Abstract:
:This review examines the mechanism of estrogen signaling in cardiomyocytes, with an emphasis on mechanisms that might be important in cardioprotection. It investigates estrogen signaling mediated by the nuclear estrogen receptors alpha and beta and the G-protein-coupled receptor (GPR 30/GPER). Estrogen signaling via nitric oxide and the PI3K pathway are discussed.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Murphy E,Lagranha C,Deschamps A,Kohr M,Nguyen T,Wong R,Sun J,Steenbergen Cdoi
10.1007/s00246-010-9877-4subject
Has Abstractpub_date
2011-03-01 00:00:00pages
354-9issue
3eissn
0172-0643issn
1432-1971journal_volume
32pub_type
杂志文章,评审abstract::Two children with acute symptomatic pericardial effusion had unusual echocardiographic findings. In each case, the pericardial effusion was hemorrhagic. Echocardiography displayed numerous linear bands coursing across the pericardial space. Recognition of this characteristic image may predict that an acute effusion is...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00817614
更新日期:1994-03-01 00:00:00
abstract::Increasingly the importance of how and why we make decisions in the medical arena has been questioned. Traditionally the aeronautical and business worlds have shed a light on this complex area of human decision-making. In this review we reflect on what we already know about the complexity of decision-making in additio...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-020-02295-1
更新日期:2020-03-01 00:00:00
abstract::There is often a diagnostic dilemma in pediatric patients presenting with depressed ventricular function, as myocarditis and dilated cardiomyopathy (DCM) of other etiologies can appear very similar. Accurate identification is critical to guide treatment and to provide families with the most accurate expectation of lon...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-018-1867-y
更新日期:2018-08-01 00:00:00
abstract::Noninvasive measurement of cardiac output (CO) and particularly stroke volume (SV) remain difficult but potentially valuable. These variables can be particularly challenging to measure in children with congenital heart disease (CHD). Impedance cardiography (IC) is a technique shown to be accurate in measuring SV in ad...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-016-1456-x
更新日期:2016-12-01 00:00:00
abstract::Extracardiac valved conduits are routinely employed in the correction of complex congenital heart lesions. Compression of a conduit and/or of the heart may present serious operative and postoperative complications. We believe its occurrence can be minimized and hemodynamic results improved by adhering to simple surgic...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02242263
更新日期:1983-07-01 00:00:00
abstract::Two cases of arrhythmogenic right ventricular dysplasia (ARVD) in siblings are reported. In the boy, 14 years old, the clinical history, ECG, echocardiography, and histopathological findings were consistent with ARVD. Premature ventricular contractions of left bundle branch block (LBBB) pattern were recorded but no ve...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02239576
更新日期:1990-04-01 00:00:00
abstract::This review discusses the historical aspects, current state of the art, and potential future advances in the areas of nomenclature and databases for congenital heart disease. Five areas will be reviewed: (1) common language = nomenclature, (2) mechanism of data collection (database or registry) with an established uni...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-006-1447-4
更新日期:2007-03-01 00:00:00
abstract::Intravenous immunoglobulin (IVIG) administered in the acute stage of Kawasaki disease (KD) is the standard therapy. Few reports describe nonresponders to initial treatment with IVIG in KD, which remains the most consistent risk factor for coronary artery lesions (CALs). This study aimed to investigate whether the seru...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-013-0724-2
更新日期:2013-01-01 00:00:00
abstract::The observation that endocardial fibroelastosis (EFE) can result from an immune response to maternal autoantibody deposition in the fetal myocardium raises the possibility that the fetal immune system may contribute to the pathogenesis of idiopathic EFE and dilated cardiomyopathy (DCM). This study sought to characteri...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-011-9980-1
更新日期:2011-12-01 00:00:00
abstract::Radiation exposure from pediatric cardiac catheterization may be substantial, although published estimates vary. We sought to report patient radiation dose across a range of diagnostic and interventional cases in a modern, high-volume pediatric catheterization laboratory. We retrospectively reviewed diagnostic and int...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-014-0869-7
更新日期:2014-06-01 00:00:00
abstract::Three infants, each with a clinical picture of dilated cardiomyopathy, underwent endomyocardial biopsy. Immunohistologic analysis revealed chronic myocarditis. In one infant, a postviral etiology of chronic myocarditis could be assessed on the basis of molecular techniques. Therapy with azathioprine and prednisone res...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002469900292
更新日期:1998-05-01 00:00:00
abstract::A 6-year-old girl with type 3 long QT syndrome was safely and successfully implanted with an implantable cardioverter-defibrillator (ICD) system. Prior to implantation, she had experienced uncontrollable life-threatening arrhythmia in spite of high-dose administration of mexiletine. An ICD coil lead for transvenous us...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-011-0065-y
更新日期:2011-10-01 00:00:00
abstract::Limited data exist on the impact of prenatal diagnosis and outcomes of fetal truncus arteriosus (TA). We sought to assess prenatal diagnostic accuracy and prenatal outcomes in fetuses with TA and compare postnatal outcomes in neonates with prenatally and postnatally diagnosed TA. Records were reviewed for patients dia...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-008-9328-7
更新日期:2009-04-01 00:00:00
abstract::We report a case of isolated ventricular inversion in a 42-year-old woman. This rare congenital cardiac anomaly was corrected by an intraatrial baffle procedure. She also underwent left-sided double-chamber endocardial pacemaker implantation for postoperative tachycardia bradycardia syndrome. ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-003-0583-3
更新日期:2004-09-01 00:00:00
