Abstract：
OBJECTIVE:To prospectively validate the chronic orchialgia symptom index (COSI), a newly created instrument with 12 questions in 3 domains (pain, sexual symptoms and quality of life). METHODS:The COSI was given to 170 men with chronic orchialgia at 2 institutions. Seventy-eight men repeated the COSI before therapy and 42 repeated it after surgical therapy. Data was analyzed for test/retest internal reliability, internal consistency, floor and ceiling effects, construct validity, responsiveness and linear regression of all questions including age, duration, and prior surgeries. RESULTS:The 170 men had a mean age of 44.3 (range 18-82) and median symptom duration of 24 months (3-420). About 22.4% had prior vasectomy, 12.4% had hernia repair, and 12.9% had other prior surgery. Mean total COSI was 20.0±7.7 (range 1-37) with subscores of pain 9.1±3.5 (0-17), sexual symptoms 1.82±1.5 (0-5) and quality of life 9.0±4.0 (0-15). Test/retest reliability was high with mean retest total score of 21.2±7.9 and intraclass correlation coefficient of 0.82. Internal consistency by Cronbach's alpha was 0.86. There were no floor or ceiling effects for total score. Construct validity showed all items contributed to a good fit model (P = .001). Patient age, duration, and prior surgeries did not influence COSI. Finally, the COSI was responsive to improvement after therapy (mean after treatment 13.5±9.8, P = .00001). CONCLUSION:COSI is a valid and clinically relevant symptom index to assess severity of orchialgia symptoms and response to therapy in this challenging patient population.
journal_name
Urologyjournal_title
Urologyauthors
Shoskes DA,Calixte N,Tadros N,Li J,Parekattil Sdoi
10.1016/j.urology.2018.05.030subject
Has Abstractpub_date
2018-09-01 00:00:00pages
39-43eissn
0090-4295issn
1527-9995pii
S0090-4295(18)30550-8journal_volume
119pub_type
杂志文章相关文献
UROLOGY文献大全abstract：OBJECTIVES:To assess, in our contemporary radical cystectomy (RC) series, female sexual dysfunction and whether the type of diversion affected the occurrence of sexual dysfunction. Outcome data after RC with and without orthotopic diversion has focused primarily on cure, urethral recurrence, and continence. METHODS:Th...
journal_title：Urology
pub_type： 临床试验,杂志文章
doi：10.1016/j.urology.2003.12.034
更新日期：2004-06-01 00:00:00
abstract：OBJECTIVE:To compare our initial robotic-assisted nephroureterectomy (RAN) experience with a well-established practice of performing laparoscopic nephroureterectomy (LN) to treat upper tract urothelial carcinoma (UTUC). METHODS:We reviewed our prospectively maintained minimally invasive surgery database. Patients who ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2013.07.079
更新日期：2014-02-01 00:00:00
abstract：OBJECTIVES:To evaluate the long-term hemostatic efficacy of a new high-intensity collimated ultrasonic (HICU) applicator for open subhilar partial nephrectomy (PN) in the porcine model. METHODS:An applicator was designed with a planar 3.78-MHz HICU transducer and a reflector to optimize the delivery of acoustic energy...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2006.02.006
更新日期：2006-07-01 00:00:00
abstract：:A case of bilateral metachronous renal cell carcinoma with gallbladder and pancreatic metastases, presenting with hematobilia and anemia is presented. The presentation of metastatic renal cell carcinoma with hematobilia and anemia is previously unreported. This case illustrates (1) the occasionally very long interval ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(05)80084-6
更新日期：1991-08-01 00:00:00
abstract：OBJECTIVES:Prior investigations evaluating the presence of human papillomavirus (HPV) in prostatic tissue by polymerase chain reaction (PCR) technology have yielded detection rates of 0% to 100%. Contamination by viral DNA from prostatic urethral colonization or less than optimal laboratory conditions have been suggest...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/S0090-4295(97)00126-X
更新日期：1997-07-01 00:00:00
abstract：:A new type of nephrostomy is described with the following main characteristics: it uses a small multiperforated Silastic tube; its crosswise location allows perfect drainage of all of the calyces and the pelvis; it does not become obstructed nor move from its position; and it causes minimum traumatization of the renal...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(77)90305-3
更新日期：1977-06-01 00:00:00
abstract：:Three patients with four renoureteral units have undergone single-stage reconstruction involving ureteroureterostomy and ipsilateral ureteroneocystostomy following temporary loop cutaneous ureterostomy. Preliminary loop cutaneous ureterostomy diversion allowed adequate ureteral recompensation such that ureteral taperi...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(78)90091-2
更新日期：1978-02-01 00:00:00
abstract：OBJECTIVES:In 2001, we reported a novel technique for pediatric circumcision that has proved to be fast, reliable, and safe during the past 4 years, with good cosmetic results. Inspired by our success with this technique, we have created a similar device to be used for adults. METHODS:We conducted a prospective, rando...
