Abstract：
:Individuals with trait anxiety are often considered to be predisposed to psychiatric disorders. However, there is great heterogeneity in the development of psychiatric disorders in this group of people and the nature of the trait anxiety is still unclear. So, we decided to explore the correlations of brain structure and brain activity with trait anxiety in normal individuals. Specifically, we investigated the correlations between trait anxiety and regional grey matter volume (rGMV) and regional BOLD, using the Amplitude of Low Frequency Fluctuations (ALFF) as an index in 382 university students. The results showed that the level of trait anxiety was negatively correlated with rGMV in the right middle occipital gyrus. This result indicates that individuals with high trait anxiety tend to have less image processing on conscious level. Furthermore, we found that trait anxiety was positively correlated with the ALFF in the bilateral superior frontal gyrus and the right supplementary motor area, and negatively correlated with the ALFF in the cerebellum and the thalamus. These results indicate that individuals with high trait anxiety may be more sensitive to relationships and sensory information. Overall, this study's findings suggest that individuals with high trait anxiety have attenuated image processing on the conscious level, and exhibit stronger induced sensibility and over-processing of relationships, which is a brain imaging precondition for psychiatric disorders.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Yin P,Zhang M,Hou X,Tan Y,Fu Y,Qiu Jdoi
10.1016/j.bbr.2016.06.036subject
Has Abstractpub_date
2016-10-01 00:00:00pages
355-61eissn
0166-4328issn
1872-7549pii
S0166-4328(16)30391-6journal_volume
312pub_type
杂志文章abstract：:It was previously shown [17] that visual movement sensitive neurons lacking selectivity in the anterior parts of the dorsal superior temporal sulcus (STP) of monkeys exhibited selective responses to externally moved objects and failed to respond to the sight of the animal's own limb movements. This paper describes a s...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(95)00193-x
更新日期：1996-04-01 00:00:00
abstract：:Diabetes mellitus is associated with disturbances of cognitive functioning. The aim of this study was to examine cognitive functioning in diabetic rats using the 'Can test', a novel spatial/object learning and memory task, without the use of aversive stimuli. Rats were trained to select a single rewarded can from seve...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(01)00186-3
更新日期：2001-08-01 00:00:00
abstract：:This study compared repeated treatment with methamphetamine (4.0 mg/kg, i.p.) plus scopolamine (0.5 mg/kg, i.p.) and methamphetamine alone in behavioral sensitization and drug conditioning with respect to a reciprocal balance between the dopaminergic and cholinergic systems. Repeated methamphetamine plus scopolamine t...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(96)00032-0
更新日期：1996-10-01 00:00:00
abstract：:During studies of response properties of single units in the posterior parietal cortex of 6 awake monkeys, 168 neurons were encountered (7.1% of examined units) which showed anticipatory types of activity. These neurons were found on either side of the intraparietal sulcus. In area 5, this expectation activity was exp...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(87)90055-6
更新日期：1987-06-01 00:00:00
abstract：:Environmental enrichment (EE) at early stages of neurodevelopment attenuates HI-induced behavioral, histological and cellular damage. However, the effects of EE exposure during gestational or early postnatal period and the possible influence of sexual dimorphism on EE protection are not fully understood. Present study...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2018.11.036
更新日期：2019-02-01 00:00:00
abstract：:Nicotine facilitates hippocampus-dependent contextual but not hippocampus-independent cued delay fear conditioning. To test if the effects of nicotine are specific to contextual fear conditioning or would extend to another hippocampus-dependent version of fear conditioning, we compared the effects of nicotine on cued ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2004.04.009
更新日期：2004-11-05 00:00:00
abstract：:We studied the impact of aging during sleep in the rat models of Alzheimer's (AD) and Parkinson's (PD) disease cholinergic neuropathology to determine the possible different and earlier onset of age-related sleep disorder during the neurodegenerative diseases vs. healthy aging. We used the bilateral nucleus basalis (N...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2015.12.046
更新日期：2016-03-15 00:00:00
abstract：:To assess the light-induced electrical activity of rodent retinal ganglion cells (RGCs) regenerating into a peripheral nerve (PN) graft we used non-invasive recording of electroretinographic responses to the contrast-reversal of sinusoidal gratings (p-ERG). On comparing the retinas that received a PN graft and retinas...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(00)00184-4
