EBV-induced human B cell lymphomas in hu-PBL-SCID mice.

abstract：:In recent years, increasing numbers of patients infected with HIV-1 non-B subtypes have been treated with modern antiretroviral regimens. Therefore, a better knowledge of HIV drug resistance in non-B strains is crucial. Thus, we compared the mutational pathways involved in drug resistance among the most common non-B s...

journal_title：AIDS research and human retroviruses

authors： Santoro MM,Alteri C,Ronga L,Flandre P,Fabeni L,Mercurio F,D'Arrigo R,Gori C,Palamara G,Bertoli A,Forbici F,Salpini R,Boumis E,Tozzi V,Visco-Comandini U,Zaccarelli M,Van Houtte M,Pattery T,Narciso P,Antinori A,Cecc

更新日期：2012-10-01 00:00:00

abstract：:The incidence of anal cancer is increased in HIV-infected patients compared with the general population. Risk factors associated with the anal cancer precursor, high-grade squamous intraepithelial lesion (HSIL), have not been extensively studied in an urban black population with late-stage HIV disease. We performed a ...

journal_title：AIDS research and human retroviruses

authors： Frank M,Lahiri CD,Nguyen ML,Mehta CC,Mosunjac M,Flowers L

更新日期：2018-07-01 00:00:00

abstract：:To gain more insight into the processes leading to HIV-1 Env-induced cell death, we aim to coexpress stably wild-type and relevant mutant variants of both HIV-1 Env and human CD4 in lymphocyte cell lines. Here we report on the generation and characterization of several cell lines inducibly or constitutively expressing...

journal_title：AIDS research and human retroviruses

authors： Krüger U,Pfeiffer T,Bosch V

更新日期：1996-06-10 00:00:00

abstract：:Sexual transmission of human immunodeficiency virus provides an efficient mode for virus spread and poses unique challenges to vaccine developers. Host and viral factors that affect transmission have been studied by epidemiological approaches in the human population, and some of these factors have been modeled with ex...

journal_title：AIDS research and human retroviruses

authors： Pauza CD,Horejsh D,Wallace M

更新日期：1998-04-01 00:00:00

abstract：:Partial sequences of HIV-1 polymerase from 185 patients, 141 ARV experienced and 44 naive, of gag (p24) and env (C2V3) from a subset of naive cases were evaluated in São Paulo, Brazil. Antiretroviral resistance mutations were detected in 4% of 26 recently (<2 years) infected patients. Polymorphisms at the protease gen...

journal_title：AIDS research and human retroviruses

authors： Brígido LF,Franco HM,Custódio RM,Oliveira CA,P Ferreira JL,Eira M,Bergel F,Araújo F,Carvalheiro JR,Rodrigues R

更新日期：2005-07-01 00:00:00

abstract：:Using blood samples from primary HIV-1 infection (PHI) patients obtained in Lyon, France, we characterized the newly transmitted HIV-1 variants in this area during the 1992-1996 period. As PHI samples allowed the precise timing of the transmission event, we were able to date the introduction of non-B subtypes or recom...

journal_title：AIDS research and human retroviruses

authors： Vachot L,Ataman-Onal Y,Terrat C,Durand PY,Ponceau B,Biron F,Verrier B

更新日期：2004-07-01 00:00:00

abstract：:Foamy viruses are a genus of complex retroviruses that infect a wide variety of mammals. However, a clear association with any disease process has yet to be proven for these viruses. A higher human seroprevalence was reported in African populations, perhaps due to exposure to simian foamy viruses (SFV) endemic in prim...

journal_title：AIDS research and human retroviruses

authors： Goepfert PA,Ritter GD Jr,Peng X,Gbakima AA,Zhang Y,Mulligan MJ

更新日期：1996-12-10 00:00:00

abstract：:It is known that the HTLV-I-transformed cell line MT4 releases chemotactic activity for monocytes spontaneously. The MT4 monocyte chemoattractant was purified to homogeneity and sequencing of 25 amino acids revealed identity with the C-C chemokine macrophage inflammatory protein-1 alpha (MIP-1 alpha/LD78). An anti-MIP...