journal_title：Urology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.urology.2010.02.021
更新日期：2010-10-01 00:00:00
abstract：OBJECTIVES:To obtain data concerning the incidence and management of reservoir herniation in inflatable penile prosthesis surgery in a clinical investigation. Reservoir herniation after scrotal placement of inflatable penile prosthesis is an unusual complication, and a review of the published medical reports reveals on...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(00)00864-5
更新日期：2001-01-01 00:00:00
abstract：OBJECTIVE:To compare the results of polymerase chain reaction (PCR) and immunologic methods for the detection of nanobacteria (NB) in the expressed prostatic secretions (EPSs) of patients with type-III prostatitis. METHODS:In total, 150 patients with type-III prostatitis for whom conventional clinical treatment had fa...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2014.05.038
更新日期：2014-09-01 00:00:00
abstract：OBJECTIVE:To investigate the role of fatty acid synthase (FASN) in bladder transitional cell carcinoma (BTCC). METHODS:FASN expression was investigated in non-muscle-invasive BTCC tissue specimens by immunohistochemistry and BTCC cell lines by Western blot. After treatment with FASN-siRNA or FASN inhibitor cerulenin (...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2012.02.046
更新日期：2012-08-01 00:00:00
abstract：:Cytologic differences in the urine of 6 patients with transitional cell carcinoma in situ (CIS) of the urinary bladder with and without prostatic duct involvement are described. In the former group, there was an admixture of CIS cells along with many bizarre malignant cells which increased with time and showed maligna...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(76)90203-x
更新日期：1976-05-01 00:00:00
abstract：:Bladder reconstruction, either by augmentation or substitution enterocystoplasty, is a safe alternative to supravesical urinary diversion providing careful attention to preoperative selection, surgical technique, and postoperative review is observed. However, under the most optimal conditions an untoward outcome may o...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(92)90428-y
更新日期：1992-07-01 00:00:00
abstract：OBJECTIVES:Chronic scrotal pain is a frequent complaint. In many patients with scrotal pain, scrotal ultrasound is performed when the physical examination reveals no abnormalities. We evaluated the yield of scrotal ultrasound in patients with chronic scrotal pain and a normal physical examination. METHODS:The study in...
journal_title：Urology
pub_type： 临床试验,杂志文章
doi：10.1016/s0090-4295(99)00352-0
更新日期：1999-12-01 00:00:00
abstract：:Although cystitis glandularis has been considered a premalignant lesion, the instance of cystitis glandularis progression to adenocarcinoma or cystitis glandularis associated with adenocarcinomatous change is rare. This article includes 4 cases of neurogenic bladder with urinary diversion for different periods of time...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(80)90484-7
更新日期：1980-04-01 00:00:00
abstract：:Priapism was associated with multiple myeloma and hyperviscosity in a sixty-year-old black male. Plasmapheresis treatment of the hyperviscosity corrected his priapism, and chemotherapy for the underlying multiple myeloma prevented the recurrence of priapism after a chronic intermittent history of seventeen years. ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(78)90334-5
更新日期：1978-08-01 00:00:00
abstract：:Adult Wilms tumor is still considered a rarity. Approximately 170 adult Wilms tumors have been reported. The final diagnosis is usually established with surgery. There is no specific radiologic diagnosis of adult Wilms tumor. We report on a case of Wilms tumor in a twenty-two-year-old black man. The tumor was removed ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(87)90182-8
更新日期：1987-08-01 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy and safety of wideband Doppler ultrasound-guided mini-endoscopic combined intrarenal surgery (mini-ECIRS) for large renal stones. MATERIALS AND METHODS:This study included 41 patients with large renal stones (>30 mm) treated by mini-ECIRS using a retrograde flexible ureteroscope and ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2016.05.038
更新日期：2016-09-01 00:00:00
abstract：OBJECTIVE:To characterize the interactions between the cholinergic and prostaglandin signaling systems within the urothelium-lamina propria of the guinea pig and elucidate the role of muscarinic receptors in these interactions. METHODS:The urothelium-lamina propria was isolated from guinea pig bladders, cut into strip...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2011.08.029
