez-Nacher I,Zahonero N,Gonzalez-Lahoz J,Soriano V

更新日期：2007-07-01 00:00:00

abstract：:The national incidence of epidemic Kaposi sarcoma (KS) has decreased dramatically since the availability of combined antiretroviral therapy. Despite national trends, we continue to see admissions for KS. Electronic medical records were queried to identify patients with HIV who were admitted with active KS between 2010...

journal_title：AIDS research and human retroviruses

authors： Kasturia SE,Gunthel C,Zeng C,Nguyen ML

更新日期：2017-06-01 00:00:00

abstract：:Lectins with specificity for terminal mannose residues and anti-mannan antibodies neutralize HIV-1 infection in vitro. This is assumed to be caused by binding of the agents to the viral glycoproteins. In this study we show that one such agent, the Galanthus nivalis lectin (GNA), also blocks infection at the target cel...

journal_title：AIDS research and human retroviruses

authors： Hammar L,Hirsch I,Machado AA,De Mareuil J,Baillon JG,Bolmont C,Chermann JC

更新日期：1995-01-01 00:00:00

abstract：:The majority of AIDS patients will experience some degree of dementia induced by human immunodeficiency virus (HIV-1). In this study, we report that treatment of human brain tissue with envelope gp120 of HIV-1 did not cause neuronal death but did cause astrocyte alterations and/or death. Human astrocyte cultures showe...

journal_title：AIDS research and human retroviruses

authors： Pulliam L,West D,Haigwood N,Swanson RA

更新日期：1993-05-01 00:00:00

abstract：:Despite the considerable progress that has been made in identifying cellular factors and pathways that contribute to establishment and maintenance of the latent HIV reservoir, it remains the major obstacle to eradicating this virus. Most recently, noncoding genes have been implicated in regulation of HIV expression. I...

journal_title：AIDS research and human retroviruses

authors： Heinson AI,Woo J,Mukim A,White CH,Moesker B,Bosque A,Spina CA,Woelk CH,Macarthur BD,Beliakova-Bethell N

更新日期：2020-11-10 00:00:00

abstract：:In this study, HIV strains circulating among military personnel were characterized, in Malabo, the capital city of Equatorial Guinea. One sample was found to be HIV-2 group A while a high degree of genetic diversity was recorded in the pol region of 41 HIV-1-positive samples. CRF02_AG accounted for 53.7% of the strain...

journal_title：AIDS research and human retroviruses

authors： Djoko CF,Wolfe ND,Vidal N,Tamoufe U,Montavon C,LeBreton M,Pike BL,Fair J,Mbacham WF,Benito A,Rimoin AW,Saylors K,Mpoudi-Ngole E,Grillo MP,Peeters M

更新日期：2010-09-01 00:00:00

abstract：:The HIV-1 envelope glycoprotein complex (Env) can be stabilized by the introduction of a disulfide bond between the gp120 and gp41 subunits. The resulting protein is monomeric, but trimerization can be improved by the introduction of a single helix-breaking residue at the conserved Ile559 site in the N-terminal heptad...

journal_title：AIDS research and human retroviruses

authors： Sanders RW,Busser E,Moore JP,Lu M,Berkhout B

更新日期：2004-07-01 00:00:00

abstract：:We aimed to determine the prevalence of a prolonged QTc interval in HIV-infected patients and its related factors through an observational study of a cohort of asymptomatic HIV-infected outpatients. All patients underwent a standard 12-lead electrocardiogram and a transthoracic echocardiogram. Prolonged QTc was consid...

journal_title：AIDS research and human retroviruses

authors： Moreno T,Pérez I,Isasti G,Cabrera F,Santos J,Palacios R

更新日期：2013-09-01 00:00:00

abstract：:The use of ritonavir as a protease inhibitor boost is rare in sub-Saharan Africa because a heat-stable formula is not available. We report the results of an open-label pilot trial with unboosted atazanavir in combination with lamivudine and didanosine as first-line therapy conducted in Senegal. Treatment-naive HIV-1 i...

journal_title：AIDS research and human retroviruses

authors： Landman R,Diallo MB,Gueye NF,Kane CT,Mboup S,Fall MB,Ndiaye B,Peytavin G,Bennai Y,Benalycherif A,Girard PM,Sow PS

更新日期：2010-05-01 00:00:00

abstract：:In Taiwan, sexual transmission is responsible for most HIV-1 infections with two dominant subtypes, subtype B and CRF01_AE, distributing among homosexual and heterosexual groups, respectively. Recently, intravenous drug use has become an emerging route of HIV-1 transmission and contributed to a significant increase of...