更新日期：2000-07-01 00:00:00
abstract：:The endogenous opioid system is involved in ethanol reinforcement. Ethanol-induced changes in opioidergic transmission have been extensively studied in adult organisms. However, the impact of ethanol exposure at low or moderate doses during early ontogeny has been barely explored. We investigated the effect of prenata...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2014.08.022
更新日期：2014-11-01 00:00:00
abstract：:The present experiment was designed to examine the effects of prenatal stress and gender in latent inhibition. Prenatal stress has been proposed as a risk factor both for depression and for schizophrenia, and both of these syndromes are associated with alterations in the functional state of the dopamine system. There ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2004.09.013
更新日期：2005-03-30 00:00:00
abstract：:Post-traumatic stress disorder (PTSD) is a chronic and disabling condition arising after exposure to a severe traumatic event, which affects approximately eight percent of the population. The underlying neurobiology of PTSD, however, has only been partially understood. The exploration of fear memory and its extinction...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2019.112342
更新日期：2020-02-03 00:00:00
abstract：:After bilateral removal of the occipital lobe rabbits were studied in an enriched environment. At first their behaviour was severely impaired. After eight weeks the animals had learned to avoid obstacles, climb up ramps and jump from tables. It was shown that this recovery was due to the use of remaining visual struct...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(85)90175-5
更新日期：1985-05-01 00:00:00
abstract：:In this study the relationship between 6-hydroxydopamine lesions of dopaminergic innervation of the lateral septum and schedule-induced polydipsia was examined. Animals with lesions were found to have a significant increase in water intake during a test involving an intermittent schedule of food delivery. Additional e...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(85)90012-9
更新日期：1985-01-01 00:00:00
abstract：:In the rat, prenatal exposure to diazepam (DZ) induces a permanent reduction in GABA/BZ receptor (R) function and behavioural abnormalities. Environmental modifications during early stages of life can influence brain development and induce neurobiological and behavioural changes throughout adulthood. Indeed, a subtle,...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2005.02.022
更新日期：2005-06-20 00:00:00
abstract：:Clinical research has identified developmental delay and physical malformations in children prenatally exposed to the antiepileptic drug (AED) valproic acid (VPA). However, the early signs of neurodevelopmental deficits, their evolution during postnatal development and growth, and the dose effects of VPA are not well ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2016.05.023
更新日期：2016-09-15 00:00:00
abstract：:Chronic restraint stress alters hippocampal-dependent spatial learning and memory in a sex-dependent manner, impairing spatial performance in male rats and leaving intact or facilitating performance in female rats. Moreover, these stress-induced spatial memory deficits improve following post-stress recovery in males. ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2014.12.051
更新日期：2015-04-01 00:00:00
abstract：:Aerobic training has a neuroprotective effect, reduces the risk of developing neurodegenerative diseases and facilitates functional recovery. The present study assesses the effect of aerobic training on cognitive functions, hippocampal BDNF/TrkB ligand receptor system expression and serum levels of BDNF and corticoste...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2019.111963
更新日期：2019-09-16 00:00:00
abstract：:Rivastigmine (RVT) is a reversible inhibitor of cholinesterase approved worldwide for the treatment of cognitive dysfunctions, especially in Alzheimer's disease. Most previous pre-clinical studies have examined the effects of RVT treatment in a wide variety of pathological research models. Nonetheless, the effects of ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2019.112077
更新日期：2019-12-30 00:00:00
abstract：:Monkeys with V4 lesions and unoperated controls were tested behaviourally for their perception of the colour categories red, green, blue and yellow. As expected, the monkeys with V4 lesions took longer to acquire the colour discriminations. However, the pattern of learning was the same in the two groups of animals. Bo...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(05)80327-4
更新日期：1992-11-30 00:00:00
abstract：:In order to outline the involvement of the hippocampus in behavior and memory functions the results of grafting experiments in the hippocampal formation are presented in addition to former lesion and stimulation studies. Grafts of fetal hippocampal tissue were found to induce short-term beneficial effects on learning ...