abstract::In case of progressive cyanosis after modified Fontan procedure, intrahepatic shunting should be considered. Ligation of the hepatic vein is safe and effective in managing this condition, and it is important to ensure that the pressure difference between superior vena cava and the portal vein system remains minimal af...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002469900505
更新日期:1999-11-01 00:00:00
abstract::This case report describes a boy who had Kawasaki disease (KD) at age 12 months and had a recurrence one year later. The coronary arteries were normal following the initial episode; however, during the second episode he developed coronary aneurysms. Gallium-67 radionuclide imaging, echocardiography, and angiography we...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02310998
更新日期:1986-01-01 00:00:00
abstract::Modifications of the Fontan operation can afford excellent palliation for many patients with a variety of forms of single ventricle. In properly selected patients who are good candidates, early and late survival can be as high as 95-97%. However, mortality is considerably higher for patients with risk factors for poor...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-007-9003-4
更新日期:2007-11-01 00:00:00
abstract::In 810 schoolchildren (aged 5-14 years) the prevalence of a grade 1-3/6 vibratory innocent heart murmur (VIHM) is 41%. Restricted to a grade 2 or 3 VIHM, the prevalence is 14%, decreasing from 21% in the age-class 5-6 years to 8% for children 13-14 years of age. The prevalence of a grade 3 VIHM is 1%. Together with a ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00798120
更新日期:1994-11-01 00:00:00
abstract::We report our experience with asymptomatic valvar aortic stenosis diagnosed during infancy. During the period between November 1, 1986 and October 31, 1992 a total of 13 infants were diagnosed with asymptomatic aortic stenosis, 5 of whom showed rapid progression over the first 2 years of life. Two of these asymptomati...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002469900105
更新日期:1997-01-01 00:00:00
abstract::Severe atrioventricular valve (AVV) or semilunar valve (SLV) regurgitation in the setting of a single ventricle physiology may proceed to valve replacement if repair strategies fail. Outcome data for these children are limited. We present transplant-free survival of a case series of children with single ventricle phys...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-019-02234-9
更新日期:2020-01-01 00:00:00
abstract::The hybrid pathway for the management of patients with hypoplastic left heart syndrome was pioneered at our institution and is the preferred approach compared with the traditional Norwood pathway. Patients undergoing this surgery are generally <6 months of age, and pain management in this age group after surgery for c...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0233-8
更新日期:2012-10-01 00:00:00
abstract::The development of Leadless cardiac pacemakers avoids the inherent complications that may occur secondary to lead insertion. A large number of devices have been inserted in adult patients although data in pediatric patients are lacking. We aimed to assess our experience with the Leadless device in the pediatric popula...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-019-02277-y
更新日期:2020-04-01 00:00:00
abstract::The outcome in a series of 23 cases of tetralogy of Fallot diagnosed prenatally was compared to published figures for this condition when (a) identified postnatally or (b) treated surgically. There was a marked difference in the survival between these groups, with the highest mortality (75%) occurring when the diagnos...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00788220
更新日期:1992-01-01 00:00:00
abstract::Atrial flutter/fibrillation (AFL/AF) is a late complication in adults with repaired tetralogy of Fallot (TOF). Its effects on long-term prognosis are not fully understood. We evaluate the impact of AFL/AF in adults with repaired TOF on global mortality and unplanned hospitalizations during follow-up, and the predictor...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-019-02106-2
更新日期:2019-06-01 00:00:00
abstract::Conotruncal heart defect is a complex form of congenital heart disease and usually has a poor prognosis. Although previous studies have identified several missense variants in GATA4 gene that may cause CTD, it remains unclear whether they are involved in CTD pathogenesis because the study population was limited. The a...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-016-1542-0
更新日期:2017-03-01 00:00:00
abstract::The COVID-19 pandemic has had devastating direct consequences on the health of affected patients. It has also had a significant impact on the ability of unaffected children to be physically active. We evaluated the effect of deconditioning from social distancing and school shutdowns implemented during the COVID-19 pan...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-020-02513-w
更新日期:2021-01-04 00:00:00
abstract::A 2100-g neonate underwent a two-ventricular surgical repair of a right ventricle-dominant unbalanced atrioventricular septal defect associated with the heterotaxy syndrome and sinus node dysfunction. Postoperative congestive heart failure persisted despite bradycardia management by temporary ventricular pacing. Spect...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002469900446
更新日期:1999-05-01 00:00:00
abstract::Azygos continuation of inferior venacava (IVC) is well known in association with interrupted IVC. We report azygos connection of uninterrupted IVC in a young child with complex univentricular heart. This peculiar anatomy was made suitable for univentricular repair by combining percutaneous device closure of prehepatic...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-010-9802-x
更新日期:2011-01-01 00:00:00
abstract::Transcatheter closure of atrial septal defects (ASDs) has become a routine procedure in many countries of the world. It spares many patients cardiac surgery and has proven efficacy in long-term studies. Device improvements have resulted in a continuous reduction of complications and of residual shunt frequency. ASD cl...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-005-1011-7
更新日期:2005-05-01 00:00:00
abstract::Eighteen of 25 survivors of aortic valvotomy in infancy were reinvestigated by cross-sectional echocardiography a mean of 7.5 (2.3-13.4) years after surgery. They had been operated at a median age of 38 (5-330) days. At the follow-up examination the gradient across the aortic valve was 41 +/- 19 (15-85) mmHg and the e...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00788221
更新日期:1992-01-01 00:00:00