Abstract:
:We sought to describe the use and outcomes of small, medium and large premounted stents in patients with congenital heart disease, including incidence of and risk factors for re-intervention and development of in-stent stenosis. Premounted stents offer several advantages over traditional manually crimped bare-metal stents, especially in small patients. There are no data describing the medium-term effectiveness and outcomes of premounted stents in congenital heart disease. We performed a single-center retrospective review of all small, medium and large premounted stents implanted over an 8-year period. Premounted stents were implanted in 71 vessels within 59 patients with a 97 % success rate. Regardless of implantation site, premounted stent implantation resulted in significant improvements in vessel size and pressure gradient (p < 0.0001). Over a median follow-up duration of 3.1 years [interquartile range (IQR) 1.3-5.2], 25 patients (43 %) required re-intervention (18 catheter based, 3 surgical and 4 hybrid) at a median time of 1.4 years (IQR 0.9-3.0) from implant. Factors associated with re-intervention included age ≤1.9 years [hazard ratio (HR) 2.4, p = 0.03], weight ≤11.5 kg (HR 2.5, p = 0.03) and bare-metal premounted stents compared to covered premounted stents (HR 4.2, p = 0.001). In-stent stenosis was diagnosed in 42 % of premounted stents which underwent follow-up angiography. No identified characteristics were associated with in-stent stenosis, including "oversizing" the premounted stent. Small, medium and large premounted stents are effective in treating vascular stenosis in congenital heart disease. Frequent follow-up is required, especially in smaller patients with expected somatic growth, and to evaluate for in-stent stenosis which occurs in nearly half of premounted stents.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Boe BA,Zampi JD,Schumacher KR,Yu S,Armstrong AKdoi
10.1007/s00246-016-1466-8subject
Has Abstractpub_date
2016-12-01 00:00:00pages
1525-1533issue
8eissn
0172-0643issn
1432-1971pii
10.1007/s00246-016-1466-8journal_volume
37pub_type
杂志文章abstract::Combination of right and left ventricular outflow tracts obstruction is extremely rare. Neonates with combined aortic stenosis (AS) and pulmonary stenosis (PS) present in critical condition and required urgent treatment. The management approach is not well defined. We report five female neonates with combined AS and P...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-014-1000-9
更新日期:2014-12-01 00:00:00
abstract::Tricuspid valve malformation is a rare congenital heart disease. Prenatal diagnosis of Ebstein's anomaly (EA) and tricuspid valve dysplasia (TVD) is associated with high mortality. There are conflicting reports concerning accurate prognostication after diagnosis in utero. The aim of our study was to assess prognostic ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0355-z
更新日期:2012-12-01 00:00:00
abstract::A hemodynamically stable neonate with transposition of the great arteries suddenly went into cardiac arrest during preparation for transport to the operating room. Emergency echocardiography during cardiac massage detected coronary air embolism as the presumed cause of arrest. After about 15 minutes of resuscitation, ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-011-0088-4
更新日期:2011-12-01 00:00:00
abstract::All 91,823 children born in 1980 in Bohemia (population 6.314 million; area 52,478 square kilometers) were examined at least four times during infancy and at the age of three and four years. All children who died were autopsied and those with heart disease were selected. A total of 779 children (8.223/1000 live births...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/BF02083294
更新日期:1989-10-01 00:00:00
abstract::Anatomic evidence of intrauterine closure of ventricular septal defects (VSDs) has been reported rarely. Between 1985 and 1990, 112 autopsies were performed at the Mayo Clinic on third trimester stillborns and infants who died during the first week of life. There were 21 (19%) cases of congenital heart disease. VSD wa...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00797004
更新日期:1994-01-01 00:00:00
abstract::In August 2010, the Nit-Occlud® Lê (EUREVECO) became available for transcatheter coil occlusion of ventricular septal defects (VSDs). Retrospective European Registry for VSD Closure using the Nit-Occlud® Lê-VSD-Coil; analysis of the feasibility, results, safety and follow-up of VSD-closure over a 3-year period in 18 E...
