Abstract：
:Exercise training (ExT) is widely used for the prevention and treatment of several chronic cardiovascular diseases. However, only recently it started to be recognized as safe and beneficial in pulmonary arterial hypertension. Despite the consistency of its favorable effects on exercise tolerance and quality of life, the mechanisms underlying these meaningful clinical improvements remain unclear. Current studies emphasize the exercise-induced changes on skeletal muscle but the impact of ExT at the level of the pulmonary circulation and right ventricle should not be overlooked. In this chapter, we summarize the main findings from pre-clinical studies analyzing the impact of exercise in pulmonary hypertension and right heart failure.
journal_name
Adv Exp Med Bioljournal_title
Advances in experimental medicine and biologyauthors
Moreira-Gonçalves D,Ferreira-Nogueira R,Santos M,Silva AF,Ferreira R,Leite-Moreira A,Duarte JA,Henriques-Coelho Tdoi
10.1007/978-981-10-4307-9_17subject
Has Abstractpub_date
2017-01-01 00:00:00pages
307-324eissn
0065-2598issn
2214-8019journal_volume
999pub_type
杂志文章,评审abstract：:Bovine milk will eventually spoil at refrigeration temperatures, but endogenous or exogenous pathogenic or spoilage bacteria in human milk stored for delayed feeding will die. We investigated the mechanism for these antibacterial properties and their response to high-tempertature, short-time (HTST, 72 degrees C-75 deg...
journal_title：Advances in experimental medicine and biology
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doi：
更新日期：2001-01-01 00:00:00
abstract：:The initiation of microglial responses to the ischemic injury involves modifications of calcium homeostasis. Changes in [Ca(2+)](i) levels have also been shown to influence the developmental processes that accompany the transition of human oligodendrocyte precursor cells (OPCs) into mature myelinating oligodendrocytes...
journal_title：Advances in experimental medicine and biology
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doi：10.1007/978-1-4419-7046-6_30
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abstract：:Here we propose a model of a peripheral axon with a great deal of autonomy from its cell body-the autonomous axon-but with a substantial dependence on its ensheathing Schwann cell (SC), the axon-SC unit. We review evidence in several fields and show that (i) axons can extend sprouts and grow without the concurrence of...
journal_title：Advances in experimental medicine and biology
pub_type： 杂志文章,评审
doi：10.1007/978-3-319-40764-7_9
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journal_title：Advances in experimental medicine and biology
pub_type： 杂志文章,评审
doi：10.1007/978-3-030-37639-0_8
更新日期：2020-01-01 00:00:00
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journal_title：Advances in experimental medicine and biology
pub_type： 杂志文章
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更新日期：1998-01-01 00:00:00
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journal_title：Advances in experimental medicine and biology
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pub_type： 杂志文章,评审
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pub_type： 杂志文章,评审
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更新日期：2008-01-01 00:00:00
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journal_title：Advances in experimental medicine and biology
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更新日期：2015-01-01 00:00:00
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journal_title：Advances in experimental medicine and biology
pub_type： 杂志文章
doi：10.1007/978-3-319-93791-5_5
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journal_title：Advances in experimental medicine and biology
pub_type： 杂志文章,评审
doi：10.1007/978-3-319-33826-2_14
更新日期：2016-01-01 00:00:00
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journal_title：Advances in experimental medicine and biology
pub_type： 杂志文章,评审
doi：10.1007/978-981-10-6955-0_20
更新日期：2017-01-01 00:00:00
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pub_type： 杂志文章
doi：10.1007/978-1-4613-2463-8_57
更新日期：1985-01-01 00:00:00
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journal_title：Advances in experimental medicine and biology
pub_type： 杂志文章,评审
doi：10.1007/978-1-4614-4756-6_36
更新日期：2013-01-01 00:00:00
abstract：:In this chapter, we will review studies of HER2 in osteosarcoma and discuss the controversies that have existed in this field. Our present understanding of HER2 in the context of osteosarcoma is that it is expressed on a subset of patient samples, but that expression is not prognostic. We will review the two trials th...
journal_title：Advances in experimental medicine and biology
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doi：10.1007/978-3-030-43032-0_5
更新日期：2020-01-01 00:00:00
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journal_title：Advances in experimental medicine and biology
pub_type： 杂志文章
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journal_title：Advances in experimental medicine and biology
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doi：
更新日期：1979-01-01 00:00:00
abstract：:Voltage- and ligand-gated ion channels are key elements in the etiopathogenesis of various forms of epilepsy. In this chapter, we present an overview of the functional implications of voltage-gated Ca(2+) channels in modulating internal Ca(2+) level fluctuations and generating ictiform/epileptiform cellular electrophy...
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更新日期：2016-01-01 00:00:00
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journal_title：Advances in experimental medicine and biology
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pub_type： 杂志文章,评审
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journal_title：Advances in experimental medicine and biology
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abstract：:Calcium absorption in the large intestine was studied under physiological conditions in the rat. When 45Ca was administered directly into the caecum, the isotope was significantly absorbed. This absorption was modulated by dietary Ca and Pi as well as by the 1,25(OH) D3 status. On the other hand, calcium coming from t...
journal_title：Advances in experimental medicine and biology
pub_type： 杂志文章
doi：10.1007/978-1-4684-5206-8_29
更新日期：1986-01-01 00:00:00
abstract：:Most processes of human body, such as brain function, are regulated by biological rhythms. Disturbance of biological rhythms impairs mood, behavior, cognition, sleep, and social activity and may lead to mental disorders. Disturbed rhythms are widely observable in patients with major depressive disorders (MDD) and make...
journal_title：Advances in experimental medicine and biology
pub_type： 杂志文章,评审
doi：10.1007/978-981-32-9271-0_6
更新日期：2019-01-01 00:00:00
