Erythropoietin Induces an Epithelial to Mesenchymal Transition-Like Process in Mammary Epithelial Cells MCF10A.

abstract：:Emerging evidence indicates that some altered patterns of methylation that occur in breast tumors may also be found in breast tissue of healthy women in relation to the breast cancer (BC) risk factors. Progesterone receptor (PR) isoform α is a crucial regulator of breast hormone responsiveness and its hypermethylation...

journal_title：Journal of cellular biochemistry

authors： Daraei A,Izadi P,Khorasani G,Nafissi N,Naghizadeh MM,Younosi N,Meysamie A,Mansoori Y,Nariman-Saleh-Fam Z,Bastami M,Saadatian Z,Zendehbad Z,Tavakkoly-Bazzaz J

更新日期：2019-08-01 00:00:00

abstract：:Allele-specific transcription is a characteristic feature of imprinted genes. Many imprinted genes are also transcribed in a tissue- or cell type-specific manner. Overlapping epigenetic signals must, therefore, modulate allele-specific and tissue-specific expression at imprinted loci. In addition, long-range interacti...

journal_title：Journal of cellular biochemistry

authors： Hanel ML,Lau JC,Paradis I,Drouin R,Wevrick R

更新日期：2005-04-01 00:00:00

abstract：:Vacuolar H+ -ATPases (V-ATPases) are ubiquitous multisubunit proton pumps responsible for organellar pH maintenance. Mutations in the a3 subunit of V-ATPases cause autosomal recessive osteopetrosis, a rare disease due to impaired bone resorption. Patients with osteopetrosis also display dental anomalies, such as ename...

journal_title：Journal of cellular biochemistry

authors： Johnson L,Ganss B,Wang A,Zirngibl RA,Johnson DE,Owen C,Bradley G,Voronov I

更新日期：2017-10-01 00:00:00

abstract：:Estrogen and androgen are both critical for the maintenance of bone, but the target cells, mechanisms, and responses could be sex-specific. To compare sex-specific actions of estrogen and androgen on osteoclasts, human peripheral blood mononuclear precursor cells from adult Caucasian males (n = 3) and females (n = 3) ...

journal_title：Journal of cellular biochemistry

authors： Wang J,Stern PH

更新日期：2011-12-01 00:00:00

abstract：:We have partially purified and characterized an 87 kDa gelatinase activity expressed in later stage sea urchin embryos. Cleavage activity was specific for gelatin and no cleavage of sea urchin peristome type I collagen, bovine serum albumin or casein was detected. Magnesium and Zn2+ inhibited the gelatinase and Ca2+ p...

journal_title：Journal of cellular biochemistry

authors： Robinson JJ

更新日期：1997-09-01 00:00:00

abstract：:We previously suggested that keratinocyte releasable factors might modulate the wound healing process by regulating the expression of key extracellular matrix components such as collagenase (matrix metalloproteinase-1) and type I collagen in fibroblasts. The first one, we called it keratinocyte-derived anti-fibrogenic...

journal_title：Journal of cellular biochemistry

authors： Chavez-Muñoz C,Hartwell R,Jalili RB,Jafarnejad SM,Lai A,Nabai L,Ghaffari A,Hojabrpour P,Kanaan N,Duronio V,Guns E,Cherkasov A,Ghahary A

更新日期：2012-08-01 00:00:00

abstract：:This study aimed to identify differential circular RNA (circRNA) in the plasma exosomes of patients with lung adenocarcinoma (LUAD) using high-throughput sequencing. First, exosomes were isolated using an exosome isolation kit and confirmed by Western blotting, transmission electron microscopy, and NanoSight Assay. Su...

journal_title：Journal of cellular biochemistry

authors： Chen F,Huang C,Wu Q,Jiang L,Chen S,Chen L

更新日期：2020-03-01 00:00:00

abstract：:Decreased translation initiation adversely impacts protein synthesis and contributes to the myocardial dysfunction produced by sepsis. Therefore, the purpose of the present study was to identify sepsis-induced changes in signal transduction pathways known to regulate translation initiation in cardiac muscle and to det...

journal_title：Journal of cellular biochemistry

authors： Lang CH,Pruznak AM,Frost RA

更新日期：2005-02-01 00:00:00

abstract：:A homogeneous preparation of a urinary glycoprotein has been isolated from urine of patients with malignant melanoma and advanced adenocarcinomas of colon and lung. This molecule, Mr 30 kDa, is homologous to EDC1, a proteinase inhibitor antigenically related to plasma inter-alpha-trypsin inhibitor (IATI) originally is...

journal_title：Journal of cellular biochemistry

authors： Chawla RK,Lawson DH,Travis J

更新日期：1990-04-01 00:00:00

abstract：:Dynamic interactions between cellular membranes and the cytoskeleton are known to play major roles in many cellular responses to environmental cues. External signals resulting in proliferation, differentiation, polarization, and motility must be translated from chemical signals into changes of state, often involving t...

