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Modification of the classical Lancefield assay of group A streptococcal killing to reduce inter-donor variation.

Abstract：

:The lack of a surrogate-of-immunity assay presents a major barrier to Streptococcus pyogenes research. Modification of the Lancefield assay to include an antibody digestion step reduced inter-donor variation and permitted detection of the anti-streptococcal activity of intravenous immunoglobulin and convalescent serum, thus facilitating retrospective evaluation of immunity using stored samples.

journal_name

J Microbiol Methods

journal_title

Journal of microbiological methods

authors

Reglinski M,Lynskey NN,Sriskandan S

doi

10.1016/j.mimet.2016.03.015

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

69-71

eissn

0167-7012

issn

1872-8359

pii

S0167-7012(16)30050-1

journal_volume

124

pub_type

杂志文章

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