journal_title：AIDS research and human retroviruses

authors： Chang SY,Sheng WH,Lee CN,Sun HY,Kao CL,Chang SF,Liu WC,Yang JY,Wong WW,Hung CC,Chang SC

更新日期：2006-11-01 00:00:00

abstract：:We have previously used immunotoxins to select for HIV-1 variant cells that transcribe HIV at extremely low levels and fail to produce HIV proteins. Further observation of one of these variants (E9) demonstrated spontaneous in vitro activation of HIV production. The mechanism of activation is different from that of U1...

journal_title：AIDS research and human retroviruses

authors： Fang H,Pincus S

更新日期：1999-10-10 00:00:00

abstract：:Stavudine (d4T) has been associated with lipoatrophy and hyperlactatemia. In recent studies, d4T has also been related to both hypercholesterolemia and hypertriglyceridemia. Replacing d4T with another nucleoside analogue such as abacavir (ABC) may reduce lactate levels and improve lipoatrophy in the long term. However...

journal_title：AIDS research and human retroviruses

authors： García-Benayas T,Blanco F,Alcolea A,Cruz JJ,González-Lahoz J,Soriano V

更新日期：2004-12-01 00:00:00

abstract：:In this study HIV-1 subtype C-infected adults demonstrated higher purifying selection on their viral populations in reverse transcriptase (RT) than infected children. This difference is likely explained by more mature cytotoxic T-lymphocyte responses in adults, which may have implications for the development of drug r...

journal_title：AIDS research and human retroviruses

authors： Saravanan S,Gomathi S,Kausalya B,Boobalan J,Murugavel KG,Balakrishnan P,Mothi SN,Solomon SS,Kumarasamy N,Selvamuthu P,Solomon S,Smith DM

更新日期：2015-06-01 00:00:00

abstract：:The chemokine receptor CXCR4 is the main coreceptor used by T-tropic X4 HIV-1 strains to infect its target T cells. It has been proven that the CXCR4 expression level in T cells is strongly up-regulated by interleukin (IL)-4, a Th2-type cytokine that is secreted preferentially in HIV-infected patients in a later stage...

journal_title：AIDS research and human retroviruses

authors： Princen K,Hatse S,Vermeire K,Bridger GJ,Skerlj RT,De Clercq E,Schols D

更新日期：2003-12-01 00:00:00

abstract：:HIV-1 group N (HIV-1/N) remains rare and mainly restricted to Cameroon. In this study, we report a new HIV-1/N infected case identified during routine HIV screening activities in Yaounde. The genetic characterization of the near full-length genome of this virus strain revealed that it is genetically distinct to all HI...

journal_title：AIDS research and human retroviruses

authors： Tagnouokam Ngoupo PA,Sadeuh-Mba SA,De Oliveira F,Ngo-Malabo ET,Ngono L,Plantier JC,Kfutwah A,Njouom R

更新日期：2018-07-01 00:00:00

abstract：:Studies have demonstrated that HIV-1 isolated from subjects experiencing virologic failure on stavudine (d4T)-containing regimens often contains thymidine analog mutations (TAMs), consisting of reverse transcriptase (RT) mutations M41L, D67N, K70R, L210W, T215Y/F, and K219Q/E, previously associated only with zidovudin...

journal_title：AIDS research and human retroviruses

authors： Ross L,Scarsella A,Raffanti S,Henry K,Becker S,Fisher R,Liao Q,Hirani A,Graham N,St Clair M,Hernandez J,NZT40012 Study Team.

更新日期：2001-08-10 00:00:00

abstract：:Human T cell leukemia virus type-1 (HTLV-1) is prevalent worldwide with foci of high prevalence. However, to date no effective vaccine or drug against HTLV-1 infection has been developed. In efforts to define the role of antibodies in the control of HTLV-1 infection, we capitalized on the use of our previously defined...

journal_title：AIDS research and human retroviruses

authors： Tanaka Y,Takahashi Y,Tanaka R,Kodama A,Fujii H,Hasegawa A,Kannagi M,Ansari AA,Saito M

更新日期：2014-06-01 00:00:00

abstract：:Abstract The effectiveness of any biomedical prevention technology relies on both biological efficacy and behavioral adherence. Microbicide trials have been hampered by low adherence, limiting the ability to draw meaningful conclusions about product effectiveness. Central to this problem may be an inadequate conceptua...

journal_title：AIDS research and human retroviruses

authors： Morrow KM,Fava JL,Rosen RK,Vargas S,Shaw JG,Kojic EM,Kiser PF,Friend DR,Katz DF,Project Link Study Team.

