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Primary Mediastinal Pure Seminomatous Germ Cell Tumor (Germinoma) as a Rare Cause of Precocious Puberty in a 9-Year-Old Patient.

Abstract：

:Less than 5%-7% of germ cell tumors are extragonadal, with the central nervous system being the most common location in children, followed by retroperitoneum and mediastinum. Only 10% of mediastinal tumors are malignant and one-third of these are pure seminomas (germinomas). We report the case of a 9-year-old boy with development of secondary sexual characteristics. Beta-human chorionic gonadotropin was elevated and a mediastinal mass was found. Final histology showed a pure seminomatous germ cell tumor. To our knowledge, this is the first report of a boy with precocious puberty secondary to a mediastinal germinoma.

journal_name

Urology

journal_title

Urology

authors

Bravo-Balado A,Torres Castellanos L,Carrillo Rodríguez A,Gómez Zapata D,Lammoglia Hoyos JJ,Andrade R,Pérez Niño J

doi

10.1016/j.urology.2017.08.038

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

216-219

eissn

0090-4295

issn

1527-9995

pii

S0090-4295(17)30912-3

journal_volume

110

pub_type

杂志文章

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