Abstract：
OBJECTIVES:To investigate whether interstitial laser coagulation (ILC) is as effective and as safe as transurethral resection of the prostate (TURP). The treatment of choice for bladder outflow obstruction secondary to benign prostatic hyperplasia is TURP. However, ILC is a less invasive outpatient procedure that may be as effective and safe as TURP. METHODS:In a multicenter randomized trial at six U.S. tertiary care hospitals, we treated 72 men with bladder outflow obstruction secondary to benign prostatic hyperplasia with either TURP (n = 35) or ILC (n = 37). The outcome measures were peak flow rate, postvoid residual urine volume, prostate volume, prostate-specific antigen levels, symptom and quality-of-life indexes, sexual function, and adverse event rates. Measurements were taken at baseline and at 3, 6, 12, and 24 months. RESULTS:At 2 years, the TURP patients had better median peak flow rates, but not significantly so (range 16.5 to 13.9 mL/s, 95% confidence interval for the 2.6 mL/s difference of -0.4 to 7.6). The median scores on the symptom indexes and quality-of-life measures were similarly improved in both groups. Of 37 ILC patients, 6 (16%) were retreated with TURP in the first year. Sexual function declined in the TURP group but remained stable in the ILC group. The adverse event rates were similar, although the events were more serious in the TURP group. CONCLUSIONS:ILC compares respectably with TURP. Given the advantages of an outpatient procedure, similar results in symptom reduction and quality-of-life measures, and less severe adverse effects, ILC can be an acceptable alternative to TURP.
journal_name
Urologyjournal_title
Urologyauthors
Kursh ED,Concepcion R,Chan S,Hudson P,Ratner M,Eyre Rdoi
10.1016/s0090-4295(02)02420-2subject
Has Abstractpub_date
2003-03-01 00:00:00pages
573-8issue
3eissn
0090-4295issn
1527-9995pii
S0090429502024202journal_volume
61pub_type
临床试验,杂志文章,多中心研究,随机对照试验相关文献
UROLOGY文献大全abstract：OBJECTIVES:Demographic information on patients presenting for the diagnosis and treatment of male factor infertility has been limited in the past by the paucity of subspecialty trained providers and concentrated sequential patient information. Previously reported studies looking at the characteristics of patients being...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(01)01400-5
更新日期：2001-12-01 00:00:00
abstract：:The compartment syndrome is a rare complication of surgery in the lithotomy position, but one that may result in neurovascular damage and permanent disability. Herein, we present a case of bilateral three-compartment syndrome following urethroplasty in the dorsolithotomy position, with review of the literature and dis...
journal_title：Urology
pub_type： 杂志文章,评审
doi：10.1016/0090-4295(94)90204-6
更新日期：1994-05-01 00:00:00
abstract：OBJECTIVES:To perform systemic 22-core transperineal ultrasound-guided template prostate biopsies in patients with previous negative transrectal ultrasound-guided prostate biopsy findings and evaluate the cancer core distribution. METHODS:Between April 2001 and December 2003, 128 men underwent systemic ultrasound-guid...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2005.01.051
更新日期：2005-07-01 00:00:00
abstract：OBJECTIVES:Previous studies have observed higher age-specific serum prostate-specific antigen (PSA) values in African-American (AA) men without prostate cancer compared to white men, leading some to recommend race-specific PSA reference ranges for the early detection of prostate cancer. The primary objective of the Fli...
journal_title：Urology
pub_type： 杂志文章,评审
doi：10.1016/s0090-4295(00)00873-6
更新日期：2001-01-01 00:00:00
abstract：OBJECTIVES:To examine retrospectively the clinical presentations, microbiologic characteristics, and treatment outcomes of psoas abscess in patients with diabetes mellitus (DM) and to assess the usefulness of computed tomography and gallium-67 scanning in its early diagnosis. METHODS:During a 9-year period, psoas absc...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(00)00923-7
更新日期：2001-02-01 00:00:00
abstract：OBJECTIVE:To determine (1) the frequency of testosterone (T) use in 2 academic male infertility practices, (2) the effect on semen parameters, and (3) the potential for reversibility. METHODS:We performed a retrospective review. Inclusion criteria were supplemental T usage at the time of initial visit, T cessation, an...
