Abstract：
:The aim of this study was to evaluate the shedding of Brucella abortus in the milk of cows vaccinated with a full dose of RB51 during lactation. Eighteen cows, nine previously vaccinated with S19 as calves and nine non-vaccinated, were immunized subcutaneously with 1.3×10(10)CFU of B. abortus RB51, 30-60days after parturition. Milk samples from all animals were collected daily until day 7, and at weekly interval for the next 9 weeks after vaccination. To evaluate the shedding of B. abortus, milk samples were submitted for culture and PCR. No B. abortus was isolated from any sample tested. Only one sample, collected on first day after vaccination from a cow previously vaccinated, was faintly positive in the PCR. In conclusion, the public health hazard associated with milk consumption from cows vaccinated with RB51 in post-partum is very low, despite vaccination with the full dose and regardless of previous S19 vaccination.
journal_name
Acta Tropjournal_title
Acta tropicaauthors
Miranda KL,Poester FP,Dorneles EM,Resende TM,Vaz AK,Ferraz SM,Lage APdoi
10.1016/j.actatropica.2016.04.012subject
Has Abstractpub_date
2016-08-01 00:00:00pages
58-61eissn
0001-706Xissn
1873-6254pii
S0001-706X(16)30215-7journal_volume
160pub_type
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