journal_title：AIDS research and human retroviruses

authors： Bertini R,Luini W,Sozzani S,Bottazzi B,Ruggiero P,Boraschi D,Saggioro D,Chieco-Bianchi L,Proost P,van Damme J

更新日期：1995-01-01 00:00:00

abstract：:The HIV epidemic in Russia, one of the world's fastest growing, has been concentrated mostly among people who inject drugs (PWID). We sought to explore the epidemiology of the epidemic in St. Petersburg by sampling from the highest risk groups of PWID and men who have sex with men (MSM) and use viral sequencing data t...

journal_title：AIDS research and human retroviruses

authors： Dukhovlinova E,Masharsky A,Toussova O,Verevochkin S,Solovyeva T,Meringof M,Paintsil E,White E,Barbour R,Heimer R,Kozlov A

更新日期：2015-06-01 00:00:00

abstract：:An aqueous extract of Phyllanthus niruri (Euphorbiaceae) inhibited human immunodeficiency virus type-1 reverse transcriptase (HIV-1-RT). The inhibitor against HIV-1-RT in this plant was purified by combination of three column chromatographies, Sephadex LH-20, cellulose, and reverse-phase high-performance liquid chroma...

journal_title：AIDS research and human retroviruses

authors： Ogata T,Higuchi H,Mochida S,Matsumoto H,Kato A,Endo T,Kaji A,Kaji H

更新日期：1992-11-01 00:00:00

abstract：:HLA is one of the genetic factors that influence the clinical course of HIV-1 infection, and patients with HLA-B35 are prone to rapid disease progression. Nine viral epitopes that are recognized by cytotoxic T lymphocytes (CTLs) in an HLA-B35-restricted manner were determined. To examine how HIV-1 sequences are select...

journal_title：AIDS research and human retroviruses

authors： Kawana A,Tomiyama H,Takiguchi M,Shioda T,Nakamura T,Iwamoto A

更新日期：1999-08-10 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) spends a significant part of its life cycle as latent provirus in nonactivated cells. It induction requires mitogen stimulation. TPA treatment induces HIV-1 transcription by protein kinase C (PKC)-mediated activation of the cellular transcription factor NF-kB. PKC activation...

journal_title：AIDS research and human retroviruses

authors： Doppler C,Schalasta G,Amtmann E,Sauer G

更新日期：1992-02-01 00:00:00

abstract：:To help in the vaccine development, WHO-UNAIDS launched a program for the isolation and characterization of subtype C viruses, the most prevalent HIV-1 subtype in the world. Isolates were obtained from Brazil, China, India, Israel, and South Africa, countries in which these strains are circulating. In this study we ge...

journal_title：AIDS research and human retroviruses

authors： Sánchez-Merino V,Herrero CC,Amorin-Nink A,von Briesen H,López-Galíndez C,World Health Organization-UNAIDS Network for Isolation and Characterization.

更新日期：2003-01-01 00:00:00

abstract：:Cross-sectional estimation of HIV incidence could misclassify some established or chronic HIV infections as recent. Usually long-term nonprogressors, elite and viremic controllers, and individuals on ART contribute to misclassification. Local data on the false recent rate (FRR) could minimize misclassification during ...

journal_title：AIDS research and human retroviruses

authors： Moyo S,Kotokwe KP,Mohammed T,Boleo C,Mupfumi L,Chishala S,Tsalaile L,Bussmann H,Gaseitsiwe S,Musonda R,Makhema J,Baum M,Marlink R,Engelbrecht S,Essex M,Novitsky V

更新日期：2017-01-01 00:00:00

abstract：:HIV-1 infection causes functional defects in T cells. It also leads to a progressive reduction in numbers of such cells and both CD4+ and CD8+ cells have been reported to undergo apoptosis in culture. A corresponding reduction in B cells has not been described, but these cells are also functionally altered, with repor...