更新日期：2012-01-01 00:00:00
abstract：OBJECTIVES:To present outcomes of a contemporary series of patients undergoing radical cystectomy (RC) for bladder cancer after previous treatment for localized cancer of the prostate (CaP). METHODS:A retrospective review of more than 1000 RCs performed for bladder cancer between 1995 and 2008 identified 49 patients p...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2010.01.048
更新日期：2010-12-01 00:00:00
abstract：OBJECTIVES:To assess sexual dysfunction in sexually active men after radical cystectomy (RC) and to determine whether sildenafil citrate can improve erectile dysfunction after surgery. METHODS:The baseline and follow-up data from 49 sexually active male patients (mean age 57.8 +/- 9.1 years) undergoing RC (1995 to 200...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2004.05.056
更新日期：2004-10-01 00:00:00
abstract：OBJECTIVE:This study reviews the incidence and management of cyclophosphamide-induced hemorrhagic cystitis in a group of patients who received high-dose chemotherapy and bone marrow transplantation. METHODS:The records of 217 consecutive patients undergoing bone marrow transplantation were reviewed. The incidence, deg...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(94)90079-5
更新日期：1994-03-01 00:00:00
abstract：:Use of α-blockers for medical expulsive therapy (MET) has been the subject of huge debate in urology. Moreover, there have been a number of randomized controlled trials with differing results. We conducted a systematic review and meta-analysis of randomized controlled trials investigating the efficacy of α-blockers fo...
journal_title：Urology
pub_type： 杂志文章,meta分析
doi：10.1016/j.urology.2018.03.028
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVE:To study the feasibility of robot-assisted laparoscopic ureterolithotomy for large (>2 cm) or impacted lower ureteral stones and the immediate outcome measures such as the stone-free rate and occurrence of intra- and postoperative complications. MATERIALS AND METHODS:From April 2010 to August 2012, 52 roboti...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2013.02.059
更新日期：2013-07-01 00:00:00
abstract：:In patients who have undergone complex genitourinary reconstruction, additional abdominal surgery is often required. We report 2 cases in which the blood supply to an existing Mitrofanoff channel was divided. In both cases, the conduits appeared to remain well perfused, presumably based on collateral blood supply. Bot...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2005.03.013
更新日期：2005-09-01 00:00:00
abstract：:We present the eighth case of testicular extrusion through a congenital defect in the scrotal wall, along with a review of the published reports and a discussion of its possible embryogenesis. ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(02)02003-4
更新日期：2002-12-01 00:00:00
abstract：:Nuclear DNA content of paraffin-embedded tissue from 19 clinically benign adrenal pheochromocytomas and 18 control adrenal glands was analyzed using flow cytometry. All control adrenal glands and 6 pheochromocytomas were diploid. Four tumors were tetraploid. Nine were aneuploid with relative DNA indices in the near di...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(87)90171-3
更新日期：1987-08-01 00:00:00
abstract：OBJECTIVE:To perform patient-specific meta-analysis (MA) of two independent clinical validation studies of a 17-gene biopsy-based genomic assay as a predictor of favorable pathology at radical prostatectomy. MATERIALS AND METHODS:Patient-specific MA was performed on data from 2 studies (732 patients) using the Genomic...
journal_title：Urology
pub_type： 杂志文章,meta分析
doi：10.1016/j.urology.2015.12.008
更新日期：2016-03-01 00:00:00
abstract：:Insertion of either a semirigid or inflatable penile prosthesis at the completion of surgery for various malignancies was performed. Twelve men had implants and were followed at least one year with excellent results. Careful preoperative sexual counseling with the patient's spouse is recommended and adds immeasureably...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(82)90637-9
更新日期：1982-09-01 00:00:00
abstract：OBJECTIVE:To present a novel method to increase injection force of medication into very fibrotic and sometimes calcified plaques in patients with Peyronie's disease and try to improve infiltration of the drug inside the plaque. METHODS:We adapted a simple commercial inflation device, commonly used in other surgical fi...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2013.07.011
更新日期：2013-11-01 00:00:00
