Abstract：
:Prostate Cancer (PCa) remains an exception among solid cancers since organ-sparing procedures are not considered as a standard option. Despite most men harbour low to intermediate risk disease at diagnosis, the vast majority are advised towards radical treatment. We performed a literature review to highlight and discuss why focal therapy (FT) would represent a feasible and attractive option in appropriately selected men. The rationale supporting this strategy relies in epidemiological, pathological, molecular and clinical findings. These include the shift towards the diagnosis of less aggressive and unifocal PCas, the presence of an identifiable index lesion which drives the natural history of the disease together with the absence of significant disease elsewhere in the gland in many patients. New diagnostic tools, especially multiparametric MRI, allow the detection of the index lesion with good accuracy and high reliability. FT might provide acceptable disease control and at the same time substantially reduce treatment related side-effects in those men who are eligible for such strategy. To allow its adoption as a standard of care, future studies need to address current limitations such as the lack of direct comparative research against standard treatment, as well as long-term disease-control outcomes.
journal_name
Arch Esp Uroljournal_title
Archivos espanoles de urologiaauthors
Marra G,Gontero P,Valerio Msubject
Has Abstractpub_date
2016-07-01 00:00:00pages
271-80issue
6eissn
0004-0614issn
1576-8260journal_volume
69pub_type
杂志文章,评审abstract：OBJECTIVE:The artificial sphincter has been utilized for urinary incontinence due to intrinsic sphincteric insufficiency, with good fixation of the urethra and a maximum urethral closing pressure of 20-30 cms H2O, or after failed attempts at correction using other techniques. This procedure is difficult to perform sinc...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1999-10-01 00:00:00
abstract：OBJECTIVE:Renal cell carcinoma is constantly associated with calcification, but ossification is extremely scarce. METHOD: We retrospectively analyzed two cases with clear cell renal cell carcinoma with osseous metaplasia. RESULTS: We criticized the oldest case of woman whose a 32x31mm irregular renal mass with calcific...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVE:To present the results of a retrospective study on laparoscopic varicocelectomy, with special reference to the changes in the operating time observed throughout the training period. METHODS:We have reviewed the laparoscopic varicocelectomy procedures performed from 1987 to 1997. The operating times were grap...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
abstract：:Patient reported outcome measures (PROMs) are essential to fully understand the impact of diseases and the effectiveness of treatment from a patient's perspective. Generic and disease-specific tools have been used to assess the impact of nephrolithiasis on patients' quality of life (QoL), as well as the impact of vari...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2021-01-01 00:00:00
abstract：:We report on a patient with a long history of rheumatoid arthritis who consulted for intense hematuria that was initially ascribed to carcinoma of the bladder. Subsequent patient evaluation, however, disclosed amyloidosis of the urinary bladder. The literature on amyloidosis of the urinary tract is reviewed. A detaile...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：:Hypogonadism may affect as much as 70% of the patients with chronic renal failure (CRF) in comparison with general population. Physiopathologically, it is a hypergonadotropic hypogonadism, with alterations in the pulsatile production of GnRH, FSH, LH and testicular testosterone, that is a general disorder of the hypot...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVES:Ultrasound guided prostate biopsy is the most effective test for prostate cancer diagnosis, but its sensitivity is not higher than 80% so that biopsy repetition must be considered in patients with persistent diagnostic doubts after a previous negative one. However, the majority will be negative as it happene...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2002-12-01 00:00:00
abstract：:Accepted methods for the treatment of localized prostatic cancer are radiotherapy and radical surgery. Results of different authors and analysis of survival curves suggest a higher cure rate with surgery, although there are no prospective randomized studies that demonstrate it. Patients treated with radical prostatect...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：1994-06-01 00:00:00
abstract：:Fifteen patients with infiltrating bladder carcinoma underwent partial cystectomy and cystoplasty with lyophilized human dura at our hospital from 1983 to 1988. The 5-year survival rate was 75% for stage B1, 60% for B2, 40% for C and 0% for D1. There were no intra- or post-operative deaths and the post-operative compl...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1990-07-01 00:00:00
abstract：OBJECTIVE:To report two rare cases of persistent müllerian duct syndrome. METHODS/RESULTS:Two patients with normal chromosome studies (46, XY) are presented. The radiological evaluation showed structures compatible with those of the müllerian duct. These structures were completely excised with excellent results. The h...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：1999-06-01 00:00:00
abstract：OBJECTIVES:The renal graft rupture (RGR) was first described in 1968; it is a severe situation, generally appearing in the immediate post-operative period. OBJECTIVES:To retrospectively analyze the incidence of renal graft rupture in the population of patients who underwent kidney transplant in the Renal Transplant De...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：10.4321/s0004-06142006000500005
更新日期：2006-06-01 00:00:00
abstract：OBJECTIVES:Metastatic prostate cancer is a very heterogeneous disease with several treatment options. In some cases of oligometastatic disease, local treatment of the primary tumor complemented by metastasis directed therapy seems to improve oncological results. The objectives of this study are to define and understand...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2018-03-01 00:00:00
abstract：:The present study was conducted to determine the reversibility of the seminal alterations following experimental unilateral cryptorchidism in relation to the time orchiopexy is performed. Two groups of 45 Wistar rats were subjected to mechanical unilateral cryptorchidism followed by prepubertal, early and late orchiop...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1994-04-01 00:00:00