journal_title：AIDS research and human retroviruses

authors： Samuelsson A,Sönnerborg A,Heuts N,Cöster J,Chiodi F

更新日期：1997-08-10 00:00:00

abstract：:Eight HIV-2-infected Caucasian men living in the same geographical area in Gipuzkoa (northern Spain) have been identified in the last 5 years. HIV-2 infection in this area is uncommon, and no other cases of HIV-2 infection have been found after extensive testing for HIV-1/2 antibodies. Epidemiological data suggested a...

journal_title：AIDS research and human retroviruses

authors： Cilla G,Rodés B,Pérez-Trallero E,Arrizabalaga J,Soriano V

更新日期：2001-03-20 00:00:00

abstract：:A new model system is delineated that will enable study of CD4 cofactors and gp120 binding proteins other than CD4. We have previously described a nontransformed rat fibroblast cell line that can efficiently produce HIV-1 upon transfection with an HIV-1 infectious clone, in contrast to other nonhuman mammalian cell li...

journal_title：AIDS research and human retroviruses

authors： Mizrachi Y,Rubinstein A,Golodner M,Sakai K,Volsky DJ

更新日期：1996-09-20 00:00:00

abstract：:This prospective, open-label, multicenter trial evaluated the effects of once-weekly (qw) epoetin alfa on quality of life (QOL) and hemoglobin (Hb) levels in anemic human immunodeficiency virus (HIV)-infected adult receiving antiretroviral therapy. A total of 650 patients with Hb < or = 11 g/dl received epoetin alfa 4...

journal_title：AIDS research and human retroviruses

authors： Saag MS,Bowers P,Leitz GJ,Levine AM,Community HIV Anemia Management Protocol Sites (CHAMPS) Study Group.

更新日期：2004-10-01 00:00:00

abstract：:The feasibility and effectiveness of a hospital-based exercise-training program followed by a home-based program for improving fitness, strength, and changes in body composition in children and adolescents with HIV were evaluated. Subjects participated in nonrandomized 24-session, hospital supervised exercise training...

journal_title：AIDS research and human retroviruses

authors： Miller TL,Somarriba G,Kinnamon DD,Weinberg GA,Friedman LB,Scott GB

更新日期：2010-03-01 00:00:00

abstract：:The mechanisms responsible for the hematopoietic failure in human immunodeficiency virus type 1 (HIV-1)-infected patients are still unknown. Several findings indicate that the in vitro proliferative potential of precursor cells from AIDS patients is reduced. The changes seen in bone marrow (BM) morphology and the defe...

journal_title：AIDS research and human retroviruses

authors： Isgrò A,Mezzaroma I,Aiuti A,De Vita L,Franchi F,Pandolfi F,Alario C,Ficara F,Riva E,Antonelli G,Aiuti F

更新日期：2000-10-10 00:00:00

abstract：:The HIV-1 reverse transcriptase genes from 37 HIV-1-positive pregnant women attending an antenatal clinical in Soweto, South Africa were sequenced and analyzed for the presence of drug resistance mutations. All women were antiretroviral drug naive, but were being screened as potential participants in clinical trials o...

journal_title：AIDS research and human retroviruses

authors： Pillay C,Bredell H,McIntyre J,Gray G,Morris L

更新日期：2002-05-20 00:00:00

abstract：:We report one or more HIV resistance mutations in 81.81% of the 33 antiretroviral treatment-experienced study participants with evidence of virologic failure, with M184V being the most commonly observed resistance mutation (69.7%). Two out of four participants with protease inhibitors (PI) experience harbored multiple...

journal_title：AIDS research and human retroviruses

authors： Sen S,Tripathy SP,Patil AA,Chimanpure VM,Paranjape RS

更新日期：2007-10-01 00:00:00

abstract：:Primary isolates of human immunodeficiency virus type 1 (HIV-1) were obtained by coculture of peripheral blood lymphocytes (PBLs) from HIV-1-infected people with PBLs from uninfected donors. These viral stocks tend to be resistant to neutralization/inactivation by soluble CD4 (sCD4). When these stocks were passed thro...

