The study of nevi in children: Principles learned and implications for melanoma diagnosis.

Abstract:

:Melanocytic nevi are a strong phenotypic marker of cutaneous melanoma risk. Changes in nevi during childhood and adolescence make these prime periods for studying nevogenesis. Insights gained by the study of nevi in childhood have implications for melanoma detection in both adults and children. A more comprehensive understanding of the morphologic characteristics of nevi in different anatomic locations, in association with the patient's age and pigmentary phenotype may aid in the identification of melanomas. When monitoring melanocytic lesions over time, it is essential to differentiate normal from abnormal change. This review summarizes the rapidly expanding body of literature relevant to nevus phenotype, particularly in the context of our experience with the Study of Nevi in Children (SONIC) Project.

journal_name

J Am Acad Dermatol

authors

Scope A,Marchetti MA,Marghoob AA,Dusza SW,Geller AC,Satagopan JM,Weinstock MA,Berwick M,Halpern AC

doi

10.1016/j.jaad.2016.03.027

subject

Has Abstract

pub_date

2016-10-01 00:00:00

pages

813-823

issue

4

eissn

0190-9622

issn

1097-6787

pii

S0190-9622(16)30010-X

journal_volume

75

pub_type

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