Abstract:
:Specific binding of [3H]-imipramine in the rat suprachiasmatic nuclei, occipital cortex and caudate putamen underwent significant and replicable changes throughout 24 hr under a light-dark cycle or under constant conditions. Daily variations were also found in the medial and dorsal raphe nuclei and the lateral hypothalamus. Methamphetamine, a psychoactive drug with marked effect on circadian rhythms in physiological and hormonal parameters and adrenergic receptors, did not have any significant effect on imipramine binding rhythms in eight discrete brain regions. Thus a drug known to reduce serotoninergic neurotransmission did not change characteristics of the modulatory binding site related to serotonin uptake.
journal_name
Chronobiol Intjournal_title
Chronobiology internationalauthors
Kraeuchi K,Wirz-Justice A,Morimasa T,Suetterlin-Willener R,Feer Hdoi
10.3109/07420528609066357subject
Has Abstractpub_date
1986-01-01 00:00:00pages
127-33issue
2eissn
0742-0528issn
1525-6073journal_volume
3pub_type
杂志文章abstract::The objectives of the study were to investigate the associations between night work and disability pension (DP) due to all causes, cardiovascular (CVD), mental, and other diagnoses, adjusting for familial confounding. The material of the study included comprehensive survey data on 27 165 Swedish twins born in 1935-195...
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abstract::Background: Numerous clinical studies have evaluated valsartan and found more efficacious control of blood pressure (BP) variability when administered before sleep. The treatment leads to improved outcomes when compared to administration upon awakening. The mechanism underlying this etiology is not fully understood. T...
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journal_title:Chronobiology international
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journal_title:Chronobiology international
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journal_title:Chronobiology international
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journal_title:Chronobiology international
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