更新日期：2014-01-01 00:00:00

abstract：:To gain more insight into the processes leading to HIV-1 Env-induced cell death, we aim to coexpress stably wild-type and relevant mutant variants of both HIV-1 Env and human CD4 in lymphocyte cell lines. Here we report on the generation and characterization of several cell lines inducibly or constitutively expressing...

journal_title：AIDS research and human retroviruses

authors： Krüger U,Pfeiffer T,Bosch V

更新日期：1996-06-10 00:00:00

abstract：:Despite dramatic reduction of the levels of human immunodeficiency virus type I (HIV-1) virions in blood and seminal plasma of infected patients, highly active antiretroviral therapy (HAART) does not eradicate HIV-1. Three patients, with less than 50 copies/ml of plasma viral RNA, were enrolled in this eradication pro...

journal_title：AIDS research and human retroviruses

authors： Nunnari G,Leto D,Sullivan J,Xu Y,Mehlman KE,Kulkosky J,Pomerantz RJ

更新日期：2005-09-01 00:00:00

abstract：:HIV-1 genital shedding is associated with increased HIV-1 transmission risk. Inflammation and ulceration are associated with increased shedding, while highly active antiretroviral therapy (HAART) has been shown to have a protective effect. We sought to examine the impact of cervical biopsies, a routine component of ce...

journal_title：AIDS research and human retroviruses

authors： Woo VG,Liegler T,Cohen CR,Sawaya GF,Smith-McCune K,Bukusi EA,Huchko MJ

更新日期：2013-07-01 00:00:00

abstract：:In Western countries, HTLV-1 infection is recognized mainly among foreigners coming from endemic areas. In contrast, HTLV-2 is found predominantly in native intravenous drug users (IDUs). Spain has experienced a large wave of immigration, which could have influenced the current prevalence and distribution of HTLV-1 an...

journal_title：AIDS research and human retroviruses

authors： Toro C,Aguilera A,Caballero E,Tuset C,Alvarez P,García-Campello M,Rodríguez-Iglesias M,de Lejarazu RO,Eiros J,Rodriguez C,del Romero J,Benito R,Calderón E,Santana O,Amor A,Gómez-Hernando C,García J,Soriano V

更新日期：2007-09-01 00:00:00

abstract：:Persons living with HIV (PLWH) with substance use disorders (SUD) remain a population difficult to engage in HIV care. Project HOPE (Hospital Visits as an Opportunity for Prevention and Engagement), a randomized controlled trial testing patient navigation with/without contingency management for PLWH with SUD, aimed to...

journal_title：AIDS research and human retroviruses

authors： Summers NA,Colasanti JA,Feaster DJ,Armstrong WS,Rodriguez A,Jain MK,Jacobs P,Metsch LR,Del Rio C

更新日期：2020-05-01 00:00:00

abstract：:Epstein-Barr virus (EBV) infection is associated with Burkitt's lymphoma (BL) in normal individuals and immunoblastic B cell lymphomas in immunosuppressed or HIV-infected individuals. SCID mice reconstituted with human peripheral blood leukocytes (hu-PBL-SCID) from EBV-seropositive donors also may develop spontaneous ...

journal_title：AIDS research and human retroviruses

authors： Mosier DE,Picchio GR,Kirven MB,Garnier JL,Torbett BE,Baird SM,Kobayashi R,Kipps TJ

更新日期：1992-05-01 00:00:00

abstract：:Cessation of highly active antiretroviral therapy (HAART) in HIV-infected individual leads to a rebound of viral replication due to reactivation of a viral reservoir composed largely of latently infected memory CD4(+) T cells. Efforts to deplete this reservoir have focused on reactivation of transcriptionally silent l...

journal_title：AIDS research and human retroviruses

authors： Jamaluddin MS,Hu PW,Jan Y,Siwak EB,Rice AP

更新日期：2016-02-01 00:00:00

abstract：:The structure of the Vpu protein of human immunodeficiency virus type 1 (HIV-1) is composed of a short Nterminal domain (NTD), a transmembrane domain (TM), and a cytoplasmic domain (CD). Previous studies have shown that the Vpu protein from subtype B HIV-1 is transported predominantly to the rough endoplasmic reticulu...

journal_title：AIDS research and human retroviruses

authors： Pacyniak E,Gomez ML,Gomez LM,Mulcahy ER,Jackson M,Hout DR,Wisdom BJ,Stephens EB

更新日期：2005-05-01 00:00:00