journal_title：Journal of cellular biochemistry

authors： Qi M,Liu Y,Freeman MR,Solomon KR

更新日期：2009-04-15 00:00:00

abstract：:Diclofenac is the most commonly used phenylacetic acid derivative non-steroidal anti-inflammatory drug (NSAID) that demonstrates significant analgesic, antipyretic, and anti-inflammatory effects. Several epidemiological studies have demonstrated anti-proliferative activity of NSAIDs and examined their apoptotic induct...

journal_title：Journal of cellular biochemistry

authors： Amanullah A,Upadhyay A,Chhangani D,Joshi V,Mishra R,Yamanaka K,Mishra A

更新日期：2017-05-01 00:00:00

abstract：:Oxoglutarate receptor 1 (OXGR1), as one of the intermediates in G protein-coupled receptors (GPCRs), plays a crucial role in the citric acid cycle receptor of α-ketoglutarate and metabolism. GPCR can control the cell proliferation by regulating the downstream signaling of G protein signaling pathways. The PI3K/AKT pat...

journal_title：Journal of cellular biochemistry

authors： Wang Q,Zhang Q,Zhang Y,Zhao X

更新日期：2019-04-01 00:00:00

abstract：:Hantavirus infections are now recognized to be a global problem. The hantaviruses include several genotypic variants of the virus with different distributions in varying geographical regions. The virus genotypes seem to segregate in association with certain manifestations specific for each syndrome. They primarily inc...

journal_title：Journal of cellular biochemistry

authors： Kalaiselvan S,Sankar S,Ramamurthy M,Ghosh AR,Nandagopal B,Sridharan G

更新日期：2017-05-01 00:00:00

abstract：:Previous studies demonstrated that, upon attaining confluence, a clone of the renal epithelial cell, LLC-PK1, expressed progressively binding sites for the lectin Dolichos biflorus agglutinin (DBA) at the apical cell surface. Activation of cAMP-dependent protein kinase enhanced surface expression dramatically. The goa...

journal_title：Journal of cellular biochemistry

authors： Amsler K

更新日期：1993-08-01 00:00:00

abstract：:Sexual differences on thyroxin 5'-deiodinase (5'-D) in the Harderian gland of Syrian hamsters were investigated. We compared the 24-h profile of 5'-D activity in male and female hamsters, observing a clear rhythm in males but not in females. Female values were always significantly higher than male ones. After pinealec...

journal_title：Journal of cellular biochemistry

authors： Rubio A,Menendez-Pelaez A,Buzzell GR,Vaughan MK,Vaughan GM,Reiter RJ

更新日期：1996-09-01 00:00:00

abstract：:We have examined the effect of calcium-dependent adhesion, mediated by N-cadherin, on cell signaling during chondrogenesis of multipotential embryonic mouse C3H10T1/2 cells. The activity of chondrogenic genes, type II collagen, aggrecan, and Sox9 were examined in monolayer (non-chondrogenic), and micromass (chondrogen...

journal_title：Journal of cellular biochemistry

authors： Modarresi R,Lafond T,Roman-Blas JA,Danielson KG,Tuan RS,Seghatoleslami MR

更新日期：2005-05-01 00:00:00

abstract：:Atherosclerosis and related cardiovascular diseases (CVD) represent one of the greatest threats to human health worldwide. The protection of vascular smooth muscle cells (VSMCs) from apoptosis in the plaque has become an important therapeutic target for atherosclerotic plaque stabilization. A significant association o...

journal_title：Journal of cellular biochemistry

authors： Ye Y,Fu F,Li X,Yang J,Liu H

更新日期：2016-01-01 00:00:00

abstract：:The non-receptor tyrosine kinase c-Src is activated in many human cancer types, and induces deregulation of cadherin-based cell-cell contacts and actin cytoskeleton. Because ezrin, a protein which cross-links the plasma membrane with the actin cytoskeleton, is often over-expressed in human cancers, and participates in...

journal_title：Journal of cellular biochemistry

authors： Elliott BE,Qiao H,Louvard D,Arpin M

更新日期：2004-05-01 00:00:00

abstract：:Chondrosarcoma (CHS) is a common malignant bone sarcoma and its occurrence increases with age. microRNAs (miRNAs) are a class of noncoding RNAs that participate in various biological processes and disease pathogenesis by targeting functional messenger RNA (mRNA). However, the modulation of miRNAs in CHS remains largel...

journal_title：Journal of cellular biochemistry

authors： Sui J,Liu Q,Zhang H,Kong Y

更新日期：2019-06-01 00:00:00

abstract：:Hyaluronan (HA) is a ubiquitous component of the extracellular matrix (ECM) and occurs transiently in both the cell nucleus and cytoplasm. It has been shown to promote cell motility, adhesion, and proliferation and thus it has an important role in such processes as morphogenesis, wound repair, inflammation, and metast...

