当前位置： SCI文献检索 > ACTA TROPICA期刊下所有文献 > Trypanosoma cruzi strains, Tulahuen 2 and Y, besides the difference in resistance to oxidative stress, display differential glucose-6-phosphate and 6-phosphogluconate dehydrogenases activities.

Trypanosoma cruzi strains, Tulahuen 2 and Y, besides the difference in resistance to oxidative stress, display differential glucose-6-phosphate and 6-phosphogluconate dehydrogenases activities.

Abstract：

:The drugs currently available for Chagas'disease treatment are unsatisfactory due to limited efficacy and toxic side effects, making the search for more specific pharmacological agents a priority. The components of the Trypanosoma cruzi trypanothione-dependent antioxidant system have been pointed out as potential chemotherapeutic targets for the development of more specific drugs. To work properly, this system must have a current supply of NADPH, provided by glucose-6-phosphate dehydrogenase (G6PD) and 6-phosphogluconate dehydrogenase (6PGD). Here, we compare two T. cruzi strains, Tulahuen 2 and Y, regarding growth rate, cytosolic tryparedoxin peroxidase (TcCPX) concentration and pentose phosphate pathway dehydrogenases activities. Tulahuen 2 cells show higher values as compared to the Y strain when the following parameters are compared: TcCPX concentration, resistance to H2O2, growth index and G6PD activity. Different patterns of G6PD and 6PGD activities were observed among strains along the growth curve and when cells were challenged with H2O2. These data reinforce the heterogeneity within T. cruzi populations and also the importance of G6PD in protecting the parasite against reactive oxygen species.

journal_name

Acta Trop

journal_title

Acta tropica

authors

Mielniczki-Pereira AA,Chiavegatto CM,López JA,Colli W,Alves MJ,Gadelha FR

doi

10.1016/j.actatropica.2006.12.001

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

54-60

issue

1

eissn

0001-706X

issn

1873-6254

pii

S0001-706X(06)00245-2

journal_volume

101

pub_type

杂志文章

相关文献

ACTA TROPICA文献大全
  • Studies on the effect of the anti-phagocytic agent cytochalasin B on Leishmania-macrophage interaction.

    abstract：:Mouse peritoneal exudate cells were cultured on coverslips in Eagle's Basal Essential Medium. The adhering cells were infected with promastigotes of three different species of Leishmania. After 8 h incubation, the macrophages were fixed and stained, and a total of one hundred cells were counted. The rates of infection...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：

    authors： Ardehali SM,Khoubyar K,Rezai HR

    更新日期：1979-03-01 00:00:00

  • Environmental factors underlying spatial patterns of sand flies (Diptera: Psychodidae) associated with leishmaniasis in southern Sinai, Egypt.

    abstract：:Although Leishmania major is endemic in parts of the Sinai of Egypt, the ecology and distribution of Leishmania sand fly vectors in southern Sinai has not been well characterized. Accordingly, additional sand fly samples were obtained at 41 sites in the southern Sinai region during 1996-1997, and analyzed to improve t...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/j.actatropica.2012.02.067

    authors： Kassem HA,Siri J,Kamal HA,Wilson ML

    更新日期：2012-07-01 00:00:00

  • Absence of the LiTat 1.3 (CATT antigen) gene in Trypanosoma brucei gambiense stocks from Cameroon.

    abstract：:Antibodies to the variable antigen type (VAT) designated LiTat 1.3 are common in sera from parasitologically confirmed patients with gambian sleeping sickness. For this reason, LiTat 1.3 has been considered a suitable antigen for detecting Trypanosoma brucei gambiense in the Card Agglutination Test for Trypanosomiasis...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/0001-706x(92)90054-2

    authors： Dukes P,Gibson WC,Gashumba JK,Hudson KM,Bromidge TJ,Kaukus A,Asonganyi T,Magnus E

    更新日期：1992-06-01 00:00:00

  • From parasitic disease control to global health: New orientation of the National Institute of Parasitic Diseases, China CDC.

    abstract：:As the only specialized institution for research and control of parasitic diseases at the national level in China for almost 70 years, the National Institute of Parasitic Diseases (NIPD) at the Chinese Center for Disease Control and Prevention (China CDC) has been instrumental in supporting the remarkable progress fro...