abstract：OBJECTIVES:To report the principles of penile resculpturing of different deformities caused by M. Peyronie: restoration of penile length, girth and shape with or without penile prosthesis implantation. METHODS:In the period between February 2007 and March 2009, we performed grafting surgery for M. Peyronie in 98 patie...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2010-11-01 00:00:00
abstract：OBJECTIVES:Background. Nephron-sparing surgery (NSS)ensures excellent oncological and functional outcomes in treating small renal masses. Laparo- Endoscopic-Single-Site Surgery (LESS)is one of the major advances in the evolution of minimally invasive surgery. METHODS:A prospective evaluation of patients underwent LESS...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2012-04-01 00:00:00
abstract：:Herein we describe a case of vesical bilharziasis in a Spanish patient who became infected during a trip to an endemic area. The characteristic features of the disease and particularly its relationship to squamous type bladder tumors are discussed with a special focus on treatment with Praziquantel. ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：:To perform the adequate treatment of upper urinary tract lesions it is very important to have an exact diagnosis. When the suspicion of an upper tract urothelial tumor is established the initial evaluation is carried out by imaging diagnostic tests (intravenous urography, pyelography, and others). The association of r...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2004-04-01 00:00:00
abstract：:Radical cystectomy with extended pelvic lymphadenectomy remains the treatment of choice for muscle invasive bladder cancer and non-metastatic chorion-invasive high grade tumors resistant to treatment with intravesical chemotherapy. During the last decade the procedure has been refined and we have acquired the skills n...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2011-04-01 00:00:00
abstract：:The author studied all of the 1361 male patients that had been hospitalized from December 1986 to September 1990 for chronic urinary retention to determine the incidence of urothelial tumor of the bladder. Sixty-nine (5.07%) were found to have primary urothelial carcinoma of the bladder. However, in another study grou...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：OBJECTIVE:To report an uncommon case of idiopathic calcinosis of the scrotum. METHODS/RESULTS:A case of idiopathic scrotal calcinosis in a 50-year-old male who presented with multiple hard masses in the scrotum is described. Cytological (fine needle aspiration) and histological (biopsy and resection) analyses of these...
journal_title：Archivos espanoles de urologia
pub_type： 历史文章,杂志文章
doi：
更新日期：1997-11-01 00:00:00
abstract：OBJECTIVES:We review the main issues on epididymis obstruction and its diagnosis, as well as therapeutic indications and surgical techniques for epididymovasostomy. METHODS:We describe the microsurgical end-to-side epididymovasostomy technique using double needle 10-0 sutures. RESULTS:Various techniques of epididymov...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2004-11-01 00:00:00
abstract：OBJECTIVE:To analyze if there is a learning curve to get to perform high quality ultrasound guided prostate biopsies that enable to effectively perform the diagnosis of prostate cancer, taking the pathological result of the samples into consideration. METHODS:We retrospectively reviewed data from 790 ultrasound-guided...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2015-07-01 00:00:00
abstract：:A patient with a tumor in the right pelvic ureter is described herein. Following diagnosis by ureteroscopy, the patient underwent TUR utilizing a ureteroresectoscope. No short- or long-term complications were observed. The scant number of cases in the literature and the advantages afforded by this technique (noninvasi...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1990-07-01 00:00:00
abstract：OBJECTIVES:To move towards a more standardized approach in clinical practice to manage patients with castration-resistant prostate cancer (CRPC) in Spain. METHODS:A panel of 18 Spanish experts in Urology with expertise managing CRPC followed a modified Delphi process with two rounds and a final face-to-face consensus ...
journal_title：Archivos espanoles de urologia
pub_type： 共识发展会议,杂志文章
doi：
更新日期：2017-11-01 00:00:00
abstract：:Oligometastatic prostate cancer (PCA) has increasingly been detected in the era of modern imaging studies such as choline-specific and prostate-specific membrane antigen (PSMA)-positron emission tomography and X-ray computed tomography (PET/CT). Recent evidence suggests that durable control is attainable with local tr...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2019-03-01 00:00:00
abstract：:Vesicoureteral reflux remains one of the most controversial subjects in paediatric urology. The flooding of publications on reflux makes the understanding of this anomaly and its treatments quite opaque. Evidence Based Medicine might be a helpful tool to clarify the various approaches of reflux reflected in 6.715 publ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：10.4321/s0004-06142008000200008
更新日期：2008-03-01 00:00:00
abstract：OBJECTIVES:After the death of Professor Francisco Romero Aguirre (Zaragoza 6/7/1918-6/28/2006) we want to make known his great teaching vocation, so that we covered his link with University from the start of his studies to his professorship as first professor in urology in the Spanish University (1961), and his work at...
journal_title：Archivos espanoles de urologia
pub_type： 传,历史文章,杂志文章
doi：
更新日期：2007-10-01 00:00:00
abstract：:The authors carried out detailed experiments on cats under anaesthesia, with electrical stimulation of the L7, S1, S2 and S3 ventral roots and of the vesical detrusor in order to study their contraction. They varied the frequency, intensity and duration parameters of the stimulation beats, using as contraction index, ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1980-07-01 00:00:00
abstract：OBJECTIVES:To perform a bibliographic review of the laparoscopic approach for radiofrequency ablation of small renal masses. METHODS:For this review we used the Medline database. We reviewed the clinical guidelines of the American Urological Association, the European Association of Urology and other institutions. RES...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,meta分析,评审
doi：
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVE:To describe the clinical and histopathological manifestations of a case of pseudoepitheliomatous, keratotic and micaceous balanitis and review the literature on this rare condition. METHODS:A case of pseudoepitheliomatous, keratotic and micaceous balanitis in a 63-year-old man is presented. The lesion appear...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
