Sexual differences in 5'-deiodinase activity in the Harderian gland of Syrian hamsters and the effect of pinealectomy: regulation by androgens.

abstract：:Hamster embryo cells metabolize benzo(a)pyrene to derivatives that covalently modify the nuclear macromolecules including proteins. Not all proteins are modified to the same extent nor by the same metabolites. In particular, a protein of apparent molecular weight 32,000 is highly modified by derivatives of trans-9,10-...

journal_title：Journal of cellular biochemistry

authors： MacLeod MC,Mansfield BK,Selkirk JK

更新日期：1982-01-01 00:00:00

abstract：:Cyclin-dependent kinases (cdks) are the catalytic subunits of a large family of serine/threonine protein kinases whose best-characterized members are key regulators of eukaryotic cell cycle progression. They are activated by binding to regulatory subunits generally termed as cyclins. Cdk10 is a cdc2-related kinase tha...

journal_title：Journal of cellular biochemistry

authors： Bagella L,Giacinti C,Simone C,Giordano A

更新日期：2006-10-15 00:00:00

abstract：:Atherosclerosis and osteoporosis are the leading causes of mortality and morbidity in the World. Recent epidemiologic studies have demonstrated that these disease processes develop in parallel. Evidence indicates that hyperlipidemia plays a paradoxical role in both disease processes. However, the mechanism is not unde...

journal_title：Journal of cellular biochemistry

authors： Rajamannan NM

更新日期：2011-09-01 00:00:00

abstract：:Pre-eclampsia (PE) is a pregnancy disease that causes maternal death and threatens the health of newborns. Accumulating evidence has revealed the essential roles of long noncoding RNAs (lncRNAs) in the progression of PE. The present investigation determined lncRNA ZEB2 antisense RNA 1 (ZEB2-AS1) expression in PE and l...

journal_title：Journal of cellular biochemistry

authors： Gao Y,Guo X,Li Y,Sha W,She R

更新日期：2019-10-01 00:00:00

abstract：:Epithelial-to-mesenchymal transition (EMT) is a major process to regulate cell migration and invasion. Inhibition of epidermal growth factor receptor (EGFR)-mediated EMT by tyrosine kinase inhibitors (TKIs) is a strategy to prevent lung cancer invasion. However, drug resistance is emerged and accelerated invasion thro...

journal_title：Journal of cellular biochemistry

authors： Hsieh YS,Liao CH,Chen WS,Pai JT,Weng MS

更新日期：2017-12-01 00:00:00

abstract：:Platelet-derived growth factor (PDGF) has been implicated in smooth muscle cell (SMC) proliferation, a key event in the development of myointimal hyperplasia in vascular grafts. Recent evidence suggests that the PDGF receptor (PDGFR) tyrosine kinase inhibitor, imatinib, can prevent arterial proliferative diseases. Bec...

journal_title：Journal of cellular biochemistry

authors： Li L,Blumenthal DK,Masaki T,Terry CM,Cheung AK

更新日期：2006-12-15 00:00:00

abstract：:Previous studies from this and other laboratories have shown that variants of tumor cell lines can be selected for resistance to the lytic action of natural killer (NK) cells. One of these (K562-Clone I), when made resistant to the toxic effects of Concanavalin A (Con A-R1), regained its sensitivity to NK. Comparing t...

journal_title：Journal of cellular biochemistry

authors： Bernier LG,Sullivan AK

更新日期：1988-06-01 00:00:00

abstract：:The in vitro growth of primary erythroleukemia cells has been examined in the presence and absence of the hormone erythropoietin (EPO). Although these leukemic cells had previously been considered to be hormone-independent, addition of EPO was found to be essential for maximum growth in culture. Erythroid colonies tha...

journal_title：Journal of cellular biochemistry

authors： Hossain A,Kim JK,Hankins WD

更新日期：1986-01-01 00:00:00

abstract：:Pristimerin is a natural product derived from the Celastraceae and Hippocrateaceae families that were used as folk medicines for anti inflammation in ancient times. Although it has been shown that pristimerin induces apoptosis in breast cancer cells, the involved mechanism of action is unknown. The purpose of the curr...

journal_title：Journal of cellular biochemistry

authors： Yang H,Landis-Piwowar KR,Lu D,Yuan P,Li L,Reddy GP,Yuan X,Dou QP

更新日期：2008-01-01 00:00:00

abstract：:C. difficile toxin B is a potent cytotoxin known to disrupt the microfilaments of cultured cells. We have recently shown also increased phospholipase A2 activity in cells treated with toxin B. The activity was detected as a toxin-induced, dose-dependent release of 14C-arachidonic acid from prelabeled fibroblasts. Here...