    journal_title：Acta tropica

    pub_type： 杂志文章,评审

    doi：10.1016/j.actatropica.2019.105219

    authors： Chen J,Ding W,Li Z,Zhou DD,Yang P,Wang RB,Zheng B,Sheng HF,Guan YY,Xiao N,Li SZ,Zhou XN

    更新日期：2020-01-01 00:00:00

  • Spatial distribution and molecular characterization of Anopheles nivipes and Anopheles philippinensis (Diptera: Culicidae) in north-east India.

    abstract：:Anopheles philippinensis-nivipes species of mosquitoes are considered secondary malaria vectors in the north-east India. However, difficulty in separating An. philippinensis and An. nivipes accurately on the basis of morphological identification, due to the overlapping female wing characters, has led to the paucity of...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/j.actatropica.2012.02.065

    authors： Sarma NP,Prakash A,Bhattacharyya DR,Kalita MC,Mohapatra PK,Singh S,Sarma DK,Mahanta J

    更新日期：2012-06-01 00:00:00

  • Preventive prospective of triclosan and triclosan-liposomal nanoparticles against experimental infection with a cystogenic ME49 strain of Toxoplasma gondii.

    abstract：:The preventative effect of triclosan (TS) and TS liposomal nanoparticles was studied on the early establishment of chronic infection with Toxoplasma gondii (T. gondii). Swiss albino mice were orally infected with 10 cysts of avirulent ME49 strain of T. gondii, and 2 weeks later they were orally treated with dual daily...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/j.actatropica.2014.09.020

    authors： El-Zawawy LA,El-Said D,Mossallam SF,Ramadan HS,Younis SS

    更新日期：2015-01-01 00:00:00

  • Advances in malaria genomics since MIM Arusha, 2002.

    abstract：:The promise of new interventions against malaria and other infectious diseases of global health importance derived from pathogen genomic sequence data may only be realized through the coordinated effort of genomic and post-genomics scientists, vaccine and drug developers along with lab- and field-based investigators. ...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/j.actatropica.2005.06.010

    authors： Carucci DJ

    更新日期：2005-09-01 00:00:00

  • First record of Leishmania braziliensis presence detected in bats, Mato Grosso do Sul, southwest Brazil.

    abstract：:Leishmaniasis, a zoonotic disease caused by parasites of the genus Leishmania, has expanded beyond its natural range and is becoming increasingly urban. Using PCR and PCR-RFLP, we detected Leishmania (Viannia) braziliensis in two bats (Chiroptera) in Mato Grosso do Sul, Brazil, an endemic area. This is the first recor...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/j.actatropica.2013.07.004

    authors： Shapiro JT,da Costa Lima Junior MS,Dorval ME,de Oliveira França A,Cepa Matos Mde F,Bordignon MO

    更新日期：2013-10-01 00:00:00

  • Severe malaria in Cameroonian children: correlation between plasma levels of three soluble inducible adhesion molecules and TNF-alpha.

    abstract：:Plasma levels of three soluble inducible adhesion molecules, namely: intercellular adhesion molecule-1 (sICAM-1), vascular cell adhesion molecule-1 (sVCAM-1) and endothelial leucocyte adhesion molecule-1 (sELAM-1) or sE-selectin and the pro-inflammatory cytokine, tumour necrosis factor-alpha (TNF-alpha) were measured ...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/j.actatropica.2007.02.011

    authors： Tchinda VH,Tadem AD,Tako EA,Tene G,Fogako J,Nyonglema P,Sama G,Zhou A,Leke RG

    更新日期：2007-04-01 00:00:00

  • Japanese encephalitis in Indonesia: An update on epidemiology and transmission ecology.

    abstract：:The Japanese Encephalitis (JE) virus circulation in Indonesia was first documented in Lombok in 1960, and the virus was first isolated in 1972 from Culex tritaeniorhynchus in Bekasi, West Java and Kapuk, West Jakarta. Since then, Indonesia has been recognized as an endemic country for JE transmission. Up to now, JE ca...