journal_title:Pediatric cardiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00246-016-1502-8
更新日期:2017-02-01 00:00:00
abstract::We describe a patient diagnosed with a small atrial septal defect (3-4 mm) that had grown to 24 mm in diameter over a six-year period. Timing of transcatheter intervention may be affected by growth of the atrial septal defect and this reports the first case of an atrial septal defect outgrowing the possibility of tran...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-001-0068-1
更新日期:2002-09-01 00:00:00
abstract::Myocardial contractility and relaxation are highly dependent on calcium homeostasis. Immature myocardium, as in pediatric patients, is thought to be more dependent on extracellular calcium for optimal function. For this reason, intravenous calcium chloride infusions may improve myocardial function in the pediatric pat...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-015-1322-2
更新日期:2016-03-01 00:00:00
abstract::Increasingly the importance of how and why we make decisions in the medical arena has been questioned. Traditionally the aeronautical and business worlds have shed a light on this complex area of human decision-making. In this review we reflect on what we already know about the complexity of decision-making in additio...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-020-02295-1
更新日期:2020-03-01 00:00:00
abstract::Debilitating cardiomyocyte loss underlies the progression to heart failure. Although there have been significant advances in treatment, current therapies are intended to improve or preserve heart function rather than regenerate lost myocardium. A major hurdle in implementing a cell-based regenerative therapy is the in...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-009-9409-2
更新日期:2009-07-01 00:00:00
abstract::The hypothesis that mild recurrent aortic obstruction produces subtle changes in ambulatory blood pressure was investigated by performing 24-hour monitoring on 11 postoperative coarctation patients. Patients (age 16.1 +/- 2.7 years) were compared with normal controls (age 15.7 +/- 2.5 years, n = 15). Surgery (end-to-e...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00794187
更新日期:1995-07-01 00:00:00
abstract::Natriuretic peptides (NP) are released from the heart in response to pressure and volume overload. The biologic properties of NPs include counterregulation of the rennin-angiotensin-aldosterone pathway and a decrease in sympathetic tone resulting in diuresis, natriuresis, and vasodilation. Natriuretic peptides help to...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-010-9758-x
更新日期:2010-11-01 00:00:00
abstract::Pulmonary artery thrombosis in neonates occurs rarely. This report describes the case of a term infant with a pulmonary artery thrombosis presenting as persistent pulmonary hypertension of the newborn. The risk factors identified in the case included maternal diabetes and heterozygous factor V Leiden deficiency. The p...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-008-9349-2
更新日期:2009-05-01 00:00:00
abstract::Midodrine hydrochloride is a potent peripherally-acting alpha1 agonist that is well absorbed and rapidly metabolized to its active metabolite. It has been used for the treatment of refractory syncope but has the important side effect of supine hypertension. A 10-year-old boy with severe symptomatic orthostatic hypoten...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-006-0169-y
更新日期:2007-07-01 00:00:00
abstract::Aortic atresia and interrupted aortic arch is a rare cardiac combination. Review of the literature revealed nine cases. We present two patients with this combination and the additional finding of quadricuspid pulmonary valves, one of which was severely stenotic. In the latter patient, an aortopulmonary window was pres...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-004-0754-x
更新日期:2005-07-01 00:00:00
abstract::This review examines the mechanism of estrogen signaling in cardiomyocytes, with an emphasis on mechanisms that might be important in cardioprotection. It investigates estrogen signaling mediated by the nuclear estrogen receptors alpha and beta and the G-protein-coupled receptor (GPR 30/GPER). Estrogen signaling via n...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-010-9877-4
更新日期:2011-03-01 00:00:00
abstract::We studied the safety and efficacy of closing patent ductus arteriosus by Nit-Occlud coils via retrograde approach. This is a retrospective study of 46 attempts to close ducts by this method in two hospitals in Egypt and Iran. Ductus arteriosus was crossed by left or right Judkins or endhole catheters. The coil was de...
