Abstract：
OBJECTIVES:To assess and compare the prevalence of prescribing of potentially inappropriate medications (PIMs) identified using the Beers and STOPP criteria; and to determine the clinical variables related with the prescription of PIMs in older adults. METHODS:An observational study of 250 patients aged 65 years or older was conducted in a large teaching hospital. Beers (2012) and STOPP (2008) criteria were utilized to identify PIMs. Data on age, sex, admission and discharge dates, diagnoses, and medications prescribed were obtained from medical records. Multivariate logistic regression was used to determine patient variables related with the prescription of PIMs. KEY FINDINGS:Using Beers criteria, 375 PIMs were identified in 198 patients. 32% of these patients were prescribed one PIM, 20% were prescribed two PIMs, and 48% were prescribed more than two PIMs. Using STOPP criteria, 148 PIMs were identified in 120 patients. 41% of these patients were prescribed one PIM, 51% were prescribed two PIMs, and 8% were prescribed more than two PIMs. An association between PIM prescribing and polypharmacy was detected with both criteria. After adjusting for confounding variables, the prescription of Beers-identified PIMs was significantly associated with patients older than 80 (OR: 2.99; 95% CI: 1.13-7.89) and with length of hospital stay of more than 15days (OR: 2.78; 95% CI: 1.20-6.44). CONCLUSION:These two criteria showed that the prescription of PIMs is prevalent in hospitalized elderly patients. It may be beneficial to educate healthcare teams about these criteria to reduce the prescription of PIMs.
journal_name
Arch Gerontol Geriatrjournal_title
Archives of gerontology and geriatricsauthors
Arellano C,Saldivia G,Córdova P,Fernández P,Morales F,López M,Villa Ldoi
10.1016/j.archger.2016.08.001subject
Has Abstractpub_date
2016-11-01 00:00:00pages
139-44eissn
0167-4943issn
1872-6976pii
S0167-4943(16)30139-Xjournal_volume
67pub_type
杂志文章abstract：AIMS:Type 2 Diabetes Mellitus(DM) is a well-known risk factor for cognitive impairment. Recent evidences suggest that Dipeptidyl peptidase-4(DPP-4) inhibitors might have neuroprotective effects. Therefore, this study aimed to investigate vildagliptin, a DPP-4 inhibitor, effects on cognitive function in older patients w...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2020.104013
更新日期：2020-01-01 00:00:00
abstract：:In Asian families, where patriarchal family systems are common, living arrangements of older adults are characterized by residing with a married son. This study examines the synergic effects of intergenerational solidarity (emotional and instrumental support exchange and anticipated support) on depression of older adu...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2010.06.007
更新日期：2011-07-01 00:00:00
abstract：:Falls among the elderly is a major public health concern. There has been recent extensive research on the effects of Tai Chi in fall prevention among the elderly. As such, we undertook a systematic review to look for evidence on the effect of this intervention. There were seven randomized controlled trials, which met ...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章,评审
doi：10.1016/j.archger.2008.02.018
更新日期：2009-05-01 00:00:00
abstract：OBJECTIVES:Various healthcare interventions have been launched targeting the growing population of older people. The objective of this study was to investigate the of a case management intervention for frail old people (aged 65+ years) effects on healthcare utilization. MATERIALS AND METHODS:The study was conducted in...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.archger.2014.10.009
更新日期：2015-01-01 00:00:00
abstract：:Depression is a major public health burden among the aging population. While older adults prefer non-pharmacological treatment, few options for psychotherapy are available in primary care settings, which is where older adults tend to receive mental health services. Indicated prevention is a cost-effective, public heal...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章,评审
doi：10.1016/j.archger.2012.03.003
更新日期：2012-11-01 00:00:00
abstract：:One hundred and eight patients have been investigated clinically, by computer tomography and by measuring the reaction time (RT). Thirty six controls without histories of brain disease, normal psychiatric findings and the same mean age as the other groups, were compared with 37 stroke patients without and 35 stroke pa...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/0167-4943(85)90044-5
更新日期：1985-12-01 00:00:00
abstract：:We examined whether social role and self-rated health in an older population were predictors for 6-year total mortality among a non-disabled community-dwelling older population in Saku City, Nagano Prefecture, Japan, surveyed in 1992 and 1998. A total of 8090 men and women aged 65-99 years who reported no disability i...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2005.05.002