    journal_title：Acta tropica

    pub_type： 杂志文章,评审

    doi：10.1016/j.actatropica.2018.08.017

    authors： Garjito TA,Widiarti,Anggraeni YM,Alfiah S,Tunggul Satoto TB,Farchanny A,Samaan G,Afelt A,Manguin S,Frutos R,Aditama TY

    更新日期：2018-11-01 00:00:00

  • Viruses of parasites as actors in the parasite-host relationship: A "ménage à trois".

    abstract：:The complex parasite-host relationship involves multiple mechanisms. Moreover, parasites infected by viruses modify this relationship adding more complexity to the system that now comprises three partners. Viruses infecting parasites were described several decades ago. However, until recently little was known about th...

    journal_title：Acta tropica

    pub_type： 杂志文章,评审

    doi：10.1016/j.actatropica.2016.11.028

    authors： Gómez-Arreaza A,Haenni AL,Dunia I,Avilán L

    更新日期：2017-02-01 00:00:00

  • Phoenix dactylifera, mentha piperita and montanide™ ISA-201 as immunological adjuvants in a chicken model.

    abstract：:This study evaluated plant-based immune-adjuvants from crude extracts of Phoenix dactylifera and Mentha piperita as promising adjuvants for vaccines because of the limited side effects associated with plant extracts. In addition, Montanide™ ISA 201 previously used in vaccines in cattle. Eight different infectious cory...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/j.actatropica.2019.105281

    authors： Osman KM,Kamal OE,Deif HN,Ahmed MM

    更新日期：2020-02-01 00:00:00

  • Variable geographic distribution of Blastocystis subtypes and its potential implications.

    abstract：:Blastocystis is a common intestinal micro-eukaryote found in both humans and non-human hosts and known to be genetically very diverse. It has been divided into numerous subtypes (STs), nine of which have been identified in humans to date. Surveys of ST prevalence have started to emerge over the past few years but to d...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/j.actatropica.2012.12.011

    authors： Alfellani MA,Stensvold CR,Vidal-Lapiedra A,Onuoha ES,Fagbenro-Beyioku AF,Clark CG

    更新日期：2013-04-01 00:00:00

  • Sub-microscopic Plasmodium falciparum infections in matched peripheral, placental and umbilical cord blood samples from asymptomatic Congolese women at delivery.

    abstract：:In malaria-endemic areas, most pregnant women are susceptible to asymptomatic Plasmodium falciparum infections. We present here the results of a cross-sectional study conducted in Madibou, a southern district of Brazzaville in the Republic of Congo, between March 2014 and April 2015. The main aim was to characterize P...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/j.actatropica.2019.03.001

    authors： Mbouamboua Y,Koukouikila-Koussounda F,Ntoumi F,Adukpo S,Kombo M,Vouvoungui C,van Helden J,Kobawila SC

    更新日期：2019-05-01 00:00:00

  • Development of Trypanosoma cruzi in the vector in the absence of blood.

    abstract：:First stage nymphs of Triatoma infestans and Dipetalogaster maximus which had never fed after egg hatching, were allowed to ingest by artificial feeding a blood-free suspension of Trypanosoma cruzi trypomastigotes collected from experimentally infected mice. A high percentage of the vectors acquired a normal infection...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：

    authors： Alvarenga NJ,Brener Z

    更新日期：1978-12-01 00:00:00

  • Host use and seasonality of Culex (Melanoconion) iolambdis (Diptera: Culicidae) from eastern Florida, USA.

    abstract：:Culex (Melanoconion) iolambdis (Dyar, 1918) is a mosquito (Diptera: Culicidae) species found throughout much of tropical America, including southern Florida. Relatively few reports are available regarding the ecology of Cx. iolambdis, despite its widespread distribution and putative involvement in transmission of Vene...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/j.actatropica.2016.10.001

    authors： Blosser EM,Stenn T,Acevedo C,Burkett-Cadena ND

    更新日期：2016-12-01 00:00:00

  • Nectar protein content and attractiveness to Aedes aegypti and Culex pipiens in plants with nectar/insect associations.