journal_title：Journal of cellular biochemistry

authors： Shoshan MC,Florin I,Thelestam M

更新日期：1993-05-01 00:00:00

abstract：:Chronic lymphocytic leukemia (CLL), a severe problem all over the world and represents around 25% of all total leukemia cases, is generating the need for novel targets against CLL. Wnt signaling cascade regulates cell proliferation, differentiation, and cell death processes. Thus, any alteration of the Wnt signaling p...

journal_title：Journal of cellular biochemistry

authors： Bhattacharya M,Sharma AR,Sharma G,Patra BC,Lee SS,Chakraborty C

更新日期：2020-11-01 00:00:00

abstract：:NMR spectroscopy is able to detect subtle changes to the surface chemistry of cells. We have previously shown that high-resolution 1H NMR methods can identify tumor cells with the capacity to metastasize, and we now report that the long T2 relaxation value (500-800 ms) observed in metastatic rat mammary adenocarcinoma...

journal_title：Journal of cellular biochemistry

authors： Wright LC,May GL,Gregory P,Dyne M,Holmes KT,Williams PG,Mountford CE

更新日期：1988-05-01 00:00:00

abstract：:Adult human mesenchymal stem cells (MSCs) hold promise for an increasing list of therapeutic uses due to their ease of isolation, expansion, and multi-lineage differentiation potential. To maximize the clinical potential of MSCs, the underlying mechanisms by which MSC functionality is controlled must be understood. We...

journal_title：Journal of cellular biochemistry

authors： Pricola KL,Kuhn NZ,Haleem-Smith H,Song Y,Tuan RS

更新日期：2009-10-15 00:00:00

abstract：:Numerous studies have demonstrated the role of A3 adenosine receptor (A3AR) and signaling pathways in the multiple aspects of the tumor. However, there is a little study about the function of A3AR in the biological processes of cancer stem cells (CSCs). CSCs have a critical role in the maintenance and survival of brea...

journal_title：Journal of cellular biochemistry

authors： Jafari SM,Panjehpour M,Aghaei M,Joshaghani HR,Enderami SE

更新日期：2017-09-01 00:00:00

abstract：:Endometrial cancer is one of the most common gynecological malignant tumors. The roles of competing endogenous RNAs (ceRNAs) in this disease, however, remain unclear. In this study, we constructed a ceRNA network to reveal the core ceRNAs in endometrial cancer. Differentially expressed genes were summarized from The C...

journal_title：Journal of cellular biochemistry

authors： Wang Y,Huang T,Sun X,Wang Y

更新日期：2019-11-01 00:00:00

abstract：:Lumbar spinal canal stenosis (LSCS) is a degenerative disease observed by hypertrophy of the ligamentum flavum (LF) that cause compression of the lumbar neural content. Diabetes mellitus (DM) is a risk factor for the disease and we have shown previously that DM increases the fibrosis and elastic fiber loss in patients...

journal_title：Journal of cellular biochemistry

authors： Sidon E,Shemesh SS,Mor-Yossef Moldovan L,Wiesenfeld Y,Ohana N,Benayahu D

更新日期：2019-03-01 00:00:00

abstract：:The retinoblastoma is the most common intraocular malignant tumor in infants and children; it is one of the deadliest forms of cancer due to its limited sensitivity to chemotherapy and radiotherapy. In several cancers, chemoresistance is associated with autophagy induction. Non-coding RNAs, including long non-coding R...

journal_title：Journal of cellular biochemistry

authors： Huang J,Yang Y,Fang F,Liu K

更新日期：2018-05-01 00:00:00

abstract：:This study investigates the effect of nuclear factor erythroid 2-related factor 2-antioxidant response element (Nrf2-ARE) signaling pathway in vascular calcification (VC) via inducing Autophagy in renal vascular smooth muscle cells (VSMCs). VSMCs were assigned into six experimental groups: the normal control, high pho...

journal_title：Journal of cellular biochemistry

authors： Yao L,Wang J,Tian BY,Xu TH,Sheng ZT

更新日期：2017-12-01 00:00:00

abstract：:3-Acetyl-11-keto-β-boswellic acid (AKBA), a pentacyclic triterpenic acid present in gum resin of Boswellia serrata, has been found to possess antioxidant and neuroprotective properties. In this study, we aimed to examine protective properties of AKBA against glutamate-induced neuronal injury. To investigate the effect...

journal_title：Journal of cellular biochemistry

authors： Rajabian A,Sadeghnia HR,Hosseini A,Mousavi SH,Boroushaki MT

更新日期：2020-02-01 00:00:00

abstract：:This study aimed to address the insufficiency of traditional meta-analysis and provide improved guidelines for the clinical practice of osteosarcoma treatment. The heterogeneity of the fixed-effect model was calculated, and when necessary, a random-effect model was adopted. Furthermore, the direct and indirect evidenc...