journal_title：Urology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.urology.2014.12.052
更新日期：2015-05-01 00:00:00
abstract：OBJECTIVE:To evaluate the consequence of pharmacologic inhibition of voltage-gated Na(+) channels (Nav) in the conscious rat, based on Nav having been implicated as modulators of rodent urodynamics using knockout as well as antisense oligodeoxynucleotide approaches. METHODS:The urodynamic response to standard Nav bloc...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2012.02.016
更新日期：2012-06-01 00:00:00
abstract：OBJECTIVES:To perform a prospective, placebo-controlled study to examine the long-term efficacy of alfuzosin compared with placebo and standard therapy in patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), because alpha-blockers have been suggested for the treatment of CP/CPPS. METHODS:One hundr...
journal_title：Urology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0090-4295(03)00466-7
更新日期：2003-09-01 00:00:00
abstract：:With recent advances in ultrasound technology, concomitant improvement in sonographic techniques have been required. Sonographic scanning in coronal orientation, both in transverse but especially in longitudinal direction, has demonstrated a number of advantages over the routine transverse and sagittal scans. Closer c...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(81)90025-x
更新日期：1981-01-01 00:00:00
abstract：:A man interested in active surveillance of low-risk prostate cancer sought a second opinion after having undergone an inappropriate metastatic evaluation that demonstrated multiple enhancing liver masses. Because of his history of splenectomy for trauma, hepatic splenosis was suspected. Despite reassurance, the patien...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2011.09.041
更新日期：2012-05-01 00:00:00
abstract：OBJECTIVES:To evaluate the effectiveness and safety of a new purified collagen gel with specific properties for renal artery embolization in an experimental model in dogs. METHODS:The new gel was prepared from type I bovine tendon collagen, highly purified to eliminate immunogenicity, and reconstituted through extensi...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2005.10.043
更新日期：2006-04-01 00:00:00
abstract：:Clinical and radiographic evaluation of a fifty-six-year-old male with microscopic hematuria led to radical nephrectomy for renal cell carcinoma. Histologic examination by light and electronmicroscopy was most compatible with malignant schwannoma. The tumor was close to the kidney without actual renal involvement. Thi...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(78)90173-5
更新日期：1978-05-01 00:00:00
abstract：OBJECTIVES:To more clearly elucidate the relationship between prostate volume (PV) and prostate cancer parameters. METHODS:The Urologic Oncology Database was reviewed. A total of 3460 patients had undergone radical prostatectomy from 1988 to 2006. Of these, 2600 with complete data were included in the study and were s...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2007.05.022
更新日期：2007-10-01 00:00:00
abstract：:Renal rhabdomyosarcoma (RMS) is a rare pediatric tumor. Pancake kidneys are unusual anatomic anomalies resulting when both upper and lower poles of the embryonic kidney become fused. We report on a 4-year-old boy who was discovered to have a stage 4, group IV renal embryonal RMS arising from a pancake kidney with meta...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2013.03.003
更新日期：2013-08-01 00:00:00
abstract：OBJECTIVES:To define the responses of stretched penile length (PL) to intramuscular testosterone enanthate (TE) treatment in prepubertal boys with hypospadias. METHODS:We examined 17 Japanese boys with hypospadias at 1.4 +/- 1.3 (mean +/- SD) years of age. Their PLs were 2.79 +/- 0.37 cm and -1.16 +/- 0.88 SD of the m...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2009.12.065
更新日期：2010-07-01 00:00:00
abstract：OBJECTIVES:To develop a nomogram that allows the prediction of disease recurrence using preoperative clinical factors for patients with clinically localized prostate cancer who are candidates for laparoscopic radical prostatectomy. Few published studies have combined the clinical prognostic factors into risk profiles t...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2010.05.013
更新日期：2011-02-01 00:00:00
abstract：OBJECTIVES:Contemporary audits and reviews of outcome after transurethral resection of the prostate (TURP) make little reference to failure to void following catheter removal after this operation. There have been few reports of the likelihood of a successful trial without a catheter after TURP related to mode of presen...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(98)00515-9
更新日期：1999-02-01 00:00:00
abstract：OBJECTIVES:To identify the rates of decline in health-related quality of life during the year before death in men with prostate cancer. METHODS:We studied men in a subset analysis within a longitudinal, observational cohort of patients with metastatic prostate cancer at the University of California, Los Angeles, Cente...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(01)01457-1