    abstract：:We chose five easily propagated garden plants previously shown to be attractive to mosquitoes, ants or other insects and tested them for attractiveness to Culex pipiens and Aedes aegypti. Long term imbibition was tested by survival on each plant species. Both mosquito species survived best on Impatiens walleriana, the...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/j.actatropica.2015.03.010

    authors： Chen Z,Kearney CM

    更新日期：2015-06-01 00:00:00

  • Comparative efficacy of two rounds of indoor residual spraying of DDT 75% @ 1g/m2 with that of DDT 50% @ 1g/m2 against the malaria vectors in India.

    abstract：:While, dichlorodiphenyl-trichloroethane (DDT) water dispersible powder (WDP) 75% is considered as the high performance long lasting formulation for indoor residual spraying (IRS), no information is available regarding the comparative epidemiological effectiveness of the two DDT formulations when used for IRS in Indian...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/j.actatropica.2019.03.028

    authors： Kasinathan G,Sahu SS,Nallan K,Tharmalingam V,Swaminathan S,Behera KP,Pradhan MM,Purusothaman J

    更新日期：2019-06-01 00:00:00

  • Sequence analysis in partial genes of five isolates of Angiostrongylus cantonensis from Taiwan and biological comparison in infectivity and pathogenicity between two strains.

    abstract：:Angiostrongylus cantonensis is the most common infectious agent causing eosinophilic meningitis and is present in Taiwan, Thailand and the Pacific islands. Clinical symptoms vary within different endemic regions, and their severity is probably dependent on the number of ingested parasites and the diversity among strai...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/j.actatropica.2014.01.010

    authors： Lee JD,Chung LY,Wang LC,Lin RJ,Wang JJ,Tu HP,Wu ZD,Yen CM

    更新日期：2014-05-01 00:00:00

  • Development and sexual maturation of Echinococcus granulosus adult worms in the alternative definitive host, Mongolian gerbil (Meriones unguiculatus).

    abstract：:In the present study for the first time an alternative definitive host model has been established for the complete development of Echinococcus granulosus in Meriones unguiculatus (Mongolian gerbils) up to shelled eggs production, as happened in the natural host. Animals treated with methylprednisolone acetate were ora...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/j.actatropica.2005.08.009

    authors： Conchedda M,Gabriele F,Bortoletti G

    更新日期：2006-02-01 00:00:00

  • Factors influencing the prevalence of trypanosome infection of Glossina pallidipes on the Ruvu flood plain of Eastern Tanzania.

    abstract：:We report the pattern of infection of Glossina pallidipes with Trypanosoma vivax and T. congolense at a site in the Coast region of eastern Tanzania, studied between November 1993 and December 1994. Of the 2315 flies dissected 114 (4.9%) were T. congolense positive, 77 (3.3%) were T. vivax positive and 2 (0.1%) were T...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/s0001-706x(98)00013-8

    authors： Msangi AR,Whitaker CJ,Lehane MJ

    更新日期：1998-06-30 00:00:00

  • Development of loop-mediated isothermal amplification (LAMP) for detection of Theileria equi.

    abstract：:Several approaches have been developed for diagnosis of Theileria equi infection in horses and donkeys but all of them have limitations in practice. Due to numerous strengths including easy operation, cheapness and high sensitivity and specificity, LAMP has been already extensively used for surveillance of a number of...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/j.actatropica.2013.05.007

    authors： Xie J,Liu G,Tian Z,Luo J

    更新日期：2013-09-01 00:00:00

  • Heterogeneous distribution of Culex pipiens, Culex quinquefasciatus and their hybrids along the urbanisation gradient.

    abstract：:The mosquitoes of the Culex pipiens complex, hereafter referred to as the Pipiens Assemblage, are vectors of arbovirus of worldwide concern including West Nile and St. Louis encephalitis. Given their distinct eco-physiology and vectorial capacity, accurate specimen identification and insight in the environmental drive...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/j.actatropica.2017.11.017

    authors： Cardo MV,Rubio A,Junges MT,Vezzani D,Carbajo AE

    更新日期：2018-02-01 00:00:00

  • Role of acceptability barriers in delayed diagnosis of Tuberculosis: Literature review from high burden countries.