更新日期：2006-01-01 00:00:00
abstract：:This study investigates the implications of different levels of cognitive decline on functional status in frail older adults. Four cognitive trajectories, including two with catastrophic cognitive decline, were defined in a 3-year study. Participants with complete cognitive and functional status data at baseline, 12 a...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2007.09.007
更新日期：2009-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the feasibility and short- and long-term effects of two 10-wk structured ergometer-cycling programs among elderly in assisted-living residences. DESIGN, SETTING, AND PARTICIPANTS:Eight assisted-living residences (N=95; age=81.2±5.9years) were randomly assigned to one of three conditions: 1) ergom...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.archger.2017.01.010
更新日期：2017-01-01 00:00:00
abstract：:The purpose of this paper is to describe the development and initial piloting of a Functional Status Assessment of Seniors in Emergency Department (FSAS-ED). The methodology of development of the tool included (1) specifying the underlying construct based on the conceptual framework of the International Classification...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2008.01.009
更新日期：2009-03-01 00:00:00
abstract：:Achieving guideline-recommended blood pressure targets is difficult in older adults with hypertension. We completed a subgroup analysis of patients 65 years of age or older enrolled in PREVIEW, a prospective, multicenter, pharmacoepidemiological study of the determinants and outcomes of second-line antihypertensive tr...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2009.07.009
更新日期：2010-07-01 00:00:00
abstract：:The most important morphological aspects of the physiological changes of the liver with age are decreases in the numbers of hepatocytes and their mitochondria, coupled with increases in their volumes. The latter is considered to partially compensate for the decrease in numbers of hepatocytes and mitochondria, but lead...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/0167-4943(94)90035-3
更新日期：1994-09-01 00:00:00
abstract：:The objectives of this study were to describe the changes occurring in depressive symptomatology over a 10-year period among 75-year-old residents of Jyväskylä, Finland. It also addressed the question of whether the mood disturbances detected were a permanent phenomenon or whether they had a more episodic nature. In a...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2003.10.004
更新日期：2004-05-01 00:00:00
abstract：:Mild cognitive impairment (MCI) can be a stage of pre-dementia. There is no consensus about pharmacological treatment for this population, so it is important to structure non-pharmacological interventions for increasing their cognitive reserve. We intended to analyze the effects of non-pharmacological interventions in...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章,评审
doi：10.1016/j.archger.2011.02.014
更新日期：2012-01-01 00:00:00
abstract：:Changes in body composition, including a decrease in muscle and bone mass, accompany aging. Our aim was to assess the prevalence of sarcopenia and its association with osteoporosis in hip-fracture women. We performed a Dual-Energy X-Ray Absorptiometry (DXA) scan in 313 of 340 women, 20.9 ± 6.5 (mean ± S.D.) days after...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2010.02.002
更新日期：2011-01-01 00:00:00
abstract：:The objective of this study is to investigate the cross-cultural relationship between depressive state and subjective economic status, as well as subjective quality of life (QOL) and activities of daily living (ADL) among elderly people in communities in Japan, Taiwan, and Korea. We studied 595 subjects aged 65 years ...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2014.11.003
更新日期：2015-03-01 00:00:00
abstract：:Insomnia is a significant problem that may jeopardize elderly residents' quality of life in long-term care settings. However, there are only a few studies dealing with sleeping disturbances among nursing home residents. The goal of this study was to determine the prevalence of insomnia and its associated factors in nu...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2005.06.008
更新日期：2006-01-01 00:00:00
abstract：:The epidemiologic data on smoking in association with Parkinson disease (PD) is puzzling. A lower incidence of smoking-related malignancies, especially lung cancer, has been reported by several studies in the patients with PD. In this study, we investigated polymorphic variations in the vascular endothelial growth fac...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2008.02.007
更新日期：2009-05-01 00:00:00