更新日期：2002-01-01 00:00:00
abstract：:We report a case of a single system solitary ectopic ureter to the rectum with bladder agenesis in a viable newborn male. Only 2 cases of ectopic ureter to the rectum and 18 cases of bladder agenesis have been reported in viable newborns. To our knowledge, this case constitutes the first reported combination of these ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2006.09.048
更新日期：2006-12-01 00:00:00
abstract：:Metastasis of gastric carcinoma to the ureter is very rare. In most published cases, the diagnosis is only made at postmortem examination or when gross metastasis is present. This report presents a case in which the metastasis occluded the ureteral lumen from inside, and the diagnosis was made by histopathologic exami...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(99)00169-7
更新日期：1999-09-01 00:00:00
abstract：OBJECTIVE:To assess the contemporary epidemiology of blunt trauma lower urinary tract injury (LUTI) and to evaluate outcomes in patients with and without associated pelvic fracture (PF). METHODS:Patients presenting to our level I trauma center with PF and/or LUTI from blunt trauma from 2000 to 2014 were identified in ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2016.11.015
更新日期：2017-04-01 00:00:00
abstract：:The literature on epidermoid cyst of the testis is reviewed, and 2 additional cases are presented. Etiology and pathology of the disease are discussed. Our review revealed that 85 per cent of patients have undergone orchiectomy for this benign disease. Diagnostic characteristics of this lesion are emphasized so that i...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(77)90228-x
更新日期：1977-04-01 00:00:00
abstract：OBJECTIVE:To introduce the new preoperative parameter as a predictor for extracapsular extension (ECE), we defined the presence of tumor at the stump of the rectum side on prostate needle biopsy as a positive posterior margin (PPM), and speculated that PPM is related to ECE. METHODS:This retrospective study was conduc...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2012.12.050
更新日期：2013-05-01 00:00:00
abstract：:Malignant ovarian-type surface epithelial tumors of the testis and paratestis are rare neoplasms. The chemosensitivity of these tumors has not been previously documented. We report a patient with metastatic disease with demonstrated responsiveness to chemotherapy treatments used in advanced ovarian cancer. ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2005.03.032
更新日期：2005-09-01 00:00:00
abstract：OBJECTIVE:To compare the PERC-tic technique, described as placement of dual wires under fluoroscopic guidance adjacent to the stone within the obstructed calyx, to standard percutaneous nephrolithotomy (PCNL) with working wires secured down the ureter. MATERIALS AND METHODS:This is a retrospective cohort study of pati...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2019.12.040
更新日期：2020-06-01 00:00:00
abstract：:Nonoperative ablation of the testicular artery has been described in animals using the Burdizzo clamp, but not in humans. We report a case of incisionless castration performed using local anesthesia, in a transsexual who wished to avoid the pain, expense, and scar associated with the open procedure. The Burdizzo clamp...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(02)01608-4
更新日期：2002-06-01 00:00:00
abstract：:In 83 patients with non-neurologic, nonoperated vesicoureteral reflux the relation between enuresis and nephropathy was analyzed. The material showed that in spite of identical age, sex distribution, previous history of recurrent urinary tract infections, and the number of refluxing units, patients with enuresis showe...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(85)90156-6
更新日期：1985-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the impact of early hospital admission and onset of medical expulsive therapy (MET) in spontaneous passage of ureteral stones causing renal colic. METHODS:We recruited 392 patients referred to the emergency room with symptoms of renal colic. All patients received standard MET of oral tamsulosin 0...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2014.01.005
更新日期：2014-07-01 00:00:00
abstract：:Long-term analyses of the UroLume Endoprosthesis have shown conflicting results with regard to efficacy and restricture rates. The best management of recurrent urethra stricture disease at the site of a previous UroLume stent is unknown. We describe a previously unreported technique for transperineal excision of the U...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2005.08.038
更新日期：2006-02-01 00:00:00
abstract：OBJECTIVES:Transformation of normal epithelium into cancer cells involves epigenetic and genetic changes and modifications in nuclear structure and tissue architecture. To evaluate nuclear morphometric alterations and clinicopathologic features for organ- vs nonorgan-confined prostate carcinoma (PCa) prediction. METHO...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2008.09.060
更新日期：2009-05-01 00:00:00