journal_title:Pediatric cardiology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1007/s00246-017-1589-6
更新日期:2017-04-01 00:00:00
abstract::Internationally, there have been isolated case reports published of children presenting with dilated cardiomyopathy (DCM) in the setting of undiagnosed rickets. Although there has been an increased prevalence of rickets in the United States, there has been only one documented case of associated DCM. At our institution...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-009-9444-z
更新日期:2009-08-01 00:00:00
abstract::Atrioventricular block has been described in association with cases of long QT syndrome and mortality is increased in this subgroup. We describe an infant with congenital QT prolongation and atrioventricular block with normal cardiac function, leading to the initial diagnosis of long QT syndrome. She subsequently deve...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-005-1114-1
更新日期:2006-01-01 00:00:00
abstract::Adult studies suggest a better functional outcome after aortic valve replacement with a pulmonary autograft compared with mechanical or homograft valves. Little is known about functional results after Ross surgery in growing children. This study reports formal exercise stress echocardiographic data from 26 pediatric R...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0218-7
更新日期:2012-06-01 00:00:00
abstract::We aimed to investigate the complications after epicardial pacemaker (PM) implantation in neonates and infants and their relationship with factors such as device size and patient size. Between May 2010 and July 2018, 55 patients under 1 year of age who underwent epicardial PM placement were retrospectively evaluated. ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-020-02306-1
更新日期:2020-04-01 00:00:00
abstract::The purpose of this study was to test the hypothesis that the incidence of crochetage on the R wave in inferior limb leads can be used for the diagnosis of pediatric secundum atrial septal defect (ASD). Two hundred fifty-six children with secundum ASD (case cohort) and 256 age- and gender-matched children without hear...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-018-1857-0
更新日期:2018-06-01 00:00:00
abstract::Severe atrioventricular valve (AVV) or semilunar valve (SLV) regurgitation in the setting of a single ventricle physiology may proceed to valve replacement if repair strategies fail. Outcome data for these children are limited. We present transplant-free survival of a case series of children with single ventricle phys...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-019-02234-9
更新日期:2020-01-01 00:00:00
abstract::This study was conducted to determine the efficacy of procainamide therapy for rapid rate control of postoperative junctional tachycardia (JT). Postoperative JT is one of the most difficult forms of tachycardia to manage. Reported success with a variety of treatments of JT in infants and children has been inconsistent...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002469910018
更新日期:2000-03-01 00:00:00
abstract::Intrathoracic ventricular aneurysms and diverticula can be differentiated by several criteria. Contractility is the only reliable parameter: aneurysms expand, whereas diverticula contract during ventricular systole. ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002460010264
更新日期:2001-09-01 00:00:00
abstract::The single right ventricle (RV) in hypoplastic left heart syndrome (HLHS) often develops systolic dysfunction with time and this affects prognosis. Mechanical dyssynchrony has been reported in HLHS but has not consistently correlated with systolic function or electrical dyssynchrony. The aims of this study were to ass...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-019-02091-6
更新日期:2019-06-01 00:00:00
abstract::The congenital anomaly of aortopulmonary window is rare. Its combination with interruption of the aortic arch has been previously recognized and reported in infants and children. Early and complete repair of such a congenital anomaly may prevent progression to cardiac failure and premature death. We describe the succe...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/BF02505097
更新日期:1996-03-01 00:00:00
abstract::With improvements in technology and surgical technique, pediatric cardiologists are challenging surgeons to close symptomatic ventricular septal defects (VSDs) in ever smaller patients. Although delaying surgery may facilitate operative repair, early intervention decreases the period of time these patients require the...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-007-9016-z
更新日期:2008-01-01 00:00:00
abstract::Patency of the ductus arteriosus (PDA) is a common finding in small premature infants. Recently pulsed-Doppler-cross sectional echocardiography (PD-CSE) has been successfully used in these patients. We report a case of a premature infant with an unusual PD-CSE pattern. ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02279882
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVES:The aim of this article is to examine the frequency, timing of formation of aneurysm of the ventricular membranous septum (AVMS), and prognosis in patients with a perimembranous ventricular septal defect (VSD). PATIENTS:One hundred forty-eight patients were diagnosed with a perimembranous VSD within 90 days...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-003-0572-6
更新日期:2004-07-01 00:00:00