journal_title：AIDS research and human retroviruses

authors： Orloff SL,Bandea CI,Kennedy MS,Allaway GP,Maddon PJ,McDougal JS

更新日期：1995-03-01 00:00:00

abstract：:Dendritic cells (DCs) are important mediators of the immune response against HIV and yet blood DC numbers fall substantially during HIV infection. Here we report that blood levels of the DC-tissue tropic chemokines monocyte chemotactic protein (MCP-1/CCL2), macrophage inflammatory proteins (MIP-3α/CCL20), and MIP-3β/C...

journal_title：AIDS research and human retroviruses

authors： Fontaine J,Poudrier J,Roger M

更新日期：2011-06-01 00:00:00

abstract：:Accurate methods for cross-sectional incidence estimation are needed for HIV prevention research. The Limiting Antigen Avidity (LAg-Avidity) assay has been marketed by two vendors, Maxim Biomedical and Sedia BioSciences Corporation. Performance differences between the two versions of the assay are unknown. We tested a...

journal_title：AIDS research and human retroviruses

authors： Schlusser KE,Konikoff J,Kirkpatrick AR,Morrison C,Chipato T,Chen PL,Munjoma M,Eshleman SH,Laeyendecker O

更新日期：2017-06-01 00:00:00

abstract：:Genotype-based algorithms are valuable tools for the identification of patients eligible for CCR5 inhibitors administration in clinical practice. Among the available methods, geno2pheno[coreceptor] (G2P) is the most used online tool for tropism prediction. This study was conceived to assess if the combination of G2P p...

journal_title：AIDS research and human retroviruses

authors： Montagna C,De Crignis E,Bon I,Re MC,Mezzaroma I,Turriziani O,Graziosi C,Antonelli G

更新日期：2014-12-01 00:00:00

abstract：:Simian immunodeficiency virus (SIV) variant SIVsmmPBj14 is unique in producing an acutely lethal enteropathic syndrome in pigtail macaques. To determine whether the nature of the PBj14 disease would be attenuated by decreasing virus input and to relate tissue virus burden to the severity of disease, we infected pigtai...

journal_title：AIDS research and human retroviruses

authors： O'Neil SP,Mossman SP,Maul DH,Hoover EA

更新日期：1999-01-20 00:00:00

abstract：:We report a novel HIV-1 circulating recombinant form (CRF79_0107) from three epidemiologically unlinked patients through sexual contact in Shanxi province of China. This is the first second-generation circulating recombinant form identified in China. The breakpoint analysis of recombinants showed that CRF79_0107 was c...

journal_title：AIDS research and human retroviruses

authors： Li Y,Feng Y,Li F,Xue Z,Hu J,Xing H,Ruan Y,Shao Y

更新日期：2017-10-01 00:00:00

abstract：:We have evaluated the genetic diversity of HIV-1 strains infecting injecting drug users (IDUs) in Lisbon, Portugal. Heteroduplex mobility assay and/or phylogenetic analysis revealed that env (C2V3C3 or gp41) subtype B is present in 63.7% of the 135 viral samples studied, followed by subtypes G (23.7%), A (6.7%), F (5....

journal_title：AIDS research and human retroviruses

authors： Esteves A,Parreira R,Piedade J,Venenno T,Franco M,Germano de Sousa J,Patrício L,Brum P,Costa A,Canas-Ferreira WF

更新日期：2003-06-01 00:00:00

abstract：:The Brazilian AIDS epidemic is characterized by significant geographic contrasts: a reduction in incidence and mortality in the epicenter (southeast) and an increase in the northeast. HIV-1-transmitted drug resistance (TDR) and genetic diversity were investigated among 106 antiretroviral (ARV)-naive patients from Mara...

journal_title：AIDS research and human retroviruses

authors： Moura ME,Reis MN,Lima YA,Eulálio KD,Cardoso LP,Stefani MM

更新日期：2015-02-01 00:00:00