journal_title：Behavioural brain research
pub_type： 杂志文章,评审
doi：10.1016/0166-4328(94)00125-y
更新日期：1995-01-23 00:00:00
abstract：:The endocannabinoid system is capable of modulating multiple physiological brain functions including learning and memory. Moreover, there is evidence that the processes of acquisition and consolidation have distinct biological basis. We used the cannabinoid agonist WIN 55,212-2 (WIN-2) to investigate whether chronic C...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2019.112231
更新日期：2020-01-13 00:00:00
abstract：:Between April 2007 and December 2015, the Veterans Health Administration (VHA) screened one million combat veterans for traumatic brain injury (TBI), among 2.6 million deployed during operations Enduring Freedom, Iraqi Freedom and New Dawn (OEF/OIF/OND). Since 2007, among those reporting, screened and referred for def...
journal_title：Behavioural brain research
pub_type： 杂志文章,评审
doi：10.1016/j.bbr.2016.08.036
更新日期：2018-03-15 00:00:00
abstract：:Social defeat is an ethologically relevant stress inducing neuroadaptive changes in the mesocorticolimbic dopaminergic system. Three weeks after 10 days of daily defeat salient behaviors and in vivo dopamine (DA) neuron firing were evaluated in mice. Prior defeat induced social avoidance and hyperphagia and increased ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2010.11.050
更新日期：2011-03-17 00:00:00
abstract：:The aim of this study was to trace by molecular imaging techniques the neural substrates of attention deficit hyperactivity disorder (ADHD) using the spontaneously hypertensive rat (SHR) as animal model. Adult SHR and Wistar-Kyoto (WKY) controls were used throughout this study. In experiment 1, naive male SHR and WKY ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(97)00180-0
更新日期：1998-07-01 00:00:00
abstract：:In the present experiments, the anxiolytic action of Ucn 3 fragments were studied in an elevated plus maze in mice following icv administration in an attempt to identify the biologically active center of the molecule. Ucn 3, Ucn 3 (18-38), Ucn 3 (19-27), Ucn 3 (28-38), Ucn 3 (34-38), and Ucn 3 (36-38) but not Ucn 3 (3...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2011.03.047
更新日期：2011-09-23 00:00:00
abstract：:The current study was performed to assess the effects of inorganic mercury (mercuric chloride - HgCl(2)) on the development of offsprings from intoxicated-mother during pregnancy. In this respect, pregnant rats were chronically treated with HgCl(2) at 50 ppm (Hg50) and 100 ppm (Hg100) in drinking water. After parturit...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2012.06.005
更新日期：2012-09-01 00:00:00
abstract：BACKGROUND:The predominant view of chronic cocaine use maintains that it causes a broad range of cognitive deficits. However, concerns about the possibly deleterious impact of cocaine on cognitive functioning have yet to be thoroughly vetted. This review addresses the impact of cocaine use on such cognitive domains as ...
journal_title：Behavioural brain research
pub_type： 杂志文章,评审
doi：10.1016/j.bbr.2018.04.005
更新日期：2018-08-01 00:00:00
abstract：:Maternal care is the newborns' first experience of social interaction, which affects their development and social competence throughout life. For the first time, we investigated the involvement of the endocannabinoid system (ECS) in mother-infant interaction in mice. We found that blocking the dam's CB1 receptors (CB1...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2011.10.016
更新日期：2012-01-15 00:00:00
abstract：:Pit vipers use infrared-sensitive pit organs to accurately target homeothermic prey even in the absence of visual cues. It has been suggested that other vipers, including large ambush predators of the genus Bitis, also may use radiant infrared information for predatory targeting. We compared behavioral responses of pi...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2004.01.020
更新日期：2004-09-23 00:00:00
abstract：:Voluntary wheel running in rodents is associated with a number of adaptive behavioral and physiological effects including improved learning, reduction in stress-associated behaviors, neurogenesis, angiogenesis, increases in neurotrophic factors, and changes in several signaling molecules. Exercise has also been report...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2008.07.036
更新日期：2009-01-30 00:00:00