    abstract：PURPOSE:Direct transmission of mutated tuberculosis (TB) strains is among major contributors to the worldwide epidemic of Drug-Resistant Tuberculosis. Expanding access to TB-services and decreasing diagnostic delays are acknowledged as potential solutions. We aimed to summarize evidence about links between health care ...

    journal_title：Acta tropica

    pub_type： 杂志文章,评审

    doi：10.1016/j.actatropica.2016.06.014

    authors： Barnabishvili M,Ulrichs T,Waldherr R

    更新日期：2016-09-01 00:00:00

  • Concomitant pleural and disseminated tuberculosis in AIDS: immune response or HIV infection compartmentalization?

    abstract：:Although, pleural (PT) and disseminated tuberculosis (DT) have been considered as extreme endpoints of the Th1-Th2 immunological spectrum of the Mycobacterium tuberculosis infection, these conditions can occur together. The presence of PT and DT could be explained by (1) PT as primary condition, with progression of HI...

    journal_title：Acta tropica

    pub_type： 杂志文章,评审

    doi：10.1016/j.actatropica.2007.07.009

    authors： Tuon FF,Tonacio AC,Gryschek RC

    更新日期：2007-11-01 00:00:00

  • Protection against mosquito vectors Aedes aegypti, Anopheles stephensi and Culex quinquefasciatus using a novel insect repellent, ethyl anthranilate.

    abstract：:Growing concern on the application of synthetic mosquito repellents in the recent years has instigated the identification and development of better alternatives to control different mosquito-borne diseases. In view of above, present investigation evaluates the repellent activity of ethyl anthranilate (EA), a non-toxic...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/j.actatropica.2017.06.024

    authors： Islam J,Zaman K,Tyagi V,Duarah S,Dhiman S,Chattopadhyay P

    更新日期：2017-10-01 00:00:00

  • Immune serum from both susceptible and resistant strains of mice increases phagocytosis of Leishmania mexicana amazonensis by macrophages.

    abstract：:Immune sera obtained from either BALB/c mice (susceptible) at 7 weeks, or C57BL/6 mice (resistant), at 7 weeks after infection with L. m. amazonensis, were effective in increasing internalization of homologous promastigotes into starch-induced peritoneal macrophages (from both mouse strains). Both the internalization ...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：

    authors： Reis MG,Roters SB,Barral-Netto M

    更新日期：1987-09-01 00:00:00

  • Studies on the ecology of Bulinus globosus, the intermediate host of Schistosoma haematobium in the Ifakara area, Tanzania.

    abstract：:During a period of 2 years, the ecology of Bulinus globosus was studied in 8 habitats in two streams near Ifakara, SE-Tanzania. The relative Bulinus densities were followed monthly. Two different methods for estimating snail densities (man/time vs. palmleaf traps) gave comparable results. Bulinus densities were consta...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：

    authors： Marti HP,Tanner M,Degrémont AA,Freyvogel TA

    更新日期：1985-06-01 00:00:00

  • Foodborne intestinal flukes: A brief review of epidemiology and geographical distribution.

    abstract：:Foodborne intestinal flukes are highly diverse consisting of at least 74 species with a diverse global distribution. Taxonomically they include 28 species of heterophyids, 23 species of echinostomes, and 23 species of miscellaneous groups (amphistomes, brachylaimids, cyathocotylids, diplostomes, fasciolids, gymnophall...

    journal_title：Acta tropica

    pub_type： 杂志文章,评审

    doi：10.1016/j.actatropica.2019.105210

    authors： Chai JY,Jung BK

    更新日期：2020-01-01 00:00:00

  • Schistosomiasis infection in relation to the ABO blood groups among school children in Zimbabwe.

    abstract：:The study aimed to establish if there was any relationship between the blood group of the human host and schistosomiasis prevalence, intensity, incidence and related organ pathology. Urine and stool specimens were collected from the 735 school children attending a rural school in Zimbabwe to determine the Schistosoma ...

    journal_title：Acta tropica

    pub_type： 杂志文章

    doi：10.1016/s0001-706x(97)00671-2

    authors： Ndamba J,Gomo E,Nyazema N,Makaza N,Kaondera KC

    更新日期：1997-05-30 00:00:00