abstract：:Brain transfer rate (BTR) and brain to plasma concentration ratio (BPCR) of radiolabelled human serum albumin injected intravenously were calculated to evaluate the brain transfer of serum albumin in the cerebral cortex, the right hemi-brain and the olfactory bulb of senescence accelerated prone mice (SAMP8) and senes...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/s0167-4943(97)00022-8
更新日期：1997-11-01 00:00:00
abstract：:The concept of selective survival to advanced ages is introduced and discussed in relation to the black/white mortality "crossover" in the United States. Crossover refers to the phenomenon wherein black mortality rates become lower than white mortality rates after approximately age 75. This reversal of mortality rates...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章,评审
doi：10.1016/0167-4943(84)90022-0
更新日期：1984-10-01 00:00:00
abstract：:This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2015.01.012
更新日期：2015-01-31 00:00:00
abstract：:Two hundred and fifty-six carers of elderly people aged 70 and over were questioned on their attitudes towards their caring role and their preferences for their own future care. Despite the fact that most were providing assistance at high personal cost, most cares were highly committed to their caring role. However, t...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/0167-4943(92)90050-e
更新日期：1992-03-01 00:00:00
abstract：:Nutritional status and functional ability are mutually dependent especially in the elderly. This study examined the functional status-predictive ability of the MNA in a cross-sectional study. We analyzed the dataset of the "Survey of Health and Living Status of the Elderly in Taiwan" (SHLSET). Subjects were 2948≥65 ye...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2011.12.006
更新日期：2012-05-01 00:00:00
abstract：:There has been an extraordinary reversal in the perceived merits of sheltered housing. Once held up as the unquestioned solution to the housing needs of elderly people, it has now fallen under a cloud which has been referred to as a 'crisis of confidence'. This paper reassesses the contribution of research to the deba...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/0167-4943(91)90003-9
更新日期：1991-01-01 00:00:00
abstract：:In the period July 1991-December 1994, 120 consecutive patients underwent percutaneous transluminal coronary angioplasty (PTCA); 79% were males (mean age 70.0 +/- 5.4 years) and 21% females (mean age: 71.0 +/- 6.8 years). Patients have been divided into two groups: (i) Group A (67 patients), undergone PTCA with prolon...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/0167-4943(96)86935-4
更新日期：1996-01-01 00:00:00
abstract：:Using data from the Chinese Longitudinal Health Longevity Survey of 2005, 2008 and 2011, the authors compared the difference in the disability trajectory (DT) of survivor, decedent and dropped-out survey respondents and examined gender differences in DT using a group-based trajectory model, gender differences in the i...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2017.10.015
更新日期：2018-01-01 00:00:00
abstract：:This random double-blind trial compares psychological well-being and perceived quality of life in 60 subjects (18 M, 42 F), mean age 61 years, with age-associated memory impairment (AAMI), who were administered a standardised ginseng-containing vitamin complex or placebo for 9 months. We evaluated psychological well-b...
journal_title：Archives of gerontology and geriatrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0167-4943(95)00659-9
更新日期：1995-11-01 00:00:00
abstract：:The objective of this study was to further test the hypothesis that aging in the housefly is associated with increased oxidative stress. Age-related changes in the concentration of glutathione, NAD and NADP, which undergo oxidation-reduction reactions, and of H2O2, a potent cellular oxidant, were examined in the homog...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/0167-4943(87)90001-x
更新日期：1987-07-01 00:00:00
abstract：:The personal and societal impact of age-related cognitive decline supports the development of effective interventions. While some strategies, such as cognitive training, exercise or socio-intellectual engagement, appear beneficial, few studies have examined the association between personality and intervention efficacy...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2019.103992
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Home care agencies (HCAs) provide caregivers, who perform an important role in maintaining the health and well-being of older adults. However, during the COVID-19 pandemic, paid caregivers had the potential to inadvertently spread COVID-19. We sought to characterize the effects of COVID-19 on ...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2020.104214
更新日期：2020-07-30 00:00:00
