What Is the Role of α-Blockers for Medical Expulsive Therapy? Results From a Meta-analysis of 60 Randomized Trials and Over 9500 Patients.

Abstract:

:Use of α-blockers for medical expulsive therapy (MET) has been the subject of huge debate in urology. Moreover, there have been a number of randomized controlled trials with differing results. We conducted a systematic review and meta-analysis of randomized controlled trials investigating the efficacy of α-blockers for MET. This review confirms there is a role for α-blockers in MET for ureteric stones specifically in stones >5 mm and distal ureteric stones, which is associated with improved stone expulsion. However, there is a slight increase in risk of nonsignificant side effects.

journal_name

Urology

journal_title

Urology

authors

Aboumarzouk OM,Jones P,Amer T,Kotsiris D,Emiliani E,Somani B,Kallidonis P,Tailly T,Atis G,Greco F,Hruby S,Alvarez M,Al-Rumaihi K,Shamsodini A,Al-Ansari A,Shokeir A

doi

10.1016/j.urology.2018.03.028

subject

Has Abstract

pub_date

2018-09-01 00:00:00

pages

5-16

eissn

0090-4295

issn

1527-9995

pii

S0090-4295(18)30284-X

journal_volume

119

pub_type

杂志文章,meta分析

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