journal_title：Journal of cellular biochemistry

authors： Entwistle J,Hall CL,Turley EA

更新日期：1996-06-15 00:00:00

abstract：:MicroRNAs (miRNAs) play an important role in the development and progression of non-small cell lung cancer (NSCLC). Recently, several studies have shown that miR-99a is downregulated in various cancers, which can affect tumor initiation and maintenance. Herein, we found that miR-99a was downregulated in NSCLC tissues ...

journal_title：Journal of cellular biochemistry

authors： Yu SH,Zhang CL,Dong FS,Zhang YM

更新日期：2015-02-01 00:00:00

abstract：:Embryonic stem cells (ESCs) are pluripotent, self-renewing cells. These cells can be used in applications such as cell therapy, drug development, disease modeling, and the study of cellular differentiation. Investigating the interplay of epigenetics, genetics, and gene expression in control of pluripotence and differe...

journal_title：Journal of cellular biochemistry

authors： Altun G,Loring JF,Laurent LC

更新日期：2010-01-01 00:00:00

abstract：:L-selectin and P-selectin glycoprotein ligand-1 (PSGL-1) are adhesion molecules that play critical roles in neutrophil rolling during inflammation and lymphocyte homing. On the other hand they also function as signaling receptors to induce cytoskeleton changes. The present study is to investigate the signaling kinases...

journal_title：Journal of cellular biochemistry

authors： Luo J,Xu T,Wang X,Ba X,Feng X,Deepak V,Zeng X

更新日期：2010-07-01 00:00:00

abstract：:Hepatocytes can be generated from embryonic stem cells (ESCs) using inducers such as chemical compounds and cytokines, but issues related to low differentiation efficiencies remain to be resolved. Recent work has shown that overexpression of lineage-specific transcription factors can directly cause cells phenotypic ch...

journal_title：Journal of cellular biochemistry

authors： Liu T,Zhang S,Xiang D,Wang Y

更新日期：2013-11-01 00:00:00

abstract：:The Wnt signaling pathway has recently been demonstrated to play an important role in bone cell function. In previous studies using DNA microarray analyses, we observed a change in some of the molecular components of the canonical Wnt pathway namely, frizzled-1 (FZD-1) and axil, in response to continuous parathyroid h...

journal_title：Journal of cellular biochemistry

authors： Kulkarni NH,Halladay DL,Miles RR,Gilbert LM,Frolik CA,Galvin RJ,Martin TJ,Gillespie MT,Onyia JE

更新日期：2005-08-15 00:00:00

abstract：:In this study, we have used the tumor promoter 12-o-tetradecanoylphorbol-13-acetate (TPA), as well as its biologically inactive analogue 4 alpha-phorbol 12,13-didecanoate (4 alpha-PDD), to investigate platelet protein phosphorylation and its possible correlation with platelet activation. Our data show that TPA, but no...

journal_title：Journal of cellular biochemistry

authors： Bourguignon LY,Field S,Bourguignon GJ

更新日期：1985-01-01 00:00:00

abstract：:Prion diseases are characterized by high accumulation of infectious prion proteins (PrP(Sc)) in brains. PrP(Sc) are propagated by the conversion of host-encoded cellular prion proteins (PrP(C)) which are essential for developing the disease but are heterogeneously expressed in brains. The disease can be transmitted to...

journal_title：Journal of cellular biochemistry

authors： Kuczius T,Kleinert J,Karch H,Sibrowski W,Kelsch R

更新日期：2011-03-01 00:00:00

abstract：:During embryonic development, the hematopoietic system is the first to generate terminally differentiated, functional cell types. The urgent necessity for the early formation of blood and blood vessels during embryogenesis means that the induction, expansion, and maturation of these systems must be rapidly and precise...

journal_title：Journal of cellular biochemistry

authors： Snyder A,Fraser ST,Baron MH

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:A critical feature for fibroblasts differentiation into myofibroblasts is the expression of alpha-smooth muscle actin (α-SMA) during the tissue injury and repair process. The epigenetic mechanism, DNA methylation, is involved in regulating α-SMA expression. It is not clear how methyl-CpG-binding protein 2 (M...

journal_title：Journal of cellular biochemistry

authors： Xiang Z,Zhou Q,Hu M,Sanders YY

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND AND AIM:Perillaldehyde (PAH), one of the major oil components in Perilla frutescens, is very critical to health maintenance, for a wide range of human chronic diseases, including cancers. AMP-activated protein kinase (AMPK) has been implicated in the activation of autophagy in distinct tissues. This study wa...

journal_title：Journal of cellular biochemistry

authors： Zhang Y,Liu S,Feng Q,Huang X,Wang X,Peng Y,Zhao Z,Liu Z

更新日期：2018-10-30 00:00:00