journal_title：Journal of cellular biochemistry

authors： Zhang T,Zhang S,Yang F,Wang L,Zhu S,Qiu B,Li S,Deng Z

更新日期：2018-01-01 00:00:00

abstract：:Cervical cancer is a cancer arising from the cervix, and it is the fourth most common cause of death in women. Overexpression of fibronectin 1 (FN1) was observed in many tumors and associated with the survival and metastasis of cancer cells. However, the mechanism by which FN1 promotes cervical cancer cell viability, ...

journal_title：Journal of cellular biochemistry

authors： Zhou Y,Shu C,Huang Y

更新日期：2019-04-11 00:00:00

abstract：:Caveolae are plasma membrane subcompartments that have been implicated in signal transduction. In many cellular systems, caveolae are rich in signal transduction molecules such as G proteins and receptor-associated tyrosine kinases. An important structural component of the caveolae is caveolin. Recent evidence show th...

journal_title：Journal of cellular biochemistry

authors： De Luca A,Sargiacomo M,Puca A,Sgaramella G,De Paolis P,Frati G,Morisco C,Trimarco B,Volpe M,Condorelli G

更新日期：2000-04-01 00:00:00

abstract：:Anoikis is a form of programmed cell death induced by loss of contact from neighboring cells or from their extracellular matrix (ECM). Many tumorigenic cells are anoikis resistant, facilitating cancer progression and metastasis. Trastuzumab is a monoclonal antibody used for the treatment of breast and gastric cell can...

journal_title：Journal of cellular biochemistry

authors： Onyeisi JOS,Castanho de Almeida Pernambuco Filho P,de Araujo Lopes S,Nader HB,Lopes CC

更新日期：2019-08-01 00:00:00

abstract：:The intracellular (IC) face of the G-protein coupled receptors (GPCR), bradykinin (BK) B2 and angiotensin (AT) 1a, is similar in sequence homology and in size. Both receptors are known to link to Galphai and Galphaq but differ markedly in a number of physiologic actions, particularly with respect to their hemodynamic ...

journal_title：Journal of cellular biochemistry

authors： Yu J,Prado GN,Taylor L,Piserchio A,Gupta A,Mierke DF,Polgar P

更新日期：2002-01-01 00:00:00

abstract：:The adaptor protein-2 (AP-2) complex refers to a class of proteins that play an important role in cargo recognition and are involved in clathrin-mediated endocytosis of cargo proteins from the plasma membrane in animal cells. However, there have been few studies of AP-2 in insects. Here, we isolated an AP-2 gene from ...

journal_title：Journal of cellular biochemistry

authors： Wang X,Chao Y,Wang Y,Xu B,Wang C,Li H

更新日期：2019-10-01 00:00:00

abstract：:We previously suggested that keratinocyte releasable factors might modulate the wound healing process by regulating the expression of key extracellular matrix components such as collagenase (matrix metalloproteinase-1) and type I collagen in fibroblasts. The first one, we called it keratinocyte-derived anti-fibrogenic...

journal_title：Journal of cellular biochemistry

authors： Chavez-Muñoz C,Hartwell R,Jalili RB,Jafarnejad SM,Lai A,Nabai L,Ghaffari A,Hojabrpour P,Kanaan N,Duronio V,Guns E,Cherkasov A,Ghahary A

更新日期：2012-08-01 00:00:00

abstract：:The role of regucalcin, which is a regulatory protein in intracellular signaling pathway, in the regulation of glucose utilization and lipid production was investigated using the cloned rat hepatoma H4-II-E cells overexpressing regucalcin. The hepatoma cells (wild-type) and stable regucalcin/pCXN2-transfected cells (t...

journal_title：Journal of cellular biochemistry

authors： Nakashima C,Yamaguchi M

更新日期：2006-12-15 00:00:00

abstract：:Mouse BC3H1 myogenic cells and a bi-functional chemical cross linking reagent were utilized to investigate the polymerization of newly-synthesized vascular smooth muscle (alpha-actin) and non-muscle (beta- and gamma-actin) actin monomers into native F-actin filament structures during myogenesis. Two actin dimer specie...

journal_title：Journal of cellular biochemistry

authors： Qu G,Yan H,Strauch AR

更新日期：1997-12-15 00:00:00

abstract：:Neutrophils are essential for host defense and their programmed cell death and removal are critical for the optimal expression as well as for efficient resolution of inflammation. Delayed neutrophil apoptosis or impaired clearance of apoptotic neutrophils by macrophages contributes to the progression of chronic inflam...

journal_title：Journal of cellular biochemistry

authors： Filep JG,El Kebir D

更新日期：2009-12-01 00:00:00

abstract：:The perinucleolar compartment (PNC) is a distinct nuclear body that localizes to the nucleolar periphery. The PNC is predominantly found in cancer cells, and recent evidence suggests that PNC prevalence can be a pan-cancer marker for tumors of solid tissue origin. The PNC is a heritable structure enriched with newly t...

journal_title：Journal of cellular biochemistry

authors： Pollock C,Huang S

更新日期：2009-05-15 00:00:00