Abstract：
:Social defeat is an ethologically relevant stress inducing neuroadaptive changes in the mesocorticolimbic dopaminergic system. Three weeks after 10 days of daily defeat salient behaviors and in vivo dopamine (DA) neuron firing were evaluated in mice. Prior defeat induced social avoidance and hyperphagia and increased ventral tegmental area (VTA) DA neuron bursting activity. These data extend previous studies and suggest that increased phasic DA neuron firing in the VTA could be considered amongst the features defining the lasting imprint of social defeat stress.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Razzoli M,Andreoli M,Michielin F,Quarta D,Sokal DMdoi
10.1016/j.bbr.2010.11.050subject
Has Abstractpub_date
2011-03-17 00:00:00pages
253-7issue
1eissn
0166-4328issn
1872-7549pii
S0166-4328(10)00775-8journal_volume
218pub_type
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